A citation-based method for searching scientific literature

Mariana Conceição, Liliana Mendonça, Clévio Nóbrega, Célia Gomes, Pedro Costa, Hirokazu Hirai, João Nuno Moreira, Maria C Lima, N Manjunath, Luís Pereira de Almeida. Biomaterials 2016
Times Cited: 49







List of co-cited articles
943 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease.
Sandro Alves, Isabel Nascimento-Ferreira, Gwennaëlle Auregan, Raymonde Hassig, Noëlle Dufour, Emmanuel Brouillet, Maria C Pedroso de Lima, Philippe Hantraye, Luís Pereira de Almeida, Nicole Déglon. PLoS One 2008
106
30

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes.
Lydia Alvarez-Erviti, Yiqi Seow, Haifang Yin, Corinne Betts, Samira Lakhal, Matthew J A Wood. Nat Biotechnol 2011
28

Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice.
Clévio Nóbrega, Isabel Nascimento-Ferreira, Isabel Onofre, David Albuquerque, Hirokazu Hirai, Nicole Déglon, Luís Pereira de Almeida. PLoS One 2013
78
26

Evaluation of Antisense Oligonucleotides Targeting ATXN3 in SCA3 Mouse Models.
Lauren R Moore, Gautam Rajpal, Ian T Dillingham, Maya Qutob, Kate G Blumenstein, Danielle Gattis, Gene Hung, Holly B Kordasiewicz, Henry L Paulson, Hayley S McLoughlin. Mol Ther Nucleic Acids 2017
63
26

Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease.
Isabel Nascimento-Ferreira, Tiago Santos-Ferreira, Lígia Sousa-Ferreira, Gwennaëlle Auregan, Isabel Onofre, Sandro Alves, Noëlle Dufour, Veronica F Colomer Gould, Arnulf Koeppen, Nicole Déglon,[...]. Brain 2011
124
24

Toward RNAi therapy for the polyglutamine disease Machado-Joseph disease.
Maria do Carmo Costa, Katiuska Luna-Cancalon, Svetlana Fischer, Naila S Ashraf, Michelle Ouyang, Rahil M Dharia, Lucas Martin-Fishman, Yemen Yang, Vikram G Shakkottai, Beverly L Davidson,[...]. Mol Ther 2013
66
24

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease.
Ana T Simões, Nélio Gonçalves, Arnulf Koeppen, Nicole Déglon, Sebastian Kügler, Carlos Bandeira Duarte, Luís Pereira de Almeida. Brain 2012
79
22

Silencing ataxin-3 mitigates degeneration in a rat model of Machado-Joseph disease: no role for wild-type ataxin-3?
Sandro Alves, Isabel Nascimento-Ferreira, Noëlle Dufour, Raymonde Hassig, Gwennaëlle Auregan, Clévio Nóbrega, Emmanuel Brouillet, Philippe Hantraye, Maria C Pedroso de Lima, Nicole Déglon,[...]. Hum Mol Genet 2010
74
22

Ataxin-3 protein modification as a treatment strategy for spinocerebellar ataxia type 3: removal of the CAG containing exon.
Melvin M Evers, Hoang-Dai Tran, Ioannis Zalachoras, Barry A Pepers, Onno C Meijer, Johan T den Dunnen, Gert-Jan B van Ommen, Annemieke Aartsma-Rus, Willeke M C van Roon-Mom. Neurobiol Dis 2013
46
23

Silencing mutant ATXN3 expression resolves molecular phenotypes in SCA3 transgenic mice.
Edgardo Rodríguez-Lebrón, Maria do Carmo Costa, Katiuska Luna-Cancalon, Therese M Peron, Svetlana Fischer, Ryan L Boudreau, Beverly L Davidson, Henry L Paulson. Mol Ther 2013
70
22

RNA interference mitigates motor and neuropathological deficits in a cerebellar mouse model of Machado-Joseph disease.
Clévio Nóbrega, Isabel Nascimento-Ferreira, Isabel Onofre, David Albuquerque, Nicole Déglon, Luís Pereira de Almeida. PLoS One 2014
24
41

Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice.
Liliana S Mendonça, Clévio Nóbrega, Hirokazu Hirai, Brian K Kaspar, Luís Pereira de Almeida. Brain 2015
52
18

Transvascular delivery of small interfering RNA to the central nervous system.
Priti Kumar, Haoquan Wu, Jodi L McBride, Kyeong-Eun Jung, Moon Hee Kim, Beverly L Davidson, Sang Kyung Lee, Premlata Shankar, N Manjunath. Nature 2007
804
18

Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.
Joana Duarte-Neves, Nélio Gonçalves, Janete Cunha-Santos, Ana Teresa Simões, Wilfred F A den Dunnen, Hirokazu Hirai, Sebastian Kügler, Cláudia Cavadas, Luís Pereira de Almeida. Hum Mol Genet 2015
35
25

Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway.
Janete Cunha-Santos, Joana Duarte-Neves, Vitor Carmona, Leonard Guarente, Luís Pereira de Almeida, Cláudia Cavadas. Nat Commun 2016
53
18

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1.
Y Kawaguchi, T Okamoto, M Taniwaki, M Aizawa, M Inoue, S Katayama, H Kawakami, S Nakamura, M Nishimura, I Akiguchi. Nat Genet 1994
18

Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease.
Vitor Carmona, Janete Cunha-Santos, Isabel Onofre, Ana Teresa Simões, Udaya Vijayakumar, Beverly L Davidson, Luís Pereira de Almeida. Mol Ther 2017
24
37

Antisense Oligonucleotide-Mediated Removal of the Polyglutamine Repeat in Spinocerebellar Ataxia Type 3 Mice.
Lodewijk J A Toonen, Frank Rigo, Haico van Attikum, Willeke M C van Roon-Mom. Mol Ther Nucleic Acids 2017
52
18

Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease.
Isabel Nascimento-Ferreira, Clévio Nóbrega, Ana Vasconcelos-Ferreira, Isabel Onofre, David Albuquerque, Célia Aveleira, Hirokazu Hirai, Nicole Déglon, Luís Pereira de Almeida. Brain 2013
68
18

Caffeine and adenosine A(2A) receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado-Joseph disease.
Nélio Gonçalves, Ana T Simões, Rodrigo A Cunha, Luís Pereira de Almeida. Ann Neurol 2013
50
16

Antisense oligonucleotide-mediated exon skipping as a strategy to reduce proteolytic cleavage of ataxin-3.
Lodewijk J A Toonen, Iris Schmidt, Martijn S Luijsterburg, Haico van Attikum, Willeke M C van Roon-Mom. Sci Rep 2016
23
34

RNAi-mediated gene silencing in non-human primates.
Tracy S Zimmermann, Amy C H Lee, Akin Akinc, Birgit Bramlage, David Bumcrot, Matthew N Fedoruk, Jens Harborth, James A Heyes, Lloyd B Jeffs, Matthias John,[...]. Nature 2006
977
16

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.
Haibin Xia, Qinwen Mao, Steven L Eliason, Scott Q Harper, Inês H Martins, Harry T Orr, Henry L Paulson, Linda Yang, Robert M Kotin, Beverly L Davidson. Nat Med 2004
485
14

A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration.
Daniel Goti, Scott M Katzen, Jesse Mez, Noam Kurtis, Jennifer Kiluk, Lea Ben-Haïem, Nancy A Jenkins, Neal G Copeland, Akira Kakizuka, Alan H Sharp,[...]. J Neurosci 2004
141
14

Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence.
Ulrike Bichelmeier, Thorsten Schmidt, Jeannette Hübener, Jana Boy, Lukas Rüttiger, Karina Häbig, Sven Poths, Michael Bonin, Marlies Knipper, Werner J Schmidt,[...]. J Neurosci 2007
132
14

Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease.
Clévio Nóbrega, Sara Carmo-Silva, David Albuquerque, Ana Vasconcelos-Ferreira, Udaya-Geetha Vijayakumar, Liliana Mendonça, Hirokazu Hirai, Luís Pereira de Almeida. Brain 2015
23
30

Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3.
Xi Chen, Tie-Shan Tang, Huiping Tu, Omar Nelson, Mark Pook, Robert Hammer, Nobuyuki Nukina, Ilya Bezprozvanny. J Neurosci 2008
152
14

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease.
Philipp Koch, Peter Breuer, Michael Peitz, Johannes Jungverdorben, Jaideep Kesavan, Daniel Poppe, Jonas Doerr, Julia Ladewig, Jerome Mertens, Thomas Tüting,[...]. Nature 2011
225
14

Chronic treatment with 17-DMAG improves balance and coordination in a new mouse model of Machado-Joseph disease.
Anabela Silva-Fernandes, Sara Duarte-Silva, Andreia Neves-Carvalho, Marina Amorim, Carina Soares-Cunha, Pedro Oliveira, Kenneth Thirstrup, Andreia Teixeira-Castro, Patrícia Maciel. Neurotherapeutics 2014
64
14

Machado-Joseph disease/spinocerebellar ataxia type 3: lessons from disease pathogenesis and clues into therapy.
Carlos A Matos, Luís Pereira de Almeida, Clévio Nóbrega. J Neurochem 2019
39
17

MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma.
Pedro M Costa, Ana L Cardoso, Carlos Custódia, Pedro Cunha, Luís Pereira de Almeida, Maria C Pedroso de Lima. J Control Release 2015
107
12

Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice.
J Mark Cooper, P B Oscar Wiklander, Joel Z Nordin, Raya Al-Shawi, Matthew J Wood, Mansi Vithlani, Anthony H V Schapira, J Paul Simons, Samir El-Andaloussi, Lydia Alvarez-Erviti. Mov Disord 2014
226
12

Permanent inactivation of Huntington's disease mutation by personalized allele-specific CRISPR/Cas9.
Jun Wan Shin, Kyung-Hee Kim, Michael J Chao, Ranjit S Atwal, Tammy Gillis, Marcy E MacDonald, James F Gusella, Jong-Min Lee. Hum Mol Genet 2016
118
12

Allele-specific silencing of mutant Ataxin-7 in SCA7 patient-derived fibroblasts.
Janine Scholefield, Lauren Watson, Danielle Smith, Jacquie Greenberg, Matthew J A Wood. Eur J Hum Genet 2014
22
27

miR-25 alleviates polyQ-mediated cytotoxicity by silencing ATXN3.
Fengzhen Huang, Li Zhang, Zhe Long, Zhao Chen, Xuan Hou, Chunrong Wang, Huirong Peng, Junling Wang, Jiada Li, Ranhui Duan,[...]. FEBS Lett 2014
27
22

An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron.
Yu Miyazaki, Xiaofei Du, Shin-Ichi Muramatsu, Christopher M Gomez. Sci Transl Med 2016
35
17

Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment.
Pedro M Costa, Ana L Cardoso, Liliana S Mendonça, Angelo Serani, Carlos Custódia, Mariana Conceição, Sérgio Simões, João N Moreira, Luís Pereira de Almeida, Maria C Pedroso de Lima. Mol Ther Nucleic Acids 2013
60
12

An isoform of ataxin-3 accumulates in the nucleus of neuronal cells in affected brain regions of SCA3 patients.
T Schmidt, G B Landwehrmeyer, I Schmitt, Y Trottier, G Auburger, F Laccone, T Klockgether, M Völpel, J T Epplen, L Schöls,[...]. Brain Pathol 1998
156
12

Ataxin-3 protein and RNA toxicity in spinocerebellar ataxia type 3: current insights and emerging therapeutic strategies.
Melvin M Evers, Lodewijk J A Toonen, Willeke M C van Roon-Mom. Mol Neurobiol 2014
48
12

Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7.
Udo Rüb, Ludger Schöls, Henry Paulson, Georg Auburger, Pawel Kermer, Joanna C Jen, Kay Seidel, Horst-Werner Korf, Thomas Deller. Prog Neurobiol 2013
172
12

Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination.
Ina Schmitt, Marion Linden, Hassan Khazneh, Bernd O Evert, Peter Breuer, Thomas Klockgether, Ullrich Wuellner. Biochem Biophys Res Commun 2007
99
12

Safety and efficacy of RNAi therapy for transthyretin amyloidosis.
Teresa Coelho, David Adams, Ana Silva, Pierre Lozeron, Philip N Hawkins, Timothy Mant, Javier Perez, Joseph Chiesa, Steve Warrington, Elizabeth Tranter,[...]. N Engl J Med 2013
587
12

Calpain Inhibition Is Protective in Machado-Joseph Disease Zebrafish Due to Induction of Autophagy.
Maxinne Watchon, Kristy C Yuan, Nick Mackovski, Adam J Svahn, Nicholas J Cole, Claire Goldsbury, Silke Rinkwitz, Thomas S Becker, Garth A Nicholson, Angela S Laird. J Neurosci 2017
34
17

Calpain inhibition is sufficient to suppress aggregation of polyglutamine-expanded ataxin-3.
Annette Haacke, F Ulrich Hartl, Peter Breuer. J Biol Chem 2007
70
12

Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3.
Fiona M Menzies, Jeannette Huebener, Maurizio Renna, Michael Bonin, Olaf Riess, David C Rubinsztein. Brain 2010
179
12

From pathways to targets: understanding the mechanisms behind polyglutamine disease.
Jonasz Jeremiasz Weber, Anna Sergeevna Sowa, Tina Binder, Jeannette Hübener. Biomed Res Int 2014
34
17

Polyglutamine spinocerebellar ataxias - from genes to potential treatments.
Henry L Paulson, Vikram G Shakkottai, H Brent Clark, Harry T Orr. Nat Rev Neurosci 2017
131
12

Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease.
Andreia Teixeira-Castro, Ana Jalles, Sofia Esteves, Soosung Kang, Liliana da Silva Santos, Anabela Silva-Fernandes, Mário F Neto, Renée M Brielmann, Carlos Bessa, Sara Duarte-Silva,[...]. Brain 2015
48
12

Autosomal dominant cerebellar ataxias: clinical features, genetics, and pathogenesis.
Ludger Schöls, Peter Bauer, Thorsten Schmidt, Thorsten Schulte, Olaf Riess. Lancet Neurol 2004
650
12

T1-11 and JMF1907 ameliorate polyglutamine-expanded ataxin-3-induced neurodegeneration, transcriptional dysregulation and ataxic symptom in the SCA3 transgenic mouse.
An-Hsun Chou, Ying-Ling Chen, Ching-Chi Chiu, Shin-Je Yuan, Yi-Hsin Weng, Tu-Hsueh Yeh, Yun-Lian Lin, Jim-Min Fang, Hung-Li Wang. Neuropharmacology 2015
18
33


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.