Yuan Gao, Erhu Cao, David Julius, Yifan Cheng. Nature 2016
Times Cited: 469
Times Cited: 469
Times Cited
Times Co-cited
Similarity
TRPV1 structures in distinct conformations reveal activation mechanisms.
Erhu Cao, Maofu Liao, Yifan Cheng, David Julius. Nature 2013
Erhu Cao, Maofu Liao, Yifan Cheng, David Julius. Nature 2013
41
Structure of the TRPV1 ion channel determined by electron cryo-microscopy.
Maofu Liao, Erhu Cao, David Julius, Yifan Cheng. Nature 2013
Maofu Liao, Erhu Cao, David Julius, Yifan Cheng. Nature 2013
37
The capsaicin receptor: a heat-activated ion channel in the pain pathway.
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
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Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel.
Ying Yin, Son C Le, Allen L Hsu, Mario J Borgnia, Huanghe Yang, Seok-Yong Lee. Science 2019
Ying Yin, Son C Le, Allen L Hsu, Mario J Borgnia, Huanghe Yang, Seok-Yong Lee. Science 2019
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UCSF Chimera--a visualization system for exploratory research and analysis.
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Structure and gating mechanism of the transient receptor potential channel TRPV3.
Appu K Singh, Luke L McGoldrick, Alexander I Sobolevsky. Nat Struct Mol Biol 2018
Appu K Singh, Luke L McGoldrick, Alexander I Sobolevsky. Nat Struct Mol Biol 2018
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Conformational ensemble of the human TRPV3 ion channel.
Lejla Zubcevic, Mark A Herzik, Mengyu Wu, William F Borschel, Marscha Hirschi, Albert S Song, Gabriel C Lander, Seok-Yong Lee. Nat Commun 2018
Lejla Zubcevic, Mark A Herzik, Mengyu Wu, William F Borschel, Marscha Hirschi, Albert S Song, Gabriel C Lander, Seok-Yong Lee. Nat Commun 2018
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Cryo-electron microscopy structure of the TRPV2 ion channel.
Lejla Zubcevic, Mark A Herzik, Ben C Chung, Zhirui Liu, Gabriel C Lander, Seok-Yong Lee. Nat Struct Mol Biol 2016
Lejla Zubcevic, Mark A Herzik, Ben C Chung, Zhirui Liu, Gabriel C Lander, Seok-Yong Lee. Nat Struct Mol Biol 2016
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MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy.
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Shawn Q Zheng, Eugene Palovcak, Jean-Paul Armache, Kliment A Verba, Yifan Cheng, David A Agard. Nat Methods 2017
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Opening of the human epithelial calcium channel TRPV6.
Luke L McGoldrick, Appu K Singh, Kei Saotome, Maria V Yelshanskaya, Edward C Twomey, Robert A Grassucci, Alexander I Sobolevsky. Nature 2018
Luke L McGoldrick, Appu K Singh, Kei Saotome, Maria V Yelshanskaya, Edward C Twomey, Robert A Grassucci, Alexander I Sobolevsky. Nature 2018
15
Structure of the human TRPM4 ion channel in a lipid nanodisc.
Henriette E Autzen, Alexander G Myasnikov, Melody G Campbell, Daniel Asarnow, David Julius, Yifan Cheng. Science 2018
Henriette E Autzen, Alexander G Myasnikov, Melody G Campbell, Daniel Asarnow, David Julius, Yifan Cheng. Science 2018
15
Molecular mechanism of TRPV2 channel modulation by cannabidiol.
Ruth A Pumroy, Amrita Samanta, Yuhang Liu, Taylor Et Hughes, Siyuan Zhao, Yevgen Yudin, Tibor Rohacs, Seungil Han, Vera Y Moiseenkova-Bell. Elife 2019
Ruth A Pumroy, Amrita Samanta, Yuhang Liu, Taylor Et Hughes, Siyuan Zhao, Yevgen Yudin, Tibor Rohacs, Seungil Han, Vera Y Moiseenkova-Bell. Elife 2019
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Structural basis of temperature sensation by the TRP channel TRPV3.
Appu K Singh, Luke L McGoldrick, Lusine Demirkhanyan, Merfilius Leslie, Eleonora Zakharian, Alexander I Sobolevsky. Nat Struct Mol Biol 2019
Appu K Singh, Luke L McGoldrick, Lusine Demirkhanyan, Merfilius Leslie, Eleonora Zakharian, Alexander I Sobolevsky. Nat Struct Mol Biol 2019
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Structural insights on TRPV5 gating by endogenous modulators.
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Impaired nociception and pain sensation in mice lacking the capsaicin receptor.
M J Caterina, A Leffler, A B Malmberg, W J Martin, J Trafton, K R Petersen-Zeitz, M Koltzenburg, A I Basbaum, D Julius. Science 2000
M J Caterina, A Leffler, A B Malmberg, W J Martin, J Trafton, K R Petersen-Zeitz, M Koltzenburg, A I Basbaum, D Julius. Science 2000
13
Structural insights into TRPM8 inhibition and desensitization.
Melinda M Diver, Yifan Cheng, David Julius. Science 2019
Melinda M Diver, Yifan Cheng, David Julius. Science 2019
20
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination.
Ali Punjani, John L Rubinstein, David J Fleet, Marcus A Brubaker. Nat Methods 2017
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Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
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Structure of the full-length TRPV2 channel by cryo-EM.
Kevin W Huynh, Matthew R Cohen, Jiansen Jiang, Amrita Samanta, David T Lodowski, Z Hong Zhou, Vera Y Moiseenkova-Bell. Nat Commun 2016
Kevin W Huynh, Matthew R Cohen, Jiansen Jiang, Amrita Samanta, David T Lodowski, Z Hong Zhou, Vera Y Moiseenkova-Bell. Nat Commun 2016
12
The cloned capsaicin receptor integrates multiple pain-producing stimuli.
M Tominaga, M J Caterina, A B Malmberg, T A Rosen, H Gilbert, K Skinner, B E Raumann, A I Basbaum, D Julius. Neuron 1998
M Tominaga, M J Caterina, A B Malmberg, T A Rosen, H Gilbert, K Skinner, B E Raumann, A I Basbaum, D Julius. Neuron 1998
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Screening and large-scale expression of membrane proteins in mammalian cells for structural studies.
April Goehring, Chia-Hsueh Lee, Kevin H Wang, Jennifer Carlisle Michel, Derek P Claxton, Isabelle Baconguis, Thorsten Althoff, Suzanne Fischer, K Christopher Garcia, Eric Gouaux. Nat Protoc 2014
April Goehring, Chia-Hsueh Lee, Kevin H Wang, Jennifer Carlisle Michel, Derek P Claxton, Isabelle Baconguis, Thorsten Althoff, Suzanne Fischer, K Christopher Garcia, Eric Gouaux. Nat Protoc 2014
12
Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Candice E Paulsen, Jean-Paul Armache, Yuan Gao, Yifan Cheng, David Julius. Nature 2015
Candice E Paulsen, Jean-Paul Armache, Yuan Gao, Yifan Cheng, David Julius. Nature 2015
11
Structure of the cold- and menthol-sensing ion channel TRPM8.
Ying Yin, Mengyu Wu, Lejla Zubcevic, William F Borschel, Gabriel C Lander, Seok-Yong Lee. Science 2018
Ying Yin, Mengyu Wu, Lejla Zubcevic, William F Borschel, Gabriel C Lander, Seok-Yong Lee. Science 2018
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Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Appu K Singh, Kei Saotome, Luke L McGoldrick, Alexander I Sobolevsky. Nat Commun 2018
Appu K Singh, Kei Saotome, Luke L McGoldrick, Alexander I Sobolevsky. Nat Commun 2018
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Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel.
Fan Yang, Xian Xiao, Wei Cheng, Wei Yang, Peilin Yu, Zhenzhen Song, Vladimir Yarov-Yarovoy, Jie Zheng. Nat Chem Biol 2015
Fan Yang, Xian Xiao, Wei Cheng, Wei Yang, Peilin Yu, Zhenzhen Song, Vladimir Yarov-Yarovoy, Jie Zheng. Nat Chem Biol 2015
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Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
Yang Suo, Zilong Wang, Lejla Zubcevic, Allen L Hsu, Qianru He, Mario J Borgnia, Ru-Rong Ji, Seok-Yong Lee. Neuron 2020
Yang Suo, Zilong Wang, Lejla Zubcevic, Allen L Hsu, Qianru He, Mario J Borgnia, Ru-Rong Ji, Seok-Yong Lee. Neuron 2020
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Features and development of Coot.
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P Emsley, B Lohkamp, W G Scott, K Cowtan. Acta Crystallogr D Biol Crystallogr 2010
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The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism.
Hiroto Shimada, Tsukasa Kusakizako, T H Dung Nguyen, Tomohiro Nishizawa, Tomoya Hino, Makoto Tominaga, Osamu Nureki. Nat Struct Mol Biol 2020
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New tools for automated high-resolution cryo-EM structure determination in RELION-3.
Jasenko Zivanov, Takanori Nakane, Björn O Forsberg, Dari Kimanius, Wim Jh Hagen, Erik Lindahl, Sjors Hw Scheres. Elife 2018
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RELION: implementation of a Bayesian approach to cryo-EM structure determination.
Sjors H W Scheres. J Struct Biol 2012
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Crystal structure of the epithelial calcium channel TRPV6.
Kei Saotome, Appu K Singh, Maria V Yelshanskaya, Alexander I Sobolevsky. Nature 2016
Kei Saotome, Appu K Singh, Maria V Yelshanskaya, Alexander I Sobolevsky. Nature 2016
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Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function.
Jingjing Duan, Jian Li, Gui-Lan Chen, Yan Ge, Jieyu Liu, Kechen Xie, Xiaogang Peng, Wei Zhou, Jianing Zhong, Yixing Zhang,[...]. Sci Adv 2019
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Structural insight into TRPV5 channel function and modulation.
Shangyu Dang, Mark K van Goor, Daniel Asarnow, YongQiang Wang, David Julius, Yifan Cheng, Jenny van der Wijst. Proc Natl Acad Sci U S A 2019
Shangyu Dang, Mark K van Goor, Daniel Asarnow, YongQiang Wang, David Julius, Yifan Cheng, Jenny van der Wijst. Proc Natl Acad Sci U S A 2019
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Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms.
Zengqin Deng, Navid Paknejad, Grigory Maksaev, Monica Sala-Rabanal, Colin G Nichols, Richard K Hite, Peng Yuan. Nat Struct Mol Biol 2018
Zengqin Deng, Navid Paknejad, Grigory Maksaev, Monica Sala-Rabanal, Colin G Nichols, Richard K Hite, Peng Yuan. Nat Struct Mol Biol 2018
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Regulatory switch at the cytoplasmic interface controls TRPV channel gating.
Lejla Zubcevic, William F Borschel, Allen L Hsu, Mario J Borgnia, Seok-Yong Lee. Elife 2019
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Irritant-evoked activation and calcium modulation of the TRPA1 receptor.
Jianhua Zhao, John V Lin King, Candice E Paulsen, Yifan Cheng, David Julius. Nature 2020
Jianhua Zhao, John V Lin King, Candice E Paulsen, Yifan Cheng, David Julius. Nature 2020
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Gating of human TRPV3 in a lipid bilayer.
Zengqin Deng, Grigory Maksaev, Michael Rau, Zili Xie, Hongzhen Hu, James A J Fitzpatrick, Peng Yuan. Nat Struct Mol Biol 2020
Zengqin Deng, Grigory Maksaev, Michael Rau, Zili Xie, Hongzhen Hu, James A J Fitzpatrick, Peng Yuan. Nat Struct Mol Biol 2020
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Acid potentiation of the capsaicin receptor determined by a key extracellular site.
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Extracellular cap domain is an essential component of the TRPV1 gating mechanism.
Kirill D Nadezhdin, Arthur Neuberger, Yury A Nikolaev, Lyle A Murphy, Elena O Gracheva, Sviatoslav N Bagriantsev, Alexander I Sobolevsky. Nat Commun 2021
Kirill D Nadezhdin, Arthur Neuberger, Yury A Nikolaev, Lyle A Murphy, Elena O Gracheva, Sviatoslav N Bagriantsev, Alexander I Sobolevsky. Nat Commun 2021
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Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation.
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Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.
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Molecular basis for species-specific sensitivity to "hot" chili peppers.
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Structural basis for pharmacological modulation of the TRPC6 channel.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.