A citation-based method for searching scientific literature

Shawn M Davidson, Thales Papagiannakopoulos, Benjamin A Olenchock, Julia E Heyman, Mark A Keibler, Alba Luengo, Matthew R Bauer, Abhishek K Jha, James P O'Brien, Kerry A Pierce, Dan Y Gui, Lucas B Sullivan, Thomas M Wasylenko, Lakshmipriya Subbaraj, Christopher R Chin, Gregory Stephanopolous, Bryan T Mott, Tyler Jacks, Clary B Clish, Matthew G Vander Heiden. Cell Metab 2016
Times Cited: 436







List of co-cited articles
1401 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Metabolic Heterogeneity in Human Lung Tumors.
Christopher T Hensley, Brandon Faubert, Qing Yuan, Naama Lev-Cohain, Eunsook Jin, Jiyeon Kim, Lei Jiang, Bookyung Ko, Rachael Skelton, Laurin Loudat,[...]. Cell 2016
568
39

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
38

Lactate Metabolism in Human Lung Tumors.
Brandon Faubert, Kevin Y Li, Ling Cai, Christopher T Hensley, Jiyeon Kim, Lauren G Zacharias, Chendong Yang, Quyen N Do, Sarah Doucette, Daniel Burguete,[...]. Cell 2017
537
29

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
26

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
Jaekyoung Son, Costas A Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M Perera, Cristina R Ferrone, Edouard Mullarky, Ng Shyh-Chang,[...]. Nature 2013
25

Glucose feeds the TCA cycle via circulating lactate.
Sheng Hui, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, Tannishtha Reya, Le Zhan, Jessie Yanxiang Guo,[...]. Nature 2017
576
23

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Jared R Mayers, Margaret E Torrence, Laura V Danai, Thales Papagiannakopoulos, Shawn M Davidson, Matthew R Bauer, Allison N Lau, Brian W Ji, Purushottam D Dixit, Aaron M Hosios,[...]. Science 2016
305
23

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
23

The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type.
Mariia O Yuneva, Teresa W M Fan, Thaddeus D Allen, Richard M Higashi, Dana V Ferraris, Takashi Tsukamoto, José M Matés, Francisco J Alonso, Chunmei Wang, Youngho Seo,[...]. Cell Metab 2012
421
21

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion.
Robert D Leone, Liang Zhao, Judson M Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L Arwood, Ian A Bettencourt, Chirag H Patel, Jiayu Wen,[...]. Science 2019
286
20

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.
Katherine Sellers, Matthew P Fox, Michael Bousamra, Stephen P Slone, Richard M Higashi, Donald M Miller, Yali Wang, Jun Yan, Mariia O Yuneva, Rahul Deshpande,[...]. J Clin Invest 2015
308
20

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
20

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
19

On the origin of cancer cells.
O WARBURG. Science 1956
18

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
Cosimo Commisso, Shawn M Davidson, Rengin G Soydaner-Azeloglu, Seth J Parker, Jurre J Kamphorst, Sean Hackett, Elda Grabocka, Michel Nofal, Jeffrey A Drebin, Craig B Thompson,[...]. Nature 2013
918
18

Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability.
Mark R Sullivan, Laura V Danai, Caroline A Lewis, Sze Ham Chan, Dan Y Gui, Tenzin Kunchok, Emily A Dennstedt, Matthew G Vander Heiden, Alexander Muir. Elife 2019
161
17

Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.
Jason R Cantor, Monther Abu-Remaileh, Naama Kanarek, Elizaveta Freinkman, Xin Gao, Abner Louissaint, Caroline A Lewis, David M Sabatini. Cell 2017
189
17

Targeting Metabolism for Cancer Therapy.
Alba Luengo, Dan Y Gui, Matthew G Vander Heiden. Cell Chem Biol 2017
385
15

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.
Saverio Tardito, Anaïs Oudin, Shafiq U Ahmed, Fred Fack, Olivier Keunen, Liang Zheng, Hrvoje Miletic, Per Øystein Sakariassen, Adam Weinstock, Allon Wagner,[...]. Nat Cell Biol 2015
293
15

Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein.
Jurre J Kamphorst, Michel Nofal, Cosimo Commisso, Sean R Hackett, Wenyun Lu, Elda Grabocka, Matthew G Vander Heiden, George Miller, Jeffrey A Drebin, Dafna Bar-Sagi,[...]. Cancer Res 2015
435
15

From Krebs to clinic: glutamine metabolism to cancer therapy.
Brian J Altman, Zachary E Stine, Chi V Dang. Nat Rev Cancer 2016
764
15

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Haoqiang Ying, Alec C Kimmelman, Costas A Lyssiotis, Sujun Hua, Gerald C Chu, Eliot Fletcher-Sananikone, Jason W Locasale, Jaekyoung Son, Hailei Zhang, Jonathan L Coloff,[...]. Cell 2012
15

Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Matt I Gross, Susan D Demo, Jennifer B Dennison, Lijing Chen, Tania Chernov-Rogan, Bindu Goyal, Julie R Janes, Guy J Laidig, Evan R Lewis, Jim Li,[...]. Mol Cancer Ther 2014
541
15

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.
Cristovão M Sousa, Douglas E Biancur, Xiaoxu Wang, Christopher J Halbrook, Mara H Sherman, Li Zhang, Daniel Kremer, Rosa F Hwang, Agnes K Witkiewicz, Haoqiang Ying,[...]. Nature 2016
548
14

Improving the metabolic fidelity of cancer models with a physiological cell culture medium.
Johan Vande Voorde, Tobias Ackermann, Nadja Pfetzer, David Sumpton, Gillian Mackay, Gabriela Kalna, Colin Nixon, Karen Blyth, Eyal Gottlieb, Saverio Tardito. Sci Adv 2019
108
14

Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.
Rodrigo Romero, Volkan I Sayin, Shawn M Davidson, Matthew R Bauer, Simranjit X Singh, Sarah E LeBoeuf, Triantafyllia R Karakousi, Donald C Ellis, Arjun Bhutkar, Francisco J Sánchez-Rivera,[...]. Nat Med 2017
286
14

Metabolic reprogramming and cancer progression.
Brandon Faubert, Ashley Solmonson, Ralph J DeBerardinis. Science 2020
342
14

Understanding the Intersections between Metabolism and Cancer Biology.
Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
939
14

Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Oliver D K Maddocks, Dimitris Athineos, Eric C Cheung, Pearl Lee, Tong Zhang, Niels J F van den Broek, Gillian M Mackay, Christiaan F Labuschagne, David Gay, Flore Kruiswijk,[...]. Nature 2017
244
14

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
David R Wise, Ralph J DeBerardinis, Anthony Mancuso, Nabil Sayed, Xiao-Yong Zhang, Harla K Pfeiffer, Ilana Nissim, Evgueni Daikhin, Marc Yudkoff, Steven B McMahon,[...]. Proc Natl Acad Sci U S A 2008
14

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.
Christian M Metallo, Paulo A Gameiro, Eric L Bell, Katherine R Mattaini, Juanjuan Yang, Karsten Hiller, Christopher M Jewell, Zachary R Johnson, Darrell J Irvine, Leonard Guarente,[...]. Nature 2011
14

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism.
Douglas E Biancur, Joao A Paulo, Beata Małachowska, Maria Quiles Del Rey, Cristovão M Sousa, Xiaoxu Wang, Albert S W Sohn, Gerald C Chu, Steven P Gygi, J Wade Harper,[...]. Nat Commun 2017
141
13


Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition.
Bryan Ngo, Eugenie Kim, Victoria Osorio-Vasquez, Sophia Doll, Sophia Bustraan, Roger J Liang, Alba Luengo, Shawn M Davidson, Ahmed Ali, Gino B Ferraro,[...]. Cancer Discov 2020
64
18

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.
Pierre Sonveaux, Frédérique Végran, Thies Schroeder, Melanie C Wergin, Julien Verrax, Zahid N Rabbani, Christophe J De Saedeleer, Kelly M Kennedy, Caroline Diepart, Bénédicte F Jordan,[...]. J Clin Invest 2008
12

Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition.
Alexander Muir, Laura V Danai, Dan Y Gui, Chiara Y Waingarten, Caroline A Lewis, Matthew G Vander Heiden. Elife 2017
148
12

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
Jason W Locasale, Alexandra R Grassian, Tamar Melman, Costas A Lyssiotis, Katherine R Mattaini, Adam J Bass, Gregory Heffron, Christian M Metallo, Taru Muranen, Hadar Sharfi,[...]. Nat Genet 2011
722
12

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation.
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
11

THE METABOLISM OF TUMORS IN THE BODY.
O Warburg, F Wind, E Negelein. J Gen Physiol 1927
11

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.
Jiyeon Kim, Zeping Hu, Ling Cai, Kailong Li, Eunhee Choi, Brandon Faubert, Divya Bezwada, Jaime Rodriguez-Canales, Pamela Villalobos, Yu-Fen Lin,[...]. Nature 2017
134
11

Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting.
Mark R Sullivan, Katherine R Mattaini, Emily A Dennstedt, Anna A Nguyen, Sharanya Sivanand, Montana F Reilly, Katrina Meeth, Alexander Muir, Alicia M Darnell, Marcus W Bosenberg,[...]. Cell Metab 2019
94
11

Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis.
Stefan Christen, Doriane Lorendeau, Roberta Schmieder, Dorien Broekaert, Kristine Metzger, Koen Veys, Ilaria Elia, Joerg Martin Buescher, Martin Franz Orth, Shawn Michael Davidson,[...]. Cell Rep 2016
135
11

Glutaminolysis: A Hallmark of Cancer Metabolism.
Lifeng Yang, Sriram Venneti, Deepak Nagrath. Annu Rev Biomed Eng 2017
249
11

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells.
Tzuling Cheng, Jessica Sudderth, Chendong Yang, Andrew R Mullen, Eunsook S Jin, José M Matés, Ralph J DeBerardinis. Proc Natl Acad Sci U S A 2011
323
11

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.
Kıvanç Birsoy, Tim Wang, Walter W Chen, Elizaveta Freinkman, Monther Abu-Remaileh, David M Sabatini. Cell 2015
642
11

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.
Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang, Yun-Sil Lee, Kayoko Kita, Takafumi Ochi, Karen I Zeller, Angelo M De Marzo, Jennifer E Van Eyk, Joshua T Mendell,[...]. Nature 2009
11

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
10

Quantitative Fluxomics of Circulating Metabolites.
Sheng Hui, Alexis J Cowan, Xianfeng Zeng, Lifeng Yang, Tara TeSlaa, Xiaoxuan Li, Caroline Bartman, Zhaoyue Zhang, Cholsoon Jang, Lin Wang,[...]. Cell Metab 2020
52
19

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Richard Possemato, Kevin M Marks, Yoav D Shaul, Michael E Pacold, Dohoon Kim, Kıvanç Birsoy, Shalini Sethumadhavan, Hin-Koon Woo, Hyun G Jang, Abhishek K Jha,[...]. Nature 2011
10

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.
Dan Y Gui, Lucas B Sullivan, Alba Luengo, Aaron M Hosios, Lauren N Bush, Nadege Gitego, Shawn M Davidson, Elizaveta Freinkman, Craig J Thomas, Matthew G Vander Heiden. Cell Metab 2016
178
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.