A citation-based method for searching scientific literature

Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
Times Cited: 1283







List of co-cited articles
772 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
27

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
24

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
19

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
16


Pore-forming activity and structural autoinhibition of the gasdermin family.
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
987
15

The inflammasomes.
Kate Schroder, Jurg Tschopp. Cell 2010
15

Inflammatory caspases are innate immune receptors for intracellular LPS.
Jianjin Shi, Yue Zhao, Yupeng Wang, Wenqing Gao, Jingjin Ding, Peng Li, Liyan Hu, Feng Shao. Nature 2014
15

A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
14

Non-canonical inflammasome activation targets caspase-11.
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
14

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
Raúl Muñoz-Planillo, Peter Kuffa, Giovanny Martínez-Colón, Brenna L Smith, Thekkelnaycke M Rajendiran, Gabriel Núñez. Immunity 2013
13

The gasdermins, a protein family executing cell death and inflammation.
Petr Broz, Pablo Pelegrín, Feng Shao. Nat Rev Immunol 2020
335
13

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
Wan-ting He, Haoqiang Wan, Lichen Hu, Pengda Chen, Xin Wang, Zhe Huang, Zhang-Hua Yang, Chuan-Qi Zhong, Jiahuai Han. Cell Res 2015
912
12

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.
Nathan Kelley, Devon Jeltema, Yanhui Duan, Yuan He. Int J Mol Sci 2019
722
12

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
Alvin Lu, Venkat Giri Magupalli, Jianbin Ruan, Qian Yin, Maninjay K Atianand, Matthijn R Vos, Gunnar F Schröder, Katherine A Fitzgerald, Hao Wu, Edward H Egelman. Cell 2014
711
11

The NLRP3 inflammasome: molecular activation and regulation to therapeutics.
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
11

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes.
Robin A Aglietti, Alberto Estevez, Aaron Gupta, Monica Gonzalez Ramirez, Peter S Liu, Nobuhiko Kayagaki, Claudio Ciferri, Vishva M Dixit, Erin C Dueber. Proc Natl Acad Sci U S A 2016
431
11

Inflammasome Complexes: Emerging Mechanisms and Effector Functions.
Vijay A K Rathinam, Katherine A Fitzgerald. Cell 2016
427
11

Activation and regulation of the inflammasomes.
Eicke Latz, T Sam Xiao, Andrea Stutz. Nat Rev Immunol 2013
11

Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors.
Yang Yang, Huanan Wang, Mohammed Kouadir, Houhui Song, Fushan Shi. Cell Death Dis 2019
458
10

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death.
Jianjin Shi, Wenqing Gao, Feng Shao. Trends Biochem Sci 2017
924
10

The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.
Charles L Evavold, Jianbin Ruan, Yunhao Tan, Shiyu Xia, Hao Wu, Jonathan C Kagan. Immunity 2018
458
10

Mechanism and Regulation of NLRP3 Inflammasome Activation.
Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
10

Inflammasomes: mechanism of action, role in disease, and therapeutics.
Haitao Guo, Justin B Callaway, Jenny P-Y Ting. Nat Med 2015
10

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.
Yuan He, Melody Y Zeng, Dahai Yang, Benny Motro, Gabriel Núñez. Nature 2016
530
10

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.
Corey Rogers, Teresa Fernandes-Alnemri, Lindsey Mayes, Diana Alnemri, Gino Cingolani, Emad S Alnemri. Nat Commun 2017
498
9

Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing.
Petr Broz, Jakob von Moltke, Jonathan W Jones, Russell E Vance, Denise M Monack. Cell Host Microbe 2010
397
9

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.
Dave Boucher, Mercedes Monteleone, Rebecca C Coll, Kaiwen W Chen, Connie M Ross, Jessica L Teo, Guillermo A Gomez, Caroline L Holley, Damien Bierschenk, Katryn J Stacey,[...]. J Exp Med 2018
217
9

Gout-associated uric acid crystals activate the NALP3 inflammasome.
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
9

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Rebecca C Coll, James R Hill, Christopher J Day, Alina Zamoshnikova, Dave Boucher, Nicholas L Massey, Jessica L Chitty, James A Fraser, Michael P Jennings, Avril A B Robertson,[...]. Nat Chem Biol 2019
281
9

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin.
Yupeng Wang, Wenqing Gao, Xuyan Shi, Jingjin Ding, Wang Liu, Huabin He, Kun Wang, Feng Shao. Nature 2017
813
9

DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia.
Darren C Johnson, Cornelius Y Taabazuing, Marian C Okondo, Ashley J Chui, Sahana D Rao, Fiona C Brown, Casie Reed, Elizabeth Peguero, Elisa de Stanchina, Alex Kentsis,[...]. Nat Med 2018
115
9

Mechanisms and functions of inflammasomes.
Mohamed Lamkanfi, Vishva M Dixit. Cell 2014
9

Pattern recognition receptors and inflammation.
Osamu Takeuchi, Shizuo Akira. Cell 2010
9

Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock.
Jon A Hagar, Daniel A Powell, Youssef Aachoui, Robert K Ernst, Edward A Miao. Science 2013
720
8



GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death.
Lorenzo Sborgi, Sebastian Rühl, Estefania Mulvihill, Joka Pipercevic, Rosalie Heilig, Henning Stahlberg, Christopher J Farady, Daniel J Müller, Petr Broz, Sebastian Hiller. EMBO J 2016
497
8

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Lorenzo Galluzzi, Ilio Vitale, Stuart A Aaronson, John M Abrams, Dieter Adam, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, Ivano Amelio, David W Andrews,[...]. Cell Death Differ 2018
8

Pyroptosis: host cell death and inflammation.
Tessa Bergsbaken, Susan L Fink, Brad T Cookson. Nat Rev Microbiol 2009
8

The inflammasomes: guardians of the body.
Fabio Martinon, Annick Mayor, Jürg Tschopp. Annu Rev Immunol 2009
8

Inflammasomes in health and disease.
Till Strowig, Jorge Henao-Mejia, Eran Elinav, Richard Flavell. Nature 2012
8

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
7

Caspase-1 interdomain linker cleavage is required for pyroptosis.
Daniel P Ball, Cornelius Y Taabazuing, Andrew R Griswold, Elizabeth L Orth, Sahana D Rao, Ilana B Kotliar, Lauren E Vostal, Darren C Johnson, Daniel A Bachovchin. Life Sci Alliance 2020
34
20

NINJ1 mediates plasma membrane rupture during lytic cell death.
Nobuhiko Kayagaki, Opher S Kornfeld, Bettina L Lee, Irma B Stowe, Karen O'Rourke, Qingling Li, Wendy Sandoval, Donghong Yan, Jing Kang, Min Xu,[...]. Nature 2021
103
7

Noncanonical inflammasome activation by intracellular LPS independent of TLR4.
Nobuhiko Kayagaki, Michael T Wong, Irma B Stowe, Sree Ranjani Ramani, Lino C Gonzalez, Sachiko Akashi-Takamura, Kensuke Miyake, Juan Zhang, Wyne P Lee, Artur Muszyński,[...]. Science 2013
893
7

Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection.
Joseph Sarhan, Beiyun C Liu, Hayley I Muendlein, Peng Li, Rachael Nilson, Amy Y Tang, Anthony Rongvaux, Stephen C Bunnell, Feng Shao, Douglas R Green,[...]. Proc Natl Acad Sci U S A 2018
263
7

Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.
L Robert Hollingsworth, Liron David, Yang Li, Andrew R Griswold, Jianbin Ruan, Humayun Sharif, Pietro Fontana, Elizabeth L Orth-He, Tian-Min Fu, Daniel A Bachovchin,[...]. Nat Commun 2021
20
35

FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.
Jun Jacob Hu, Xing Liu, Shiyu Xia, Zhibin Zhang, Ying Zhang, Jingxia Zhao, Jianbin Ruan, Xuemei Luo, Xiwen Lou, Yang Bai,[...]. Nat Immunol 2020
187
7

Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Pontus Orning, Dan Weng, Kristian Starheim, Dmitry Ratner, Zachary Best, Bettina Lee, Alexandria Brooks, Shiyu Xia, Hao Wu, Michelle A Kelliher,[...]. Science 2018
341
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.