A citation-based method for searching scientific literature

Randy Strong, Richard A Miller, Adam Antebi, Clinton M Astle, Molly Bogue, Martin S Denzel, Elizabeth Fernandez, Kevin Flurkey, Karyn L Hamilton, Dudley W Lamming, Martin A Javors, João Pedro de Magalhães, Paul Anthony Martinez, Joe M McCord, Benjamin F Miller, Michael Müller, James F Nelson, Juliet Ndukum, G Ed Rainger, Arlan Richardson, David M Sabatini, Adam B Salmon, James W Simpkins, Wilma T Steegenga, Nancy L Nadon, David E Harrison. Aging Cell 2016
Times Cited: 131







List of co-cited articles
1156 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males.
David E Harrison, Randy Strong, David B Allison, Bruce N Ames, Clinton M Astle, Hani Atamna, Elizabeth Fernandez, Kevin Flurkey, Martin A Javors, Nancy L Nadon,[...]. Aging Cell 2014
187
43

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
David E Harrison, Randy Strong, Zelton Dave Sharp, James F Nelson, Clinton M Astle, Kevin Flurkey, Nancy L Nadon, J Erby Wilkinson, Krystyna Frenkel, Christy S Carter,[...]. Nature 2009
42

Metformin improves healthspan and lifespan in mice.
Alejandro Martin-Montalvo, Evi M Mercken, Sarah J Mitchell, Hector H Palacios, Patricia L Mote, Morten Scheibye-Knudsen, Ana P Gomes, Theresa M Ward, Robin K Minor, Marie-José Blouin,[...]. Nat Commun 2013
662
34

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.
Richard A Miller, David E Harrison, C M Astle, Joseph A Baur, Angela Rodriguez Boyd, Rafael de Cabo, Elizabeth Fernandez, Kevin Flurkey, Martin A Javors, James F Nelson,[...]. J Gerontol A Biol Sci Med Sci 2011
572
32

Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction.
Richard A Miller, David E Harrison, Clinton M Astle, Elizabeth Fernandez, Kevin Flurkey, Melissa Han, Martin A Javors, Xinna Li, Nancy L Nadon, James F Nelson,[...]. Aging Cell 2014
290
29

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
26

Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice.
Randy Strong, Richard A Miller, Clinton M Astle, Robert A Floyd, Kevin Flurkey, Kenneth L Hensley, Martin A Javors, Christiaan Leeuwenburgh, James F Nelson, Ennio Ongini,[...]. Aging Cell 2008
189
23

Metformin as a Tool to Target Aging.
Nir Barzilai, Jill P Crandall, Stephen B Kritchevsky, Mark A Espeland. Cell Metab 2016
405
22


Geroscience: linking aging to chronic disease.
Brian K Kennedy, Shelley L Berger, Anne Brunet, Judith Campisi, Ana Maria Cuervo, Elissa S Epel, Claudio Franceschi, Gordon J Lithgow, Richard I Morimoto, Jeffrey E Pessin,[...]. Cell 2014
801
16

Rapamycin slows aging in mice.
John E Wilkinson, Lisa Burmeister, Susan V Brooks, Chi-Chao Chan, Sabrina Friedline, David E Harrison, James F Hejtmancik, Nancy Nadon, Randy Strong, Lauren K Wood,[...]. Aging Cell 2012
391
16

Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
Dudley W Lamming, Lan Ye, Pekka Katajisto, Marcus D Goncalves, Maki Saitoh, Deanna M Stevens, James G Davis, Adam B Salmon, Arlan Richardson, Rexford S Ahima,[...]. Science 2012
713
14

Resveratrol improves health and survival of mice on a high-calorie diet.
Joseph A Baur, Kevin J Pearson, Nathan L Price, Hamish A Jamieson, Carles Lerin, Avash Kalra, Vinayakumar V Prabhu, Joanne S Allard, Guillermo Lopez-Lluch, Kaitlyn Lewis,[...]. Nature 2006
13

17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization.
Michael B Stout, Frederik J Steyn, Michael J Jurczak, Joao-Paulo G Camporez, Yi Zhu, John R Hawse, Diana Jurk, Allyson K Palmer, Ming Xu, Tamar Pirtskhalava,[...]. J Gerontol A Biol Sci Med Sci 2017
51
25

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice.
Alessandro Bitto, Takashi K Ito, Victor V Pineda, Nicolas J LeTexier, Heather Z Huang, Elissa Sutlief, Herman Tung, Nicholas Vizzini, Belle Chen, Kaleb Smith,[...]. Elife 2016
145
13

Acarbose improves health and lifespan in aging HET3 mice.
David E Harrison, Randy Strong, Silvestre Alavez, Clinton Michael Astle, John DiGiovanni, Elizabeth Fernandez, Kevin Flurkey, Michael Garratt, Jonathan A L Gelfond, Martin A Javors,[...]. Aging Cell 2019
31
41

Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.
Filipe Cabreiro, Catherine Au, Kit-Yi Leung, Nuria Vergara-Irigaray, Helena M Cochemé, Tahereh Noori, David Weinkove, Eugene Schuster, Nicholas D E Greene, David Gems. Cell 2013
494
12

Rapamycin extends life and health in C57BL/6 mice.
Yiqiang Zhang, Alex Bokov, John Gelfond, Vanessa Soto, Yuji Ikeno, Gene Hubbard, Vivian Diaz, Lauren Sloane, Keith Maslin, Stephen Treaster,[...]. J Gerontol A Biol Sci Med Sci 2014
179
12

Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls.
C A Bannister, S E Holden, S Jenkins-Jones, C Ll Morgan, J P Halcox, G Schernthaner, J Mukherjee, C J Currie. Diabetes Obes Metab 2014
166
11



Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice.
Randy Strong, Richard A Miller, Clinton M Astle, Joseph A Baur, Rafael de Cabo, Elizabeth Fernandez, Wen Guo, Martin Javors, James L Kirkland, James F Nelson,[...]. J Gerontol A Biol Sci Med Sci 2013
118
11

mTOR is a key modulator of ageing and age-related disease.
Simon C Johnson, Peter S Rabinovitch, Matt Kaeberlein. Nature 2013
924
11

An Aging Interventions Testing Program: study design and interim report.
Richard A Miller, David E Harrison, Clinton M Astle, Robert A Floyd, Kevin Flurkey, Kenneth L Hensley, Martin A Javors, Christiaan Leeuwenburgh, James F Nelson, Ennio Ongini,[...]. Aging Cell 2007
119
11

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.
Megan N Roberts, Marita A Wallace, Alexey A Tomilov, Zeyu Zhou, George R Marcotte, Dianna Tran, Gabriella Perez, Elena Gutierrez-Casado, Shinichiro Koike, Trina A Knotts,[...]. Cell Metab 2017
153
10

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Darren J Baker, Bennett G Childs, Matej Durik, Melinde E Wijers, Cynthia J Sieben, Jian Zhong, Rachel A Saltness, Karthik B Jeganathan, Grace Casaclang Verzosa, Abdulmohammad Pezeshki,[...]. Nature 2016
10

Metformin slows down aging and extends life span of female SHR mice.
Vladimir N Anisimov, Lev M Berstein, Peter A Egormin, Tatiana S Piskunova, Irina G Popovich, Mark A Zabezhinski, Margarita L Tyndyk, Maria V Yurova, Irina G Kovalenko, Tatiana E Poroshina,[...]. Cell Cycle 2008
214
10

Caloric restriction improves health and survival of rhesus monkeys.
Julie A Mattison, Ricki J Colman, T Mark Beasley, David B Allison, Joseph W Kemnitz, George S Roth, Donald K Ingram, Richard Weindruch, Rafael de Cabo, Rozalyn M Anderson. Nat Commun 2017
333
10

Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat Med 2018
554
10

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.
Sarah J Mitchell, Julio Madrigal-Matute, Morten Scheibye-Knudsen, Evandro Fang, Miguel Aon, José A González-Reyes, Sonia Cortassa, Susmita Kaushik, Marta Gonzalez-Freire, Bindi Patel,[...]. Cell Metab 2016
191
9

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
Kevin J Pearson, Joseph A Baur, Kaitlyn N Lewis, Leonid Peshkin, Nathan L Price, Nazar Labinskyy, William R Swindell, Davida Kamara, Robin K Minor, Evelyn Perez,[...]. Cell Metab 2008
797
9

Sex Differences in Lifespan.
Steven N Austad, Kathleen E Fischer. Cell Metab 2016
174
9

Extending healthy life span--from yeast to humans.
Luigi Fontana, Linda Partridge, Valter D Longo. Science 2010
9

Male lifespan extension with 17-α estradiol is linked to a sex-specific metabolomic response modulated by gonadal hormones in mice.
Michael Garratt, Kim A Lagerborg, Yi-Miau Tsai, Andrzej Galecki, Mohit Jain, Richard A Miller. Aging Cell 2018
16
56

If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice.
Vladimir N Anisimov, Lev M Berstein, Irina G Popovich, Mark A Zabezhinski, Peter A Egormin, Tatiana S Piskunova, Anna V Semenchenko, Margarita L Tyndyk, Maria N Yurova, Irina G Kovalenko,[...]. Aging (Albany NY) 2011
172
9

Interventions to Slow Aging in Humans: Are We Ready?
Valter D Longo, Adam Antebi, Andrzej Bartke, Nir Barzilai, Holly M Brown-Borg, Calogero Caruso, Tyler J Curiel, Rafael de Cabo, Claudio Franceschi, David Gems,[...]. Aging Cell 2015
292
9


Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.
Sarah J Mitchell, Michel Bernier, Miguel A Aon, Sonia Cortassa, Eun Young Kim, Evandro F Fang, Hector H Palacios, Ahmed Ali, Ignacio Navas-Enamorado, Andrea Di Francesco,[...]. Cell Metab 2018
112
9

mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells.
Chong Chen, Yu Liu, Yang Liu, Pan Zheng. Sci Signal 2009
401
9

Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2.
Wouter De Haes, Lotte Frooninckx, Roel Van Assche, Arne Smolders, Geert Depuydt, Johan Billen, Bart P Braeckman, Liliane Schoofs, Liesbet Temmerman. Proc Natl Acad Sci U S A 2014
181
9

Glycine supplementation extends lifespan of male and female mice.
Richard A Miller, David E Harrison, C Michael Astle, Molly A Bogue, Joel Brind, Elizabeth Fernandez, Kevin Flurkey, Martin Javors, Warren Ladiges, Christiaan Leeuwenburgh,[...]. Aging Cell 2019
21
42

Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice.
John C Newman, Anthony J Covarrubias, Minghao Zhao, Xinxing Yu, Philipp Gut, Che-Ping Ng, Yu Huang, Saptarsi Haldar, Eric Verdin. Cell Metab 2017
154
9

mTOR inhibition improves immune function in the elderly.
Joan B Mannick, Giuseppe Del Giudice, Maria Lattanzi, Nicholas M Valiante, Jens Praestgaard, Baisong Huang, Michael A Lonetto, Holden T Maecker, John Kovarik, Simon Carson,[...]. Sci Transl Med 2014
349
9

SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass.
Evi M Mercken, Sarah J Mitchell, Alejandro Martin-Montalvo, Robin K Minor, Maria Almeida, Ana P Gomes, Morten Scheibye-Knudsen, Hector H Palacios, Jordan J Licata, Yongqing Zhang,[...]. Aging Cell 2014
132
8

17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior.
Frederik J Steyn, Shyuan T Ngo, Vicky Ping Chen, Lora C Bailey-Downs, Teresa Y Xie, Martin Ghadami, Stephen Brimijoin, Willard M Freeman, Marcelo Rubinstein, Malcolm J Low,[...]. Aging Cell 2018
18
44

NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice.
Hongbo Zhang, Dongryeol Ryu, Yibo Wu, Karim Gariani, Xu Wang, Peiling Luan, Davide D'Amico, Eduardo R Ropelle, Matthias P Lutolf, Ruedi Aebersold,[...]. Science 2016
514
8

Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome.
Wilson C Fok, Yidong Chen, Alex Bokov, Yiqiang Zhang, Adam B Salmon, Vivian Diaz, Martin Javors, William H Wood, Yongqing Zhang, Kevin G Becker,[...]. PLoS One 2014
81
9

Rapamycin extends murine lifespan but has limited effects on aging.
Frauke Neff, Diana Flores-Dominguez, Devon P Ryan, Marion Horsch, Susanne Schröder, Thure Adler, Luciana Caminha Afonso, Juan Antonio Aguilar-Pimentel, Lore Becker, Lillian Garrett,[...]. J Clin Invest 2013
230
8

Late-life rapamycin treatment reverses age-related heart dysfunction.
James M Flynn, Monique N O'Leary, Christopher A Zambataro, Emmeline C Academia, Michael P Presley, Brittany J Garrett, Artem Zykovich, Sean D Mooney, Randy Strong, Clifford J Rosen,[...]. Aging Cell 2013
176
8



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.