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Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology.
Catharina Steentoft, Sergey Y Vakhrushev, Hiren J Joshi, Yun Kong, Malene B Vester-Christensen, Katrine T-B G Schjoldager, Kirstine Lavrsen, Sally Dabelsteen, Nis B Pedersen, Lara Marcos-Silva,[...]. EMBO J 2013
Catharina Steentoft, Sergey Y Vakhrushev, Hiren J Joshi, Yun Kong, Malene B Vester-Christensen, Katrine T-B G Schjoldager, Kirstine Lavrsen, Sally Dabelsteen, Nis B Pedersen, Lara Marcos-Silva,[...]. EMBO J 2013
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Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family.
Eric P Bennett, Ulla Mandel, Henrik Clausen, Thomas A Gerken, Timothy A Fritz, Lawrence A Tabak. Glycobiology 2012
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Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines.
Catharina Steentoft, Sergey Y Vakhrushev, Malene B Vester-Christensen, Katrine T-B G Schjoldager, Yun Kong, Eric Paul Bennett, Ulla Mandel, Hans Wandall, Steven B Levery, Henrik Clausen. Nat Methods 2011
Catharina Steentoft, Sergey Y Vakhrushev, Malene B Vester-Christensen, Katrine T-B G Schjoldager, Yun Kong, Eric Paul Bennett, Ulla Mandel, Hans Wandall, Steven B Levery, Henrik Clausen. Nat Methods 2011
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Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis.
Yun Kong, Hiren J Joshi, Katrine Ter-Borch Gram Schjoldager, Thomas Daugbjerg Madsen, Thomas A Gerken, Malene B Vester-Christensen, Hans H Wandall, Eric Paul Bennett, Steven B Levery, Sergey Y Vakhrushev,[...]. Glycobiology 2015
Yun Kong, Hiren J Joshi, Katrine Ter-Borch Gram Schjoldager, Thomas Daugbjerg Madsen, Thomas A Gerken, Malene B Vester-Christensen, Hans H Wandall, Eric Paul Bennett, Steven B Levery, Sergey Y Vakhrushev,[...]. Glycobiology 2015
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Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents.
Sumeet A Khetarpal, Katrine T Schjoldager, Christina Christoffersen, Avanthi Raghavan, Andrew C Edmondson, Heiko M Reutter, Bouhouche Ahmed, Reda Ouazzani, Gina M Peloso, Cecilia Vitali,[...]. Cell Metab 2016
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Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation.
Kentaro Kato, Charlotte Jeanneau, Mads Agervig Tarp, Anna Benet-Pagès, Bettina Lorenz-Depiereux, Eric Paul Bennett, Ulla Mandel, Tim M Strom, Henrik Clausen. J Biol Chem 2006
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Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells.
Katrine T-B G Schjoldager, Sergey Y Vakhrushev, Yun Kong, Catharina Steentoft, Aaron S Nudelman, Nis B Pedersen, Hans H Wandall, Ulla Mandel, Eric P Bennett, Steven B Levery,[...]. Proc Natl Acad Sci U S A 2012
Katrine T-B G Schjoldager, Sergey Y Vakhrushev, Yun Kong, Catharina Steentoft, Aaron S Nudelman, Nis B Pedersen, Hans H Wandall, Ulla Mandel, Eric P Bennett, Steven B Levery,[...]. Proc Natl Acad Sci U S A 2012
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Site-specific protein O-glycosylation modulates proprotein processing - deciphering specific functions of the large polypeptide GalNAc-transferase gene family.
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A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation.
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Advances in mass spectrometry driven O-glycoproteomics.
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Mutations in GALNT3, encoding a protein involved in O-linked glycosylation, cause familial tumoral calcinosis.
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Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.
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Mucin-type O-glycosylation is controlled by short- and long-range glycopeptide substrate recognition that varies among members of the polypeptide GalNAc transferase family.
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De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium.
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The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality.
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Emerging paradigms for the initiation of mucin-type protein O-glycosylation by the polypeptide GalNAc transferase family of glycosyltransferases.
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Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines.
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A systematic study of site-specific GalNAc-type O-glycosylation modulating proprotein convertase processing.
Katrine Ter-Borch Gram Schjoldager, Malene B Vester-Christensen, Christoffer K Goth, Thomas Nordahl Petersen, Søren Brunak, Eric P Bennett, Steven B Levery, Henrik Clausen. J Biol Chem 2011
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O-glycosylation modulates proprotein convertase activation of angiopoietin-like protein 3: possible role of polypeptide GalNAc-transferase-2 in regulation of concentrations of plasma lipids.
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Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions.
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A glycogene mutation map for discovery of diseases of glycosylation.
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