Erin Quan Toyama, Sébastien Herzig, Julien Courchet, Tommy L Lewis, Oliver C Losón, Kristina Hellberg, Nathan P Young, Hsiuchen Chen, Franck Polleux, David C Chan, Reuben J Shaw. Science 2016
Times Cited: 555
Times Cited: 555
Times Cited
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Similarity
AMPK: guardian of metabolism and mitochondrial homeostasis.
Sébastien Herzig, Reuben J Shaw. Nat Rev Mol Cell Biol 2018
Sébastien Herzig, Reuben J Shaw. Nat Rev Mol Cell Biol 2018
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Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.
Daniel F Egan, David B Shackelford, Maria M Mihaylova, Sara Gelino, Rebecca A Kohnz, William Mair, Debbie S Vasquez, Aashish Joshi, Dana M Gwinn, Rebecca Taylor,[...]. Science 2011
Daniel F Egan, David B Shackelford, Maria M Mihaylova, Sara Gelino, Rebecca A Kohnz, William Mair, Debbie S Vasquez, Aashish Joshi, Dana M Gwinn, Rebecca Taylor,[...]. Science 2011
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Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.
Lei Liu, Du Feng, Guo Chen, Ming Chen, Qiaoxia Zheng, Pingping Song, Qi Ma, Chongzhuo Zhu, Rui Wang, Wanjun Qi,[...]. Nat Cell Biol 2012
Lei Liu, Du Feng, Guo Chen, Ming Chen, Qiaoxia Zheng, Pingping Song, Qi Ma, Chongzhuo Zhu, Rui Wang, Wanjun Qi,[...]. Nat Cell Biol 2012
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Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission.
Oliver C Losón, Zhiyin Song, Hsiuchen Chen, David C Chan. Mol Biol Cell 2013
Oliver C Losón, Zhiyin Song, Hsiuchen Chen, David C Chan. Mol Biol Cell 2013
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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
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Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death.
J Thomas Cribbs, Stefan Strack. EMBO Rep 2007
J Thomas Cribbs, Stefan Strack. EMBO Rep 2007
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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
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Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.
Hsiuchen Chen, Scott A Detmer, Andrew J Ewald, Erik E Griffin, Scott E Fraser, David C Chan. J Cell Biol 2003
Hsiuchen Chen, Scott A Detmer, Andrew J Ewald, Erik E Griffin, Scott E Fraser, David C Chan. J Cell Biol 2003
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Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.
Naoko Taguchi, Naotada Ishihara, Akihiro Jofuku, Toshihiko Oka, Katsuyoshi Mihara. J Biol Chem 2007
Naoko Taguchi, Naotada Ishihara, Akihiro Jofuku, Toshihiko Oka, Katsuyoshi Mihara. J Biol Chem 2007
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Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth.
Jennifer A Kashatus, Aldo Nascimento, Lindsey J Myers, Annie Sher, Frances L Byrne, Kyle L Hoehn, Christopher M Counter, David F Kashatus. Mol Cell 2015
Jennifer A Kashatus, Aldo Nascimento, Lindsey J Myers, Annie Sher, Frances L Byrne, Kyle L Hoehn, Christopher M Counter, David F Kashatus. Mol Cell 2015
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Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor.
Yongjie Wei, Wei-Chung Chiang, Rhea Sumpter, Prashant Mishra, Beth Levine. Cell 2017
Yongjie Wei, Wei-Chung Chiang, Rhea Sumpter, Prashant Mishra, Beth Levine. Cell 2017
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Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells.
Hidenori Otera, Chunxin Wang, Megan M Cleland, Kiyoko Setoguchi, Sadaki Yokota, Richard J Youle, Katsuyoshi Mihara. J Cell Biol 2010
Hidenori Otera, Chunxin Wang, Megan M Cleland, Kiyoko Setoguchi, Sadaki Yokota, Richard J Youle, Katsuyoshi Mihara. J Cell Biol 2010
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ER tubules mark sites of mitochondrial division.
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
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Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria.
G M Cereghetti, A Stangherlin, O Martins de Brito, C R Chang, C Blackstone, P Bernardi, L Scorrano. Proc Natl Acad Sci U S A 2008
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During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.
Ligia C Gomes, Giulietta Di Benedetto, Luca Scorrano. Nat Cell Biol 2011
Ligia C Gomes, Giulietta Di Benedetto, Luca Scorrano. Nat Cell Biol 2011
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Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology.
Chuang-Rung Chang, Craig Blackstone. J Biol Chem 2007
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Mitochondrial fission facilitates the selective mitophagy of protein aggregates.
Jonathon L Burman, Sarah Pickles, Chunxin Wang, Shiori Sekine, Jose Norberto S Vargas, Zhe Zhang, Alice M Youle, Catherine L Nezich, Xufeng Wu, John A Hammer,[...]. J Cell Biol 2017
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Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation.
Angelika S Rambold, Brenda Kostelecky, Natalie Elia, Jennifer Lippincott-Schwartz. Proc Natl Acad Sci U S A 2011
Angelika S Rambold, Brenda Kostelecky, Natalie Elia, Jennifer Lippincott-Schwartz. Proc Natl Acad Sci U S A 2011
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Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice.
Naotada Ishihara, Masatoshi Nomura, Akihiro Jofuku, Hiroki Kato, Satoshi O Suzuki, Keiji Masuda, Hidenori Otera, Yae Nakanishi, Ikuya Nonaka, Yu-Ichi Goto,[...]. Nat Cell Biol 2009
Naotada Ishihara, Masatoshi Nomura, Akihiro Jofuku, Hiroki Kato, Satoshi O Suzuki, Keiji Masuda, Hidenori Otera, Yae Nakanishi, Ikuya Nonaka, Yu-Ichi Goto,[...]. Nat Cell Biol 2009
10
Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells.
Charleen T Chu, Jing Ji, Ruben K Dagda, Jian Fei Jiang, Yulia Y Tyurina, Alexandr A Kapralov, Vladimir A Tyurin, Naveena Yanamala, Indira H Shrivastava, Dariush Mohammadyani,[...]. Nat Cell Biol 2013
Charleen T Chu, Jing Ji, Ruben K Dagda, Jian Fei Jiang, Yulia Y Tyurina, Alexandr A Kapralov, Vladimir A Tyurin, Naveena Yanamala, Indira H Shrivastava, Dariush Mohammadyani,[...]. Nat Cell Biol 2013
9
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity.
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
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PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria.
Yun Chen, Gerald W Dorn. Science 2013
Yun Chen, Gerald W Dorn. Science 2013
9
ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy.
Wenxian Wu, Weili Tian, Zhe Hu, Guo Chen, Lei Huang, Wen Li, Xingli Zhang, Peng Xue, Changqian Zhou, Lei Liu,[...]. EMBO Rep 2014
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AMPK: a nutrient and energy sensor that maintains energy homeostasis.
D Grahame Hardie, Fiona A Ross, Simon A Hawley. Nat Rev Mol Cell Biol 2012
D Grahame Hardie, Fiona A Ross, Simon A Hawley. Nat Rev Mol Cell Biol 2012
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Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells.
E Smirnova, L Griparic, D L Shurland, A M van der Bliek. Mol Biol Cell 2001
E Smirnova, L Griparic, D L Shurland, A M van der Bliek. Mol Biol Cell 2001
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AMPK phosphorylation of raptor mediates a metabolic checkpoint.
Dana M Gwinn, David B Shackelford, Daniel F Egan, Maria M Mihaylova, Annabelle Mery, Debbie S Vasquez, Benjamin E Turk, Reuben J Shaw. Mol Cell 2008
Dana M Gwinn, David B Shackelford, Daniel F Egan, Maria M Mihaylova, Annabelle Mery, Debbie S Vasquez, Benjamin E Turk, Reuben J Shaw. Mol Cell 2008
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The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission.
Ruchika Anand, Timothy Wai, Michael J Baker, Nikolay Kladt, Astrid C Schauss, Elena Rugarli, Thomas Langer. J Cell Biol 2014
Ruchika Anand, Timothy Wai, Michael J Baker, Nikolay Kladt, Astrid C Schauss, Elena Rugarli, Thomas Langer. J Cell Biol 2014
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An actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2.
Farida Korobova, Vinay Ramabhadran, Henry N Higgs. Science 2013
Farida Korobova, Vinay Ramabhadran, Henry N Higgs. Science 2013
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Regulation of mitochondrial morphology through proteolytic cleavage of OPA1.
Naotada Ishihara, Yuu Fujita, Toshihiko Oka, Katsuyoshi Mihara. EMBO J 2006
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Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance.
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
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Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy.
Rhianna C Laker, Joshua C Drake, Rebecca J Wilson, Vitor A Lira, Bevan M Lewellen, Karen A Ryall, Carleigh C Fisher, Mei Zhang, Jeffrey J Saucerman, Laurie J Goodyear,[...]. Nat Commun 2017
Rhianna C Laker, Joshua C Drake, Rebecca J Wilson, Vitor A Lira, Bevan M Lewellen, Karen A Ryall, Carleigh C Fisher, Mei Zhang, Jeffrey J Saucerman, Laurie J Goodyear,[...]. Nat Commun 2017
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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.
Sven Geisler, Kira M Holmström, Diana Skujat, Fabienne C Fiesel, Oliver C Rothfuss, Philipp J Kahle, Wolfdieter Springer. Nat Cell Biol 2010
Sven Geisler, Kira M Holmström, Diana Skujat, Fabienne C Fiesel, Oliver C Rothfuss, Philipp J Kahle, Wolfdieter Springer. Nat Cell Biol 2010
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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.
Chandana Kondapalli, Agne Kazlauskaite, Ning Zhang, Helen I Woodroof, David G Campbell, Robert Gourlay, Lynn Burchell, Helen Walden, Thomas J Macartney, Maria Deak,[...]. Open Biol 2012
Chandana Kondapalli, Agne Kazlauskaite, Ning Zhang, Helen I Woodroof, David G Campbell, Robert Gourlay, Lynn Burchell, Helen Walden, Thomas J Macartney, Maria Deak,[...]. Open Biol 2012
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Mitofusin 2 tethers endoplasmic reticulum to mitochondria.
Olga Martins de Brito, Luca Scorrano. Nature 2008
Olga Martins de Brito, Luca Scorrano. Nature 2008
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Ubiquitin is phosphorylated by PINK1 to activate parkin.
Fumika Koyano, Kei Okatsu, Hidetaka Kosako, Yasushi Tamura, Etsu Go, Mayumi Kimura, Yoko Kimura, Hikaru Tsuchiya, Hidehito Yoshihara, Takatsugu Hirokawa,[...]. Nature 2014
Fumika Koyano, Kei Okatsu, Hidetaka Kosako, Yasushi Tamura, Etsu Go, Mayumi Kimura, Yoko Kimura, Hikaru Tsuchiya, Hidehito Yoshihara, Takatsugu Hirokawa,[...]. Nature 2014
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FKBP8 recruits LC3A to mediate Parkin-independent mitophagy.
Zambarlal Bhujabal, Åsa B Birgisdottir, Eva Sjøttem, Hanne B Brenne, Aud Øvervatn, Sabrina Habisov, Vladimir Kirkin, Trond Lamark, Terje Johansen. EMBO Rep 2017
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The constriction and scission machineries involved in mitochondrial fission.
Felix Kraus, Michael T Ryan. J Cell Sci 2017
Felix Kraus, Michael T Ryan. J Cell Sci 2017
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Essential role for Nix in autophagic maturation of erythroid cells.
Hector Sandoval, Perumal Thiagarajan, Swapan K Dasgupta, Armin Schumacher, Josef T Prchal, Min Chen, Jin Wang. Nature 2008
Hector Sandoval, Perumal Thiagarajan, Swapan K Dasgupta, Armin Schumacher, Josef T Prchal, Min Chen, Jin Wang. Nature 2008
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Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity.
Naotada Ishihara, Yuka Eura, Katsuyoshi Mihara. J Cell Sci 2004
Naotada Ishihara, Yuka Eura, Katsuyoshi Mihara. J Cell Sci 2004
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Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.
Guillaume P Leboucher, Yien Che Tsai, Mei Yang, Kristin C Shaw, Ming Zhou, Timothy D Veenstra, Michael H Glickman, Allan M Weissman. Mol Cell 2012
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AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha.
Sibylle Jäger, Christoph Handschin, Julie St-Pierre, Bruce M Spiegelman. Proc Natl Acad Sci U S A 2007
Sibylle Jäger, Christoph Handschin, Julie St-Pierre, Bruce M Spiegelman. Proc Natl Acad Sci U S A 2007
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Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors.
Madhavika N Serasinghe, Shira Y Wieder, Thibaud T Renault, Rana Elkholi, James J Asciolla, Jonathon L Yao, Omar Jabado, Kyle Hoehn, Yusuke Kageyama, Hiromi Sesaki,[...]. Mol Cell 2015
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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
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Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation.
Tomokazu Murakawa, Osamu Yamaguchi, Ayako Hashimoto, Shungo Hikoso, Toshihiro Takeda, Takafumi Oka, Hiroki Yasui, Hiromichi Ueda, Yasuhiro Akazawa, Hiroyuki Nakayama,[...]. Nat Commun 2015
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A regulatory signaling loop comprising the PGAM5 phosphatase and CK2 controls receptor-mediated mitophagy.
Guo Chen, Zhe Han, Du Feng, Yanfang Chen, Linbo Chen, Hao Wu, Li Huang, Changqian Zhou, Xiangyu Cai, Changying Fu,[...]. Mol Cell 2014
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FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.
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Autophagosomes form at ER-mitochondria contact sites.
Maho Hamasaki, Nobumichi Furuta, Atsushi Matsuda, Akiko Nezu, Akitsugu Yamamoto, Naonobu Fujita, Hiroko Oomori, Takeshi Noda, Tokuko Haraguchi, Yasushi Hiraoka,[...]. Nature 2013
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7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.