Kristen R Ryan, Oksana Sirenko, Fred Parham, Jui-Hua Hsieh, Evan F Cromwell, Raymond R Tice, Mamta Behl. Neurotoxicology 2016
Times Cited: 83
Times Cited: 83
Times Cited
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Evaluation of a human neurite growth assay as specific screen for developmental neurotoxicants.
Anne K Krug, Nina V Balmer, Florian Matt, Felix Schönenberger, Dorit Merhof, Marcel Leist. Arch Toxicol 2013
Anne K Krug, Nina V Balmer, Florian Matt, Felix Schönenberger, Dorit Merhof, Marcel Leist. Arch Toxicol 2013
26
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.
Anna Bal-Price, Kevin M Crofton, Marcel Leist, Sandra Allen, Michael Arand, Timo Buetler, Nathalie Delrue, Rex E FitzGerald, Thomas Hartung, Tuula Heinonen,[...]. Arch Toxicol 2015
Anna Bal-Price, Kevin M Crofton, Marcel Leist, Sandra Allen, Michael Arand, Timo Buetler, Nathalie Delrue, Rex E FitzGerald, Thomas Hartung, Tuula Heinonen,[...]. Arch Toxicol 2015
21
Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes.
Ying Pei, Jun Peng, Mamta Behl, Nisha S Sipes, Keith R Shockley, Mahendra S Rao, Raymond R Tice, Xianmin Zeng. Brain Res 2016
Ying Pei, Jun Peng, Mamta Behl, Nisha S Sipes, Keith R Shockley, Mahendra S Rao, Raymond R Tice, Xianmin Zeng. Brain Res 2016
22
Neurobehavioural effects of developmental toxicity.
Philippe Grandjean, Philip J Landrigan. Lancet Neurol 2014
Philippe Grandjean, Philip J Landrigan. Lancet Neurol 2014
20
Developmental neurotoxicity testing in vitro: models for assessing chemical effects on neurite outgrowth.
Nicholas M Radio, William R Mundy. Neurotoxicology 2008
Nicholas M Radio, William R Mundy. Neurotoxicology 2008
20
Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.
Michael Aschner, Sandra Ceccatelli, Mardas Daneshian, Ellen Fritsche, Nina Hasiwa, Thomas Hartung, Helena T Hogberg, Marcel Leist, Abby Li, William R Mundi,[...]. ALTEX 2017
Michael Aschner, Sandra Ceccatelli, Mardas Daneshian, Ellen Fritsche, Nina Hasiwa, Thomas Hartung, Helena T Hogberg, Marcel Leist, Abby Li, William R Mundi,[...]. ALTEX 2017
20
Developmental neurotoxicity testing: a path forward.
Kevin M Crofton, William R Mundy, Timothy J Shafer. Congenit Anom (Kyoto) 2012
Kevin M Crofton, William R Mundy, Timothy J Shafer. Congenit Anom (Kyoto) 2012
22
Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures.
Nina V Stiegler, Anne K Krug, Florian Matt, Marcel Leist. Toxicol Sci 2011
Nina V Stiegler, Anne K Krug, Florian Matt, Marcel Leist. Toxicol Sci 2011
19
Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity.
Anna Bal-Price, Helena T Hogberg, Kevin M Crofton, Mardas Daneshian, Rex E FitzGerald, Ellen Fritsche, Tuula Heinonen, Susanne Hougaard Bennekou, Stefanie Klima, Aldert H Piersma,[...]. ALTEX 2018
Anna Bal-Price, Helena T Hogberg, Kevin M Crofton, Mardas Daneshian, Rex E FitzGerald, Ellen Fritsche, Tuula Heinonen, Susanne Hougaard Bennekou, Stefanie Klima, Aldert H Piersma,[...]. ALTEX 2018
19
18
Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation.
Anna K Bal-Price, Sandra Coecke, Lucio Costa, Kevin M Crofton, Ellen Fritsche, Alan Goldberg, Philippe Grandjean, Pamela J Lein, Abby Li, Roberto Lucchini,[...]. ALTEX 2012
Anna K Bal-Price, Sandra Coecke, Lucio Costa, Kevin M Crofton, Ellen Fritsche, Alan Goldberg, Philippe Grandjean, Pamela J Lein, Abby Li, Roberto Lucchini,[...]. ALTEX 2012
19
Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals.
Kevin M Crofton, William R Mundy, Pamela J Lein, Anna Bal-Price, Sandra Coecke, Andrea E M Seiler, Holger Knaut, Leonora Buzanska, Alan Goldberg. ALTEX 2011
Kevin M Crofton, William R Mundy, Pamela J Lein, Anna Bal-Price, Sandra Coecke, Andrea E M Seiler, Holger Knaut, Leonora Buzanska, Alan Goldberg. ALTEX 2011
18
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes.
Ellen Fritsche, Philippe Grandjean, Kevin M Crofton, Michael Aschner, Alan Goldberg, Tuula Heinonen, Ellen V S Hessel, Helena T Hogberg, Susanne Hougaard Bennekou, Pamela J Lein,[...]. Toxicol Appl Pharmacol 2018
Ellen Fritsche, Philippe Grandjean, Kevin M Crofton, Michael Aschner, Alan Goldberg, Tuula Heinonen, Ellen V S Hessel, Helena T Hogberg, Susanne Hougaard Bennekou, Pamela J Lein,[...]. Toxicol Appl Pharmacol 2018
20
Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells.
Heather E Wheeler, Claudia Wing, Shannon M Delaney, Masaaki Komatsu, M Eileen Dolan. PLoS One 2015
Heather E Wheeler, Claudia Wing, Shannon M Delaney, Masaaki Komatsu, M Eileen Dolan. PLoS One 2015
20
Testing for developmental neurotoxicity using a battery of in vitro assays for key cellular events in neurodevelopment.
Joshua A Harrill, Theresa Freudenrich, Kathleen Wallace, Kenneth Ball, Timothy J Shafer, William R Mundy. Toxicol Appl Pharmacol 2018
Joshua A Harrill, Theresa Freudenrich, Kathleen Wallace, Kenneth Ball, Timothy J Shafer, William R Mundy. Toxicol Appl Pharmacol 2018
38
Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities.
Lena Smirnova, Helena T Hogberg, Marcel Leist, Thomas Hartung. ALTEX 2014
Lena Smirnova, Helena T Hogberg, Marcel Leist, Thomas Hartung. ALTEX 2014
15
Developmental neurotoxicity guideline study: issues with methodology, evaluation and regulation.
Ryozo Tsuji, Kevin M Crofton. Congenit Anom (Kyoto) 2012
Ryozo Tsuji, Kevin M Crofton. Congenit Anom (Kyoto) 2012
23
From the Cover: Developmental Neurotoxicants Disrupt Activity in Cortical Networks on Microelectrode Arrays: Results of Screening 86 Compounds During Neural Network Formation.
Christopher L Frank, Jasmine P Brown, Kathleen Wallace, William R Mundy, Timothy J Shafer. Toxicol Sci 2017
Christopher L Frank, Jasmine P Brown, Kathleen Wallace, William R Mundy, Timothy J Shafer. Toxicol Sci 2017
34
Use of high content image analysis to detect chemical-induced changes in synaptogenesis in vitro.
Joshua A Harrill, Brian L Robinette, William R Mundy. Toxicol In Vitro 2011
Joshua A Harrill, Brian L Robinette, William R Mundy. Toxicol In Vitro 2011
15
Comparative human and rat neurospheres reveal species differences in chemical effects on neurodevelopmental key events.
Jenny Baumann, Kathrin Gassmann, Stefan Masjosthusmann, Denise DeBoer, Farina Bendt, Susanne Giersiefer, Ellen Fritsche. Arch Toxicol 2016
Jenny Baumann, Kathrin Gassmann, Stefan Masjosthusmann, Denise DeBoer, Farina Bendt, Susanne Giersiefer, Ellen Fritsche. Arch Toxicol 2016
23
OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes.
Ellen Fritsche, Kevin M Crofton, Antonio F Hernandez, Susanne Hougaard Bennekou, Marcel Leist, Anna Bal-Price, Elissa Reaves, Martin F Wilks, Andrea Terron, Roland Solecki,[...]. ALTEX 2017
Ellen Fritsche, Kevin M Crofton, Antonio F Hernandez, Susanne Hougaard Bennekou, Marcel Leist, Anna Bal-Price, Elissa Reaves, Martin F Wilks, Andrea Terron, Roland Solecki,[...]. ALTEX 2017
21
In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities.
Béla Z Schmidt, Martin Lehmann, Simon Gutbier, Erastus Nembo, Sabrina Noel, Lena Smirnova, Anna Forsby, Jürgen Hescheler, Hasan X Avci, Thomas Hartung,[...]. Arch Toxicol 2017
Béla Z Schmidt, Martin Lehmann, Simon Gutbier, Erastus Nembo, Sabrina Noel, Lena Smirnova, Anna Forsby, Jürgen Hescheler, Hasan X Avci, Thomas Hartung,[...]. Arch Toxicol 2017
13
Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity.
Mamta Behl, Jui-Hua Hsieh, Timothy J Shafer, William R Mundy, Julie R Rice, Windy A Boyd, Jonathan H Freedman, E Sidney Hunter, Kimberly A Jarema, Stephanie Padilla,[...]. Neurotoxicol Teratol 2015
Mamta Behl, Jui-Hua Hsieh, Timothy J Shafer, William R Mundy, Julie R Rice, Windy A Boyd, Jonathan H Freedman, E Sidney Hunter, Kimberly A Jarema, Stephanie Padilla,[...]. Neurotoxicol Teratol 2015
12
Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies.
Sandra Coecke, Alan M Goldberg, Sandra Allen, Leonora Buzanska, Gemma Calamandrei, Kevin Crofton, Lars Hareng, Thomas Hartung, Holger Knaut, Paul Honegger,[...]. Environ Health Perspect 2007
Sandra Coecke, Alan M Goldberg, Sandra Allen, Leonora Buzanska, Gemma Calamandrei, Kevin Crofton, Lars Hareng, Thomas Hartung, Holger Knaut, Paul Honegger,[...]. Environ Health Perspect 2007
12
Expanding the test set: Chemicals with potential to disrupt mammalian brain development.
William R Mundy, Stephanie Padilla, Joseph M Breier, Kevin M Crofton, Mary E Gilbert, David W Herr, Karl F Jensen, Nicholas M Radio, Kathleen C Raffaele, Kelly Schumacher,[...]. Neurotoxicol Teratol 2015
William R Mundy, Stephanie Padilla, Joseph M Breier, Kevin M Crofton, Mary E Gilbert, David W Herr, Karl F Jensen, Nicholas M Radio, Kathleen C Raffaele, Kelly Schumacher,[...]. Neurotoxicol Teratol 2015
18
Stem Cell-Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants.
Lisa Hoelting, Stefanie Klima, Christiaan Karreman, Marianna Grinberg, Johannes Meisig, Margit Henry, Tamara Rotshteyn, Jörg Rahnenführer, Nils Blüthgen, Agapios Sachinidis,[...]. Stem Cells Transl Med 2016
Lisa Hoelting, Stefanie Klima, Christiaan Karreman, Marianna Grinberg, Johannes Meisig, Margit Henry, Tamara Rotshteyn, Jörg Rahnenführer, Nils Blüthgen, Agapios Sachinidis,[...]. Stem Cells Transl Med 2016
22
Multiparametric High Content Analysis for assessment of neurotoxicity in differentiated neuronal cell lines and human embryonic stem cell-derived neurons.
Melinda S Wilson, James R Graham, Andrew J Ball. Neurotoxicology 2014
Melinda S Wilson, James R Graham, Andrew J Ball. Neurotoxicology 2014
34
Use of high content image analyses to detect chemical-mediated effects on neurite sub-populations in primary rat cortical neurons.
Joshua A Harrill, Brian L Robinette, Theresa Freudenrich, William R Mundy. Neurotoxicology 2013
Joshua A Harrill, Brian L Robinette, Theresa Freudenrich, William R Mundy. Neurotoxicology 2013
22
Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka. Cell 2007
Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka. Cell 2007
12
Development of a pluripotent stem cell derived neuronal model to identify chemically induced pathway perturbations in relation to neurotoxicity: effects of CREB pathway inhibition.
Francesca Pistollato, Jochem Louisse, Bibiana Scelfo, Milena Mennecozzi, Benedetta Accordi, Giuseppe Basso, John Antonydas Gaspar, Dimitra Zagoura, Manuela Barilari, Taina Palosaari,[...]. Toxicol Appl Pharmacol 2014
Francesca Pistollato, Jochem Louisse, Bibiana Scelfo, Milena Mennecozzi, Benedetta Accordi, Giuseppe Basso, John Antonydas Gaspar, Dimitra Zagoura, Manuela Barilari, Taina Palosaari,[...]. Toxicol Appl Pharmacol 2014
45
A high-throughput approach to identify specific neurotoxicants/ developmental toxicants in human neuronal cell function assays.
Johannes Delp, Simon Gutbier, Stefanie Klima, Lisa Hoelting, Kevin Pinto-Gil, Jui-Hua Hsieh, Michael Aichem, Karsten Klein, Falk Schreiber, Raymond R Tice,[...]. ALTEX 2018
Johannes Delp, Simon Gutbier, Stefanie Klima, Lisa Hoelting, Kevin Pinto-Gil, Jui-Hua Hsieh, Michael Aichem, Karsten Klein, Falk Schreiber, Raymond R Tice,[...]. ALTEX 2018
35
Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment.
Gerald T Ankley, Richard S Bennett, Russell J Erickson, Dale J Hoff, Michael W Hornung, Rodney D Johnson, David R Mount, John W Nichols, Christine L Russom, Patricia K Schmieder,[...]. Environ Toxicol Chem 2010
Gerald T Ankley, Richard S Bennett, Russell J Erickson, Dale J Hoff, Michael W Hornung, Rodney D Johnson, David R Mount, John W Nichols, Christine L Russom, Patricia K Schmieder,[...]. Environ Toxicol Chem 2010
10
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.
Anne K Krug, Raivo Kolde, John A Gaspar, Eugen Rempel, Nina V Balmer, Kesavan Meganathan, Kinga Vojnits, Mathurin Baquié, Tanja Waldmann, Roberto Ensenat-Waser,[...]. Arch Toxicol 2013
Anne K Krug, Raivo Kolde, John A Gaspar, Eugen Rempel, Nina V Balmer, Kesavan Meganathan, Kinga Vojnits, Mathurin Baquié, Tanja Waldmann, Roberto Ensenat-Waser,[...]. Arch Toxicol 2013
10
In vitro and other alternative approaches to developmental neurotoxicity testing (DNT).
Pamela Lein, Ellen Silbergeld, Paul Locke, Alan M Goldberg. Environ Toxicol Pharmacol 2005
Pamela Lein, Ellen Silbergeld, Paul Locke, Alan M Goldberg. Environ Toxicol Pharmacol 2005
11
Compound selection for in vitro modeling of developmental neurotoxicity.
Suzanne Kadereit, Bastian Zimmer, Christoph van Thriel, Jan G Hengstler, Marcel Leist. Front Biosci (Landmark Ed) 2012
Suzanne Kadereit, Bastian Zimmer, Christoph van Thriel, Jan G Hengstler, Marcel Leist. Front Biosci (Landmark Ed) 2012
15
Sensitivity of neuroprogenitor cells to chemical-induced apoptosis using a multiplexed assay suitable for high-throughput screening.
Ingrid Druwe, Theresa M Freudenrich, Kathleen Wallace, Timothy J Shafer, William R Mundy. Toxicology 2015
Ingrid Druwe, Theresa M Freudenrich, Kathleen Wallace, Timothy J Shafer, William R Mundy. Toxicology 2015
36
Cerebral organoids model human brain development and microcephaly.
Madeline A Lancaster, Magdalena Renner, Carol-Anne Martin, Daniel Wenzel, Louise S Bicknell, Matthew E Hurles, Tessa Homfray, Josef M Penninger, Andrew P Jackson, Juergen A Knoblich. Nature 2013
Madeline A Lancaster, Magdalena Renner, Carol-Anne Martin, Daniel Wenzel, Louise S Bicknell, Matthew E Hurles, Tessa Homfray, Josef M Penninger, Andrew P Jackson, Juergen A Knoblich. Nature 2013
10
Omnisphero: a high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro.
Martin R Schmuck, Thomas Temme, Katharina Dach, Denise de Boer, Marta Barenys, Farina Bendt, Axel Mosig, Ellen Fritsche. Arch Toxicol 2017
Martin R Schmuck, Thomas Temme, Katharina Dach, Denise de Boer, Marta Barenys, Farina Bendt, Axel Mosig, Ellen Fritsche. Arch Toxicol 2017
20
Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods.
Anna Bal-Price, Francesca Pistollato, Magdalini Sachana, Stephanie K Bopp, Sharon Munn, Andrew Worth. Toxicol Appl Pharmacol 2018
Anna Bal-Price, Francesca Pistollato, Magdalini Sachana, Stephanie K Bopp, Sharon Munn, Andrew Worth. Toxicol Appl Pharmacol 2018
13
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling.
Stuart M Chambers, Christopher A Fasano, Eirini P Papapetrou, Mark Tomishima, Michel Sadelain, Lorenz Studer. Nat Biotechnol 2009
Stuart M Chambers, Christopher A Fasano, Eirini P Papapetrou, Mark Tomishima, Michel Sadelain, Lorenz Studer. Nat Biotechnol 2009
10
Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome.
Nina V Balmer, Matthias K Weng, Bastian Zimmer, Violeta N Ivanova, Stuart M Chambers, Elena Nikolaeva, Smita Jagtap, Agapios Sachinidis, Jürgen Hescheler, Tanja Waldmann,[...]. Hum Mol Genet 2012
Nina V Balmer, Matthias K Weng, Bastian Zimmer, Violeta N Ivanova, Stuart M Chambers, Elena Nikolaeva, Smita Jagtap, Agapios Sachinidis, Jürgen Hescheler, Tanja Waldmann,[...]. Hum Mol Genet 2012
11
Quantitative assessment of neurite outgrowth in human embryonic stem cell-derived hN2 cells using automated high-content image analysis.
Joshua A Harrill, Theresa M Freudenrich, Dave W Machacek, Steven L Stice, William R Mundy. Neurotoxicology 2010
Joshua A Harrill, Theresa M Freudenrich, Dave W Machacek, Steven L Stice, William R Mundy. Neurotoxicology 2010
10
Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening.
Nicholas M Radio, Joseph M Breier, Timothy J Shafer, William R Mundy. Toxicol Sci 2008
Nicholas M Radio, Joseph M Breier, Timothy J Shafer, William R Mundy. Toxicol Sci 2008
9
High-content assays for hepatotoxicity using induced pluripotent stem cell-derived cells.
Oksana Sirenko, Jayne Hesley, Ivan Rusyn, Evan F Cromwell. Assay Drug Dev Technol 2014
Oksana Sirenko, Jayne Hesley, Ivan Rusyn, Evan F Cromwell. Assay Drug Dev Technol 2014
9
Phenotypic Characterization of Toxic Compound Effects on Liver Spheroids Derived from iPSC Using Confocal Imaging and Three-Dimensional Image Analysis.
Oksana Sirenko, Michael K Hancock, Jayne Hesley, Dihui Hong, Avrum Cohen, Jason Gentry, Coby B Carlson, David A Mann. Assay Drug Dev Technol 2016
Oksana Sirenko, Michael K Hancock, Jayne Hesley, Dihui Hong, Avrum Cohen, Jason Gentry, Coby B Carlson, David A Mann. Assay Drug Dev Technol 2016
13
Editor's Highlight: Evaluation of a Microelectrode Array-Based Assay for Neural Network Ontogeny Using Training Set Chemicals.
Jasmine P Brown, Diana Hall, Christopher L Frank, Kathleen Wallace, William R Mundy, Timothy J Shafer. Toxicol Sci 2016
Jasmine P Brown, Diana Hall, Christopher L Frank, Kathleen Wallace, William R Mundy, Timothy J Shafer. Toxicol Sci 2016
26
Improving the human hazard characterization of chemicals: a Tox21 update.
Raymond R Tice, Christopher P Austin, Robert J Kavlock, John R Bucher. Environ Health Perspect 2013
Raymond R Tice, Christopher P Austin, Robert J Kavlock, John R Bucher. Environ Health Perspect 2013
8
Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells.
Bastian Zimmer, Gabsang Lee, Nina V Balmer, Kesavan Meganathan, Agapios Sachinidis, Lorenz Studer, Marcel Leist. Environ Health Perspect 2012
Bastian Zimmer, Gabsang Lee, Nina V Balmer, Kesavan Meganathan, Agapios Sachinidis, Lorenz Studer, Marcel Leist. Environ Health Perspect 2012
10
In vitro developmental neurotoxicity (DNT) testing: relevant models and endpoints.
Anna K Bal-Price, Helena T Hogberg, Leonora Buzanska, Petros Lenas, Erwin van Vliet, Thomas Hartung. Neurotoxicology 2010
Anna K Bal-Price, Helena T Hogberg, Leonora Buzanska, Petros Lenas, Erwin van Vliet, Thomas Hartung. Neurotoxicology 2010
10
Putative adverse outcome pathways relevant to neurotoxicity.
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J Lein, Jochem Louisse,[...]. Crit Rev Toxicol 2015
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J Lein, Jochem Louisse,[...]. Crit Rev Toxicol 2015
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.