Ivan Zanoni, Yunhao Tan, Marco Di Gioia, Achille Broggi, Jianbin Ruan, Jianjin Shi, Carlos A Donado, Feng Shao, Hao Wu, James R Springstead, Jonathan C Kagan. Science 2016
Times Cited: 256
Times Cited: 256
Times Cited
Times Co-cited
Similarity
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
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The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.
Charles L Evavold, Jianbin Ruan, Yunhao Tan, Shiyu Xia, Hao Wu, Jonathan C Kagan. Immunity 2018
Charles L Evavold, Jianbin Ruan, Yunhao Tan, Shiyu Xia, Hao Wu, Jonathan C Kagan. Immunity 2018
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Non-canonical inflammasome activation targets caspase-11.
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
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Inflammatory caspases are innate immune receptors for intracellular LPS.
Jianjin Shi, Yue Zhao, Yupeng Wang, Wenqing Gao, Jingjin Ding, Peng Li, Liyan Hu, Feng Shao. Nature 2014
Jianjin Shi, Yue Zhao, Yupeng Wang, Wenqing Gao, Jingjin Ding, Peng Li, Liyan Hu, Feng Shao. Nature 2014
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Pore-forming activity and structural autoinhibition of the gasdermin family.
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
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Noncanonical inflammasome activation by intracellular LPS independent of TLR4.
Nobuhiko Kayagaki, Michael T Wong, Irma B Stowe, Sree Ranjani Ramani, Lino C Gonzalez, Sachiko Akashi-Takamura, Kensuke Miyake, Juan Zhang, Wyne P Lee, Artur Muszyński,[...]. Science 2013
Nobuhiko Kayagaki, Michael T Wong, Irma B Stowe, Sree Ranjani Ramani, Lino C Gonzalez, Sachiko Akashi-Takamura, Kensuke Miyake, Juan Zhang, Wyne P Lee, Artur Muszyński,[...]. Science 2013
35
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
Wan-ting He, Haoqiang Wan, Lichen Hu, Pengda Chen, Xin Wang, Zhe Huang, Zhang-Hua Yang, Chuan-Qi Zhong, Jiahuai Han. Cell Res 2015
Wan-ting He, Haoqiang Wan, Lichen Hu, Pengda Chen, Xin Wang, Zhe Huang, Zhang-Hua Yang, Chuan-Qi Zhong, Jiahuai Han. Cell Res 2015
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ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation.
Sebastian Rühl, Kateryna Shkarina, Benjamin Demarco, Rosalie Heilig, José Carlos Santos, Petr Broz. Science 2018
Sebastian Rühl, Kateryna Shkarina, Benjamin Demarco, Rosalie Heilig, José Carlos Santos, Petr Broz. Science 2018
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Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin.
Yupeng Wang, Wenqing Gao, Xuyan Shi, Jingjin Ding, Wang Liu, Huabin He, Kun Wang, Feng Shao. Nature 2017
Yupeng Wang, Wenqing Gao, Xuyan Shi, Jingjin Ding, Wang Liu, Huabin He, Kun Wang, Feng Shao. Nature 2017
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Human Monocytes Engage an Alternative Inflammasome Pathway.
Moritz M Gaidt, Thomas S Ebert, Dhruv Chauhan, Tobias Schmidt, Jonathan L Schmid-Burgk, Francesca Rapino, Avril A B Robertson, Matthew A Cooper, Thomas Graf, Veit Hornung. Immunity 2016
Moritz M Gaidt, Thomas S Ebert, Dhruv Chauhan, Tobias Schmidt, Jonathan L Schmid-Burgk, Francesca Rapino, Avril A B Robertson, Matthew A Cooper, Thomas Graf, Veit Hornung. Immunity 2016
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GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death.
Lorenzo Sborgi, Sebastian Rühl, Estefania Mulvihill, Joka Pipercevic, Rosalie Heilig, Henning Stahlberg, Christopher J Farady, Daniel J Müller, Petr Broz, Sebastian Hiller. EMBO J 2016
Lorenzo Sborgi, Sebastian Rühl, Estefania Mulvihill, Joka Pipercevic, Rosalie Heilig, Henning Stahlberg, Christopher J Farady, Daniel J Müller, Petr Broz, Sebastian Hiller. EMBO J 2016
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Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Pontus Orning, Dan Weng, Kristian Starheim, Dmitry Ratner, Zachary Best, Bettina Lee, Alexandria Brooks, Shiyu Xia, Hao Wu, Michelle A Kelliher,[...]. Science 2018
Pontus Orning, Dan Weng, Kristian Starheim, Dmitry Ratner, Zachary Best, Bettina Lee, Alexandria Brooks, Shiyu Xia, Hao Wu, Michelle A Kelliher,[...]. Science 2018
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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta.
Fabio Martinon, Kimberly Burns, Jürg Tschopp. Mol Cell 2002
Fabio Martinon, Kimberly Burns, Jürg Tschopp. Mol Cell 2002
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Inflammasomes: mechanism of assembly, regulation and signalling.
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
28
GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes.
Robin A Aglietti, Alberto Estevez, Aaron Gupta, Monica Gonzalez Ramirez, Peter S Liu, Nobuhiko Kayagaki, Claudio Ciferri, Vishva M Dixit, Erin C Dueber. Proc Natl Acad Sci U S A 2016
Robin A Aglietti, Alberto Estevez, Aaron Gupta, Monica Gonzalez Ramirez, Peter S Liu, Nobuhiko Kayagaki, Claudio Ciferri, Vishva M Dixit, Erin C Dueber. Proc Natl Acad Sci U S A 2016
26
The Gasdermin-D pore acts as a conduit for IL-1β secretion in mice.
Rosalie Heilig, Mathias S Dick, Lorenzo Sborgi, Etienne Meunier, Sebastian Hiller, Petr Broz. Eur J Immunol 2018
Rosalie Heilig, Mathias S Dick, Lorenzo Sborgi, Etienne Meunier, Sebastian Hiller, Petr Broz. Eur J Immunol 2018
26
Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.
Corey Rogers, Teresa Fernandes-Alnemri, Lindsey Mayes, Diana Alnemri, Gino Cingolani, Emad S Alnemri. Nat Commun 2017
Corey Rogers, Teresa Fernandes-Alnemri, Lindsey Mayes, Diana Alnemri, Gino Cingolani, Emad S Alnemri. Nat Commun 2017
26
Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection.
Joseph Sarhan, Beiyun C Liu, Hayley I Muendlein, Peng Li, Rachael Nilson, Amy Y Tang, Anthony Rongvaux, Stephen C Bunnell, Feng Shao, Douglas R Green,[...]. Proc Natl Acad Sci U S A 2018
Joseph Sarhan, Beiyun C Liu, Hayley I Muendlein, Peng Li, Rachael Nilson, Amy Y Tang, Anthony Rongvaux, Stephen C Bunnell, Feng Shao, Douglas R Green,[...]. Proc Natl Acad Sci U S A 2018
26
The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge.
Kaiwen W Chen, Christina J Groß, Flor Vásquez Sotomayor, Katryn J Stacey, Jurg Tschopp, Matthew J Sweet, Kate Schroder. Cell Rep 2014
Kaiwen W Chen, Christina J Groß, Flor Vásquez Sotomayor, Katryn J Stacey, Jurg Tschopp, Matthew J Sweet, Kate Schroder. Cell Rep 2014
25
Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock.
Jon A Hagar, Daniel A Powell, Youssef Aachoui, Robert K Ernst, Edward A Miao. Science 2013
Jon A Hagar, Daniel A Powell, Youssef Aachoui, Robert K Ernst, Edward A Miao. Science 2013
25
By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation.
Ivan Zanoni, Yunhao Tan, Marco Di Gioia, James R Springstead, Jonathan C Kagan. Immunity 2017
Ivan Zanoni, Yunhao Tan, Marco Di Gioia, James R Springstead, Jonathan C Kagan. Immunity 2017
26
Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan.
Andrea J Wolf, Christopher N Reyes, Wenbin Liang, Courtney Becker, Kenichi Shimada, Matthew L Wheeler, Hee Cheol Cho, Narcis I Popescu, K Mark Coggeshall, Moshe Arditi,[...]. Cell 2016
Andrea J Wolf, Christopher N Reyes, Wenbin Liang, Courtney Becker, Kenichi Shimada, Matthew L Wheeler, Hee Cheol Cho, Narcis I Popescu, K Mark Coggeshall, Moshe Arditi,[...]. Cell 2016
23
Cryo-EM structure of the gasdermin A3 membrane pore.
Jianbin Ruan, Shiyu Xia, Xing Liu, Judy Lieberman, Hao Wu. Nature 2018
Jianbin Ruan, Shiyu Xia, Xing Liu, Judy Lieberman, Hao Wu. Nature 2018
23
The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages.
Lan H Chu, Mohanalaxmi Indramohan, Rojo A Ratsimandresy, Anu Gangopadhyay, Emily P Morris, Denise M Monack, Andrea Dorfleutner, Christian Stehlik. Nat Commun 2018
Lan H Chu, Mohanalaxmi Indramohan, Rojo A Ratsimandresy, Anu Gangopadhyay, Emily P Morris, Denise M Monack, Andrea Dorfleutner, Christian Stehlik. Nat Commun 2018
28
Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular traps.
Kaiwen W Chen, Mercedes Monteleone, Dave Boucher, Gabriel Sollberger, Divya Ramnath, Nicholas D Condon, Jessica B von Pein, Petr Broz, Matthew J Sweet, Kate Schroder. Sci Immunol 2018
Kaiwen W Chen, Mercedes Monteleone, Dave Boucher, Gabriel Sollberger, Divya Ramnath, Nicholas D Condon, Jessica B von Pein, Petr Broz, Matthew J Sweet, Kate Schroder. Sci Immunol 2018
20
Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation.
Corey Rogers, Dan A Erkes, Alexandria Nardone, Andrew E Aplin, Teresa Fernandes-Alnemri, Emad S Alnemri. Nat Commun 2019
Corey Rogers, Dan A Erkes, Alexandria Nardone, Andrew E Aplin, Teresa Fernandes-Alnemri, Emad S Alnemri. Nat Commun 2019
20
Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly.
Kaiwen W Chen, Benjamin Demarco, Rosalie Heilig, Kateryna Shkarina, Andreas Boettcher, Christopher J Farady, Pawel Pelczar, Petr Broz. EMBO J 2019
Kaiwen W Chen, Benjamin Demarco, Rosalie Heilig, Kateryna Shkarina, Andreas Boettcher, Christopher J Farady, Pawel Pelczar, Petr Broz. EMBO J 2019
20
Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages.
Cornelius Y Taabazuing, Marian C Okondo, Daniel A Bachovchin. Cell Chem Biol 2017
Cornelius Y Taabazuing, Marian C Okondo, Daniel A Bachovchin. Cell Chem Biol 2017
19
Gasdermin D plays a vital role in the generation of neutrophil extracellular traps.
Gabriel Sollberger, Axel Choidas, Garth Lawrence Burn, Peter Habenberger, Raffaella Di Lucrezia, Susanne Kordes, Sascha Menninger, Jan Eickhoff, Peter Nussbaumer, Bert Klebl,[...]. Sci Immunol 2018
Gabriel Sollberger, Axel Choidas, Garth Lawrence Burn, Peter Habenberger, Raffaella Di Lucrezia, Susanne Kordes, Sascha Menninger, Jan Eickhoff, Peter Nussbaumer, Bert Klebl,[...]. Sci Immunol 2018
18
Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux.
Sebastian Rühl, Petr Broz. Eur J Immunol 2015
Sebastian Rühl, Petr Broz. Eur J Immunol 2015
18
Gasdermin E suppresses tumour growth by activating anti-tumour immunity.
Zhibin Zhang, Ying Zhang, Shiyu Xia, Qing Kong, Shunying Li, Xing Liu, Caroline Junqueira, Karla F Meza-Sosa, Temy Mo Yin Mok, James Ansara,[...]. Nature 2020
Zhibin Zhang, Ying Zhang, Shiyu Xia, Qing Kong, Shunying Li, Xing Liu, Caroline Junqueira, Karla F Meza-Sosa, Temy Mo Yin Mok, James Ansara,[...]. Nature 2020
18
Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death.
Hiroto Kambara, Fei Liu, Xiaoyu Zhang, Peng Liu, Besnik Bajrami, Yan Teng, Li Zhao, Shiyi Zhou, Hongbo Yu, Weidong Zhou,[...]. Cell Rep 2018
Hiroto Kambara, Fei Liu, Xiaoyu Zhang, Peng Liu, Besnik Bajrami, Yan Teng, Li Zhao, Shiyi Zhou, Hongbo Yu, Weidong Zhou,[...]. Cell Rep 2018
17
Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis.
Congqing Wu, Wei Lu, Yan Zhang, Guoying Zhang, Xuyan Shi, Yohei Hisada, Steven P Grover, Xinyi Zhang, Lan Li, Binggang Xiang,[...]. Immunity 2019
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The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.
Meihong Deng, Yiting Tang, Wenbo Li, Xiangyu Wang, Rui Zhang, Xianying Zhang, Xin Zhao, Jian Liu, Cheng Tang, Zhonghua Liu,[...]. Immunity 2018
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17
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages.
Susan L Fink, Brad T Cookson. Cell Microbiol 2006
Susan L Fink, Brad T Cookson. Cell Microbiol 2006
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Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells.
Zhiwei Zhou, Huabin He, Kun Wang, Xuyan Shi, Yupeng Wang, Ya Su, Yao Wang, Da Li, Wang Liu, Yongliang Zhang,[...]. Science 2020
Zhiwei Zhou, Huabin He, Kun Wang, Xuyan Shi, Yupeng Wang, Ya Su, Yao Wang, Da Li, Wang Liu, Yongliang Zhang,[...]. Science 2020
16
The gasdermins, a protein family executing cell death and inflammation.
Petr Broz, Pablo Pelegrín, Feng Shao. Nat Rev Immunol 2020
Petr Broz, Pablo Pelegrín, Feng Shao. Nat Rev Immunol 2020
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Gout-associated uric acid crystals activate the NALP3 inflammasome.
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
15
Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis.
Joseph K Rathkey, Junjie Zhao, Zhonghua Liu, Yinghua Chen, Jie Yang, Hannah C Kondolf, Bryan L Benson, Steven M Chirieleison, Alex Y Huang, George R Dubyak,[...]. Sci Immunol 2018
Joseph K Rathkey, Junjie Zhao, Zhonghua Liu, Yinghua Chen, Jie Yang, Hannah C Kondolf, Bryan L Benson, Steven M Chirieleison, Alex Y Huang, George R Dubyak,[...]. Sci Immunol 2018
15
Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner.
Masaru Tamura, Shigekazu Tanaka, Tomoaki Fujii, Aya Aoki, Hiromitu Komiyama, Kiyoshi Ezawa, Kenta Sumiyama, Tomoko Sagai, Toshihiko Shiroishi. Genomics 2007
Masaru Tamura, Shigekazu Tanaka, Tomoaki Fujii, Aya Aoki, Hiromitu Komiyama, Kiyoshi Ezawa, Kenta Sumiyama, Tomoko Sagai, Toshihiko Shiroishi. Genomics 2007
15
K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
Raúl Muñoz-Planillo, Peter Kuffa, Giovanny Martínez-Colón, Brenna L Smith, Thekkelnaycke M Rajendiran, Gabriel Núñez. Immunity 2013
Raúl Muñoz-Planillo, Peter Kuffa, Giovanny Martínez-Colón, Brenna L Smith, Thekkelnaycke M Rajendiran, Gabriel Núñez. Immunity 2013
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The NLRP3 inflammasome: molecular activation and regulation to therapeutics.
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
15
N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis.
Mausita Karmakar, Martin Minns, Elyse N Greenberg, Jose Diaz-Aponte, Kersi Pestonjamasp, Jennifer L Johnson, Joseph K Rathkey, Derek W Abbott, Kun Wang, Feng Shao,[...]. Nat Commun 2020
Mausita Karmakar, Martin Minns, Elyse N Greenberg, Jose Diaz-Aponte, Kersi Pestonjamasp, Jennifer L Johnson, Joseph K Rathkey, Derek W Abbott, Kun Wang, Feng Shao,[...]. Nat Commun 2020
17
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.
Jun Jacob Hu, Xing Liu, Shiyu Xia, Zhibin Zhang, Ying Zhang, Jingxia Zhao, Jianbin Ruan, Xuemei Luo, Xiwen Lou, Yang Bai,[...]. Nat Immunol 2020
Jun Jacob Hu, Xing Liu, Shiyu Xia, Zhibin Zhang, Ying Zhang, Jingxia Zhao, Jianbin Ruan, Xuemei Luo, Xiwen Lou, Yang Bai,[...]. Nat Immunol 2020
15
Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion.
Mercedes Monteleone, Amanda C Stanley, Kaiwen W Chen, Darren L Brown, Jelena S Bezbradica, Jessica B von Pein, Caroline L Holley, Dave Boucher, Melanie R Shakespear, Ronan Kapetanovic,[...]. Cell Rep 2018
Mercedes Monteleone, Amanda C Stanley, Kaiwen W Chen, Darren L Brown, Jelena S Bezbradica, Jessica B von Pein, Caroline L Holley, Dave Boucher, Melanie R Shakespear, Ronan Kapetanovic,[...]. Cell Rep 2018
14
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.