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CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy.
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Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape.
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A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.
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4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors.
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Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting.
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T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells.
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Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition.
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CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients.
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Tumor Antigen Escape from CAR T-cell Therapy.
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Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia.
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A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells.
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IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor.
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Switchable control over in vivo CAR T expansion, B cell depletion, and induction of memory.
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Chimeric antigen receptor T Cells with dissociated signaling domains exhibit focused antitumor activity with reduced potential for toxicity in vivo.
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Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia.
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Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo.
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Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells.
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Dominant-Negative TGF-β Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication.
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Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia.
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Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes.
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IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors in vivo.
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A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.