A citation-based method for searching scientific literature

S J Padayatty, M Levine. Oral Dis 2016
Times Cited: 201







List of co-cited articles
767 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Vitamin C pharmacokinetics: implications for oral and intravenous use.
Sebastian J Padayatty, He Sun, Yaohui Wang, Hugh D Riordan, Stephen M Hewitt, Arie Katz, Robert A Wesley, Mark Levine. Ann Intern Med 2004
509
22

Targeting cancer vulnerabilities with high-dose vitamin C.
Bryan Ngo, Justin M Van Riper, Lewis C Cantley, Jihye Yun. Nat Rev Cancer 2019
106
17

A family of mammalian Na+-dependent L-ascorbic acid transporters.
H Tsukaguchi, T Tokui, B Mackenzie, U V Berger, X Z Chen, Y Wang, R F Brubaker, M A Hediger. Nature 1999
637
16

Ascorbic acid: chemistry, biology and the treatment of cancer.
Juan Du, Joseph J Cullen, Garry R Buettner. Biochim Biophys Acta 2012
457
15

Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance.
M Levine, C Conry-Cantilena, Y Wang, R W Welch, P W Washko, K R Dhariwal, J B Park, A Lazarev, J F Graumlich, J King,[...]. Proc Natl Acad Sci U S A 1996
810
15

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Jihye Yun, Edouard Mullarky, Changyuan Lu, Kaitlyn N Bosch, Adam Kavalier, Keith Rivera, Jatin Roper, Iok In Christine Chio, Eugenia G Giannopoulou, Carlo Rago,[...]. Science 2015
455
15

Vitamin C. Biosynthesis, recycling and degradation in mammals.
Carole L Linster, Emile Van Schaftingen. FEBS J 2007
385
15

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice.
Qi Chen, Michael Graham Espey, Andrew Y Sun, Chaya Pooput, Kenneth L Kirk, Murali C Krishna, Deena Beneda Khosh, Jeanne Drisko, Mark Levine. Proc Natl Acad Sci U S A 2008
490
15

Regulation of the Epigenome by Vitamin C.
Juan I Young, Stephan Züchner, Gaofeng Wang. Annu Rev Nutr 2015
168
14

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.
Luisa Cimmino, Igor Dolgalev, Yubao Wang, Akihide Yoshimi, Gaëlle H Martin, Jingjing Wang, Victor Ng, Bo Xia, Matthew T Witkowski, Marisa Mitchell-Flack,[...]. Cell 2017
346
14

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues.
Qi Chen, Michael Graham Espey, Murali C Krishna, James B Mitchell, Christopher P Corpe, Garry R Buettner, Emily Shacter, Mark Levine. Proc Natl Acad Sci U S A 2005
610
13




Vitamin C in Stem Cell Reprogramming and Cancer.
Luisa Cimmino, Benjamin G Neel, Iannis Aifantis. Trends Cell Biol 2018
80
16

The Pharmacokinetics of Vitamin C.
Jens Lykkesfeldt, Pernille Tveden-Nyborg. Nutrients 2019
70
17

Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial.
Alpha A Fowler, Jonathon D Truwit, R Duncan Hite, Peter E Morris, Christine DeWilde, Anna Priday, Bernard Fisher, Leroy R Thacker, Ramesh Natarajan, Donald F Brophy,[...]. JAMA 2019
354
12

Failure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer. A controlled trial.
E T Creagan, C G Moertel, J R O'Fallon, A J Schutt, M J O'Connell, J Rubin, S Frytak. N Engl J Med 1979
365
12


Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells.
Kathryn Blaschke, Kevin T Ebata, Mohammad M Karimi, Jorge A Zepeda-Martínez, Preeti Goyal, Sahasransu Mahapatra, Angela Tam, Diana J Laird, Martin Hirst, Anjana Rao,[...]. Nature 2013
526
11

Histone demethylation by a family of JmjC domain-containing proteins.
Yu-ichi Tsukada, Jia Fang, Hediye Erdjument-Bromage, Maria E Warren, Christoph H Borchers, Paul Tempst, Yi Zhang. Nature 2006
11

Vitamin C and Immune Function.
Anitra C Carr, Silvia Maggini. Nutrients 2017
447
11

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis.
Michalis Agathocleous, Corbin E Meacham, Rebecca J Burgess, Elena Piskounova, Zhiyu Zhao, Genevieve M Crane, Brianna L Cowin, Emily Bruner, Malea M Murphy, Weina Chen,[...]. Nature 2017
245
11

The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner.
Tao Wang, Keshi Chen, Xiaoming Zeng, Jianguo Yang, Yun Wu, Xi Shi, Baoming Qin, Lingwen Zeng, Miguel Angel Esteban, Guangjin Pan,[...]. Cell Stem Cell 2011
317
10


Regulation of vitamin C homeostasis during deficiency.
Maiken Lindblad, Pernille Tveden-Nyborg, Jens Lykkesfeldt. Nutrients 2013
67
13

Vitamin C: a concentration-function approach yields pharmacology and therapeutic discoveries.
Mark Levine, Sebastian J Padayatty, Michael Graham Espey. Adv Nutr 2011
181
9

Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo.
Qi Chen, Michael Graham Espey, Andrew Y Sun, Je-Hyuk Lee, Murali C Krishna, Emily Shacter, Peter L Choyke, Chaya Pooput, Kenneth L Kirk, Garry R Buettner,[...]. Proc Natl Acad Sci U S A 2007
423
9

Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid.
S C Rumsey, O Kwon, G W Xu, C F Burant, I Simpson, M Levine. J Biol Chem 1997
343
9

Vitamin C modulates TET1 function during somatic cell reprogramming.
Jiekai Chen, Lin Guo, Lei Zhang, Haoyu Wu, Jiaqi Yang, He Liu, Xiaoshan Wang, Xiao Hu, Tianpeng Gu, Zhiwei Zhou,[...]. Nat Genet 2013
199
9

Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals.
Ruichuan Yin, Shi-Qing Mao, Bailin Zhao, Zechen Chong, Ying Yang, Chao Zhao, Dapeng Zhang, Hua Huang, Juan Gao, Zheng Li,[...]. J Am Chem Soc 2013
355
9

Criteria and recommendations for vitamin C intake.
M Levine, S C Rumsey, R Daruwala, J B Park, Y Wang. JAMA 1999
292
9

Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis.
Alpha A Fowler, Aamer A Syed, Shelley Knowlson, Robin Sculthorpe, Don Farthing, Christine DeWilde, Christine A Farthing, Terri L Larus, Erika Martin, Donald F Brophy,[...]. J Transl Med 2014
268
9

Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes.
Anitra C Carr, Patrice C Rosengrave, Simone Bayer, Steve Chambers, Jan Mehrtens, Geoff M Shaw. Crit Care 2017
163
9

Vitamin C increases viral mimicry induced by 5-aza-2'-deoxycytidine.
Minmin Liu, Hitoshi Ohtani, Wanding Zhou, Andreas Due Ørskov, Jessica Charlet, Yang W Zhang, Hui Shen, Stephen B Baylin, Gangning Liang, Kirsten Grønbæk,[...]. Proc Natl Acad Sci U S A 2016
101
9

High-dose parenteral ascorbate enhanced chemosensitivity of ovarian cancer and reduced toxicity of chemotherapy.
Yan Ma, Julia Chapman, Mark Levine, Kishore Polireddy, Jeanne Drisko, Qi Chen. Sci Transl Med 2014
234
8

Vitamin C preferentially kills cancer stem cells in hepatocellular carcinoma via SVCT-2.
Hongwei Lv, Changzheng Wang, Tian Fang, Ting Li, Guishuai Lv, Qin Han, Wen Yang, Hongyang Wang. NPJ Precis Oncol 2018
67
11

Dietary Vitamin C in Human Health.
Matthew Granger, Peter Eck. Adv Food Nutr Res 2018
51
15

Regulation of vitamin C transport.
John X Wilson. Annu Rev Nutr 2005
212
8

Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8.
Christopher P Corpe, Peter Eck, Jin Wang, Hadi Al-Hasani, Mark Levine. J Biol Chem 2013
75
10

Vitamin C as an antioxidant: evaluation of its role in disease prevention.
Sebastian J Padayatty, Arie Katz, Yaohui Wang, Peter Eck, Oran Kwon, Je-Hyuk Lee, Shenglin Chen, Christopher Corpe, Anand Dutta, Sudhir K Dutta,[...]. J Am Coll Nutr 2003
723
8

Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival.
Sotiria Sotiriou, Suzana Gispert, Jun Cheng, Yaohui Wang, Amy Chen, Shelley Hoogstraten-Miller, Georgina F Miller, Oran Kwon, Mark Levine, Susan H Guttentag,[...]. Nat Med 2002
259
8

Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice.
Christopher P Corpe, Hongbin Tu, Peter Eck, Jin Wang, Robert Faulhaber-Walter, Jurgen Schnermann, Sam Margolis, Sebastian Padayatty, He Sun, Yaohui Wang,[...]. J Clin Invest 2010
97
8

SVCT1 and SVCT2: key proteins for vitamin C uptake.
I Savini, A Rossi, C Pierro, L Avigliano, M V Catani. Amino Acids 2008
229
8

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial.
Tomoko Fujii, Nora Luethi, Paul J Young, Daniel R Frei, Glenn M Eastwood, Craig J French, Adam M Deane, Yahya Shehabi, Ludhmila A Hajjar, Gisele Oliveira,[...]. JAMA 2020
190
8

Systematic Review of Intravenous Ascorbate in Cancer Clinical Trials.
Gina Nauman, Javaughn Corey Gray, Rose Parkinson, Mark Levine, Channing J Paller. Antioxidants (Basel) 2018
45
17

Vitamin C deficiency in cancer patients.
Catriona R Mayland, Michael I Bennett, Keith Allan. Palliat Med 2005
102
8

Ascorbic acid serum levels are reduced in patients with hematological malignancies.
Mirelle J A J Huijskens, Will K W H Wodzig, Mateusz Walczak, Wilfred T V Germeraad, Gerard M J Bos. Results Immunol 2016
48
16

Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer.
Christopher M Stephenson, Robert D Levin, Thomas Spector, Christopher G Lis. Cancer Chemother Pharmacol 2013
130
8



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.