Hao Yin, Chun-Qing Song, Joseph R Dorkin, Lihua J Zhu, Yingxiang Li, Qiongqiong Wu, Angela Park, Junghoon Yang, Sneha Suresh, Aizhan Bizhanova, Ankit Gupta, Mehmet F Bolukbasi, Stephen Walsh, Roman L Bogorad, Guangping Gao, Zhiping Weng, Yizhou Dong, Victor Koteliansky, Scot A Wolfe, Robert Langer, Wen Xue, Daniel G Anderson. Nat Biotechnol 2016
Times Cited: 533
Times Cited: 533
Times Cited
Times Co-cited
Similarity
Multiplex genome engineering using CRISPR/Cas systems.
Le Cong, F Ann Ran, David Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, Patrick D Hsu, Xuebing Wu, Wenyan Jiang, Luciano A Marraffini,[...]. Science 2013
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A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
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RNA-guided human genome engineering via Cas9.
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
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Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair.
Kunwoo Lee, Michael Conboy, Hyo Min Park, Fuguo Jiang, Hyun Jin Kim, Mark A Dewitt, Vanessa A Mackley, Kevin Chang, Anirudh Rao, Colin Skinner,[...]. Nat Biomed Eng 2017
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A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing.
Jonathan D Finn, Amy Rhoden Smith, Mihir C Patel, Lucinda Shaw, Madeleine R Youniss, Jane van Heteren, Tanner Dirstine, Corey Ciullo, Reynald Lescarbeau, Jessica Seitzer,[...]. Cell Rep 2018
Jonathan D Finn, Amy Rhoden Smith, Mihir C Patel, Lucinda Shaw, Madeleine R Youniss, Jane van Heteren, Tanner Dirstine, Corey Ciullo, Reynald Lescarbeau, Jessica Seitzer,[...]. Cell Rep 2018
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In vivo genome editing using Staphylococcus aureus Cas9.
F Ann Ran, Le Cong, Winston X Yan, David A Scott, Jonathan S Gootenberg, Andrea J Kriz, Bernd Zetsche, Ophir Shalem, Xuebing Wu, Kira S Makarova,[...]. Nature 2015
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Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo.
John A Zuris, David B Thompson, Yilai Shu, John P Guilinger, Jeffrey L Bessen, Johnny H Hu, Morgan L Maeder, J Keith Joung, Zheng-Yi Chen, David R Liu. Nat Biotechnol 2015
John A Zuris, David B Thompson, Yilai Shu, John P Guilinger, Jeffrey L Bessen, Johnny H Hu, Morgan L Maeder, J Keith Joung, Zheng-Yi Chen, David R Liu. Nat Biotechnol 2015
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Identification of preexisting adaptive immunity to Cas9 proteins in humans.
Carsten T Charlesworth, Priyanka S Deshpande, Daniel P Dever, Joab Camarena, Viktor T Lemgart, M Kyle Cromer, Christopher A Vakulskas, Michael A Collingwood, Liyang Zhang, Nicole M Bode,[...]. Nat Med 2019
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Genome editing. The new frontier of genome engineering with CRISPR-Cas9.
Jennifer A Doudna, Emmanuelle Charpentier. Science 2014
Jennifer A Doudna, Emmanuelle Charpentier. Science 2014
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Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA.
Jason B Miller, Shuyuan Zhang, Petra Kos, Hu Xiong, Kejin Zhou, Sofya S Perelman, Hao Zhu, Daniel J Siegwart. Angew Chem Int Ed Engl 2017
Jason B Miller, Shuyuan Zhang, Petra Kos, Hu Xiong, Kejin Zhou, Sofya S Perelman, Hao Zhu, Daniel J Siegwart. Angew Chem Int Ed Engl 2017
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Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.
Hao Yin, Wen Xue, Sidi Chen, Roman L Bogorad, Eric Benedetti, Markus Grompe, Victor Koteliansky, Phillip A Sharp, Tyler Jacks, Daniel G Anderson. Nat Biotechnol 2014
Hao Yin, Wen Xue, Sidi Chen, Roman L Bogorad, Eric Benedetti, Markus Grompe, Victor Koteliansky, Phillip A Sharp, Tyler Jacks, Daniel G Anderson. Nat Biotechnol 2014
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Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
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Search-and-replace genome editing without double-strand breaks or donor DNA.
Andrew V Anzalone, Peyton B Randolph, Jessie R Davis, Alexander A Sousa, Luke W Koblan, Jonathan M Levy, Peter J Chen, Christopher Wilson, Gregory A Newby, Aditya Raguram,[...]. Nature 2019
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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
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Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.
Hao Yin, Chun-Qing Song, Sneha Suresh, Qiongqiong Wu, Stephen Walsh, Luke Hyunsik Rhym, Esther Mintzer, Mehmet Fatih Bolukbasi, Lihua Julie Zhu, Kevin Kauffman,[...]. Nat Biotechnol 2017
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Genome engineering using the CRISPR-Cas9 system.
F Ann Ran, Patrick D Hsu, Jason Wright, Vineeta Agarwala, David A Scott, Feng Zhang. Nat Protoc 2013
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Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins.
Sojung Kim, Daesik Kim, Seung Woo Cho, Jungeun Kim, Jin-Soo Kim. Genome Res 2014
Sojung Kim, Daesik Kim, Seung Woo Cho, Jungeun Kim, Jin-Soo Kim. Genome Res 2014
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Therapeutic genome editing: prospects and challenges.
David Benjamin Turitz Cox, Randall Jeffrey Platt, Feng Zhang. Nat Med 2015
David Benjamin Turitz Cox, Randall Jeffrey Platt, Feng Zhang. Nat Med 2015
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Self-assembled DNA nanoclews for the efficient delivery of CRISPR-Cas9 for genome editing.
Wujin Sun, Wenyan Ji, Jordan M Hall, Quanyin Hu, Chao Wang, Chase L Beisel, Zhen Gu. Angew Chem Int Ed Engl 2015
Wujin Sun, Wenyan Ji, Jordan M Hall, Quanyin Hu, Chao Wang, Chase L Beisel, Zhen Gu. Angew Chem Int Ed Engl 2015
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A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice.
Yang Yang, Lili Wang, Peter Bell, Deirdre McMenamin, Zhenning He, John White, Hongwei Yu, Chenyu Xu, Hiroki Morizono, Kiran Musunuru,[...]. Nat Biotechnol 2016
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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
Bernd Zetsche, Jonathan S Gootenberg, Omar O Abudayyeh, Ian M Slaymaker, Kira S Makarova, Patrick Essletzbichler, Sara E Volz, Julia Joung, John van der Oost, Aviv Regev,[...]. Cell 2015
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CRISPR-Cas9 knockin mice for genome editing and cancer modeling.
Randall J Platt, Sidi Chen, Yang Zhou, Michael J Yim, Lukasz Swiech, Hannah R Kempton, James E Dahlman, Oren Parnas, Thomas M Eisenhaure, Marko Jovanovic,[...]. Cell 2014
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Development and applications of CRISPR-Cas9 for genome engineering.
Patrick D Hsu, Eric S Lander, Feng Zhang. Cell 2014
Patrick D Hsu, Eric S Lander, Feng Zhang. Cell 2014
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Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.
Giedrius Gasiunas, Rodolphe Barrangou, Philippe Horvath, Virginijus Siksnys. Proc Natl Acad Sci U S A 2012
Giedrius Gasiunas, Rodolphe Barrangou, Philippe Horvath, Virginijus Siksnys. Proc Natl Acad Sci U S A 2012
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High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.
Benjamin P Kleinstiver, Vikram Pattanayak, Michelle S Prew, Shengdar Q Tsai, Nhu T Nguyen, Zongli Zheng, J Keith Joung. Nature 2016
Benjamin P Kleinstiver, Vikram Pattanayak, Michelle S Prew, Shengdar Q Tsai, Nhu T Nguyen, Zongli Zheng, J Keith Joung. Nature 2016
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Direct Cytosolic Delivery of CRISPR/Cas9-Ribonucleoprotein for Efficient Gene Editing.
Rubul Mout, Moumita Ray, Gulen Yesilbag Tonga, Yi-Wei Lee, Tristan Tay, Kanae Sasaki, Vincent M Rotello. ACS Nano 2017
Rubul Mout, Moumita Ray, Gulen Yesilbag Tonga, Yi-Wei Lee, Tristan Tay, Kanae Sasaki, Vincent M Rotello. ACS Nano 2017
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Delivering CRISPR: a review of the challenges and approaches.
Christopher A Lino, Jason C Harper, James P Carney, Jerilyn A Timlin. Drug Deliv 2018
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Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours.
Bumwhee Lee, Kunwoo Lee, Shree Panda, Rodrigo Gonzales-Rojas, Anthony Chong, Vladislav Bugay, Hyo Min Park, Robert Brenner, Niren Murthy, Hye Young Lee. Nat Biomed Eng 2018
Bumwhee Lee, Kunwoo Lee, Shree Panda, Rodrigo Gonzales-Rojas, Anthony Chong, Vladislav Bugay, Hyo Min Park, Robert Brenner, Niren Murthy, Hye Young Lee. Nat Biomed Eng 2018
14
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.
Ming Wang, John A Zuris, Fantao Meng, Holly Rees, Shuo Sun, Pu Deng, Yong Han, Xue Gao, Dimitra Pouli, Qi Wu,[...]. Proc Natl Acad Sci U S A 2016
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14
A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing.
Guojun Chen, Amr A Abdeen, Yuyuan Wang, Pawan K Shahi, Samantha Robertson, Ruosen Xie, Masatoshi Suzuki, Bikash R Pattnaik, Krishanu Saha, Shaoqin Gong. Nat Nanotechnol 2019
Guojun Chen, Amr A Abdeen, Yuyuan Wang, Pawan K Shahi, Samantha Robertson, Ruosen Xie, Masatoshi Suzuki, Bikash R Pattnaik, Krishanu Saha, Shaoqin Gong. Nat Nanotechnol 2019
14
Treatment of a metabolic liver disease by in vivo genome base editing in adult mice.
Lukas Villiger, Hiu Man Grisch-Chan, Helen Lindsay, Femke Ringnalda, Chiara B Pogliano, Gabriella Allegri, Ralph Fingerhut, Johannes Häberle, Joao Matos, Mark D Robinson,[...]. Nat Med 2018
Lukas Villiger, Hiu Man Grisch-Chan, Helen Lindsay, Femke Ringnalda, Chiara B Pogliano, Gabriella Allegri, Ralph Fingerhut, Johannes Häberle, Joao Matos, Mark D Robinson,[...]. Nat Med 2018
14
CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia.
Haydar Frangoul, David Altshuler, M Domenica Cappellini, Yi-Shan Chen, Jennifer Domm, Brenda K Eustace, Juergen Foell, Josu de la Fuente, Stephan Grupp, Rupert Handgretinger,[...]. N Engl J Med 2021
Haydar Frangoul, David Altshuler, M Domenica Cappellini, Yi-Shan Chen, Jennifer Domm, Brenda K Eustace, Juergen Foell, Josu de la Fuente, Stephan Grupp, Rupert Handgretinger,[...]. N Engl J Med 2021
14
CRISPR provides acquired resistance against viruses in prokaryotes.
Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau, Melissa Richards, Patrick Boyaval, Sylvain Moineau, Dennis A Romero, Philippe Horvath. Science 2007
Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau, Melissa Richards, Patrick Boyaval, Sylvain Moineau, Dennis A Romero, Philippe Horvath. Science 2007
13
Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles.
Ji Liu, Jin Chang, Ying Jiang, Xiandi Meng, Tianmeng Sun, Lanqun Mao, Qiaobing Xu, Ming Wang. Adv Mater 2019
Ji Liu, Jin Chang, Ying Jiang, Xiandi Meng, Tianmeng Sun, Lanqun Mao, Qiaobing Xu, Ming Wang. Adv Mater 2019
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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.
Yanfang Fu, Jennifer A Foden, Cyd Khayter, Morgan L Maeder, Deepak Reyon, J Keith Joung, Jeffry D Sander. Nat Biotechnol 2013
Yanfang Fu, Jennifer A Foden, Cyd Khayter, Morgan L Maeder, Deepak Reyon, J Keith Joung, Jeffry D Sander. Nat Biotechnol 2013
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A multifunctional AAV-CRISPR-Cas9 and its host response.
Wei Leong Chew, Mohammadsharif Tabebordbar, Jason K W Cheng, Prashant Mali, Elizabeth Y Wu, Alex H M Ng, Kexian Zhu, Amy J Wagers, George M Church. Nat Methods 2016
Wei Leong Chew, Mohammadsharif Tabebordbar, Jason K W Cheng, Prashant Mali, Elizabeth Y Wu, Alex H M Ng, Kexian Zhu, Amy J Wagers, George M Church. Nat Methods 2016
13
In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.
Christopher E Nelson, Chady H Hakim, David G Ousterout, Pratiksha I Thakore, Eirik A Moreb, Ruth M Castellanos Rivera, Sarina Madhavan, Xiufang Pan, F Ann Ran, Winston X Yan,[...]. Science 2016
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13
Rationally engineered Cas9 nucleases with improved specificity.
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
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A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo.
Chao Jiang, Miao Mei, Bin Li, Xiurui Zhu, Wenhong Zu, Yujie Tian, Qiannan Wang, Yong Guo, Yizhou Dong, Xu Tan. Cell Res 2017
Chao Jiang, Miao Mei, Bin Li, Xiurui Zhu, Wenhong Zu, Yujie Tian, Qiannan Wang, Yong Guo, Yizhou Dong, Xu Tan. Cell Res 2017
12
Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA.
Suresh Ramakrishna, Abu-Bonsrah Kwaku Dad, Jagadish Beloor, Ramu Gopalappa, Sang-Kyung Lee, Hyongbum Kim. Genome Res 2014
Suresh Ramakrishna, Abu-Bonsrah Kwaku Dad, Jagadish Beloor, Ramu Gopalappa, Sang-Kyung Lee, Hyongbum Kim. Genome Res 2014
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CRISPR/Cas9-Based Genome Editing for Disease Modeling and Therapy: Challenges and Opportunities for Nonviral Delivery.
Hong-Xia Wang, Mingqiang Li, Ciaran M Lee, Syandan Chakraborty, Hae-Won Kim, Gang Bao, Kam W Leong. Chem Rev 2017
Hong-Xia Wang, Mingqiang Li, Ciaran M Lee, Syandan Chakraborty, Hae-Won Kim, Gang Bao, Kam W Leong. Chem Rev 2017
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Repair of double-strand breaks induced by CRISPR-Cas9 leads to large deletions and complex rearrangements.
Michael Kosicki, Kärt Tomberg, Allan Bradley. Nat Biotechnol 2018
Michael Kosicki, Kärt Tomberg, Allan Bradley. Nat Biotechnol 2018
12
Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes.
Brett T Staahl, Madhurima Benekareddy, Claire Coulon-Bainier, Ashwin A Banfal, Stephen N Floor, Jennifer K Sabo, Cole Urnes, Gabriela Acevedo Munares, Anirvan Ghosh, Jennifer A Doudna. Nat Biotechnol 2017
Brett T Staahl, Madhurima Benekareddy, Claire Coulon-Bainier, Ashwin A Banfal, Stephen N Floor, Jennifer K Sabo, Cole Urnes, Gabriela Acevedo Munares, Anirvan Ghosh, Jennifer A Doudna. Nat Biotechnol 2017
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Non-viral vectors for gene-based therapy.
Hao Yin, Rosemary L Kanasty, Ahmed A Eltoukhy, Arturo J Vegas, J Robert Dorkin, Daniel G Anderson. Nat Rev Genet 2014
Hao Yin, Rosemary L Kanasty, Ahmed A Eltoukhy, Arturo J Vegas, J Robert Dorkin, Daniel G Anderson. Nat Rev Genet 2014
12
In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.
Keiichiro Suzuki, Yuji Tsunekawa, Reyna Hernandez-Benitez, Jun Wu, Jie Zhu, Euiseok J Kim, Fumiyuki Hatanaka, Mako Yamamoto, Toshikazu Araoka, Zhe Li,[...]. Nature 2016
Keiichiro Suzuki, Yuji Tsunekawa, Reyna Hernandez-Benitez, Jun Wu, Jie Zhu, Euiseok J Kim, Fumiyuki Hatanaka, Mako Yamamoto, Toshikazu Araoka, Zhe Li,[...]. Nature 2016
12
CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy.
Daniel Rosenblum, Anna Gutkin, Ranit Kedmi, Srinivas Ramishetti, Nuphar Veiga, Ashley M Jacobi, Mollie S Schubert, Dinorah Friedmann-Morvinski, Zvi R Cohen, Mark A Behlke,[...]. Sci Adv 2020
Daniel Rosenblum, Anna Gutkin, Ranit Kedmi, Srinivas Ramishetti, Nuphar Veiga, Ashley M Jacobi, Mollie S Schubert, Dinorah Friedmann-Morvinski, Zvi R Cohen, Mark A Behlke,[...]. Sci Adv 2020
16
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis.
Julian D Gillmore, Ed Gane, Jorg Taubel, Justin Kao, Marianna Fontana, Michael L Maitland, Jessica Seitzer, Daniel O'Connell, Kathryn R Walsh, Kristy Wood,[...]. N Engl J Med 2021
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12
Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy.
Christopher E Nelson, Yaoying Wu, Matthew P Gemberling, Matthew L Oliver, Matthew A Waller, Joel D Bohning, Jacqueline N Robinson-Hamm, Karen Bulaklak, Ruth M Castellanos Rivera, Joel H Collier,[...]. Nat Med 2019
Christopher E Nelson, Yaoying Wu, Matthew P Gemberling, Matthew L Oliver, Matthew A Waller, Joel D Bohning, Jacqueline N Robinson-Hamm, Karen Bulaklak, Ruth M Castellanos Rivera, Joel H Collier,[...]. Nat Med 2019
11
Targeted homology-directed repair in blood stem and progenitor cells with CRISPR nanoformulations.
Reza Shahbazi, Gabriella Sghia-Hughes, Jack L Reid, Sara Kubek, Kevin G Haworth, Olivier Humbert, Hans-Peter Kiem, Jennifer E Adair. Nat Mater 2019
Reza Shahbazi, Gabriella Sghia-Hughes, Jack L Reid, Sara Kubek, Kevin G Haworth, Olivier Humbert, Hans-Peter Kiem, Jennifer E Adair. Nat Mater 2019
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Endosomal Escape and Delivery of CRISPR/Cas9 Genome Editing Machinery Enabled by Nanoscale Zeolitic Imidazolate Framework.
Shahad K Alsaiari, Sachin Patil, Mram Alyami, Kholod O Alamoudi, Fajr A Aleisa, Jasmeen S Merzaban, Mo Li, Niveen M Khashab. J Am Chem Soc 2018
Shahad K Alsaiari, Sachin Patil, Mram Alyami, Kholod O Alamoudi, Fajr A Aleisa, Jasmeen S Merzaban, Mo Li, Niveen M Khashab. J Am Chem Soc 2018
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.