A citation-based method for searching scientific literature

Neil Justin, Ying Zhang, Cataldo Tarricone, Stephen R Martin, Shuyang Chen, Elizabeth Underwood, Valeria De Marco, Lesley F Haire, Philip A Walker, Danny Reinberg, Jon R Wilson, Steven J Gamblin. Nat Commun 2016
Times Cited: 205







List of co-cited articles
1270 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma.
Peter W Lewis, Manuel M Müller, Matthew S Koletsky, Francisco Cordero, Shu Lin, Laura A Banaszynski, Benjamin A Garcia, Tom W Muir, Oren J Becher, C David Allis. Science 2013
731
49

Role of the polycomb protein EED in the propagation of repressive histone marks.
Raphael Margueron, Neil Justin, Katsuhito Ohno, Miriam L Sharpe, Jinsook Son, William J Drury, Philipp Voigt, Stephen R Martin, William R Taylor, Valeria De Marco,[...]. Nature 2009
735
46


Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.
Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu, David T W Jones, Elke Pfaff, Karine Jacob, Dominik Sturm, Adam M Fontebasso, Dong-Anh Khuong Quang, Martje Tönjes,[...]. Nature 2012
40

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression.
Kui-Ming Chan, Dong Fang, Haiyun Gan, Rintaro Hashizume, Chuanhe Yu, Mark Schroeder, Nalin Gupta, Sabine Mueller, C David James, Robert Jenkins,[...]. Genes Dev 2013
412
38

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas.
Gang Wu, Alberto Broniscer, Troy A McEachron, Charles Lu, Barbara S Paugh, Jared Becksfort, Chunxu Qu, Li Ding, Robert Huether, Matthew Parker,[...]. Nat Genet 2012
952
38

Structures of human PRC2 with its cofactors AEBP2 and JARID2.
Vignesh Kasinath, Marco Faini, Simon Poepsel, Dvir Reif, Xinyu Ashlee Feng, Goran Stjepanovic, Ruedi Aebersold, Eva Nogales. Science 2018
92
39

The Polycomb complex PRC2 and its mark in life.
Raphaël Margueron, Danny Reinberg. Nature 2011
36

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas.
Sebastian Bender, Yujie Tang, Anders M Lindroth, Volker Hovestadt, David T W Jones, Marcel Kool, Marc Zapatka, Paul A Northcott, Dominik Sturm, Wei Wang,[...]. Cancer Cell 2013
410
34

Histone methylation by PRC2 is inhibited by active chromatin marks.
Frank W Schmitges, Archana B Prusty, Mahamadou Faty, Alexandra Stützer, Gondichatnahalli M Lingaraju, Jonathan Aiwazian, Ragna Sack, Daniel Hess, Ling Li, Shaolian Zhou,[...]. Mol Cell 2011
428
33

Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma.
James M Stafford, Chul-Hwan Lee, Philipp Voigt, Nicolas Descostes, Ricardo Saldaña-Meyer, Jia-Ray Yu, Gary Leroy, Ozgur Oksuz, Jessica R Chapman, Fernando Suarez,[...]. Sci Adv 2018
65
47

Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas.
Andrea Piunti, Rintaro Hashizume, Marc A Morgan, Elizabeth T Bartom, Craig M Horbinski, Stacy A Marshall, Emily J Rendleman, Quanhong Ma, Yoh-Hei Takahashi, Ashley R Woodfin,[...]. Nat Med 2017
195
30

Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.
Serena Sanulli, Neil Justin, Aurélie Teissandier, Katia Ancelin, Manuela Portoso, Matthieu Caron, Audrey Michaud, Berangère Lombard, Simao T da Rocha, John Offer,[...]. Mol Cell 2015
146
29

Role of histone H3 lysine 27 methylation in Polycomb-group silencing.
Ru Cao, Liangjun Wang, Hengbin Wang, Li Xia, Hediye Erdjument-Bromage, Paul Tempst, Richard S Jones, Yi Zhang. Science 2002
29

EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas.
Faizaan Mohammad, Simon Weissmann, Benjamin Leblanc, Deo P Pandey, Jonas W Højfeldt, Itys Comet, Chunqin Zheng, Jens Vilstrup Johansen, Nicolas Rapin, Bo T Porse,[...]. Nat Med 2017
240
28

Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA.
Xueyin Wang, Richard D Paucek, Anne R Gooding, Zachary Z Brown, Eva J Ge, Tom W Muir, Thomas R Cech. Nat Struct Mol Biol 2017
115
27

Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression.
Jon D Larson, Lawryn H Kasper, Barbara S Paugh, Hongjian Jin, Gang Wu, Chang-Hyuk Kwon, Yiping Fan, Timothy I Shaw, André B Silveira, Chunxu Qu,[...]. Cancer Cell 2019
95
27

Capturing the Onset of PRC2-Mediated Repressive Domain Formation.
Ozgur Oksuz, Varun Narendra, Chul-Hwan Lee, Nicolas Descostes, Gary LeRoy, Ramya Raviram, Lili Blumenberg, Kelly Karch, Pedro P Rocha, Benjamin A Garcia,[...]. Mol Cell 2018
94
26

Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes.
Simon Poepsel, Vignesh Kasinath, Eva Nogales. Nat Struct Mol Biol 2018
99
25

Genome Regulation by Polycomb and Trithorax: 70 Years and Counting.
Bernd Schuettengruber, Henri-Marc Bourbon, Luciano Di Croce, Giacomo Cavalli. Cell 2017
374
24

H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis.
Ashot S Harutyunyan, Brian Krug, Haifen Chen, Simon Papillon-Cavanagh, Michele Zeinieh, Nicolas De Jay, Shriya Deshmukh, Carol C L Chen, Jad Belle, Leonie G Mikael,[...]. Nat Commun 2019
85
28

Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin.
Chul-Hwan Lee, Jia-Ray Yu, Sunil Kumar, Ying Jin, Gary LeRoy, Natarajan Bhanu, Syuzo Kaneko, Benjamin A Garcia, Andrew D Hamilton, Danny Reinberg. Mol Cell 2018
54
42

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.
Dominik Sturm, Hendrik Witt, Volker Hovestadt, Dong-Anh Khuong-Quang, David T W Jones, Carolin Konermann, Elke Pfaff, Martje Tönjes, Martin Sill, Sebastian Bender,[...]. Cancer Cell 2012
23

H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas.
Manav Pathania, Nicolas De Jay, Nicola Maestro, Ashot S Harutyunyan, Justyna Nitarska, Pirasteh Pahlavan, Stephen Henderson, Leonie G Mikael, Angela Richard-Londt, Ying Zhang,[...]. Cancer Cell 2017
98
23

Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance.
Alexei Brooun, Ketan S Gajiwala, Ya-Li Deng, Wei Liu, Ben Bolaños, Patrick Bingham, You-Ai He, Wade Diehl, Nicole Grable, Pei-Pei Kung,[...]. Nat Commun 2016
96
22

Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.
Chao Lu, Siddhant U Jain, Dominik Hoelper, Denise Bechet, Rosalynn C Molden, Leili Ran, Devan Murphy, Sriram Venneti, Meera Hameed, Bruce R Pawel,[...]. Science 2016
198
22

Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation.
Kosuke Funato, Tamara Major, Peter W Lewis, C David Allis, Viviane Tabar. Science 2014
219
22


Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2.
Chul-Hwan Lee, Marlene Holder, Daniel Grau, Ricardo Saldaña-Meyer, Jia-Ray Yu, Rais Ahmad Ganai, Jenny Zhang, Miao Wang, Gary LeRoy, Marc-Werner Dobenecker,[...]. Mol Cell 2018
50
40

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein.
Andrei Kuzmichev, Kenichi Nishioka, Hediye Erdjument-Bromage, Paul Tempst, Danny Reinberg. Genes Dev 2002
20

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas.
Dong-Anh Khuong-Quang, Pawel Buczkowicz, Patricia Rakopoulos, Xiao-Yang Liu, Adam M Fontebasso, Eric Bouffet, Ute Bartels, Steffen Albrecht, Jeremy Schwartzentruber, Louis Letourneau,[...]. Acta Neuropathol 2012
541
20

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.
Alan Mackay, Anna Burford, Diana Carvalho, Elisa Izquierdo, Janat Fazal-Salom, Kathryn R Taylor, Lynn Bjerke, Matthew Clarke, Mara Vinci, Meera Nandhabalan,[...]. Cancer Cell 2017
353
20

Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.
Siming Chen, Lianying Jiao, Murtada Shubbar, Xin Yang, Xin Liu. Mol Cell 2018
54
35

H3K36 methylation antagonizes PRC2-mediated H3K27 methylation.
Wen Yuan, Mo Xu, Chang Huang, Nan Liu, She Chen, Bing Zhu. J Biol Chem 2011
309
19

Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.
Raphael Margueron, Guohong Li, Kavitha Sarma, Alexandre Blais, Jiri Zavadil, Christopher L Woodcock, Brian D Dynlacht, Danny Reinberg. Mol Cell 2008
532
19

A model for transmission of the H3K27me3 epigenetic mark.
Klaus H Hansen, Adrian P Bracken, Diego Pasini, Nikolaj Dietrich, Simmi S Gehani, Astrid Monrad, Juri Rappsilber, Mads Lerdrup, Kristian Helin. Nat Cell Biol 2008
498
18

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.
Gang Wu, Alexander K Diaz, Barbara S Paugh, Sherri L Rankin, Bensheng Ju, Yongjin Li, Xiaoyan Zhu, Chunxu Qu, Xiang Chen, Junyuan Zhang,[...]. Nat Genet 2014
579
18

The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex.
Yupeng He, Sujatha Selvaraju, Michael L Curtin, Clarissa G Jakob, Haizhong Zhu, Kenneth M Comess, Bailin Shaw, Juliana The, Evelyne Lima-Fernandes, Magdalena M Szewczyk,[...]. Nat Chem Biol 2017
111
17

An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED.
Wei Qi, Kehao Zhao, Justin Gu, Ying Huang, Youzhen Wang, Hailong Zhang, Man Zhang, Jeff Zhang, Zhengtian Yu, Ling Li,[...]. Nat Chem Biol 2017
148
17

Promiscuous RNA binding by Polycomb repressive complex 2.
Chen Davidovich, Leon Zheng, Karen J Goodrich, Thomas R Cech. Nat Struct Mol Biol 2013
305
17

A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.
Eric Conway, Emilia Jerman, Evan Healy, Shinsuke Ito, Daniel Holoch, Giorgio Oliviero, Orla Deevy, Eleanor Glancy, Darren J Fitzpatrick, Marlena Mucha,[...]. Mol Cell 2018
62
27

Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.
Sam Behjati, Patrick S Tarpey, Nadège Presneau, Susanne Scheipl, Nischalan Pillay, Peter Van Loo, David C Wedge, Susanna L Cooke, Gunes Gundem, Helen Davies,[...]. Nat Genet 2013
398
17

Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling.
Hans-Martin Herz, Marc Morgan, Xin Gao, Jessica Jackson, Ryan Rickels, Selene K Swanson, Laurence Florens, Michael P Washburn, Joel C Eissenberg, Ali Shilatifard. Science 2014
119
17

Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
Adam M Fontebasso, Simon Papillon-Cavanagh, Jeremy Schwartzentruber, Hamid Nikbakht, Noha Gerges, Pierre-Olivier Fiset, Denise Bechet, Damien Faury, Nicolas De Jay, Lori A Ramkissoon,[...]. Nat Genet 2014
253
17

Polycomb-like proteins link the PRC2 complex to CpG islands.
Haojie Li, Robert Liefke, Junyi Jiang, Jesse Vigoda Kurland, Wei Tian, Pujuan Deng, Weidi Zhang, Qian He, Dinshaw J Patel, Martha L Bulyk,[...]. Nature 2017
132
17

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes.
David Castel, Cathy Philippe, Raphaël Calmon, Ludivine Le Dret, Nathalène Truffaux, Nathalie Boddaert, Mélanie Pagès, Kathryn R Taylor, Patrick Saulnier, Ludovic Lacroix,[...]. Acta Neuropathol 2015
276
17

Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation.
Anne Laugesen, Jonas Westergaard Højfeldt, Kristian Helin. Mol Cell 2019
165
17

Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma.
Chul-Hwan Lee, Jia-Ray Yu, Jeffrey Granat, Ricardo Saldaña-Meyer, Joshua Andrade, Gary LeRoy, Ying Jin, Peder Lund, James M Stafford, Benjamin A Garcia,[...]. Genes Dev 2019
33
51

Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin.
Jinsook Son, Steven S Shen, Raphael Margueron, Danny Reinberg. Genes Dev 2013
102
16

Histone methyltransferase activity of a Drosophila Polycomb group repressor complex.
Jürg Müller, Craig M Hart, Nicole J Francis, Marcus L Vargas, Aditya Sengupta, Brigitte Wild, Ellen L Miller, Michael B O'Connor, Robert E Kingston, Jeffrey A Simon. Cell 2002
16


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.