W Deng, S T Cheung, S W Tsao, X M Wang, A F Y Tiwari. Psychoneuroendocrinology 2016
Times Cited: 33
Times Cited: 33
Times Cited
Times Co-cited
Similarity
Accelerated telomere shortening in response to life stress.
Elissa S Epel, Elizabeth H Blackburn, Jue Lin, Firdaus S Dhabhar, Nancy E Adler, Jason D Morrow, Richard M Cawthon. Proc Natl Acad Sci U S A 2004
Elissa S Epel, Elizabeth H Blackburn, Jue Lin, Firdaus S Dhabhar, Nancy E Adler, Jason D Morrow, Richard M Cawthon. Proc Natl Acad Sci U S A 2004
33
Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging.
Daniel Lindqvist, Elissa S Epel, Synthia H Mellon, Brenda W Penninx, Dóra Révész, Josine E Verhoeven, Victor I Reus, Jue Lin, Laura Mahan, Christina M Hough,[...]. Neurosci Biobehav Rev 2015
Daniel Lindqvist, Elissa S Epel, Synthia H Mellon, Brenda W Penninx, Dóra Révész, Josine E Verhoeven, Victor I Reus, Jue Lin, Laura Mahan, Christina M Hough,[...]. Neurosci Biobehav Rev 2015
27
Resting leukocyte telomerase activity is elevated in major depression and predicts treatment response.
O M Wolkowitz, S H Mellon, E S Epel, J Lin, V I Reus, R Rosser, H Burke, M Compagnone, J C Nelson, F S Dhabhar,[...]. Mol Psychiatry 2012
O M Wolkowitz, S H Mellon, E S Epel, J Lin, V I Reus, R Rosser, H Burke, M Compagnone, J C Nelson, F S Dhabhar,[...]. Mol Psychiatry 2012
24
Telomerase dysregulation in the hippocampus of a rat model of depression: normalization by lithium.
Ya Bin Wei, Lena Backlund, Gregers Wegener, Aleksander A Mathé, Catharina Lavebratt. Int J Neuropsychopharmacol 2015
Ya Bin Wei, Lena Backlund, Gregers Wegener, Aleksander A Mathé, Catharina Lavebratt. Int J Neuropsychopharmacol 2015
24
A meta-analytic review of the effects of mindfulness meditation on telomerase activity.
Nicola S Schutte, John M Malouff. Psychoneuroendocrinology 2014
Nicola S Schutte, John M Malouff. Psychoneuroendocrinology 2014
24
Dynamics of telomerase activity in response to acute psychological stress.
Elissa S Epel, Jue Lin, Firdaus S Dhabhar, Owen M Wolkowitz, E Puterman, Lori Karan, Elizabeth H Blackburn. Brain Behav Immun 2010
Elissa S Epel, Jue Lin, Firdaus S Dhabhar, Owen M Wolkowitz, E Puterman, Lori Karan, Elizabeth H Blackburn. Brain Behav Immun 2010
24
Hippocampal telomerase is involved in the modulation of depressive behaviors.
Qi-Gang Zhou, Yao Hu, Dan-Lian Wu, Li-Juan Zhu, Chen Chen, Xing Jin, Chun-Xia Luo, Hai-Yin Wu, Jing Zhang, Dong-Ya Zhu. J Neurosci 2011
Qi-Gang Zhou, Yao Hu, Dan-Lian Wu, Li-Juan Zhu, Chen Chen, Xing Jin, Chun-Xia Luo, Hai-Yin Wu, Jing Zhang, Dong-Ya Zhu. J Neurosci 2011
21
Major depressive disorder and accelerated cellular aging: results from a large psychiatric cohort study.
J E Verhoeven, D Révész, E S Epel, J Lin, O M Wolkowitz, B W J H Penninx. Mol Psychiatry 2014
J E Verhoeven, D Révész, E S Epel, J Lin, O M Wolkowitz, B W J H Penninx. Mol Psychiatry 2014
21
Effect of comprehensive lifestyle changes on telomerase activity and telomere length in men with biopsy-proven low-risk prostate cancer: 5-year follow-up of a descriptive pilot study.
Dean Ornish, Jue Lin, June M Chan, Elissa Epel, Colleen Kemp, Gerdi Weidner, Ruth Marlin, Steven J Frenda, Mark Jesus M Magbanua, Jennifer Daubenmier,[...]. Lancet Oncol 2013
Dean Ornish, Jue Lin, June M Chan, Elissa Epel, Colleen Kemp, Gerdi Weidner, Ruth Marlin, Steven J Frenda, Mark Jesus M Magbanua, Jennifer Daubenmier,[...]. Lancet Oncol 2013
21
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.
Mariela Jaskelioff, Florian L Muller, Ji-Hye Paik, Emily Thomas, Shan Jiang, Andrew C Adams, Ergun Sahin, Maria Kost-Alimova, Alexei Protopopov, Juan Cadiñanos,[...]. Nature 2011
Mariela Jaskelioff, Florian L Muller, Ji-Hye Paik, Emily Thomas, Shan Jiang, Andrew C Adams, Ergun Sahin, Maria Kost-Alimova, Alexei Protopopov, Juan Cadiñanos,[...]. Nature 2011
18
Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings.
Owen M Wolkowitz, Synthia H Mellon, Elissa S Epel, Jue Lin, Firdaus S Dhabhar, Yali Su, Victor I Reus, Rebecca Rosser, Heather M Burke, Eve Kupferman,[...]. PLoS One 2011
Owen M Wolkowitz, Synthia H Mellon, Elissa S Epel, Jue Lin, Firdaus S Dhabhar, Yali Su, Victor I Reus, Rebecca Rosser, Heather M Burke, Eve Kupferman,[...]. PLoS One 2011
18
Childhood adversities are associated with shorter telomere length at adult age both in individuals with an anxiety disorder and controls.
Laura Kananen, Ida Surakka, Sami Pirkola, Jaana Suvisaari, Jouko Lönnqvist, Leena Peltonen, Samuli Ripatti, Iiris Hovatta. PLoS One 2010
Laura Kananen, Ida Surakka, Sami Pirkola, Jaana Suvisaari, Jouko Lönnqvist, Leena Peltonen, Samuli Ripatti, Iiris Hovatta. PLoS One 2010
18
The Association Between Psychiatric Disorders and Telomere Length: A Meta-Analysis Involving 14,827 Persons.
Sabrina M Darrow, Josine E Verhoeven, Dóra Révész, Daniel Lindqvist, Brenda W J H Penninx, Kevin L Delucchi, Owen M Wolkowitz, Carol A Mathews. Psychosom Med 2016
Sabrina M Darrow, Josine E Verhoeven, Dóra Révész, Daniel Lindqvist, Brenda W J H Penninx, Kevin L Delucchi, Owen M Wolkowitz, Carol A Mathews. Psychosom Med 2016
18
PBMC telomerase activity, but not leukocyte telomere length, correlates with hippocampal volume in major depression.
Owen M Wolkowitz, Synthia H Mellon, Daniel Lindqvist, Elissa S Epel, Elizabeth H Blackburn, Jue Lin, Victor I Reus, Heather Burke, Rebecca Rosser, Laura Mahan,[...]. Psychiatry Res 2015
Owen M Wolkowitz, Synthia H Mellon, Daniel Lindqvist, Elissa S Epel, Elizabeth H Blackburn, Jue Lin, Victor I Reus, Heather Burke, Rebecca Rosser, Laura Mahan,[...]. Psychiatry Res 2015
23
Influence of mindfulness-based stress reduction (MBSR) on telomerase activity in women with breast cancer (BC).
Cecile A Lengacher, Richard R Reich, Kevin E Kip, Michelle Barta, Sophia Ramesar, Carly L Paterson, Manolete S Moscoso, Irina Carranza, Pinky H Budhrani, Seung Joon Kim,[...]. Biol Res Nurs 2014
Cecile A Lengacher, Richard R Reich, Kevin E Kip, Michelle Barta, Sophia Ramesar, Carly L Paterson, Manolete S Moscoso, Irina Carranza, Pinky H Budhrani, Seung Joon Kim,[...]. Biol Res Nurs 2014
18
Physical activity and telomere length: Impact of aging and potential mechanisms of action.
Nicole C Arsenis, Tongjian You, Elisa F Ogawa, Grant M Tinsley, Li Zuo. Oncotarget 2017
Nicole C Arsenis, Tongjian You, Elisa F Ogawa, Grant M Tinsley, Li Zuo. Oncotarget 2017
18
Intensive meditation training, immune cell telomerase activity, and psychological mediators.
Tonya L Jacobs, Elissa S Epel, Jue Lin, Elizabeth H Blackburn, Owen M Wolkowitz, David A Bridwell, Anthony P Zanesco, Stephen R Aichele, Baljinder K Sahdra, Katherine A MacLean,[...]. Psychoneuroendocrinology 2011
Tonya L Jacobs, Elissa S Epel, Jue Lin, Elizabeth H Blackburn, Owen M Wolkowitz, David A Bridwell, Anthony P Zanesco, Stephen R Aichele, Baljinder K Sahdra, Katherine A MacLean,[...]. Psychoneuroendocrinology 2011
18
Long-term lithium treatment in bipolar disorder is associated with longer leukocyte telomeres.
L Martinsson, Y Wei, D Xu, P A Melas, A A Mathé, M Schalling, C Lavebratt, L Backlund. Transl Psychiatry 2013
L Martinsson, Y Wei, D Xu, P A Melas, A A Mathé, M Schalling, C Lavebratt, L Backlund. Transl Psychiatry 2013
15
Ageing and the telomere connection: An intimate relationship with inflammation.
Jingwen Zhang, Grishma Rane, Xiaoyun Dai, Muthu K Shanmugam, Frank Arfuso, Ramar Perumal Samy, Mitchell Kim Peng Lai, Dennis Kappei, Alan Prem Kumar, Gautam Sethi. Ageing Res Rev 2016
Jingwen Zhang, Grishma Rane, Xiaoyun Dai, Muthu K Shanmugam, Frank Arfuso, Ramar Perumal Samy, Mitchell Kim Peng Lai, Dennis Kappei, Alan Prem Kumar, Gautam Sethi. Ageing Res Rev 2016
15
Telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging.
Naomi M Simon, Jordan W Smoller, Kate L McNamara, Richard S Maser, Alyson K Zalta, Mark H Pollack, Andrew A Nierenberg, Maurizio Fava, Kwok-Kin Wong. Biol Psychiatry 2006
Naomi M Simon, Jordan W Smoller, Kate L McNamara, Richard S Maser, Alyson K Zalta, Mark H Pollack, Andrew A Nierenberg, Maurizio Fava, Kwok-Kin Wong. Biol Psychiatry 2006
15
Telomere length and cortisol reactivity in children of depressed mothers.
I H Gotlib, J LeMoult, N L Colich, L C Foland-Ross, J Hallmayer, J Joormann, J Lin, O M Wolkowitz. Mol Psychiatry 2015
I H Gotlib, J LeMoult, N L Colich, L C Foland-Ross, J Hallmayer, J Joormann, J Lin, O M Wolkowitz. Mol Psychiatry 2015
15
Depression, anxiety and telomere length in young adults: evidence from the National Health and Nutrition Examination Survey.
B L Needham, B Mezuk, N Bareis, J Lin, E H Blackburn, E S Epel. Mol Psychiatry 2015
B L Needham, B Mezuk, N Bareis, J Lin, E H Blackburn, E S Epel. Mol Psychiatry 2015
15
Increased telomerase activity and comprehensive lifestyle changes: a pilot study.
Dean Ornish, Jue Lin, Jennifer Daubenmier, Gerdi Weidner, Elissa Epel, Colleen Kemp, Mark Jesus M Magbanua, Ruth Marlin, Loren Yglecias, Peter R Carroll,[...]. Lancet Oncol 2008
Dean Ornish, Jue Lin, Jennifer Daubenmier, Gerdi Weidner, Elissa Epel, Colleen Kemp, Mark Jesus M Magbanua, Ruth Marlin, Loren Yglecias, Peter R Carroll,[...]. Lancet Oncol 2008
15
Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection.
Elizabeth H Blackburn, Elissa S Epel, Jue Lin. Science 2015
Elizabeth H Blackburn, Elissa S Epel, Jue Lin. Science 2015
15
Childhood adversity heightens the impact of later-life caregiving stress on telomere length and inflammation.
Janice K Kiecolt-Glaser, Jean-Philippe Gouin, Nan-Ping Weng, William B Malarkey, David Q Beversdorf, Ronald Glaser. Psychosom Med 2011
Janice K Kiecolt-Glaser, Jean-Philippe Gouin, Nan-Ping Weng, William B Malarkey, David Q Beversdorf, Ronald Glaser. Psychosom Med 2011
12
Of sound mind and body: depression, disease, and accelerated aging.
Owen M Wolkowitz, Victor I Reus, Synthia H Mellon. Dialogues Clin Neurosci 2011
Owen M Wolkowitz, Victor I Reus, Synthia H Mellon. Dialogues Clin Neurosci 2011
12
Changes in stress, eating, and metabolic factors are related to changes in telomerase activity in a randomized mindfulness intervention pilot study.
Jennifer Daubenmier, Jue Lin, Elizabeth Blackburn, Frederick M Hecht, Jean Kristeller, Nicole Maninger, Margaret Kuwata, Peter Bacchetti, Peter J Havel, Elissa Epel. Psychoneuroendocrinology 2012
Jennifer Daubenmier, Jue Lin, Elizabeth Blackburn, Frederick M Hecht, Jean Kristeller, Nicole Maninger, Margaret Kuwata, Peter Bacchetti, Peter J Havel, Elissa Epel. Psychoneuroendocrinology 2012
12
Stress and telomere biology: a lifespan perspective.
Idan Shalev, Sonja Entringer, Pathik D Wadhwa, Owen M Wolkowitz, Eli Puterman, Jue Lin, Elissa S Epel. Psychoneuroendocrinology 2013
Idan Shalev, Sonja Entringer, Pathik D Wadhwa, Owen M Wolkowitz, Eli Puterman, Jue Lin, Elissa S Epel. Psychoneuroendocrinology 2013
12
Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patients.
Amanda K Damjanovic, Yinhua Yang, Ronald Glaser, Janice K Kiecolt-Glaser, Huy Nguyen, Bryon Laskowski, Yixiao Zou, David Q Beversdorf, Nan-ping Weng. J Immunol 2007
Amanda K Damjanovic, Yinhua Yang, Ronald Glaser, Janice K Kiecolt-Glaser, Huy Nguyen, Bryon Laskowski, Yixiao Zou, David Q Beversdorf, Nan-ping Weng. J Immunol 2007
12
Depression and telomere length: A meta-analysis.
Kathryn K Ridout, Samuel J Ridout, Lawrence H Price, Srijan Sen, Audrey R Tyrka. J Affect Disord 2016
Kathryn K Ridout, Samuel J Ridout, Lawrence H Price, Srijan Sen, Audrey R Tyrka. J Affect Disord 2016
12
Shortened telomere length in patients with depression: A meta-analytic study.
Pao-Yen Lin, Yu-Chi Huang, Chi-Fa Hung. J Psychiatr Res 2016
Pao-Yen Lin, Yu-Chi Huang, Chi-Fa Hung. J Psychiatr Res 2016
12
Cell aging in relation to stress arousal and cardiovascular disease risk factors.
Elissa S Epel, Jue Lin, Frank H Wilhelm, Owen M Wolkowitz, Richard Cawthon, Nancy E Adler, Christyn Dolbier, Wendy B Mendes, Elizabeth H Blackburn. Psychoneuroendocrinology 2006
Elissa S Epel, Jue Lin, Frank H Wilhelm, Owen M Wolkowitz, Richard Cawthon, Nancy E Adler, Christyn Dolbier, Wendy B Mendes, Elizabeth H Blackburn. Psychoneuroendocrinology 2006
12
Does cellular aging relate to patterns of allostasis? An examination of basal and stress reactive HPA axis activity and telomere length.
A Janet Tomiyama, Aoife O'Donovan, Jue Lin, Eli Puterman, Alanie Lazaro, Jessica Chan, Firdaus S Dhabhar, Owen Wolkowitz, Clemens Kirschbaum, Elizabeth Blackburn,[...]. Physiol Behav 2012
A Janet Tomiyama, Aoife O'Donovan, Jue Lin, Eli Puterman, Alanie Lazaro, Jessica Chan, Firdaus S Dhabhar, Owen Wolkowitz, Clemens Kirschbaum, Elizabeth Blackburn,[...]. Physiol Behav 2012
12
Telomere length of patients with major depression is shortened but independent from therapy and severity of the disease.
Nils Hartmann, Marina Boehner, Franziska Groenen, Roland Kalb. Depress Anxiety 2010
Nils Hartmann, Marina Boehner, Franziska Groenen, Roland Kalb. Depress Anxiety 2010
12
Major depressive disorder mediates accelerated aging in rats subjected to chronic mild stress.
Xiaoxian Xie, Yangyang Chen, Lingyan Ma, Qichen Shen, Liangfeng Huang, Binggong Zhao, Tao Wu, Zhengwei Fu. Behav Brain Res 2017
Xiaoxian Xie, Yangyang Chen, Lingyan Ma, Qichen Shen, Liangfeng Huang, Binggong Zhao, Tao Wu, Zhengwei Fu. Behav Brain Res 2017
18
Mindfulness-based cancer recovery and supportive-expressive therapy maintain telomere length relative to controls in distressed breast cancer survivors.
Linda E Carlson, Tara L Beattie, Janine Giese-Davis, Peter Faris, Rie Tamagawa, Laura J Fick, Erin S Degelman, Michael Speca. Cancer 2015
Linda E Carlson, Tara L Beattie, Janine Giese-Davis, Peter Faris, Rie Tamagawa, Laura J Fick, Erin S Degelman, Michael Speca. Cancer 2015
12
Identification of seven loci affecting mean telomere length and their association with disease.
Veryan Codd, Christopher P Nelson, Eva Albrecht, Massimo Mangino, Joris Deelen, Jessica L Buxton, Jouke Jan Hottenga, Krista Fischer, Tõnu Esko, Ida Surakka,[...]. Nat Genet 2013
Veryan Codd, Christopher P Nelson, Eva Albrecht, Massimo Mangino, Joris Deelen, Jessica L Buxton, Jouke Jan Hottenga, Krista Fischer, Tõnu Esko, Ida Surakka,[...]. Nat Genet 2013
12
Shortened telomere length in white matter oligodendrocytes in major depression: potential role of oxidative stress.
Attila Szebeni, Katalin Szebeni, Timothy DiPeri, Michelle J Chandley, Jessica D Crawford, Craig A Stockmeier, Gregory A Ordway. Int J Neuropsychopharmacol 2014
Attila Szebeni, Katalin Szebeni, Timothy DiPeri, Michelle J Chandley, Jessica D Crawford, Craig A Stockmeier, Gregory A Ordway. Int J Neuropsychopharmacol 2014
12
Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder.
I Shalev, T E Moffitt, A W Braithwaite, A Danese, N I Fleming, S Goldman-Mellor, H L Harrington, R M Houts, S Israel, R Poulton,[...]. Mol Psychiatry 2014
I Shalev, T E Moffitt, A W Braithwaite, A Danese, N I Fleming, S Goldman-Mellor, H L Harrington, R M Houts, S Israel, R Poulton,[...]. Mol Psychiatry 2014
12
A randomized controlled trial of qigong exercise on fatigue symptoms, functioning, and telomerase activity in persons with chronic fatigue or chronic fatigue syndrome.
Rainbow T H Ho, Jessie S M Chan, Chong-Wen Wang, Benson W M Lau, Kwok Fai So, Li Ping Yuen, Jonathan S T Sham, Cecilia L W Chan. Ann Behav Med 2012
Rainbow T H Ho, Jessie S M Chan, Chong-Wen Wang, Benson W M Lau, Kwok Fai So, Li Ping Yuen, Jonathan S T Sham, Cecilia L W Chan. Ann Behav Med 2012
12
Aerobic exercise lengthens telomeres and reduces stress in family caregivers: A randomized controlled trial - Curt Richter Award Paper 2018.
Eli Puterman, Jordan Weiss, Jue Lin, Samantha Schilf, Aaron L Slusher, Kirsten L Johansen, Elissa S Epel. Psychoneuroendocrinology 2018
Eli Puterman, Jordan Weiss, Jue Lin, Samantha Schilf, Aaron L Slusher, Kirsten L Johansen, Elissa S Epel. Psychoneuroendocrinology 2018
12
Blood cell telomere length is a dynamic feature.
Ulrika Svenson, Katarina Nordfjäll, Duncan Baird, Laureline Roger, Pia Osterman, Mai-Lis Hellenius, Göran Roos. PLoS One 2011
Ulrika Svenson, Katarina Nordfjäll, Duncan Baird, Laureline Roger, Pia Osterman, Mai-Lis Hellenius, Göran Roos. PLoS One 2011
12
Gender and telomere length: systematic review and meta-analysis.
Michael Gardner, David Bann, Laura Wiley, Rachel Cooper, Rebecca Hardy, Dorothea Nitsch, Carmen Martin-Ruiz, Paul Shiels, Avan Aihie Sayer, Michelangela Barbieri,[...]. Exp Gerontol 2014
Michael Gardner, David Bann, Laura Wiley, Rachel Cooper, Rebecca Hardy, Dorothea Nitsch, Carmen Martin-Ruiz, Paul Shiels, Avan Aihie Sayer, Michelangela Barbieri,[...]. Exp Gerontol 2014
12
The power of exercise: buffering the effect of chronic stress on telomere length.
Eli Puterman, Jue Lin, Elizabeth Blackburn, Aoife O'Donovan, Nancy Adler, Elissa Epel. PLoS One 2010
Eli Puterman, Jue Lin, Elizabeth Blackburn, Aoife O'Donovan, Nancy Adler, Elissa Epel. PLoS One 2010
12
Stress and immunosenescence: The role of telomerase.
Karin de Punder, Christine Heim, Pathik D Wadhwa, Sonja Entringer. Psychoneuroendocrinology 2019
Karin de Punder, Christine Heim, Pathik D Wadhwa, Sonja Entringer. Psychoneuroendocrinology 2019
18
Systematic review of the association between chronic social stress and telomere length: A life course perspective.
Bruna Silva Oliveira, Maria Victoria Zunzunegui, Jacklyn Quinlan, Hassan Fahmi, Mai Thanh Tu, Ricardo Oliveira Guerra. Ageing Res Rev 2016
Bruna Silva Oliveira, Maria Victoria Zunzunegui, Jacklyn Quinlan, Hassan Fahmi, Mai Thanh Tu, Ricardo Oliveira Guerra. Ageing Res Rev 2016
9
Telomere length and telomerase in a well-characterized sample of individuals with major depressive disorder compared to controls.
Naomi M Simon, Zandra E Walton, Eric Bui, Jennifer Prescott, Elizabeth Hoge, Aparna Keshaviah, Noah Schwarz, Taylor Dryman, Rebecca A Ojserkis, Benjamin Kovachy,[...]. Psychoneuroendocrinology 2015
Naomi M Simon, Zandra E Walton, Eric Bui, Jennifer Prescott, Elizabeth Hoge, Aparna Keshaviah, Noah Schwarz, Taylor Dryman, Rebecca A Ojserkis, Benjamin Kovachy,[...]. Psychoneuroendocrinology 2015
9
Telomerase activation as a possible mechanism of action for psychopharmacological interventions.
Francesco S Bersani, Daniel Lindqvist, Synthia H Mellon, Brenda W J H Penninx, Josine E Verhoeven, Dóra Révész, Victor I Reus, Owen M Wolkowitz. Drug Discov Today 2015
Francesco S Bersani, Daniel Lindqvist, Synthia H Mellon, Brenda W J H Penninx, Josine E Verhoeven, Dóra Révész, Victor I Reus, Owen M Wolkowitz. Drug Discov Today 2015
10
From stress to inflammation and major depressive disorder: a social signal transduction theory of depression.
George M Slavich, Michael R Irwin. Psychol Bull 2014
George M Slavich, Michael R Irwin. Psychol Bull 2014
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.