A citation-based method for searching scientific literature

Eri H Kobayashi, Takafumi Suzuki, Ryo Funayama, Takeshi Nagashima, Makiko Hayashi, Hiroki Sekine, Nobuyuki Tanaka, Takashi Moriguchi, Hozumi Motohashi, Keiko Nakayama, Masayuki Yamamoto. Nat Commun 2016
Times Cited: 589







List of co-cited articles
712 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis.
Rajesh K Thimmulappa, Hannah Lee, Tirumalai Rangasamy, Sekhar P Reddy, Masayuki Yamamoto, Thomas W Kensler, Shyam Biswal. J Clin Invest 2006
674
19

Nrf2 signaling pathway: Pivotal roles in inflammation.
Syed Minhaj Uddin Ahmed, Lin Luo, Akhileshwar Namani, Xiu Jun Wang, Xiuwen Tang. Biochim Biophys Acta Mol Basis Dis 2017
583
19

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
K Itoh, T Chiba, S Takahashi, T Ishii, K Igarashi, Y Katoh, T Oyake, N Hayashi, K Satoh, I Hatayama,[...]. Biochem Biophys Res Commun 1997
16

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism.
John D Hayes, Albena T Dinkova-Kostova. Trends Biochem Sci 2014
957
14

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P Jedrychowski, Ana S H Costa, Maureen Higgins, Emily Hams,[...]. Nature 2018
466
12

Role of nrf2 in oxidative stress and toxicity.
Qiang Ma. Annu Rev Pharmacol Toxicol 2013
11

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Evanna L Mills, Beth Kelly, Angela Logan, Ana S H Costa, Mukund Varma, Clare E Bryant, Panagiotis Tourlomousis, J Henry M Däbritz, Eyal Gottlieb, Isabel Latorre,[...]. Cell 2016
716
10

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases.
Antonio Cuadrado, Ana I Rojo, Geoffrey Wells, John D Hayes, Sharon P Cousin, William L Rumsey, Otis C Attucks, Stephen Franklin, Anna-Liisa Levonen, Thomas W Kensler,[...]. Nat Rev Drug Discov 2019
332
9

Transcriptional Regulation by Nrf2.
Claudia Tonelli, Iok In Christine Chio, David A Tuveson. Antioxid Redox Signal 2018
448
9

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.
Ashish Jain, Trond Lamark, Eva Sjøttem, Kenneth Bowitz Larsen, Jane Atesoh Awuh, Aud Øvervatn, Michael McMahon, John D Hayes, Terje Johansen. J Biol Chem 2010
839
8

Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development.
Natalia Robledinos-Antón, Raquel Fernández-Ginés, Gina Manda, Antonio Cuadrado. Oxid Med Cell Longev 2019
142
8

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis.
Masayuki Yamamoto, Thomas W Kensler, Hozumi Motohashi. Physiol Rev 2018
386
8

Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
Abhishek K Jha, Stanley Ching-Cheng Huang, Alexey Sergushichev, Vicky Lampropoulou, Yulia Ivanova, Ekaterina Loginicheva, Karina Chmielewski, Kelly M Stewart, Juliet Ashall, Bart Everts,[...]. Immunity 2015
759
8

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Vicky Lampropoulou, Alexey Sergushichev, Monika Bambouskova, Sharmila Nair, Emma E Vincent, Ekaterina Loginicheva, Luisa Cervantes-Barragan, Xiucui Ma, Stanley Ching-Cheng Huang, Takla Griss,[...]. Cell Metab 2016
466
8

Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.
Monika Bambouskova, Laurent Gorvel, Vicky Lampropoulou, Alexey Sergushichev, Ekaterina Loginicheva, Kendall Johnson, Daniel Korenfeld, Mary Elizabeth Mathyer, Hyeryun Kim, Li-Hao Huang,[...]. Nature 2018
207
8

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
G M Tannahill, A M Curtis, J Adamik, E M Palsson-McDermott, A F McGettrick, G Goel, C Frezza, N J Bernard, B Kelly, N H Foley,[...]. Nature 2013
8

Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Yoichiro Mitsuishi, Keiko Taguchi, Yukie Kawatani, Tatsuhiro Shibata, Toshihiro Nukiwa, Hiroyuki Aburatani, Masayuki Yamamoto, Hozumi Motohashi. Cancer Cell 2012
754
8

Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach.
Antonio Cuadrado, Gina Manda, Ahmed Hassan, María José Alcaraz, Coral Barbas, Andreas Daiber, Pietro Ghezzi, Rafael León, Manuela G López, Baldo Oliva,[...]. Pharmacol Rev 2018
205
7

Redox regulation by NRF2 in aging and disease.
Cody J Schmidlin, Matthew B Dodson, Lalitha Madhavan, Donna D Zhang. Free Radic Biol Med 2019
118
7



Transcription factors NRF2 and NF-κB are coordinated effectors of the Rho family, GTP-binding protein RAC1 during inflammation.
Antonio Cuadrado, Zaira Martín-Moldes, Jianping Ye, Isabel Lastres-Becker. J Biol Chem 2014
175
6

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
Akira Kobayashi, Moon-Il Kang, Hiromi Okawa, Makiko Ohtsuji, Yukari Zenke, Tomoki Chiba, Kazuhiko Igarashi, Masayuki Yamamoto. Mol Cell Biol 2004
6

The high Nrf2 expression in human acute myeloid leukemia is driven by NF-κB and underlies its chemo-resistance.
Stuart A Rushworth, Lyubov Zaitseva, Megan Y Murray, Niraj M Shah, Kristian M Bowles, David J MacEwan. Blood 2012
170
6

The KEAP1-NRF2 System in Cancer.
Keiko Taguchi, Masayuki Yamamoto. Front Oncol 2017
179
6

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
Masaaki Komatsu, Hirofumi Kurokawa, Satoshi Waguri, Keiko Taguchi, Akira Kobayashi, Yoshinobu Ichimura, Yu-Shin Sou, Izumi Ueno, Ayako Sakamoto, Kit I Tong,[...]. Nat Cell Biol 2010
6

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.
Ralf A Linker, De-Hyung Lee, Sarah Ryan, Anne M van Dam, Rebecca Conrad, Pradeep Bista, Weike Zeng, Xiaoping Hronowsky, Alex Buko, Sowmya Chollate,[...]. Brain 2011
652
6

Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes.
Annika S Axelsson, Emily Tubbs, Brig Mecham, Shaji Chacko, Hannah A Nenonen, Yunzhao Tang, Jed W Fahey, Jonathan M J Derry, Claes B Wollheim, Nils Wierup,[...]. Sci Transl Med 2017
125
6

Nrf2 regulates ROS production by mitochondria and NADPH oxidase.
Stjepana Kovac, Plamena R Angelova, Kira M Holmström, Ying Zhang, Albena T Dinkova-Kostova, Andrey Y Abramov. Biochim Biophys Acta 2015
269
6

Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration.
Kira M Holmström, Liam Baird, Ying Zhang, Iain Hargreaves, Annapurna Chalasani, John M Land, Lee Stanyer, Masayuki Yamamoto, Albena T Dinkova-Kostova, Andrey Y Abramov. Biol Open 2013
236
6

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain.
K Itoh, N Wakabayashi, Y Katoh, T Ishii, K Igarashi, J D Engel, M Yamamoto. Genes Dev 1999
6

Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis.
Tin Oo Khor, Mou-Tuan Huang, Ki Han Kwon, Jefferson Y Chan, Bandaru S Reddy, Ah-Ng Kong. Cancer Res 2006
332
6

Nuclear Factor E2-Related Factor-2 Negatively Regulates NLRP3 Inflammasome Activity by Inhibiting Reactive Oxygen Species-Induced NLRP3 Priming.
Xiuting Liu, Xin Zhang, Yang Ding, Wei Zhou, Lei Tao, Ping Lu, Yajing Wang, Rong Hu. Antioxid Redox Signal 2017
89
6

Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages.
Eva M Palsson-McDermott, Anne M Curtis, Gautam Goel, Mario A R Lauterbach, Frederick J Sheedy, Laura E Gleeson, Mirjam W M van den Bosch, Susan R Quinn, Raquel Domingo-Fernandez, Daniel G W Johnston,[...]. Cell Metab 2015
469
6

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
Alessandro Michelucci, Thekla Cordes, Jenny Ghelfi, Arnaud Pailot, Norbert Reiling, Oliver Goldmann, Tina Binz, André Wegner, Aravind Tallam, Antonio Rausell,[...]. Proc Natl Acad Sci U S A 2013
426
6

NRF2 and the Hallmarks of Cancer.
Montserrat Rojo de la Vega, Eli Chapman, Donna D Zhang. Cancer Cell 2018
399
6

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway.
Thomas W Kensler, Nobunao Wakabayashi, Shyam Biswal. Annu Rev Pharmacol Toxicol 2007
5

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways.
Joanna D Wardyn, Amy H Ponsford, Christopher M Sanderson. Biochem Soc Trans 2015
422
5

Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP axis.
Patricia Rada, Ana I Rojo, Nathalie Evrard-Todeschi, Nadia G Innamorato, Axelle Cotte, Tomasz Jaworski, Julio C Tobón-Velasco, Herman Devijver, María Flor García-Mayoral, Fred Van Leuven,[...]. Mol Cell Biol 2012
192
5

Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis.
Ralf Gold, Ludwig Kappos, Douglas L Arnold, Amit Bar-Or, Gavin Giovannoni, Krzysztof Selmaj, Carlo Tornatore, Marianne T Sweetser, Minhua Yang, Sarah I Sheikh,[...]. N Engl J Med 2012
5

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
Gina M DeNicola, Florian A Karreth, Timothy J Humpton, Aarthi Gopinathan, Cong Wei, Kristopher Frese, Dipti Mangal, Kenneth H Yu, Charles J Yeo, Eric S Calhoun,[...]. Nature 2011
5

Bardoxolone methyl and kidney function in CKD with type 2 diabetes.
Pablo E Pergola, Philip Raskin, Robert D Toto, Colin J Meyer, J Warren Huff, Eric B Grossman, Melissa Krauth, Stacey Ruiz, Paul Audhya, Heidi Christ-Schmidt,[...]. N Engl J Med 2011
596
5


Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha.
Brian N Chorley, Michelle R Campbell, Xuting Wang, Mehmet Karaca, Deepa Sambandan, Fatu Bangura, Peng Xue, Jingbo Pi, Steven R Kleeberger, Douglas A Bell. Nucleic Acids Res 2012
328
5

KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta.
Dung-Fang Lee, Hsu-Ping Kuo, Mo Liu, Chao-Kai Chou, Weiya Xia, Yi Du, Jia Shen, Chun-Te Chen, Longfei Huo, Ming-Chuan Hsu,[...]. Mol Cell 2009
245
5

A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
5

Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease.
Lauren E Tebay, Holly Robertson, Stephen T Durant, Steven R Vitale, Trevor M Penning, Albena T Dinkova-Kostova, John D Hayes. Free Radic Biol Med 2015
392
5

Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease.
Dick de Zeeuw, Tadao Akizawa, Paul Audhya, George L Bakris, Melanie Chin, Heidi Christ-Schmidt, Angie Goldsberry, Mark Houser, Melissa Krauth, Hiddo J Lambers Heerspink,[...]. N Engl J Med 2013
566
5

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer.
Emilia Kansanen, Suvi M Kuosmanen, Hanna Leinonen, Anna-Liisa Levonen. Redox Biol 2013
651
5

SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.
Patricia Rada, Ana I Rojo, Sudhir Chowdhry, Michael McMahon, John D Hayes, Antonio Cuadrado. Mol Cell Biol 2011
437
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.