A citation-based method for searching scientific literature

P Bernasconi-Elias, T Hu, D Jenkins, B Firestone, S Gans, E Kurth, P Capodieci, J Deplazes-Lauber, K Petropoulos, P Thiel, D Ponsel, S Hee Choi, P LeMotte, A London, M Goetcshkes, E Nolin, M D Jones, K Slocum, M J Kluk, D M Weinstock, A Christodoulou, O Weinberg, J Jaehrling, S A Ettenberg, A Buckler, S C Blacklow, J C Aster, C J Fryer. Oncogene 2016
Times Cited: 53







List of co-cited articles
1021 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
67

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
494
33

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice.
D Bellavia, A F Campese, E Alesse, A Vacca, M P Felli, A Balestri, A Stoppacciaro, C Tiveron, L Tatangelo, M Giovarelli,[...]. EMBO J 2000
299
30

Therapeutic antibody targeting of individual Notch receptors.
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
516
28

Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory Region.
Xiang Xu, Sung Hee Choi, Tiancen Hu, Kittichoat Tiyanont, Roger Habets, Arjan J Groot, Marc Vooijs, Jon C Aster, Rajiv Chopra, Christy Fryer,[...]. Structure 2015
34
44

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.
L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
28


NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers.
Hongfang Wang, Chongzhi Zang, Len Taing, Kelly L Arnett, Yinling Joey Wong, Warren S Pear, Stephen C Blacklow, X Shirley Liu, Jon C Aster. Proc Natl Acad Sci U S A 2014
150
22

Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.
Alessandra Vacca, Maria Pia Felli, Rocco Palermo, Giuseppina Di Mario, Angelica Calce, Monica Di Giovine, Luigi Frati, Alberto Gulino, Isabella Screpanti. EMBO J 2006
113
22

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
660
22

Structural basis for autoinhibition of Notch.
Wendy R Gordon, Didem Vardar-Ulu, Gavin Histen, Cheryll Sanchez-Irizarry, Jon C Aster, Stephen C Blacklow. Nat Struct Mol Biol 2007
236
22

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.
Teresa Palomero, Wei Keat Lim, Duncan T Odom, Maria Luisa Sulis, Pedro J Real, Adam Margolin, Kelly C Barnes, Jennifer O'Neil, Donna Neuberg, Andrew P Weng,[...]. Proc Natl Acad Sci U S A 2006
592
22

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.
Andrew P Weng, John M Millholland, Yumi Yashiro-Ohtani, Marie Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G Rodriguez, Hong Sai, John Tobias,[...]. Genes Dev 2006
627
22

Notch signalling in context.
Sarah J Bray. Nat Rev Mol Cell Biol 2016
479
22

Modulation of Notch signaling by antibodies specific for the extracellular negative regulatory region of NOTCH3.
Kang Li, Yucheng Li, Wenjuan Wu, Wendy R Gordon, David W Chang, Mason Lu, Shane Scoggin, Tihui Fu, Long Vien, Gavin Histen,[...]. J Biol Chem 2008
148
20

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.
Diana Bellavia, Antonio F Campese, Saula Checquolo, Anna Balestri, Andrea Biondi, Giovanni Cazzaniga, Urban Lendahl, Hans J Fehling, Adrian C Hayday, Luigi Frati,[...]. Proc Natl Acad Sci U S A 2002
161
20

Therapeutic modulation of Notch signalling--are we there yet?
Emma R Andersson, Urban Lendahl. Nat Rev Drug Discov 2014
314
20

Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency.
Wan-Ching Yen, Marcus M Fischer, Fumiko Axelrod, Christopher Bond, Jennifer Cain, Belinda Cancilla, William R Henner, Rene Meisner, Aaron Sato, Jalpa Shah,[...]. Clin Cancer Res 2015
162
20

The Varied Roles of Notch in Cancer.
Jon C Aster, Warren S Pear, Stephen C Blacklow. Annu Rev Pathol 2017
280
20

The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia.
Sung Hee Choi, Eric Severson, Warren S Pear, Xiaole S Liu, Jon C Aster, Stephen C Blacklow. PLoS One 2017
19
57

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia.
Benjamin J Thompson, Silvia Buonamici, Maria Luisa Sulis, Teresa Palomero, Tomas Vilimas, Giuseppe Basso, Adolfo Ferrando, Iannis Aifantis. J Exp Med 2007
348
18

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia.
Xose S Puente, Magda Pinyol, Víctor Quesada, Laura Conde, Gonzalo R Ordóñez, Neus Villamor, Georgia Escaramis, Pedro Jares, Sílvia Beà, Marcos González-Díaz,[...]. Nature 2011
18

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.
W S Pear, J C Aster, M L Scott, R P Hasserjian, B Soffer, J Sklar, D Baltimore. J Exp Med 1996
563
18

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.
Miguel Aste-Amézaga, Ningyan Zhang, Janet E Lineberger, Beth A Arnold, Timothy J Toner, Mingcheng Gu, Lingyi Huang, Salvatore Vitelli, Kim T Vo, Peter Haytko,[...]. PLoS One 2010
130
18

Direct inhibition of the NOTCH transcription factor complex.
Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
559
18

Notch signaling: cell fate control and signal integration in development.
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
18

Constitutive NOTCH3 Signaling Promotes the Growth of Basal Breast Cancers.
Lisa Choy, Thijs J Hagenbeek, Margaret Solon, Dorothy French, David Finkle, Amy Shelton, Rayna Venook, Matthew J Brauer, Christian W Siebel. Cancer Res 2017
52
19

Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.
V Agnusdei, S Minuzzo, C Frasson, A Grassi, F Axelrod, S Satyal, A Gurney, T Hoey, E Seganfreddo, G Basso,[...]. Leukemia 2014
82
18

Notch3 and canonical NF-kappaB signaling pathways cooperatively regulate Foxp3 transcription.
Alessandro Barbarulo, Paola Grazioli, Antonio F Campese, Diana Bellavia, Giuseppina Di Mario, Maria Pelullo, Ambra Ciuffetta, Sara Colantoni, Alessandra Vacca, Luigi Frati,[...]. J Immunol 2011
56
16

Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.
Tomas Vilimas, Joaquina Mascarenhas, Teresa Palomero, Malay Mandal, Silvia Buonamici, Fanyong Meng, Benjamín Thompson, Christina Spaulding, Sami Macaroun, Maria-Luisa Alegre,[...]. Nat Med 2007
249
16

Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer.
Giovanni Roti, Anne Carlton, Kenneth N Ross, Michele Markstein, Kostandin Pajcini, Angela H Su, Norbert Perrimon, Warren S Pear, Andrew L Kung, Stephen C Blacklow,[...]. Cancer Cell 2013
95
16

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia.
Daniel Herranz, Alberto Ambesi-Impiombato, Teresa Palomero, Stephanie A Schnell, Laura Belver, Agnieszka A Wendorff, Luyao Xu, Mireia Castillo-Martin, David Llobet-Navás, Carlos Cordon-Cardo,[...]. Nat Med 2014
252
15

PEST domain mutations in Notch receptors comprise an oncogenic driver segment in triple-negative breast cancer sensitive to a γ-secretase inhibitor.
Kai Wang, Qin Zhang, Danan Li, Keith Ching, Cathy Zhang, Xianxian Zheng, Mark Ozeck, Stephanie Shi, Xiaorong Li, Hui Wang,[...]. Clin Cancer Res 2015
91
15

Notch3 is required for arterial identity and maturation of vascular smooth muscle cells.
Valérie Domenga, Peggy Fardoux, Pierre Lacombe, Marie Monet, Jacqueline Maciazek, Luke T Krebs, Bernard Klonjkowski, Eliane Berrou, Matthias Mericskay, Zhen Li,[...]. Genes Dev 2004
358
15

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.
Pedro J Real, Valeria Tosello, Teresa Palomero, Mireia Castillo, Eva Hernando, Elisa de Stanchina, Maria Luisa Sulis, Kelly Barnes, Catherine Sawai, Irene Homminga,[...]. Nat Med 2009
323
15

Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis.
John Ridgway, Gu Zhang, Yan Wu, Scott Stawicki, Wei-Ching Liang, Yvan Chanthery, Joe Kowalski, Ryan J Watts, Christopher Callahan, Ian Kasman,[...]. Nature 2006
735
15

Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia.
V Kumar, R Palermo, C Talora, A F Campese, S Checquolo, D Bellavia, L Tottone, G Testa, E Miele, S Indraccolo,[...]. Leukemia 2014
125
15

A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.
C Papayannidis, D J DeAngelo, W Stock, B Huang, M N Shaik, R Cesari, X Zheng, J M Reynolds, P A English, M Ozeck,[...]. Blood Cancer J 2015
71
15

Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes.
Michael J Malecki, Cheryll Sanchez-Irizarry, Jennifer L Mitchell, Gavin Histen, Mina L Xu, Jon C Aster, Stephen C Blacklow. Mol Cell Biol 2006
186
15

Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL.
Wendy R Gordon, Monideepa Roy, Didem Vardar-Ulu, Megan Garfinkel, Marc R Mansour, Jon C Aster, Stephen C Blacklow. Blood 2009
117
15

The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.
Lluis Espinosa, Severine Cathelin, Teresa D'Altri, Thomas Trimarchi, Alexander Statnikov, Jordi Guiu, Veronica Rodilla, Julia Inglés-Esteve, Josep Nomdedeu, Beatriz Bellosillo,[...]. Cancer Cell 2010
201
13

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE.
C Brou, F Logeat, N Gupta, C Bessia, O LeBail, J R Doedens, A Cumano, P Roux, R A Black, A Israël. Mol Cell 2000
840
13

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.
Nicholas J Wang, Zachary Sanborn, Kelly L Arnett, Laura J Bayston, Wilson Liao, Charlotte M Proby, Irene M Leigh, Eric A Collisson, Patricia B Gordon, Lakshmi Jakkula,[...]. Proc Natl Acad Sci U S A 2011
312
13

Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia.
Thomas Trimarchi, Erhan Bilal, Panagiotis Ntziachristos, Giulia Fabbri, Riccardo Dalla-Favera, Aristotelis Tsirigos, Iannis Aifantis. Cell 2014
313
13

Deficient T cell fate specification in mice with an induced inactivation of Notch1.
F Radtke, A Wilson, G Stark, M Bauer, J van Meerwijk, H R MacDonald, M Aguet. Immunity 1999
13

A new tumor suppressor role for the Notch pathway in bladder cancer.
Theodoros Rampias, Paraskevi Vgenopoulou, Margaritis Avgeris, Alexander Polyzos, Konstantinos Stravodimos, Christos Valavanis, Andreas Scorilas, Apostolos Klinakis. Nat Med 2014
121
13

Non-canonical notch signaling in cancer and immunity.
Furkan Ayaz, Barbara A Osborne. Front Oncol 2014
94
13

The molecular basis of notch signaling regulation: a complex simplicity.
R Palermo, S Checquolo, D Bellavia, C Talora, I Screpanti. Curr Mol Med 2014
27
25

Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression.
G Franciosa, G Diluvio, F Del Gaudio, M V Giuli, R Palermo, P Grazioli, A F Campese, C Talora, D Bellavia, G D'Amati,[...]. Oncogene 2016
38
18

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation.
Joseph Milano, Jenny McKay, Claude Dagenais, Linda Foster-Brown, Francois Pognan, Reto Gadient, Robert T Jacobs, Anna Zacco, Barry Greenberg, Paul J Ciaccio. Toxicol Sci 2004
412
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.