A citation-based method for searching scientific literature

Andras Perl. Nat Rev Rheumatol 2016
Times Cited: 152







List of co-cited articles
656 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.
Zhi-Wei Lai, Ryan Kelly, Thomas Winans, Ivan Marchena, Ashwini Shadakshari, Julie Yu, Maha Dawood, Ricardo Garcia, Hajra Tily, Lisa Francis,[...]. Lancet 2018
152
31

Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus.
David Fernandez, Eduardo Bonilla, Naureen Mirza, Brian Niland, Andras Perl. Arthritis Rheum 2006
200
21

N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial.
Zhi-Wei Lai, Robert Hanczko, Eduardo Bonilla, Tiffany N Caza, Brandon Clair, Adam Bartos, Gabriella Miklossy, John Jimah, Edward Doherty, Hajra Tily,[...]. Arthritis Rheum 2012
200
17


Systemic lupus erythematosus.
George C Tsokos. N Engl J Med 2011
15


Activation of the Mechanistic Target of Rapamycin in SLE: Explosion of Evidence in the Last Five Years.
Zachary Oaks, Thomas Winans, Nick Huang, Katalin Banki, Andras Perl. Curr Rheumatol Rep 2016
42
33

Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus.
Zhi-Wei Lai, Rebecca Borsuk, Ashwini Shadakshari, Jianghong Yu, Maha Dawood, Ricardo Garcia, Lisa Francis, Hajra Tily, Adam Bartos, Stephen V Faraone,[...]. J Immunol 2013
76
17


Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus-Prone Mice.
Zachary Oaks, Thomas Winans, Tiffany Caza, David Fernandez, Yuxin Liu, Steve K Landas, Katalin Banki, Andras Perl. Arthritis Rheumatol 2016
52
25

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.
Lewis Z Shi, Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R Green, Hongbo Chi. J Exp Med 2011
990
13

mTOR Signaling in Growth, Metabolism, and Disease.
Robert A Saxton, David M Sabatini. Cell 2017
13

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Greg M Delgoffe, Kristen N Pollizzi, Adam T Waickman, Emily Heikamp, David J Meyers, Maureen R Horton, Bo Xiao, Paul F Worley, Jonathan D Powell. Nat Immunol 2011
715
12


Normalization of CD4+ T cell metabolism reverses lupus.
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Daniel J Perry, Howard Seay, Byron P Croker, Eric S Sobel, Todd M Brusko, Laurence Morel. Sci Transl Med 2015
293
12

Inhibition of the mTORC pathway in the antiphospholipid syndrome.
Guillaume Canaud, Frank Bienaimé, Fanny Tabarin, Guillaume Bataillon, Danielle Seilhean, Laure-Hélène Noël, Marie-Agnès Dragon-Durey, Renaud Snanoudj, Gérard Friedlander, Lise Halbwachs-Mecarelli,[...]. N Engl J Med 2014
169
9

Immunometabolism in systemic lupus erythematosus.
Laurence Morel. Nat Rev Rheumatol 2017
99
9

The 1982 revised criteria for the classification of systemic lupus erythematosus.
E M Tan, A S Cohen, J F Fries, A T Masi, D J McShane, N F Rothfield, J G Schaller, N Talal, R J Winchester. Arthritis Rheum 1982
8

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.
Luciana Berod, Christin Friedrich, Amrita Nandan, Jenny Freitag, Stefanie Hagemann, Kirsten Harmrolfs, Aline Sandouk, Christina Hesse, Carla N Castro, Heike Bähre,[...]. Nat Med 2014
417
8

Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.
Valerie A Gerriets, Rigel J Kishton, Amanda G Nichols, Andrew N Macintyre, Makoto Inoue, Olga Ilkayeva, Peter S Winter, Xiaojing Liu, Bhavana Priyadharshini, Marta E Slawinska,[...]. J Clin Invest 2015
351
8

The pathogenesis of rheumatoid arthritis.
Iain B McInnes, Georg Schett. N Engl J Med 2011
8

mTOR signaling in growth control and disease.
Mathieu Laplante, David M Sabatini. Cell 2012
8

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.
Greg M Delgoffe, Thomas P Kole, Yan Zheng, Paul E Zarek, Krystal L Matthews, Bo Xiao, Paul F Worley, Sara C Kozma, Jonathan D Powell. Immunity 2009
791
8

Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus.
Peter Gergely, Craig Grossman, Brian Niland, Ferenc Puskas, Hom Neupane, Fatme Allam, Katalin Banki, Paul E Phillips, Andras Perl. Arthritis Rheum 2002
203
8

mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.
Hu Zeng, Kai Yang, Caryn Cloer, Geoffrey Neale, Peter Vogel, Hongbo Chi. Nature 2013
463
8

Metabolism as a Target for Modulation in Autoimmune Diseases.
Nick Huang, Andras Perl. Trends Immunol 2018
51
15

Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.
David R Fernandez, Tiffany Telarico, Eduardo Bonilla, Qing Li, Sanjay Banerjee, Frank A Middleton, Paul E Phillips, Mary K Crow, Stefanie Oess, Werner Muller-Esterl,[...]. J Immunol 2009
151
7

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
Ryan D Michalek, Valerie A Gerriets, Sarah R Jacobs, Andrew N Macintyre, Nancie J MacIver, Emily F Mason, Sarah A Sullivan, Amanda G Nichols, Jeffrey C Rathmell. J Immunol 2011
7

Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis.
Daniel Cejka, Silvia Hayer, Birgit Niederreiter, Wolfgang Sieghart, Thorsten Fuereder, Jochen Zwerina, Georg Schett. Arthritis Rheum 2010
112
7


A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjögren's syndrome.
Mihir Shah, Maria C Edman, Srikanth R Janga, Pu Shi, Jugal Dhandhukia, Siyu Liu, Stan G Louie, Kathleen Rodgers, J Andrew Mackay, Sarah F Hamm-Alvarez. J Control Release 2013
67
10

Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin.
Andras Perl, Robert Hanczko, Zhi-Wei Lai, Zachary Oaks, Ryan Kelly, Rebecca Borsuk, John M Asara, Paul E Phillips. Metabolomics 2015
66
10


Everolimus in patients with rheumatoid arthritis receiving concomitant methotrexate: a 3-month, double-blind, randomised, placebo-controlled, parallel-group, proof-of-concept study.
G A W Bruyn, G Tate, F Caeiro, J Maldonado-Cocco, R Westhovens, H Tannenbaum, M Bell, O Forre, O Bjorneboe, P P Tak,[...]. Ann Rheum Dis 2008
56
12

Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus.
Takayuki Katsuyama, George C Tsokos, Vaishali R Moulton. Front Immunol 2018
75
9

Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective.
Vaishali R Moulton, Abel Suarez-Fueyo, Esra Meidan, Hao Li, Masayuki Mizui, George C Tsokos. Trends Mol Med 2017
139
7

Clinical Experience of Sirolimus Regarding Efficacy and Safety in Systemic Lupus Erythematosus.
Per Eriksson, Philip Wallin, Christopher Sjöwall. Front Pharmacol 2019
20
35

mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation.
Hu Zeng, Sivan Cohen, Cliff Guy, Sharad Shrestha, Geoffrey Neale, Scott A Brown, Caryn Cloer, Rigel J Kishton, Xia Gao, Ben Youngblood,[...]. Immunity 2016
173
6

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.
Tiffany N Caza, David R Fernandez, Gergely Talaber, Zachary Oaks, Mark Haas, Michael P Madaio, Zhi-Wei Lai, Gabriella Miklossy, Ram R Singh, Dmitriy M Chudakov,[...]. Ann Rheum Dis 2014
77
7

Fueling immunity: insights into metabolism and lymphocyte function.
Erika L Pearce, Maya C Poffenberger, Chih-Hao Chang, Russell G Jones. Science 2013
677
6

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation.
Linda V Sinclair, Julia Rolf, Elizabeth Emslie, Yun-Bo Shi, Peter M Taylor, Doreen A Cantrell. Nat Immunol 2013
449
6


Longterm Data on Sirolimus Treatment in Patients with Lupus Nephritis.
Desmond Y H Yap, Colin Tang, Gary C W Chan, Lorraine P Y Kwan, Maggie K M Ma, Maggie M Y Mok, Tak Mao Chan. J Rheumatol 2018
23
26


Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells.
Zhen Yang, Hiroshi Fujii, Shalini V Mohan, Jorg J Goronzy, Cornelia M Weyand. J Exp Med 2013
184
6

Restoring oxidant signaling suppresses proarthritogenic T cell effector functions in rheumatoid arthritis.
Zhen Yang, Yi Shen, Hisashi Oishi, Eric L Matteson, Lu Tian, Jörg J Goronzy, Cornelia M Weyand. Sci Transl Med 2016
122
6

Metformin attenuates experimental autoimmune arthritis through reciprocal regulation of Th17/Treg balance and osteoclastogenesis.
Hye-Jin Son, Jennifer Lee, Seon-Yeong Lee, Eun-Kyung Kim, Min-Jung Park, Kyoung-Woon Kim, Sung-Hwan Park, Mi-La Cho. Mediators Inflamm 2014
119
6

New insights into the immunopathogenesis of systemic lupus erythematosus.
George C Tsokos, Mindy S Lo, Patricia Costa Reis, Kathleen E Sullivan. Nat Rev Rheumatol 2016
402
6

Rapamycin attenuates the severity of established nephritis in lupus-prone NZB/W F1 mice.
Sing Leung Lui, Ryan Tsang, Kwok Wah Chan, Florence Zhang, Sidney Tam, Susan Yung, Tak Mao Chan. Nephrol Dial Transplant 2008
56
10

Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1.
Eric V Dang, Joseph Barbi, Huang-Yu Yang, Dilini Jinasena, Hong Yu, Ying Zheng, Zachary Bordman, Juan Fu, Young Kim, Hung-Rong Yen,[...]. Cell 2011
892
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.