Sarah J Stein, Ethan A Mack, Kelly S Rome, Kostandin V Pajcini, Takuya Ohtani, Lanwei Xu, Yunlei Li, Jules P P Meijerink, Robert B Faryabi, Warren S Pear. PLoS One 2016
Times Cited: 15
Times Cited: 15
Times Cited
Times Co-cited
Similarity
Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia.
Karen Keeshan, Yiping He, Bas J Wouters, Olga Shestova, Lanwei Xu, Hong Sai, Carlos G Rodriguez, Ivan Maillard, John W Tobias, Peter Valk,[...]. Cancer Cell 2006
Karen Keeshan, Yiping He, Bas J Wouters, Olga Shestova, Lanwei Xu, Hong Sai, Carlos G Rodriguez, Ivan Maillard, John W Tobias, Peter Valk,[...]. Cancer Cell 2006
86
TRIB2 regulates normal and stress-induced thymocyte proliferation.
Kai Ling Liang, Caitriona O'Connor, J Pedro Veiga, Tommie V McCarthy, Karen Keeshan. Cell Discov 2016
Kai Ling Liang, Caitriona O'Connor, J Pedro Veiga, Tommie V McCarthy, Karen Keeshan. Cell Discov 2016
66
Regulation of Trib2 by an E2F1-C/EBPα feedback loop in AML cell proliferation.
Loveena Rishi, Maura Hannon, Mara Salomè, Marie Hasemann, Anne-Katrine Frank, Joana Campos, Jennifer Timoney, Caitriona O'Connor, Mary R Cahill, Bo Porse,[...]. Blood 2014
Loveena Rishi, Maura Hannon, Mara Salomè, Marie Hasemann, Anne-Katrine Frank, Joana Campos, Jennifer Timoney, Caitriona O'Connor, Mary R Cahill, Bo Porse,[...]. Blood 2014
60
Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia.
Priya H Dedhia, Karen Keeshan, Sacha Uljon, Lanwei Xu, Maria E Vega, Olga Shestova, Meirav Zaks-Zilberman, Candice Romany, Stephen C Blacklow, Warren S Pear. Blood 2010
Priya H Dedhia, Karen Keeshan, Sacha Uljon, Lanwei Xu, Maria E Vega, Olga Shestova, Meirav Zaks-Zilberman, Candice Romany, Stephen C Blacklow, Warren S Pear. Blood 2010
46
TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver.
Keyong Du, Stephan Herzig, Rohit N Kulkarni, Marc Montminy. Science 2003
Keyong Du, Stephan Herzig, Rohit N Kulkarni, Marc Montminy. Science 2003
46
Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding.
Karen Keeshan, Will Bailis, Priya H Dedhia, Maria E Vega, Olga Shestova, Lanwei Xu, Kristin Toscano, Sacha N Uljon, Stephen C Blacklow, Warren S Pear. Blood 2010
Karen Keeshan, Will Bailis, Priya H Dedhia, Maria E Vega, Olga Shestova, Lanwei Xu, Kristin Toscano, Sacha N Uljon, Stephen C Blacklow, Warren S Pear. Blood 2010
46
TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT.
Richard Hill, Patricia A Madureira, Bibiana Ferreira, Inês Baptista, Susana Machado, Laura Colaço, Marta Dos Santos, Ningshu Liu, Ana Dopazo, Selma Ugurel,[...]. Nat Commun 2017
Richard Hill, Patricia A Madureira, Bibiana Ferreira, Inês Baptista, Susana Machado, Laura Colaço, Marta Dos Santos, Ningshu Liu, Ana Dopazo, Selma Ugurel,[...]. Nat Commun 2017
46
Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease.
Patrick A Eyers, Karen Keeshan, Natarajan Kannan. Trends Cell Biol 2017
Patrick A Eyers, Karen Keeshan, Natarajan Kannan. Trends Cell Biol 2017
46
Linkage of Meis1 leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3.
Bob Argiropoulos, Lars Palmqvist, Eric Yung, Florian Kuchenbauer, Michael Heuser, Laura M Sly, Adrian Wan, Gerald Krystal, R Keith Humphries. Exp Hematol 2008
Bob Argiropoulos, Lars Palmqvist, Eric Yung, Florian Kuchenbauer, Michael Heuser, Laura M Sly, Adrian Wan, Gerald Krystal, R Keith Humphries. Exp Hematol 2008
40
The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia.
C O'Connor, F Lohan, J Campos, E Ohlsson, M Salomè, C Forde, R Artschwager, R M Liskamp, M R Cahill, P A Kiely,[...]. Oncogene 2016
C O'Connor, F Lohan, J Campos, E Ohlsson, M Salomè, C Forde, R Artschwager, R M Liskamp, M R Cahill, P A Kiely,[...]. Oncogene 2016
40
Tribbles in disease: Signaling pathways important for cellular function and neoplastic transformation.
Takashi Yokoyama, Takuro Nakamura. Cancer Sci 2011
Takashi Yokoyama, Takuro Nakamura. Cancer Sci 2011
40
Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis.
Takashi Yokoyama, Yohei Kanno, Yukari Yamazaki, Tomoko Takahara, Satoshi Miyata, Takuro Nakamura. Blood 2010
Takashi Yokoyama, Yohei Kanno, Yukari Yamazaki, Tomoko Takahara, Satoshi Miyata, Takuro Nakamura. Blood 2010
40
Human TRIB2 Oscillates during the Cell Cycle and Promotes Ubiquitination and Degradation of CDC25C.
Kai Ling Liang, Roberto Paredes, Ruaidhri Carmody, Patrick A Eyers, Stefan Meyer, Tommie V McCarthy, Karen Keeshan. Int J Mol Sci 2016
Kai Ling Liang, Roberto Paredes, Ruaidhri Carmody, Patrick A Eyers, Stefan Meyer, Tommie V McCarthy, Karen Keeshan. Int J Mol Sci 2016
46
Tribbles homolog 2 (Trib2) and HoxA9 cooperate to accelerate acute myelogenous leukemia.
Karen Keeshan, Olga Shestova, LaShon Ussin, Warren S Pear. Blood Cells Mol Dis 2008
Karen Keeshan, Olga Shestova, LaShon Ussin, Warren S Pear. Blood Cells Mol Dis 2008
40
Molecular Mechanism of CCAAT-Enhancer Binding Protein Recruitment by the TRIB1 Pseudokinase.
James M Murphy, Yoshio Nakatani, Sam A Jamieson, Weiwen Dai, Isabelle S Lucet, Peter D Mace. Structure 2015
James M Murphy, Yoshio Nakatani, Sam A Jamieson, Weiwen Dai, Isabelle S Lucet, Peter D Mace. Structure 2015
40
TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function.
Jiayi Wang, Joo-Seop Park, Yingying Wei, Mihir Rajurkar, Jennifer L Cotton, Qishi Fan, Brian C Lewis, Hongkai Ji, Junhao Mao. Mol Cell 2013
Jiayi Wang, Joo-Seop Park, Yingying Wei, Mihir Rajurkar, Jennifer L Cotton, Qishi Fan, Brian C Lewis, Hongkai Ji, Junhao Mao. Mol Cell 2013
33
Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells.
F Zanella, O Renner, B García, S Callejas, A Dopazo, S Peregrina, A Carnero, W Link. Oncogene 2010
F Zanella, O Renner, B García, S Callejas, A Dopazo, S Peregrina, A Carnero, W Link. Oncogene 2010
33
Tribbles in inflammation.
Jessica Johnston, Shaghayegh Basatvat, Zabran Ilyas, Sheila Francis, Endre Kiss-Toth. Biochem Soc Trans 2015
Jessica Johnston, Shaghayegh Basatvat, Zabran Ilyas, Sheila Francis, Endre Kiss-Toth. Biochem Soc Trans 2015
33
Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1.
Bas J Wouters, Meritxell Alberich Jordà, Karen Keeshan, Irene Louwers, Claudia A J Erpelinck-Verschueren, Dennis Tielemans, Anton W Langerak, Yiping He, Yumi Yashiro-Ohtani, Pu Zhang,[...]. Blood 2007
Bas J Wouters, Meritxell Alberich Jordà, Karen Keeshan, Irene Louwers, Claudia A J Erpelinck-Verschueren, Dennis Tielemans, Anton W Langerak, Yiping He, Yumi Yashiro-Ohtani, Pu Zhang,[...]. Blood 2007
33
Overexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C/EBPα.
K B Grandinetti, T A Stevens, S Ha, R J Salamone, J R Walker, J Zhang, S Agarwalla, D G Tenen, E C Peters, V A Reddy. Oncogene 2011
K B Grandinetti, T A Stevens, S Ha, R J Salamone, J R Walker, J Zhang, S Agarwalla, D G Tenen, E C Peters, V A Reddy. Oncogene 2011
33
TRIB2 and the ubiquitin proteasome system in cancer.
Mara Salomè, Joana Campos, Karen Keeshan. Biochem Soc Trans 2015
Mara Salomè, Joana Campos, Karen Keeshan. Biochem Soc Trans 2015
33
Tribbles in normal and malignant haematopoiesis.
Sarah J Stein, Ethan A Mack, Kelly S Rome, Warren S Pear. Biochem Soc Trans 2015
Sarah J Stein, Ethan A Mack, Kelly S Rome, Warren S Pear. Biochem Soc Trans 2015
33
Human tribbles, a protein family controlling mitogen-activated protein kinase cascades.
Endre Kiss-Toth, Stephanie M Bagstaff, Hye Y Sung, Veronika Jozsa, Clare Dempsey, Jim C Caunt, Kevin M Oxley, David H Wyllie, Timea Polgar, Mary Harte,[...]. J Biol Chem 2004
Endre Kiss-Toth, Stephanie M Bagstaff, Hye Y Sung, Veronika Jozsa, Clare Dempsey, Jim C Caunt, Kevin M Oxley, David H Wyllie, Timea Polgar, Mary Harte,[...]. J Biol Chem 2004
33
TRIB2 inhibits Wnt/β-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, β-TrCP, COP1 and Smurf1, in liver cancer cells.
Shanshan Xu, Minghong Tong, Jingqin Huang, Yue Zhang, Yongxia Qiao, Wenhao Weng, Weiwei Liu, Jiayi Wang, Fenyong Sun. FEBS Lett 2014
Shanshan Xu, Minghong Tong, Jingqin Huang, Yue Zhang, Yongxia Qiao, Wenhao Weng, Weiwei Liu, Jiayi Wang, Fenyong Sun. FEBS Lett 2014
26
Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis.
Guang Jin, Yukari Yamazaki, Miki Takuwa, Tomoko Takahara, Keiko Kaneko, Takeshi Kuwata, Satoshi Miyata, Takuro Nakamura. Blood 2007
Guang Jin, Yukari Yamazaki, Miki Takuwa, Tomoko Takahara, Keiko Kaneko, Takeshi Kuwata, Satoshi Miyata, Takuro Nakamura. Blood 2007
26
Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia.
Takaomi Sanda, Lee N Lawton, M Inmaculada Barrasa, Zi Peng Fan, Holger Kohlhammer, Alejandro Gutierrez, Wenxue Ma, Jessica Tatarek, Yebin Ahn, Michelle A Kelliher,[...]. Cancer Cell 2012
Takaomi Sanda, Lee N Lawton, M Inmaculada Barrasa, Zi Peng Fan, Holger Kohlhammer, Alejandro Gutierrez, Wenxue Ma, Jessica Tatarek, Yebin Ahn, Michelle A Kelliher,[...]. Cancer Cell 2012
26
Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice.
D E Zhang, P Zhang, N D Wang, C J Hetherington, G J Darlington, D G Tenen. Proc Natl Acad Sci U S A 1997
D E Zhang, P Zhang, N D Wang, C J Hetherington, G J Darlington, D G Tenen. Proc Natl Acad Sci U S A 1997
26
Tribbles coordinates mitosis and morphogenesis in Drosophila by regulating string/CDC25 proteolysis.
J Mata, S Curado, A Ephrussi, P Rørth. Cell 2000
J Mata, S Curado, A Ephrussi, P Rørth. Cell 2000
26
Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in liver cancer.
Jiayi Wang, Yue Zhang, Wenhao Weng, Yongxia Qiao, Lifang Ma, Weifan Xiao, Yongchun Yu, Qiuhui Pan, Fenyong Sun. J Biol Chem 2013
Jiayi Wang, Yue Zhang, Wenhao Weng, Yongxia Qiao, Lifang Ma, Weifan Xiao, Yongchun Yu, Qiuhui Pan, Fenyong Sun. J Biol Chem 2013
26
TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence.
Ke Li, Feng Wang, Wen-Bin Cao, Xiao-Xi Lv, Fang Hua, Bing Cui, Jiao-Jiao Yu, Xiao-Wei Zhang, Shuang Shang, Shan-Shan Liu,[...]. Cancer Cell 2017
Ke Li, Feng Wang, Wen-Bin Cao, Xiao-Xi Lv, Fang Hua, Bing Cui, Jiao-Jiao Yu, Xiao-Wei Zhang, Shuang Shang, Shan-Shan Liu,[...]. Cancer Cell 2017
26
Tribbles-1 and -2 are tumour suppressors, down-regulated in human acute myeloid leukaemia.
Daniel C Gilby, Hye Youn Sung, Peter R Winship, Anne C Goodeve, John T Reilly, Endre Kiss-Toth. Immunol Lett 2010
Daniel C Gilby, Hye Youn Sung, Peter R Winship, Anne C Goodeve, John T Reilly, Endre Kiss-Toth. Immunol Lett 2010
26
Trib2 expression in granulocyte-monocyte progenitors drives a highly drug resistant acute myeloid leukaemia linked to elevated Bcl2.
Caitriona O'Connor, Krishna Yalla, Mara Salomé, Hothri Ananyambica Moka, Eduardo Gómez Castañeda, Patrick A Eyers, Karen Keeshan. Oncotarget 2018
Caitriona O'Connor, Krishna Yalla, Mara Salomé, Hothri Ananyambica Moka, Eduardo Gómez Castañeda, Patrick A Eyers, Karen Keeshan. Oncotarget 2018
40
Murine tribbles homolog 2 deficiency affects erythroid progenitor development and confers macrocytic anemia on mice.
Kou-Ray Lin, Hsin-Fang Yang-Yen, Huang-Wei Lien, Wei-Hao Liao, Chang-Jen Huang, Liang-In Lin, Chung-Leung Li, Jeffrey Jong-Young Yen. Sci Rep 2016
Kou-Ray Lin, Hsin-Fang Yang-Yen, Huang-Wei Lien, Wei-Hao Liao, Chang-Jen Huang, Liang-In Lin, Chung-Leung Li, Jeffrey Jong-Young Yen. Sci Rep 2016
66
Elevated TRIB2 with NOTCH1 activation in paediatric/adult T-ALL.
Maura M Hannon, Fiona Lohan, Yucel Erbilgin, Muge Sayitoglu, Kathleen O'Hagan, Ken Mills, Ugur Ozbek, Karen Keeshan. Br J Haematol 2012
Maura M Hannon, Fiona Lohan, Yucel Erbilgin, Muge Sayitoglu, Kathleen O'Hagan, Ken Mills, Ugur Ozbek, Karen Keeshan. Br J Haematol 2012
26
Tribbles-2 is a novel regulator of inflammatory activation of monocytes.
Katalin Eder, Hongtao Guan, Hye Y Sung, Jon Ward, Adrienn Angyal, Michelle Janas, Gabriella Sarmay, Erno Duda, Martin Turner, Steven K Dower,[...]. Int Immunol 2008
Katalin Eder, Hongtao Guan, Hye Y Sung, Jon Ward, Adrienn Angyal, Michelle Janas, Gabriella Sarmay, Erno Duda, Martin Turner, Steven K Dower,[...]. Int Immunol 2008
26
Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages.
Takashi Satoh, Hiroyasu Kidoya, Hisamichi Naito, Masahiro Yamamoto, Naoki Takemura, Katsuhiro Nakagawa, Yoshichika Yoshioka, Eiichi Morii, Nobuyuki Takakura, Osamu Takeuchi,[...]. Nature 2013
Takashi Satoh, Hiroyasu Kidoya, Hisamichi Naito, Masahiro Yamamoto, Naoki Takemura, Katsuhiro Nakagawa, Yoshichika Yoshioka, Eiichi Morii, Nobuyuki Takakura, Osamu Takeuchi,[...]. Nature 2013
26
A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling.
Mara Salomé, Aoife Magee, Krisha Yalla, Shahzya Chaudhury, Evgenia Sarrou, Ruaidhrí J Carmody, Karen Keeshan. Cell Death Dis 2018
Mara Salomé, Aoife Magee, Krisha Yalla, Shahzya Chaudhury, Evgenia Sarrou, Ruaidhrí J Carmody, Karen Keeshan. Cell Death Dis 2018
26
Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha.
Pu Zhang, Junko Iwasaki-Arai, Hiromi Iwasaki, Maris L Fenyus, Tajhal Dayaram, Bronwyn M Owens, Hirokazu Shigematsu, Elena Levantini, Claudia S Huettner, Julie A Lekstrom-Himes,[...]. Immunity 2004
Pu Zhang, Junko Iwasaki-Arai, Hiromi Iwasaki, Maris L Fenyus, Tajhal Dayaram, Bronwyn M Owens, Hirokazu Shigematsu, Elena Levantini, Claudia S Huettner, Julie A Lekstrom-Himes,[...]. Immunity 2004
26
TRB2, a mouse Tribbles ortholog, suppresses adipocyte differentiation by inhibiting AKT and C/EBPbeta.
Takahiro Naiki, Eiko Saijou, Yuichiro Miyaoka, Keisuke Sekine, Atsushi Miyajima. J Biol Chem 2007
Takahiro Naiki, Eiko Saijou, Yuichiro Miyaoka, Keisuke Sekine, Atsushi Miyajima. J Biol Chem 2007
26
20
Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPα as a common target of TRIB1 and PML/RARA.
Karen Keeshan, Pauline Vieugué, Shahzya Chaudhury, Loveena Rishi, Coline Gaillard, Lu Liang, Elaine Garcia, Takuro Nakamura, Nader Omidvar, Scott C Kogan. Haematologica 2016
Karen Keeshan, Pauline Vieugué, Shahzya Chaudhury, Loveena Rishi, Coline Gaillard, Lu Liang, Elaine Garcia, Takuro Nakamura, Nader Omidvar, Scott C Kogan. Haematologica 2016
20
The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner.
Fiona P Bailey, Dominic P Byrne, Krishnadev Oruganty, Claire E Eyers, Christopher J Novotny, Kevan M Shokat, Natarajan Kannan, Patrick A Eyers. Biochem J 2015
Fiona P Bailey, Dominic P Byrne, Krishnadev Oruganty, Claire E Eyers, Christopher J Novotny, Kevan M Shokat, Natarajan Kannan, Patrick A Eyers. Biochem J 2015
20
Activation of Paired-homeobox gene PITX1 by del(5)(q31) in T-cell acute lymphoblastic leukemia.
Stefan Nagel, Letizia Venturini, Grzegorz K Przybylski, Piotr Grabarczyk, Björn Schneider, Corinna Meyer, Maren Kaufmann, Christian A Schmidt, Michaela Scherr, Hans G Drexler,[...]. Leuk Lymphoma 2011
Stefan Nagel, Letizia Venturini, Grzegorz K Przybylski, Piotr Grabarczyk, Björn Schneider, Corinna Meyer, Maren Kaufmann, Christian A Schmidt, Michaela Scherr, Hans G Drexler,[...]. Leuk Lymphoma 2011
20
Tribbles: a family of kinase-like proteins with potent signalling regulatory function.
Z Hegedus, A Czibula, E Kiss-Toth. Cell Signal 2007
Z Hegedus, A Czibula, E Kiss-Toth. Cell Signal 2007
20
A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila.
J Grosshans, E Wieschaus. Cell 2000
J Grosshans, E Wieschaus. Cell 2000
20
TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.
Ling Qi, Jose E Heredia, Judith Y Altarejos, Robert Screaton, Naomi Goebel, Sherry Niessen, Ian X Macleod, Chong Wee Liew, Rohit N Kulkarni, James Bain,[...]. Science 2006
Ling Qi, Jose E Heredia, Judith Y Altarejos, Robert Screaton, Naomi Goebel, Sherry Niessen, Ian X Macleod, Chong Wee Liew, Rohit N Kulkarni, James Bain,[...]. Science 2006
20
TRIB2 reinforces the oncogenic transcriptional program controlled by the TAL1 complex in T-cell acute lymphoblastic leukemia.
S H Tan, A W Y Yam, L N Lawton, R W J Wong, R A Young, A T Look, T Sanda. Leukemia 2016
S H Tan, A W Y Yam, L N Lawton, R W J Wong, R A Young, A T Look, T Sanda. Leukemia 2016
30
Competition between members of the tribbles pseudokinase protein family shapes their interactions with mitogen activated protein kinase pathways.
Hongtao Guan, Aban Shuaib, David Davila De Leon, Adrienn Angyal, Maria Salazar, Guillermo Velasco, Mike Holcombe, Steven K Dower, Endre Kiss-Toth. Sci Rep 2016
Hongtao Guan, Aban Shuaib, David Davila De Leon, Adrienn Angyal, Maria Salazar, Guillermo Velasco, Mike Holcombe, Steven K Dower, Endre Kiss-Toth. Sci Rep 2016
20
Ubiquitin E3 ligase SCF(β-TRCP) regulates TRIB2 stability in liver cancer cells.
Yongxia Qiao, Yue Zhang, Jiayi Wang. Biochem Biophys Res Commun 2013
Yongxia Qiao, Yue Zhang, Jiayi Wang. Biochem Biophys Res Commun 2013
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.