Nandhitha Subramanian, Amanda J Scopelitti, Jane E Carland, Renae M Ryan, Megan L O'Mara, Robert J Vandenberg. PLoS One 2016
Times Cited: 15
Times Cited: 15
Times Cited
Times Co-cited
Similarity
X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
Harini Krishnamurthy, Eric Gouaux. Nature 2012
Harini Krishnamurthy, Eric Gouaux. Nature 2012
60
Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters.
Atsuko Yamashita, Satinder K Singh, Toshimitsu Kawate, Yan Jin, Eric Gouaux. Nature 2005
Atsuko Yamashita, Satinder K Singh, Toshimitsu Kawate, Yan Jin, Eric Gouaux. Nature 2005
53
X-ray structures and mechanism of the human serotonin transporter.
Jonathan A Coleman, Evan M Green, Eric Gouaux. Nature 2016
Jonathan A Coleman, Evan M Green, Eric Gouaux. Nature 2016
53
X-ray structure of dopamine transporter elucidates antidepressant mechanism.
Aravind Penmatsa, Kevin H Wang, Eric Gouaux. Nature 2013
Aravind Penmatsa, Kevin H Wang, Eric Gouaux. Nature 2013
53
Glycine transport inhibitors for the treatment of pain.
Robert J Vandenberg, Renae M Ryan, Jane E Carland, Wendy L Imlach, Macdonald J Christie. Trends Pharmacol Sci 2014
Robert J Vandenberg, Renae M Ryan, Jane E Carland, Wendy L Imlach, Macdonald J Christie. Trends Pharmacol Sci 2014
53
Neuronal and glial glycine transporters have different stoichiometries.
M J Roux, S Supplisson. Neuron 2000
M J Roux, S Supplisson. Neuron 2000
46
Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2.
Jane E Carland, Michael Thomas, Shannon N Mostyn, Nandhitha Subramanian, Megan L O'Mara, Renae M Ryan, Robert J Vandenberg. ACS Chem Neurosci 2018
Jane E Carland, Michael Thomas, Shannon N Mostyn, Nandhitha Subramanian, Megan L O'Mara, Renae M Ryan, Robert J Vandenberg. ACS Chem Neurosci 2018
46
Extracellular loops 2 and 4 of GLYT2 are required for N-arachidonylglycine inhibition of glycine transport.
Amelia R Edington, Audra A McKinzie, Aaron J Reynolds, Michael Kassiou, Renae M Ryan, Robert J Vandenberg. J Biol Chem 2009
Amelia R Edington, Audra A McKinzie, Aaron J Reynolds, Michael Kassiou, Renae M Ryan, Robert J Vandenberg. J Biol Chem 2009
40
Why glycine transporters have different stoichiometries.
Stéphane Supplisson, Michel J Roux. FEBS Lett 2002
Stéphane Supplisson, Michel J Roux. FEBS Lett 2002
33
Endocytosis of the neuronal glycine transporter GLYT2: role of membrane rafts and protein kinase C-dependent ubiquitination.
Jaime de Juan-Sanz, Francisco Zafra, Beatriz López-Corcuera, Carmen Aragón. Traffic 2011
Jaime de Juan-Sanz, Francisco Zafra, Beatriz López-Corcuera, Carmen Aragón. Traffic 2011
33
Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality.
Jesús Gomeza, Koji Ohno, Swen Hülsmann, Wencke Armsen, Volker Eulenburg, Diethelm W Richter, Bodo Laube, Heinrich Betz. Neuron 2003
Jesús Gomeza, Koji Ohno, Swen Hülsmann, Wencke Armsen, Volker Eulenburg, Diethelm W Richter, Bodo Laube, Heinrich Betz. Neuron 2003
33
A novel dominant hyperekplexia mutation Y705C alters trafficking and biochemical properties of the presynaptic glycine transporter GlyT2.
Cecilio Giménez, Gonzalo Pérez-Siles, Jaime Martínez-Villarreal, Esther Arribas-González, Esperanza Jiménez, Enrique Núñez, Jaime de Juan-Sanz, Enrique Fernández-Sánchez, Noemí García-Tardón, Ignacio Ibáñez,[...]. J Biol Chem 2012
Cecilio Giménez, Gonzalo Pérez-Siles, Jaime Martínez-Villarreal, Esther Arribas-González, Esperanza Jiménez, Enrique Núñez, Jaime de Juan-Sanz, Enrique Fernández-Sánchez, Noemí García-Tardón, Ignacio Ibáñez,[...]. J Biol Chem 2012
33
Molecular basis of the differential interaction with lithium of glycine transporters GLYT1 and GLYT2.
Gonzalo Pérez-Siles, Antonio Morreale, Alejandra Leo-Macías, Guillermo Pita, Angel R Ortíz, Carmen Aragón, Beatriz López-Corcuera. J Neurochem 2011
Gonzalo Pérez-Siles, Antonio Morreale, Alejandra Leo-Macías, Guillermo Pita, Angel R Ortíz, Carmen Aragón, Beatriz López-Corcuera. J Neurochem 2011
33
Glycine transporters as novel therapeutic targets in schizophrenia, alcohol dependence and pain.
Robert J Harvey, Benjamin K Yee. Nat Rev Drug Discov 2013
Robert J Harvey, Benjamin K Yee. Nat Rev Drug Discov 2013
33
Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease.
Mark I Rees, Kirsten Harvey, Brian R Pearce, Seo-Kyung Chung, Ian C Duguid, Philip Thomas, Sarah Beatty, Gail E Graham, Linlea Armstrong, Rita Shiang,[...]. Nat Genet 2006
Mark I Rees, Kirsten Harvey, Brian R Pearce, Seo-Kyung Chung, Ian C Duguid, Philip Thomas, Sarah Beatty, Gail E Graham, Linlea Armstrong, Rita Shiang,[...]. Nat Genet 2006
33
Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue.
Yongfang Zhao, Daniel S Terry, Lei Shi, Matthias Quick, Harel Weinstein, Scott C Blanchard, Jonathan A Javitch. Nature 2011
Yongfang Zhao, Daniel S Terry, Lei Shi, Matthias Quick, Harel Weinstein, Scott C Blanchard, Jonathan A Javitch. Nature 2011
33
N-Arachidonyl-glycine inhibits the glycine transporter, GLYT2a.
Amy L Wiles, Rhonda-Jo Pearlman, Mari Rosvall, Karin R Aubrey, Robert J Vandenberg. J Neurochem 2006
Amy L Wiles, Rhonda-Jo Pearlman, Mari Rosvall, Karin R Aubrey, Robert J Vandenberg. J Neurochem 2006
33
A direct interaction of cholesterol with the dopamine transporter prevents its out-to-inward transition.
Talia Zeppelin, Lucy Kate Ladefoged, Steffen Sinning, Xavier Periole, Birgit Schiøtt. PLoS Comput Biol 2018
Talia Zeppelin, Lucy Kate Ladefoged, Steffen Sinning, Xavier Periole, Birgit Schiøtt. PLoS Comput Biol 2018
33
X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine.
Aravind Penmatsa, Kevin H Wang, Eric Gouaux. Nat Struct Mol Biol 2015
Aravind Penmatsa, Kevin H Wang, Eric Gouaux. Nat Struct Mol Biol 2015
33
SLC6 neurotransmitter transporters: structure, function, and regulation.
Anders S Kristensen, Jacob Andersen, Trine N Jørgensen, Lena Sørensen, Jacob Eriksen, Claus J Loland, Kristian Strømgaard, Ulrik Gether. Pharmacol Rev 2011
Anders S Kristensen, Jacob Andersen, Trine N Jørgensen, Lena Sørensen, Jacob Eriksen, Claus J Loland, Kristian Strømgaard, Ulrik Gether. Pharmacol Rev 2011
33
The first potent and selective inhibitors of the glycine transporter type 2.
W L Caulfield, I T Collie, R S Dickins, O Epemolu, R McGuire, D R Hill, G McVey, J R Morphy, Z Rankovic, H Sundaram. J Med Chem 2001
W L Caulfield, I T Collie, R S Dickins, O Epemolu, R McGuire, D R Hill, G McVey, J R Morphy, Z Rankovic, H Sundaram. J Med Chem 2001
33
Spinal antiallodynia action of glycine transporter inhibitors in neuropathic pain models in mice.
Katsuya Morita, Naoyo Motoyama, Tomoya Kitayama, Norimitsu Morioka, Koki Kifune, Toshihiro Dohi. J Pharmacol Exp Ther 2008
Katsuya Morita, Naoyo Motoyama, Tomoya Kitayama, Norimitsu Morioka, Koki Kifune, Toshihiro Dohi. J Pharmacol Exp Ther 2008
33
Molecular basis for substrate discrimination by glycine transporters.
Robert J Vandenberg, Kim Shaddick, Pengchu Ju. J Biol Chem 2007
Robert J Vandenberg, Kim Shaddick, Pengchu Ju. J Biol Chem 2007
26
The role of N-glycosylation in transport to the plasma membrane and sorting of the neuronal glycine transporter GLYT2.
R Martínez-Maza, I Poyatos, B López-Corcuera, E N úñez, C Giménez, F Zafra, C Aragón. J Biol Chem 2001
R Martínez-Maza, I Poyatos, B López-Corcuera, E N úñez, C Giménez, F Zafra, C Aragón. J Biol Chem 2001
26
Molecular basis of the dominant negative effect of a glycine transporter 2 mutation associated with hyperekplexia.
Esther Arribas-González, Jaime de Juan-Sanz, Carmen Aragón, Beatriz López-Corcuera. J Biol Chem 2015
Esther Arribas-González, Jaime de Juan-Sanz, Carmen Aragón, Beatriz López-Corcuera. J Biol Chem 2015
26
26
An aspartate residue in the external vestibule of GLYT2 (glycine transporter 2) controls cation access and transport coupling.
Gonzalo Pérez-Siles, Enrique Núñez, Antonio Morreale, Esperanza Jiménez, Alejandra Leo-Macías, Guillermo Pita, Francesca Cherubino, Rachele Sangaletti, Elena Bossi, Angel R Ortíz,[...]. Biochem J 2012
Gonzalo Pérez-Siles, Enrique Núñez, Antonio Morreale, Esperanza Jiménez, Alejandra Leo-Macías, Guillermo Pita, Francesca Cherubino, Rachele Sangaletti, Elena Bossi, Angel R Ortíz,[...]. Biochem J 2012
30
The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction.
Gary Rudnick, Reinhard Krämer, Randy D Blakely, Dennis L Murphy, Francois Verrey. Pflugers Arch 2014
Gary Rudnick, Reinhard Krämer, Randy D Blakely, Dennis L Murphy, Francois Verrey. Pflugers Arch 2014
26
Differential properties of two stably expressed brain-specific glycine transporters.
B López-Corcuera, R Martínez-Maza, E Núñez, M Roux, S Supplisson, C Aragón. J Neurochem 1998
B López-Corcuera, R Martínez-Maza, E Núñez, M Roux, S Supplisson, C Aragón. J Neurochem 1998
26
Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition.
Jesús Gomeza, Swen Hülsmann, Koji Ohno, Volker Eulenburg, Katalin Szöke, Diethelm Richter, Heinrich Betz. Neuron 2003
Jesús Gomeza, Swen Hülsmann, Koji Ohno, Volker Eulenburg, Katalin Szöke, Diethelm Richter, Heinrich Betz. Neuron 2003
26
Common folds and transport mechanisms of secondary active transporters.
Yigong Shi. Annu Rev Biophys 2013
Yigong Shi. Annu Rev Biophys 2013
26
Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome.
J A Morrow, I T Collie, D R Dunbar, G B Walker, M Shahid, D R Hill. FEBS Lett 1998
J A Morrow, I T Collie, D R Dunbar, G B Walker, M Shahid, D R Hill. FEBS Lett 1998
26
Modulation of Glycine-Mediated Spinal Neurotransmission for the Treatment of Chronic Pain.
Christopher L Cioffi. J Med Chem 2018
Christopher L Cioffi. J Med Chem 2018
26
Reversible inhibition of the glycine transporter GlyT2 circumvents acute toxicity while preserving efficacy in the treatment of pain.
A Mingorance-Le Meur, P Ghisdal, B Mullier, P De Ron, P Downey, C Van Der Perren, V Declercq, S Cornelis, M Famelart, J Van Asperen,[...]. Br J Pharmacol 2013
A Mingorance-Le Meur, P Ghisdal, B Mullier, P De Ron, P Downey, C Van Der Perren, V Declercq, S Cornelis, M Famelart, J Van Asperen,[...]. Br J Pharmacol 2013
26
Mechanism for alternating access in neurotransmitter transporters.
Lucy R Forrest, Yuan-Wei Zhang, Miriam T Jacobs, Joan Gesmonde, Li Xie, Barry H Honig, Gary Rudnick. Proc Natl Acad Sci U S A 2008
Lucy R Forrest, Yuan-Wei Zhang, Miriam T Jacobs, Joan Gesmonde, Li Xie, Barry H Honig, Gary Rudnick. Proc Natl Acad Sci U S A 2008
26
Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Kevin H Wang, Aravind Penmatsa, Eric Gouaux. Nature 2015
Kevin H Wang, Aravind Penmatsa, Eric Gouaux. Nature 2015
26
Development of an N-Acyl Amino Acid That Selectively Inhibits the Glycine Transporter 2 To Produce Analgesia in a Rat Model of Chronic Pain.
Shannon N Mostyn, Tristan Rawling, Sarasa Mohammadi, Susan Shimmon, Zachary J Frangos, Subhodeep Sarker, Arsalan Yousuf, Irina Vetter, Renae M Ryan, Macdonald J Christie,[...]. J Med Chem 2019
Shannon N Mostyn, Tristan Rawling, Sarasa Mohammadi, Susan Shimmon, Zachary J Frangos, Subhodeep Sarker, Arsalan Yousuf, Irina Vetter, Renae M Ryan, Macdonald J Christie,[...]. J Med Chem 2019
26
Lipid-Based Inhibitors Act Directly on GlyT2.
Alexandra Schumann-Gillett, Megan L O'Mara. ACS Chem Neurosci 2019
Alexandra Schumann-Gillett, Megan L O'Mara. ACS Chem Neurosci 2019
57
Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2.
Shannon N Mostyn, Jane E Carland, Susan Shimmon, Renae M Ryan, Tristan Rawling, Robert J Vandenberg. ACS Chem Neurosci 2017
Shannon N Mostyn, Jane E Carland, Susan Shimmon, Renae M Ryan, Tristan Rawling, Robert J Vandenberg. ACS Chem Neurosci 2017
26
Oleoyl-L-carnitine inhibits glycine transport by GlyT2.
J E Carland, R E Mansfield, R M Ryan, R J Vandenberg. Br J Pharmacol 2013
J E Carland, R E Mansfield, R M Ryan, R J Vandenberg. Br J Pharmacol 2013
26
Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics.
Shannon N Mostyn, Katie A Wilson, Alexandra Schumann-Gillett, Zachary J Frangos, Susan Shimmon, Tristan Rawling, Renae M Ryan, Megan L O'Mara, Robert J Vandenberg. Elife 2019
Shannon N Mostyn, Katie A Wilson, Alexandra Schumann-Gillett, Zachary J Frangos, Susan Shimmon, Tristan Rawling, Renae M Ryan, Megan L O'Mara, Robert J Vandenberg. Elife 2019
26
Shared Molecular Mechanisms of Membrane Transporters.
David Drew, Olga Boudker. Annu Rev Biochem 2016
David Drew, Olga Boudker. Annu Rev Biochem 2016
20
Neurotransmitter transporters: molecular function of important drug targets.
Ulrik Gether, Peter H Andersen, Orla M Larsson, Arne Schousboe. Trends Pharmacol Sci 2006
Ulrik Gether, Peter H Andersen, Orla M Larsson, Arne Schousboe. Trends Pharmacol Sci 2006
20
Lidocaine metabolites inhibit glycine transporter 1: a novel mechanism for the analgesic action of systemic lidocaine?
Robert Werdehausen, David Kremer, Timo Brandenburger, Lukas Schlösser, Janusz Jadasz, Patrick Küry, Inge Bauer, Carmen Aragón, Volker Eulenburg, Henning Hermanns. Anesthesiology 2012
Robert Werdehausen, David Kremer, Timo Brandenburger, Lukas Schlösser, Janusz Jadasz, Patrick Küry, Inge Bauer, Carmen Aragón, Volker Eulenburg, Henning Hermanns. Anesthesiology 2012
20
Oligomerization of neurotransmitter transporters: a ticket from the endoplasmic reticulum to the plasma membrane.
H Farhan, M Freissmuth, H H Sitte. Handb Exp Pharmacol 2006
H Farhan, M Freissmuth, H H Sitte. Handb Exp Pharmacol 2006
20
The rocking bundle: a mechanism for ion-coupled solute flux by symmetrical transporters.
Lucy R Forrest, Gary Rudnick. Physiology (Bethesda) 2009
Lucy R Forrest, Gary Rudnick. Physiology (Bethesda) 2009
20
Localization of the GLYT1 glycine transporter at glutamatergic synapses in the rat brain.
Beatriz Cubelos, Cecilio Giménez, Francisco Zafra. Cereb Cortex 2005
Beatriz Cubelos, Cecilio Giménez, Francisco Zafra. Cereb Cortex 2005
20
Mechanism of chloride interaction with neurotransmitter:sodium symporters.
Elia Zomot, Annie Bendahan, Matthias Quick, Yongfang Zhao, Jonathan A Javitch, Baruch I Kanner. Nature 2007
Elia Zomot, Annie Bendahan, Matthias Quick, Yongfang Zhao, Jonathan A Javitch, Baruch I Kanner. Nature 2007
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.