D L Hertz, H L McLeod. Clin Pharmacol Ther 2016
Times Cited: 12
Times Cited: 12
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CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network.
M V Relling, T E Klein. Clin Pharmacol Ther 2011
M V Relling, T E Klein. Clin Pharmacol Ther 2011
41
Genotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: a multicenter study.
William J Irvin, Christine M Walko, Karen E Weck, Joseph G Ibrahim, Wing K Chiu, E Claire Dees, Susan G Moore, Oludamilola A Olajide, Mark L Graham, Sean T Canale,[...]. J Clin Oncol 2011
William J Irvin, Christine M Walko, Karen E Weck, Joseph G Ibrahim, Wing K Chiu, E Claire Dees, Susan G Moore, Oludamilola A Olajide, Mark L Graham, Sean T Canale,[...]. J Clin Oncol 2011
25
Pharmacogenetics: from bench to byte--an update of guidelines.
J J Swen, M Nijenhuis, A de Boer, L Grandia, A H Maitland-van der Zee, H Mulder, G A P J M Rongen, R H N van Schaik, T Schalekamp, D J Touw,[...]. Clin Pharmacol Ther 2011
J J Swen, M Nijenhuis, A de Boer, L Grandia, A H Maitland-van der Zee, H Mulder, G A P J M Rongen, R H N van Schaik, T Schalekamp, D J Touw,[...]. Clin Pharmacol Ther 2011
25
Pharmacogenomics: "noninferiority" is sufficient for initial implementation.
R B Altman. Clin Pharmacol Ther 2011
R B Altman. Clin Pharmacol Ther 2011
25
Advancing Pharmacogenomics as a Component of Precision Medicine: How, Where, and Who?
J A Johnson, K W Weitzel. Clin Pharmacol Ther 2016
J A Johnson, K W Weitzel. Clin Pharmacol Ther 2016
16
Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting.
L V Kalman, Jag Agúndez, M Lindqvist Appell, J L Black, G C Bell, S Boukouvala, C Bruckner, E Bruford, K Caudle, S A Coulthard,[...]. Clin Pharmacol Ther 2016
L V Kalman, Jag Agúndez, M Lindqvist Appell, J L Black, G C Bell, S Boukouvala, C Bruckner, E Bruford, K Caudle, S A Coulthard,[...]. Clin Pharmacol Ther 2016
16
Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients.
Kazuma Kiyotani, Taisei Mushiroda, Chiyo K Imamura, Yusuke Tanigawara, Naoya Hosono, Michiaki Kubo, Mitsunori Sasa, Yusuke Nakamura, Hitoshi Zembutsu. Breast Cancer Res Treat 2012
Kazuma Kiyotani, Taisei Mushiroda, Chiyo K Imamura, Yusuke Tanigawara, Naoya Hosono, Michiaki Kubo, Mitsunori Sasa, Yusuke Nakamura, Hitoshi Zembutsu. Breast Cancer Res Treat 2012
16
Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer.
P Saladores, T Mürdter, D Eccles, B Chowbay, N K Zgheib, S Winter, B Ganchev, B Eccles, S Gerty, A Tfayli,[...]. Pharmacogenomics J 2015
P Saladores, T Mürdter, D Eccles, B Chowbay, N K Zgheib, S Winter, B Ganchev, B Eccles, S Gerty, A Tfayli,[...]. Pharmacogenomics J 2015
16
CYP3A4 and seasonal variation in vitamin D status in addition to CYP2D6 contribute to therapeutic endoxifen level during tamoxifen therapy.
Wendy A Teft, Inna Y Gong, Brian Dingle, Kylea Potvin, Jawaid Younus, Theodore A Vandenberg, Muriel Brackstone, Francisco E Perera, Yun-Hee Choi, Guangyong Zou,[...]. Breast Cancer Res Treat 2013
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16
CYP2D6 genotype- and endoxifen-guided tamoxifen dose escalation increases endoxifen serum concentrations without increasing side effects.
V O Dezentjé, F L Opdam, H Gelderblom, J Hartigh den, T Van der Straaten, R Vree, E Maartense, C H Smorenburg, H Putter, A S Dieudonné,[...]. Breast Cancer Res Treat 2015
V O Dezentjé, F L Opdam, H Gelderblom, J Hartigh den, T Van der Straaten, R Vree, E Maartense, C H Smorenburg, H Putter, A S Dieudonné,[...]. Breast Cancer Res Treat 2015
16
CYP2D6 genotypes, endoxifen levels, and disease recurrence in 224 Filipino and Vietnamese women receiving adjuvant tamoxifen for operable breast cancer.
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16
Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials.
C Davies, J Godwin, R Gray, M Clarke, D Cutter, S Darby, P McGale, H C Pan, C Taylor, Y C Wang,[...]. Lancet 2011
C Davies, J Godwin, R Gray, M Clarke, D Cutter, S Darby, P McGale, H C Pan, C Taylor, Y C Wang,[...]. Lancet 2011
16
Tamoxifen metabolite concentrations, CYP2D6 genotype, and breast cancer outcomes.
L Madlensky, L Natarajan, S Tchu, M Pu, J Mortimer, S W Flatt, D M Nikoloff, G Hillman, M R Fontecha, H J Lawrence,[...]. Clin Pharmacol Ther 2011
L Madlensky, L Natarajan, S Tchu, M Pu, J Mortimer, S W Flatt, D M Nikoloff, G Hillman, M R Fontecha, H J Lawrence,[...]. Clin Pharmacol Ther 2011
16
The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.
A Gaedigk, S D Simon, R E Pearce, L D Bradford, M J Kennedy, J S Leeder. Clin Pharmacol Ther 2008
A Gaedigk, S D Simon, R E Pearce, L D Bradford, M J Kennedy, J S Leeder. Clin Pharmacol Ther 2008
16
Interethnic differences in genetic polymorphisms of CYP2D6 in the U.S. population: clinical implications.
Stephen Bernard, Kathleen A Neville, Anne T Nguyen, David A Flockhart. Oncologist 2006
Stephen Bernard, Kathleen A Neville, Anne T Nguyen, David A Flockhart. Oncologist 2006
16
CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations.
M A Province, M P Goetz, H Brauch, D A Flockhart, J M Hebert, R Whaley, V J Suman, W Schroth, S Winter, H Zembutsu,[...]. Clin Pharmacol Ther 2014
M A Province, M P Goetz, H Brauch, D A Flockhart, J M Hebert, R Whaley, V J Suman, W Schroth, S Winter, H Zembutsu,[...]. Clin Pharmacol Ther 2014
16
CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the breast international group 1-98 trial.
Meredith M Regan, Brian Leyland-Jones, Mark Bouzyk, Olivia Pagani, Weining Tang, Roswitha Kammler, Patrizia Dell'orto, Maria Olivia Biasi, Beat Thürlimann, Maria B Lyng,[...]. J Natl Cancer Inst 2012
Meredith M Regan, Brian Leyland-Jones, Mark Bouzyk, Olivia Pagani, Weining Tang, Roswitha Kammler, Patrizia Dell'orto, Maria Olivia Biasi, Beat Thürlimann, Maria B Lyng,[...]. J Natl Cancer Inst 2012
16
CYP2D6 and UGT2B7 genotype and risk of recurrence in tamoxifen-treated breast cancer patients.
James M Rae, Suzy Drury, Daniel F Hayes, Vered Stearns, Jacklyn N Thibert, Ben P Haynes, Janine Salter, Ivana Sestak, Jack Cuzick, Mitch Dowsett. J Natl Cancer Inst 2012
James M Rae, Suzy Drury, Daniel F Hayes, Vered Stearns, Jacklyn N Thibert, Ben P Haynes, Janine Salter, Ivana Sestak, Jack Cuzick, Mitch Dowsett. J Natl Cancer Inst 2012
16
Personalized Critical Care Medicine: How Far Away Are We?
Amy M Ahasic, David C Christiani. Semin Respir Crit Care Med 2015
Amy M Ahasic, David C Christiani. Semin Respir Crit Care Med 2015
25
HLA-B*5701 screening for hypersensitivity to abacavir.
Simon Mallal, Elizabeth Phillips, Giampiero Carosi, Jean-Michel Molina, Cassy Workman, Janez Tomazic, Eva Jägel-Guedes, Sorin Rugina, Oleg Kozyrev, Juan Flores Cid,[...]. N Engl J Med 2008
Simon Mallal, Elizabeth Phillips, Giampiero Carosi, Jean-Michel Molina, Cassy Workman, Janez Tomazic, Eva Jägel-Guedes, Sorin Rugina, Oleg Kozyrev, Juan Flores Cid,[...]. N Engl J Med 2008
16
Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects.
Magnus Ingelman-Sundberg, Sarah C Sim, Alvin Gomez, Cristina Rodriguez-Antona. Pharmacol Ther 2007
Magnus Ingelman-Sundberg, Sarah C Sim, Alvin Gomez, Cristina Rodriguez-Antona. Pharmacol Ther 2007
16
Clinical Pharmacogenetics Implementation Consortium guidelines for HLA-B genotype and carbamazepine dosing.
S G Leckband, J R Kelsoe, H M Dunnenberger, A L George, E Tran, R Berger, D J Müller, M Whirl-Carrillo, K E Caudle, M Pirmohamed. Clin Pharmacol Ther 2013
S G Leckband, J R Kelsoe, H M Dunnenberger, A L George, E Tran, R Berger, D J Müller, M Whirl-Carrillo, K E Caudle, M Pirmohamed. Clin Pharmacol Ther 2013
16
Adoption of pharmacogenomic testing by US physicians: results of a nationwide survey.
E J Stanek, C L Sanders, K A Johansen Taber, M Khalid, A Patel, R R Verbrugge, B C Agatep, R E Aubert, R S Epstein, F W Frueh. Clin Pharmacol Ther 2012
E J Stanek, C L Sanders, K A Johansen Taber, M Khalid, A Patel, R R Verbrugge, B C Agatep, R E Aubert, R S Epstein, F W Frueh. Clin Pharmacol Ther 2012
16
Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth.
Rajen J Mody, Yi-Mi Wu, Robert J Lonigro, Xuhong Cao, Sameek Roychowdhury, Pankaj Vats, Kevin M Frank, John R Prensner, Irfan Asangani, Nallasivam Palanisamy,[...]. JAMA 2015
Rajen J Mody, Yi-Mi Wu, Robert J Lonigro, Xuhong Cao, Sameek Roychowdhury, Pankaj Vats, Kevin M Frank, John R Prensner, Irfan Asangani, Nallasivam Palanisamy,[...]. JAMA 2015
16
Pharmacogenomics in the curricula of colleges and schools of pharmacy in the United States.
John E Murphy, James S Green, Laura A Adams, Robert B Squire, Grace M Kuo, Alan McKay. Am J Pharm Educ 2010
John E Murphy, James S Green, Laura A Adams, Robert B Squire, Grace M Kuo, Alan McKay. Am J Pharm Educ 2010
16
Clinical delivery of pharmacogenetic testing services: a proposed partnership between genetic counselors and pharmacists.
Rachel Mills, Susanne B Haga. Pharmacogenomics 2013
Rachel Mills, Susanne B Haga. Pharmacogenomics 2013
16
Personalized oncology through integrative high-throughput sequencing: a pilot study.
Sameek Roychowdhury, Matthew K Iyer, Dan R Robinson, Robert J Lonigro, Yi-Mi Wu, Xuhong Cao, Shanker Kalyana-Sundaram, Lee Sam, O Alejandro Balbin, Michael J Quist,[...]. Sci Transl Med 2011
Sameek Roychowdhury, Matthew K Iyer, Dan R Robinson, Robert J Lonigro, Yi-Mi Wu, Xuhong Cao, Shanker Kalyana-Sundaram, Lee Sam, O Alejandro Balbin, Michael J Quist,[...]. Sci Transl Med 2011
16
Tamoxifen Dose Escalation in Patients With Diminished CYP2D6 Activity Normalizes Endoxifen Concentrations Without Increasing Toxicity.
Daniel L Hertz, Allison Deal, Joseph G Ibrahim, Christine M Walko, Karen E Weck, Steven Anderson, Gustav Magrinat, Oludamilola Olajide, Susan Moore, Rachel Raab,[...]. Oncologist 2016
Daniel L Hertz, Allison Deal, Joseph G Ibrahim, Christine M Walko, Karen E Weck, Steven Anderson, Gustav Magrinat, Oludamilola Olajide, Susan Moore, Rachel Raab,[...]. Oncologist 2016
16
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update.
Ursula Amstutz, Linda M Henricks, Steven M Offer, Julia Barbarino, Jan H M Schellens, Jesse J Swen, Teri E Klein, Howard L McLeod, Kelly E Caudle, Robert B Diasio,[...]. Clin Pharmacol Ther 2018
Ursula Amstutz, Linda M Henricks, Steven M Offer, Julia Barbarino, Jan H M Schellens, Jesse J Swen, Teri E Klein, Howard L McLeod, Kelly E Caudle, Robert B Diasio,[...]. Clin Pharmacol Ther 2018
16
The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and Metrics of Pharmacogenetic Implementations Across Diverse Healthcare Systems.
J A Luzum, R E Pakyz, A R Elsey, C E Haidar, J F Peterson, M Whirl-Carrillo, S K Handelman, K Palmer, J M Pulley, M Beller,[...]. Clin Pharmacol Ther 2017
J A Luzum, R E Pakyz, A R Elsey, C E Haidar, J F Peterson, M Whirl-Carrillo, S K Handelman, K Palmer, J M Pulley, M Beller,[...]. Clin Pharmacol Ther 2017
16
A cost effectiveness analysis of thiopurine methyltransferase testing for guiding 6-mercaptopurine dosing in children with acute lymphoblastic leukemia.
Jennifer R Donnan, Wendy J Ungar, Maria Mathews, Rebecca L Hancock-Howard, Proton Rahman. Pediatr Blood Cancer 2011
Jennifer R Donnan, Wendy J Ungar, Maria Mathews, Rebecca L Hancock-Howard, Proton Rahman. Pediatr Blood Cancer 2011
16
Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing: 2013 update.
M V Relling, E E Gardner, W J Sandborn, K Schmiegelow, C-H Pui, S W Yee, C M Stein, M Carrillo, W E Evans, J K Hicks,[...]. Clin Pharmacol Ther 2013
M V Relling, E E Gardner, W J Sandborn, K Schmiegelow, C-H Pui, S W Yee, C M Stein, M Carrillo, W E Evans, J K Hicks,[...]. Clin Pharmacol Ther 2013
16
Novel variants in NUDT15 and thiopurine intolerance in children with acute lymphoblastic leukemia from diverse ancestry.
Takaya Moriyama, Yung-Li Yang, Rina Nishii, Hany Ariffin, Chengcheng Liu, Ting-Nien Lin, Wenjian Yang, Dong-Tsamn Lin, Chih-Hsiang Yu, Shirley Kham,[...]. Blood 2017
Takaya Moriyama, Yung-Li Yang, Rina Nishii, Hany Ariffin, Chengcheng Liu, Ting-Nien Lin, Wenjian Yang, Dong-Tsamn Lin, Chih-Hsiang Yu, Shirley Kham,[...]. Blood 2017
16
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype.
K R Crews, A Gaedigk, H M Dunnenberger, T E Klein, D D Shen, J T Callaghan, E D Kharasch, T C Skaar. Clin Pharmacol Ther 2012
K R Crews, A Gaedigk, H M Dunnenberger, T E Klein, D D Shen, J T Callaghan, E D Kharasch, T C Skaar. Clin Pharmacol Ther 2012
16
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing.
R S Gammal, M H Court, C E Haidar, O F Iwuchukwu, A H Gaur, M Alvarellos, C Guillemette, J L Lennox, M Whirl-Carrillo, S S Brummel,[...]. Clin Pharmacol Ther 2016
R S Gammal, M H Court, C E Haidar, O F Iwuchukwu, A H Gaur, M Alvarellos, C Guillemette, J L Lennox, M Whirl-Carrillo, S S Brummel,[...]. Clin Pharmacol Ther 2016
16
Personalized genomic analyses for cancer mutation discovery and interpretation.
Siân Jones, Valsamo Anagnostou, Karli Lytle, Sonya Parpart-Li, Monica Nesselbush, David R Riley, Manish Shukla, Bryan Chesnick, Maura Kadan, Eniko Papp,[...]. Sci Transl Med 2015
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16
Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA.
Kasmintan A Schrader, Donavan T Cheng, Vijai Joseph, Meera Prasad, Michael Walsh, Ahmet Zehir, Ai Ni, Tinu Thomas, Ryma Benayed, Asad Ashraf,[...]. JAMA Oncol 2016
Kasmintan A Schrader, Donavan T Cheng, Vijai Joseph, Meera Prasad, Michael Walsh, Ahmet Zehir, Ai Ni, Tinu Thomas, Ryma Benayed, Asad Ashraf,[...]. JAMA Oncol 2016
16
Medical decision support systems and therapeutics: The role of autopilots.
R L Woosley, J Whyte, A Mohamadi, K Romero. Clin Pharmacol Ther 2016
R L Woosley, J Whyte, A Mohamadi, K Romero. Clin Pharmacol Ther 2016
9
The value of routine pharmacogenomic screening-Are we there yet? A perspective on the costs and benefits of routine screening-shouldn't everyone have this done?
D L Veenstra. Clin Pharmacol Ther 2016
D L Veenstra. Clin Pharmacol Ther 2016
8
Therapeutic drug monitoring: A patient management tool for precision medicine.
S H Jang, Z Yan, J A Lazor. Clin Pharmacol Ther 2016
S H Jang, Z Yan, J A Lazor. Clin Pharmacol Ther 2016
8
Polyallelic structural variants can provide accurate, highly informative genetic markers focused on diagnosis and therapeutic targets: Accuracy vs. Precision.
A D Roses. Clin Pharmacol Ther 2016
A D Roses. Clin Pharmacol Ther 2016
25
Direct-to-consumer genetic testing: Perspectives on its value in healthcare.
S K Delaney, M F Christman. Clin Pharmacol Ther 2016
S K Delaney, M F Christman. Clin Pharmacol Ther 2016
14
8
Real-world data in the molecular era-finding the reality in the real world.
D J Dickson, J D Pfeifer. Clin Pharmacol Ther 2016
D J Dickson, J D Pfeifer. Clin Pharmacol Ther 2016
12
Precision medicine in the age of big data: The present and future role of large-scale unbiased sequencing in drug discovery and development.
P Vicini, O Fields, E Lai, E D Litwack, A-M Martin, T M Morgan, M A Pacanowski, M Papaluca, O D Perez, M S Ringel,[...]. Clin Pharmacol Ther 2016
P Vicini, O Fields, E Lai, E D Litwack, A-M Martin, T M Morgan, M A Pacanowski, M Papaluca, O D Perez, M S Ringel,[...]. Clin Pharmacol Ther 2016
8
Providing Access to Genomic Variant Knowledge in a Healthcare Setting: A Vision for the ClinGen Electronic Health Records Workgroup.
C L Overby, B Heale, S Aronson, J M Cherry, S Dwight, A Milosavljevic, T Nelson, A Niehaus, M A Weaver, E M Ramos,[...]. Clin Pharmacol Ther 2016
C L Overby, B Heale, S Aronson, J M Cherry, S Dwight, A Milosavljevic, T Nelson, A Niehaus, M A Weaver, E M Ramos,[...]. Clin Pharmacol Ther 2016
10
Adjusting the dose of tamoxifen in patients with early breast cancer and CYP2D6 poor metabolizer phenotype.
Eduardo Martinez de Dueñas, Enrique Ochoa Aranda, Isabel Blancas Lopez-Barajas, Teresa Ferrer Magdalena, Fernando Bandrés Moya, Luis Miguel Chicharro García, José A Gómez Capilla, Mercedes Zafra Ceres, Tomás de Haro, Regina Romero Llorens,[...]. Breast 2014
Eduardo Martinez de Dueñas, Enrique Ochoa Aranda, Isabel Blancas Lopez-Barajas, Teresa Ferrer Magdalena, Fernando Bandrés Moya, Luis Miguel Chicharro García, José A Gómez Capilla, Mercedes Zafra Ceres, Tomás de Haro, Regina Romero Llorens,[...]. Breast 2014
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.