Stephen Neidle. J Med Chem 2016
Times Cited: 260
Times Cited: 260
Times Cited
Times Co-cited
Similarity
G-quadruplexes and their regulatory roles in biology.
Daniela Rhodes, Hans J Lipps. Nucleic Acids Res 2015
Daniela Rhodes, Hans J Lipps. Nucleic Acids Res 2015
38
High-throughput sequencing of DNA G-quadruplex structures in the human genome.
Vicki S Chambers, Giovanni Marsico, Jonathan M Boutell, Marco Di Antonio, Geoffrey P Smith, Shankar Balasubramanian. Nat Biotechnol 2015
Vicki S Chambers, Giovanni Marsico, Jonathan M Boutell, Marco Di Antonio, Geoffrey P Smith, Shankar Balasubramanian. Nat Biotechnol 2015
31
Quantitative visualization of DNA G-quadruplex structures in human cells.
Giulia Biffi, David Tannahill, John McCafferty, Shankar Balasubramanian. Nat Chem 2013
Giulia Biffi, David Tannahill, John McCafferty, Shankar Balasubramanian. Nat Chem 2013
31
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription.
Adam Siddiqui-Jain, Cory L Grand, David J Bearss, Laurence H Hurley. Proc Natl Acad Sci U S A 2002
Adam Siddiqui-Jain, Cory L Grand, David J Bearss, Laurence H Hurley. Proc Natl Acad Sci U S A 2002
29
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
Shankar Balasubramanian, Laurence H Hurley, Stephen Neidle. Nat Rev Drug Discov 2011
Shankar Balasubramanian, Laurence H Hurley, Stephen Neidle. Nat Rev Drug Discov 2011
28
Quadruplex DNA: sequence, topology and structure.
Sarah Burge, Gary N Parkinson, Pascale Hazel, Alan K Todd, Stephen Neidle. Nucleic Acids Res 2006
Sarah Burge, Gary N Parkinson, Pascale Hazel, Alan K Todd, Stephen Neidle. Nucleic Acids Res 2006
26
G-quadruplex structures mark human regulatory chromatin.
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
24
Prevalence of quadruplexes in the human genome.
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2005
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2005
23
DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential.
Robert Hänsel-Hertsch, Marco Di Antonio, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2017
Robert Hänsel-Hertsch, Marco Di Antonio, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2017
22
Re-evaluation of G-quadruplex propensity with G4Hunter.
Amina Bedrat, Laurent Lacroix, Jean-Louis Mergny. Nucleic Acids Res 2016
Amina Bedrat, Laurent Lacroix, Jean-Louis Mergny. Nucleic Acids Res 2016
20
DNA secondary structures: stability and function of G-quadruplex structures.
Matthew L Bochman, Katrin Paeschke, Virginia A Zakian. Nat Rev Genet 2012
Matthew L Bochman, Katrin Paeschke, Virginia A Zakian. Nat Rev Genet 2012
19
Crystal structure of parallel quadruplexes from human telomeric DNA.
Gary N Parkinson, Michael P H Lee, Stephen Neidle. Nature 2002
Gary N Parkinson, Michael P H Lee, Stephen Neidle. Nature 2002
17
16
G-quadruplexes in promoters throughout the human genome.
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2007
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2007
16
Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization.
Attila Ambrus, Ding Chen, Jixun Dai, Roger A Jones, Danzhou Yang. Biochemistry 2005
Attila Ambrus, Ding Chen, Jixun Dai, Roger A Jones, Danzhou Yang. Biochemistry 2005
16
Highly prevalent putative quadruplex sequence motifs in human DNA.
Alan K Todd, Matthew Johnston, Stephen Neidle. Nucleic Acids Res 2005
Alan K Todd, Matthew Johnston, Stephen Neidle. Nucleic Acids Res 2005
16
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.
Hong Xu, Marco Di Antonio, Steven McKinney, Veena Mathew, Brandon Ho, Nigel J O'Neil, Nancy Dos Santos, Jennifer Silvester, Vivien Wei, Jessica Garcia,[...]. Nat Commun 2017
Hong Xu, Marco Di Antonio, Steven McKinney, Veena Mathew, Brandon Ho, Nigel J O'Neil, Nancy Dos Santos, Jennifer Silvester, Vivien Wei, Jessica Garcia,[...]. Nat Commun 2017
16
The regulation and functions of DNA and RNA G-quadruplexes.
Dhaval Varshney, Jochen Spiegel, Katherine Zyner, David Tannahill, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2020
Dhaval Varshney, Jochen Spiegel, Katherine Zyner, David Tannahill, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2020
16
G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy.
Emanuela Ruggiero, Sara N Richter. Nucleic Acids Res 2018
Emanuela Ruggiero, Sara N Richter. Nucleic Acids Res 2018
15
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
Raphaël Rodriguez, Kyle M Miller, Josep V Forment, Charles R Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalce, Shankar Balasubramanian, Stephen P Jackson. Nat Chem Biol 2012
Raphaël Rodriguez, Kyle M Miller, Josep V Forment, Charles R Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalce, Shankar Balasubramanian, Stephen P Jackson. Nat Chem Biol 2012
15
Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy.
Sefan Asamitsu, Shunsuke Obata, Zutao Yu, Toshikazu Bando, Hiroshi Sugiyama. Molecules 2019
Sefan Asamitsu, Shunsuke Obata, Zutao Yu, Toshikazu Bando, Hiroshi Sugiyama. Molecules 2019
15
The Structure and Function of DNA G-Quadruplexes.
Jochen Spiegel, Santosh Adhikari, Shankar Balasubramanian. Trends Chem 2020
Jochen Spiegel, Santosh Adhikari, Shankar Balasubramanian. Trends Chem 2020
15
A hitchhiker's guide to G-quadruplex ligands.
David Monchaud, Marie-Paule Teulade-Fichou. Org Biomol Chem 2008
David Monchaud, Marie-Paule Teulade-Fichou. Org Biomol Chem 2008
14
Solution structure of a 2:1 quindoline-c-MYC G-quadruplex: insights into G-quadruplex-interactive small molecule drug design.
Jixun Dai, Megan Carver, Laurence H Hurley, Danzhou Yang. J Am Chem Soc 2011
Jixun Dai, Megan Carver, Laurence H Hurley, Danzhou Yang. J Am Chem Soc 2011
13
Inhibition of human telomerase by a G-quadruplex-interactive compound.
D Sun, B Thompson, B E Cathers, M Salazar, S M Kerwin, J O Trent, T C Jenkins, S Neidle, L H Hurley. J Med Chem 1997
D Sun, B Thompson, B E Cathers, M Salazar, S M Kerwin, J O Trent, T C Jenkins, S Neidle, L H Hurley. J Med Chem 1997
12
G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.
Susanna Cogoi, Luigi E Xodo. Nucleic Acids Res 2006
Susanna Cogoi, Luigi E Xodo. Nucleic Acids Res 2006
12
Fluorescence-based melting assays for studying quadruplex ligands.
Anne De Cian, Lionel Guittat, Markus Kaiser, Barbara Saccà, Samir Amrane, Anne Bourdoncle, Patrizia Alberti, Marie-Paule Teulade-Fichou, Laurent Lacroix, Jean-Louis Mergny. Methods 2007
Anne De Cian, Lionel Guittat, Markus Kaiser, Barbara Saccà, Samir Amrane, Anne Bourdoncle, Patrizia Alberti, Marie-Paule Teulade-Fichou, Laurent Lacroix, Jean-Louis Mergny. Methods 2007
12
The interactions between a small molecule and G-quadruplexes are visualized by fluorescence lifetime imaging microscopy.
Arun Shivalingam, M Angeles Izquierdo, Alix Le Marois, Aurimas Vyšniauskas, Klaus Suhling, Marina K Kuimova, Ramon Vilar. Nat Commun 2015
Arun Shivalingam, M Angeles Izquierdo, Alix Le Marois, Aurimas Vyšniauskas, Klaus Suhling, Marina K Kuimova, Ramon Vilar. Nat Commun 2015
12
Putative DNA quadruplex formation within the human c-kit oncogene.
Sarah Rankin, Anthony P Reszka, Julian Huppert, Mire Zloh, Gary N Parkinson, Alan K Todd, Sylvain Ladame, Shankar Balasubramanian, Stephen Neidle. J Am Chem Soc 2005
Sarah Rankin, Anthony P Reszka, Julian Huppert, Mire Zloh, Gary N Parkinson, Alan K Todd, Sylvain Ladame, Shankar Balasubramanian, Stephen Neidle. J Am Chem Soc 2005
11
G-quadruplex structures: in vivo evidence and function.
Hans J Lipps, Daniela Rhodes. Trends Cell Biol 2009
Hans J Lipps, Daniela Rhodes. Trends Cell Biol 2009
11
Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.
David R Calabrese, Xiang Chen, Elena C Leon, Snehal M Gaikwad, Zaw Phyo, William M Hewitt, Stephanie Alden, Thomas A Hilimire, Fahu He, Aleksandra M Michalowski,[...]. Nat Commun 2018
David R Calabrese, Xiang Chen, Elena C Leon, Snehal M Gaikwad, Zaw Phyo, William M Hewitt, Stephanie Alden, Thomas A Hilimire, Fahu He, Aleksandra M Michalowski,[...]. Nat Commun 2018
19
Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis.
D Sen, W Gilbert. Nature 1988
D Sen, W Gilbert. Nature 1988
11
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.
Dinshaw J Patel, Anh Tuân Phan, Vitaly Kuryavyi. Nucleic Acids Res 2007
Dinshaw J Patel, Anh Tuân Phan, Vitaly Kuryavyi. Nucleic Acids Res 2007
11
Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo.
Katrin Paeschke, Tomas Simonsson, Jan Postberg, Daniela Rhodes, Hans Joachim Lipps. Nat Struct Mol Biol 2005
Katrin Paeschke, Tomas Simonsson, Jan Postberg, Daniela Rhodes, Hans Joachim Lipps. Nat Struct Mol Biol 2005
11
Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex.
Y Wang, D J Patel. Structure 1993
Y Wang, D J Patel. Structure 1993
11
Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffold.
Kim Ngoc Luu, Anh Tuân Phan, Vitaly Kuryavyi, Laurent Lacroix, Dinshaw J Patel. J Am Chem Soc 2006
Kim Ngoc Luu, Anh Tuân Phan, Vitaly Kuryavyi, Laurent Lacroix, Dinshaw J Patel. J Am Chem Soc 2006
11
Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3).
Wan Jun Chung, Brahim Heddi, Florian Hamon, Marie-Paule Teulade-Fichou, Anh Tuân Phan. Angew Chem Int Ed Engl 2014
Wan Jun Chung, Brahim Heddi, Florian Hamon, Marie-Paule Teulade-Fichou, Anh Tuân Phan. Angew Chem Int Ed Engl 2014
11
Detection of G-quadruplex DNA in mammalian cells.
Alexander Henderson, Yuliang Wu, Yu Chuan Huang, Elizabeth A Chavez, Jesse Platt, F Brad Johnson, Robert M Brosh, Dipankar Sen, Peter M Lansdorp. Nucleic Acids Res 2014
Alexander Henderson, Yuliang Wu, Yu Chuan Huang, Elizabeth A Chavez, Jesse Platt, F Brad Johnson, Robert M Brosh, Dipankar Sen, Peter M Lansdorp. Nucleic Acids Res 2014
11
Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution.
Attila Ambrus, Ding Chen, Jixun Dai, Tiffanie Bialis, Roger A Jones, Danzhou Yang. Nucleic Acids Res 2006
Attila Ambrus, Ding Chen, Jixun Dai, Tiffanie Bialis, Roger A Jones, Danzhou Yang. Nucleic Acids Res 2006
10
Identification and characterization of nucleolin as a c-myc G-quadruplex-binding protein.
Verónica González, Kexiao Guo, Laurence Hurley, Daekyu Sun. J Biol Chem 2009
Verónica González, Kexiao Guo, Laurence Hurley, Daekyu Sun. J Biol Chem 2009
10
G-quadruplexes and helicases.
Oscar Mendoza, Anne Bourdoncle, Jean-Baptiste Boulé, Robert M Brosh, Jean-Louis Mergny. Nucleic Acids Res 2016
Oscar Mendoza, Anne Bourdoncle, Jean-Baptiste Boulé, Robert M Brosh, Jean-Louis Mergny. Nucleic Acids Res 2016
10
Visualization of RNA-Quadruplexes in Live Cells.
Aurélien Laguerre, Kyle Hukezalie, Pascale Winckler, Fares Katranji, Gaëtan Chanteloup, Marc Pirrotta, Jean-Marie Perrier-Cornet, Judy M Y Wong, David Monchaud. J Am Chem Soc 2015
Aurélien Laguerre, Kyle Hukezalie, Pascale Winckler, Fares Katranji, Gaëtan Chanteloup, Marc Pirrotta, Jean-Marie Perrier-Cornet, Judy M Y Wong, David Monchaud. J Am Chem Soc 2015
10
Highly efficient G-quadruplex recognition by bisquinolinium compounds.
Anne De Cian, Elsa Delemos, Jean-Louis Mergny, Marie-Paule Teulade-Fichou, David Monchaud. J Am Chem Soc 2007
Anne De Cian, Elsa Delemos, Jean-Louis Mergny, Marie-Paule Teulade-Fichou, David Monchaud. J Am Chem Soc 2007
10
Anticancer activity of CX-3543: a direct inhibitor of rRNA biogenesis.
Denis Drygin, Adam Siddiqui-Jain, Sean O'Brien, Michael Schwaebe, Amy Lin, Josh Bliesath, Caroline B Ho, Chris Proffitt, Katy Trent, Jeffrey P Whitten,[...]. Cancer Res 2009
Denis Drygin, Adam Siddiqui-Jain, Sean O'Brien, Michael Schwaebe, Amy Lin, Josh Bliesath, Caroline B Ho, Chris Proffitt, Katy Trent, Jeffrey P Whitten,[...]. Cancer Res 2009
10
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells.
Giulia Biffi, Marco Di Antonio, David Tannahill, Shankar Balasubramanian. Nat Chem 2014
Giulia Biffi, Marco Di Antonio, David Tannahill, Shankar Balasubramanian. Nat Chem 2014
9
9
Design of Modular G-quadruplex Ligands.
Ana Rita Duarte, Enrico Cadoni, Ana S Ressurreição, Rui Moreira, Alexandra Paulo. ChemMedChem 2018
Ana Rita Duarte, Enrico Cadoni, Ana S Ressurreição, Rui Moreira, Alexandra Paulo. ChemMedChem 2018
21
A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres.
Raphaël Rodriguez, Sebastian Müller, Justin A Yeoman, Chantal Trentesaux, Jean-François Riou, Shankar Balasubramanian. J Am Chem Soc 2008
Raphaël Rodriguez, Sebastian Müller, Justin A Yeoman, Chantal Trentesaux, Jean-François Riou, Shankar Balasubramanian. J Am Chem Soc 2008
9
The application of DNA and RNA G-quadruplexes to therapeutic medicines.
Gavin W Collie, Gary N Parkinson. Chem Soc Rev 2011
Gavin W Collie, Gary N Parkinson. Chem Soc Rev 2011
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.