Stephen Neidle. J Med Chem 2016
Times Cited: 300
Times Cited: 300
Times Cited
Times Co-cited
Similarity
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription.
Adam Siddiqui-Jain, Cory L Grand, David J Bearss, Laurence H Hurley. Proc Natl Acad Sci U S A 2002
Adam Siddiqui-Jain, Cory L Grand, David J Bearss, Laurence H Hurley. Proc Natl Acad Sci U S A 2002
36
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
Shankar Balasubramanian, Laurence H Hurley, Stephen Neidle. Nat Rev Drug Discov 2011
Shankar Balasubramanian, Laurence H Hurley, Stephen Neidle. Nat Rev Drug Discov 2011
35
High-throughput sequencing of DNA G-quadruplex structures in the human genome.
Vicki S Chambers, Giovanni Marsico, Jonathan M Boutell, Marco Di Antonio, Geoffrey P Smith, Shankar Balasubramanian. Nat Biotechnol 2015
Vicki S Chambers, Giovanni Marsico, Jonathan M Boutell, Marco Di Antonio, Geoffrey P Smith, Shankar Balasubramanian. Nat Biotechnol 2015
32
G-quadruplexes and their regulatory roles in biology.
Daniela Rhodes, Hans J Lipps. Nucleic Acids Res 2015
Daniela Rhodes, Hans J Lipps. Nucleic Acids Res 2015
32
The regulation and functions of DNA and RNA G-quadruplexes.
Dhaval Varshney, Jochen Spiegel, Katherine Zyner, David Tannahill, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2020
Dhaval Varshney, Jochen Spiegel, Katherine Zyner, David Tannahill, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2020
31
Quantitative visualization of DNA G-quadruplex structures in human cells.
Giulia Biffi, David Tannahill, John McCafferty, Shankar Balasubramanian. Nat Chem 2013
Giulia Biffi, David Tannahill, John McCafferty, Shankar Balasubramanian. Nat Chem 2013
30
Quadruplex DNA: sequence, topology and structure.
Sarah Burge, Gary N Parkinson, Pascale Hazel, Alan K Todd, Stephen Neidle. Nucleic Acids Res 2006
Sarah Burge, Gary N Parkinson, Pascale Hazel, Alan K Todd, Stephen Neidle. Nucleic Acids Res 2006
28
G-quadruplex structures mark human regulatory chromatin.
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
27
The Structure and Function of DNA G-Quadruplexes.
Jochen Spiegel, Santosh Adhikari, Shankar Balasubramanian. Trends Chem 2020
Jochen Spiegel, Santosh Adhikari, Shankar Balasubramanian. Trends Chem 2020
23
Prevalence of quadruplexes in the human genome.
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2005
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2005
22
DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential.
Robert Hänsel-Hertsch, Marco Di Antonio, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2017
Robert Hänsel-Hertsch, Marco Di Antonio, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2017
20
19
G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy.
Emanuela Ruggiero, Sara N Richter. Nucleic Acids Res 2018
Emanuela Ruggiero, Sara N Richter. Nucleic Acids Res 2018
19
DNA secondary structures: stability and function of G-quadruplex structures.
Matthew L Bochman, Katrin Paeschke, Virginia A Zakian. Nat Rev Genet 2012
Matthew L Bochman, Katrin Paeschke, Virginia A Zakian. Nat Rev Genet 2012
19
A hitchhiker's guide to G-quadruplex ligands.
David Monchaud, Marie-Paule Teulade-Fichou. Org Biomol Chem 2008
David Monchaud, Marie-Paule Teulade-Fichou. Org Biomol Chem 2008
18
Highly prevalent putative quadruplex sequence motifs in human DNA.
Alan K Todd, Matthew Johnston, Stephen Neidle. Nucleic Acids Res 2005
Alan K Todd, Matthew Johnston, Stephen Neidle. Nucleic Acids Res 2005
17
G-quadruplex, Friend or Foe: The Role of the G-quartet in Anticancer Strategies.
Josué Carvalho, Jean-Louis Mergny, Gilmar F Salgado, João A Queiroz, Carla Cruz. Trends Mol Med 2020
Josué Carvalho, Jean-Louis Mergny, Gilmar F Salgado, João A Queiroz, Carla Cruz. Trends Mol Med 2020
23
Inhibition of human telomerase by a G-quadruplex-interactive compound.
D Sun, B Thompson, B E Cathers, M Salazar, S M Kerwin, J O Trent, T C Jenkins, S Neidle, L H Hurley. J Med Chem 1997
D Sun, B Thompson, B E Cathers, M Salazar, S M Kerwin, J O Trent, T C Jenkins, S Neidle, L H Hurley. J Med Chem 1997
16
Crystal structure of parallel quadruplexes from human telomeric DNA.
Gary N Parkinson, Michael P H Lee, Stephen Neidle. Nature 2002
Gary N Parkinson, Michael P H Lee, Stephen Neidle. Nature 2002
16
G-quadruplexes in promoters throughout the human genome.
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2007
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2007
15
Re-evaluation of G-quadruplex propensity with G4Hunter.
Amina Bedrat, Laurent Lacroix, Jean-Louis Mergny. Nucleic Acids Res 2016
Amina Bedrat, Laurent Lacroix, Jean-Louis Mergny. Nucleic Acids Res 2016
15
Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization.
Attila Ambrus, Ding Chen, Jixun Dai, Roger A Jones, Danzhou Yang. Biochemistry 2005
Attila Ambrus, Ding Chen, Jixun Dai, Roger A Jones, Danzhou Yang. Biochemistry 2005
15
Solution structure of a 2:1 quindoline-c-MYC G-quadruplex: insights into G-quadruplex-interactive small molecule drug design.
Jixun Dai, Megan Carver, Laurence H Hurley, Danzhou Yang. J Am Chem Soc 2011
Jixun Dai, Megan Carver, Laurence H Hurley, Danzhou Yang. J Am Chem Soc 2011
14
The application of DNA and RNA G-quadruplexes to therapeutic medicines.
Gavin W Collie, Gary N Parkinson. Chem Soc Rev 2011
Gavin W Collie, Gary N Parkinson. Chem Soc Rev 2011
14
Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution.
Attila Ambrus, Ding Chen, Jixun Dai, Tiffanie Bialis, Roger A Jones, Danzhou Yang. Nucleic Acids Res 2006
Attila Ambrus, Ding Chen, Jixun Dai, Tiffanie Bialis, Roger A Jones, Danzhou Yang. Nucleic Acids Res 2006
14
G-Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy.
Rafael Del Villar-Guerra, John O Trent, Jonathan B Chaires. Angew Chem Int Ed Engl 2018
Rafael Del Villar-Guerra, John O Trent, Jonathan B Chaires. Angew Chem Int Ed Engl 2018
13
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.
Dinshaw J Patel, Anh Tuân Phan, Vitaly Kuryavyi. Nucleic Acids Res 2007
Dinshaw J Patel, Anh Tuân Phan, Vitaly Kuryavyi. Nucleic Acids Res 2007
13
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
Raphaël Rodriguez, Kyle M Miller, Josep V Forment, Charles R Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalce, Shankar Balasubramanian, Stephen P Jackson. Nat Chem Biol 2012
Raphaël Rodriguez, Kyle M Miller, Josep V Forment, Charles R Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalce, Shankar Balasubramanian, Stephen P Jackson. Nat Chem Biol 2012
13
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.
Hong Xu, Marco Di Antonio, Steven McKinney, Veena Mathew, Brandon Ho, Nigel J O'Neil, Nancy Dos Santos, Jennifer Silvester, Vivien Wei, Jessica Garcia,[...]. Nat Commun 2017
Hong Xu, Marco Di Antonio, Steven McKinney, Veena Mathew, Brandon Ho, Nigel J O'Neil, Nancy Dos Santos, Jennifer Silvester, Vivien Wei, Jessica Garcia,[...]. Nat Commun 2017
13
Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy.
Sefan Asamitsu, Shunsuke Obata, Zutao Yu, Toshikazu Bando, Hiroshi Sugiyama. Molecules 2019
Sefan Asamitsu, Shunsuke Obata, Zutao Yu, Toshikazu Bando, Hiroshi Sugiyama. Molecules 2019
13
G-Quadruplexes: Prediction, Characterization, and Biological Application.
Chun Kit Kwok, Catherine J Merrick. Trends Biotechnol 2017
Chun Kit Kwok, Catherine J Merrick. Trends Biotechnol 2017
13
Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Anh Tuân Phan, Vitaly Kuryavyi, Hai Yan Gaw, Dinshaw J Patel. Nat Chem Biol 2005
Anh Tuân Phan, Vitaly Kuryavyi, Hai Yan Gaw, Dinshaw J Patel. Nat Chem Biol 2005
13
Landscape of G-quadruplex DNA structural regions in breast cancer.
Robert Hänsel-Hertsch, Angela Simeone, Abigail Shea, Winnie W I Hui, Katherine G Zyner, Giovanni Marsico, Oscar M Rueda, Alejandra Bruna, Alistair Martin, Xiaoyun Zhang,[...]. Nat Genet 2020
Robert Hänsel-Hertsch, Angela Simeone, Abigail Shea, Winnie W I Hui, Katherine G Zyner, Giovanni Marsico, Oscar M Rueda, Alejandra Bruna, Alistair Martin, Xiaoyun Zhang,[...]. Nat Genet 2020
27
Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.
David R Calabrese, Xiang Chen, Elena C Leon, Snehal M Gaikwad, Zaw Phyo, William M Hewitt, Stephanie Alden, Thomas A Hilimire, Fahu He, Aleksandra M Michalowski,[...]. Nat Commun 2018
David R Calabrese, Xiang Chen, Elena C Leon, Snehal M Gaikwad, Zaw Phyo, William M Hewitt, Stephanie Alden, Thomas A Hilimire, Fahu He, Aleksandra M Michalowski,[...]. Nat Commun 2018
17
Single-molecule visualization of DNA G-quadruplex formation in live cells.
Marco Di Antonio, Aleks Ponjavic, Antanas Radzevičius, Rohan T Ranasinghe, Marco Catalano, Xiaoyun Zhang, Jiazhen Shen, Lisa-Maria Needham, Steven F Lee, David Klenerman,[...]. Nat Chem 2020
Marco Di Antonio, Aleks Ponjavic, Antanas Radzevičius, Rohan T Ranasinghe, Marco Catalano, Xiaoyun Zhang, Jiazhen Shen, Lisa-Maria Needham, Steven F Lee, David Klenerman,[...]. Nat Chem 2020
13
Methods for investigating G-quadruplex DNA/ligand interactions.
Pierre Murat, Yashveer Singh, Eric Defrancq. Chem Soc Rev 2011
Pierre Murat, Yashveer Singh, Eric Defrancq. Chem Soc Rev 2011
12
Visualization of RNA-Quadruplexes in Live Cells.
Aurélien Laguerre, Kyle Hukezalie, Pascale Winckler, Fares Katranji, Gaëtan Chanteloup, Marc Pirrotta, Jean-Marie Perrier-Cornet, Judy M Y Wong, David Monchaud. J Am Chem Soc 2015
Aurélien Laguerre, Kyle Hukezalie, Pascale Winckler, Fares Katranji, Gaëtan Chanteloup, Marc Pirrotta, Jean-Marie Perrier-Cornet, Judy M Y Wong, David Monchaud. J Am Chem Soc 2015
12
NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.
Jixun Dai, Ding Chen, Roger A Jones, Laurence H Hurley, Danzhou Yang. Nucleic Acids Res 2006
Jixun Dai, Ding Chen, Roger A Jones, Laurence H Hurley, Danzhou Yang. Nucleic Acids Res 2006
11
G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.
Susanna Cogoi, Luigi E Xodo. Nucleic Acids Res 2006
Susanna Cogoi, Luigi E Xodo. Nucleic Acids Res 2006
11
Fluorescence-based melting assays for studying quadruplex ligands.
Anne De Cian, Lionel Guittat, Markus Kaiser, Barbara Saccà, Samir Amrane, Anne Bourdoncle, Patrizia Alberti, Marie-Paule Teulade-Fichou, Laurent Lacroix, Jean-Louis Mergny. Methods 2007
Anne De Cian, Lionel Guittat, Markus Kaiser, Barbara Saccà, Samir Amrane, Anne Bourdoncle, Patrizia Alberti, Marie-Paule Teulade-Fichou, Laurent Lacroix, Jean-Louis Mergny. Methods 2007
11
Detection of G-quadruplex DNA in mammalian cells.
Alexander Henderson, Yuliang Wu, Yu Chuan Huang, Elizabeth A Chavez, Jesse Platt, F Brad Johnson, Robert M Brosh, Dipankar Sen, Peter M Lansdorp. Nucleic Acids Res 2014
Alexander Henderson, Yuliang Wu, Yu Chuan Huang, Elizabeth A Chavez, Jesse Platt, F Brad Johnson, Robert M Brosh, Dipankar Sen, Peter M Lansdorp. Nucleic Acids Res 2014
11
G-quadruplex structures: in vivo evidence and function.
Hans J Lipps, Daniela Rhodes. Trends Cell Biol 2009
Hans J Lipps, Daniela Rhodes. Trends Cell Biol 2009
10
A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres.
Raphaël Rodriguez, Sebastian Müller, Justin A Yeoman, Chantal Trentesaux, Jean-François Riou, Shankar Balasubramanian. J Am Chem Soc 2008
Raphaël Rodriguez, Sebastian Müller, Justin A Yeoman, Chantal Trentesaux, Jean-François Riou, Shankar Balasubramanian. J Am Chem Soc 2008
10
Highly efficient G-quadruplex recognition by bisquinolinium compounds.
Anne De Cian, Elsa Delemos, Jean-Louis Mergny, Marie-Paule Teulade-Fichou, David Monchaud. J Am Chem Soc 2007
Anne De Cian, Elsa Delemos, Jean-Louis Mergny, Marie-Paule Teulade-Fichou, David Monchaud. J Am Chem Soc 2007
10
Ligand Design to Acquire Specificity to Intended G-Quadruplex Structures.
Sefan Asamitsu, Toshikazu Bando, Hiroshi Sugiyama. Chemistry 2019
Sefan Asamitsu, Toshikazu Bando, Hiroshi Sugiyama. Chemistry 2019
14
Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3).
Wan Jun Chung, Brahim Heddi, Florian Hamon, Marie-Paule Teulade-Fichou, Anh Tuân Phan. Angew Chem Int Ed Engl 2014
Wan Jun Chung, Brahim Heddi, Florian Hamon, Marie-Paule Teulade-Fichou, Anh Tuân Phan. Angew Chem Int Ed Engl 2014
10
The interactions between a small molecule and G-quadruplexes are visualized by fluorescence lifetime imaging microscopy.
Arun Shivalingam, M Angeles Izquierdo, Alix Le Marois, Aurimas Vyšniauskas, Klaus Suhling, Marina K Kuimova, Ramon Vilar. Nat Commun 2015
Arun Shivalingam, M Angeles Izquierdo, Alix Le Marois, Aurimas Vyšniauskas, Klaus Suhling, Marina K Kuimova, Ramon Vilar. Nat Commun 2015
10
The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function.
Angelika M Burger, Fangping Dai, Christoph M Schultes, Anthony P Reszka, Michael J Moore, John A Double, Stephen Neidle. Cancer Res 2005
Angelika M Burger, Fangping Dai, Christoph M Schultes, Anthony P Reszka, Michael J Moore, John A Double, Stephen Neidle. Cancer Res 2005
10
G-quadruplexes and helicases.
Oscar Mendoza, Anne Bourdoncle, Jean-Baptiste Boulé, Robert M Brosh, Jean-Louis Mergny. Nucleic Acids Res 2016
Oscar Mendoza, Anne Bourdoncle, Jean-Baptiste Boulé, Robert M Brosh, Jean-Louis Mergny. Nucleic Acids Res 2016
10
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells.
Giulia Biffi, Marco Di Antonio, David Tannahill, Shankar Balasubramanian. Nat Chem 2014
Giulia Biffi, Marco Di Antonio, David Tannahill, Shankar Balasubramanian. Nat Chem 2014
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.