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Anne Ml Jansen, Tom van Wezel, Brendy Ewm van den Akker, Marina Ventayol Garcia, Dina Ruano, Carli Mj Tops, Anja Wagner, Tom Gw Letteboer, Encarna B Gómez-García, Peter Devilee, Juul T Wijnen, Frederik J Hes, Hans Morreau. Eur J Hum Genet 2016
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Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas.
Claire Palles, Jean-Baptiste Cazier, Kimberley M Howarth, Enric Domingo, Angela M Jones, Peter Broderick, Zoe Kemp, Sarah L Spain, Estrella Guarino, Israel Salguero,[...]. Nat Genet 2013
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Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer.
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Colon and endometrial cancers with mismatch repair deficiency can arise from somatic, rather than germline, mutations.
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Biallelic MUTYH mutations can mimic Lynch syndrome.
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New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis.
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Clinical problems of colorectal cancer and endometrial cancer cases with unknown cause of tumor mismatch repair deficiency (suspected Lynch syndrome).
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ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes.
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A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.