A citation-based method for searching scientific literature

Vicky Lampropoulou, Alexey Sergushichev, Monika Bambouskova, Sharmila Nair, Emma E Vincent, Ekaterina Loginicheva, Luisa Cervantes-Barragan, Xiucui Ma, Stanley Ching-Cheng Huang, Takla Griss, Carla J Weinheimer, Shabaana Khader, Gwendalyn J Randolph, Edward J Pearce, Russell G Jones, Abhinav Diwan, Michael S Diamond, Maxim N Artyomov. Cell Metab 2016
Times Cited: 551







List of co-cited articles
981 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P Jedrychowski, Ana S H Costa, Maureen Higgins, Emily Hams,[...]. Nature 2018
586
55

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
G M Tannahill, A M Curtis, J Adamik, E M Palsson-McDermott, A F McGettrick, G Goel, C Frezza, N J Bernard, B Kelly, N H Foley,[...]. Nature 2013
42

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
Alessandro Michelucci, Thekla Cordes, Jenny Ghelfi, Arnaud Pailot, Norbert Reiling, Oliver Goldmann, Tina Binz, André Wegner, Aravind Tallam, Antonio Rausell,[...]. Proc Natl Acad Sci U S A 2013
487
41

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Evanna L Mills, Beth Kelly, Angela Logan, Ana S H Costa, Mukund Varma, Clare E Bryant, Panagiotis Tourlomousis, J Henry M Däbritz, Eyal Gottlieb, Isabel Latorre,[...]. Cell 2016
839
38

Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.
Monika Bambouskova, Laurent Gorvel, Vicky Lampropoulou, Alexey Sergushichev, Ekaterina Loginicheva, Kendall Johnson, Daniel Korenfeld, Mary Elizabeth Mathyer, Hyeryun Kim, Li-Hao Huang,[...]. Nature 2018
257
36

Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
Abhishek K Jha, Stanley Ching-Cheng Huang, Alexey Sergushichev, Vicky Lampropoulou, Yulia Ivanova, Ekaterina Loginicheva, Karina Chmielewski, Kelly M Stewart, Juliet Ashall, Bart Everts,[...]. Immunity 2015
889
35

Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels.
Thekla Cordes, Martina Wallace, Alessandro Michelucci, Ajit S Divakaruni, Sean C Sapcariu, Carole Sousa, Haruhiko Koseki, Pedro Cabrales, Anne N Murphy, Karsten Hiller,[...]. J Biol Chem 2016
222
32

α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming.
Pu-Ste Liu, Haiping Wang, Xiaoyun Li, Tung Chao, Tony Teav, Stefan Christen, Giusy Di Conza, Wan-Chen Cheng, Chih-Hung Chou, Magdalena Vavakova,[...]. Nat Immunol 2017
374
21

The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation.
Alexander Hooftman, Stefano Angiari, Svenja Hester, Sarah E Corcoran, Marah C Runtsch, Chris Ling, Melanie C Ruzek, Peter F Slivka, Anne F McGettrick, Kathy Banahan,[...]. Cell Metab 2020
84
25

Itaconate: the poster child of metabolic reprogramming in macrophage function.
Luke A J O'Neill, Maxim N Artyomov. Nat Rev Immunol 2019
152
20

4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects.
Shan-Ting Liao, Chao Han, Ding-Qiao Xu, Xiao-Wei Fu, Jun-Song Wang, Ling-Yi Kong. Nat Commun 2019
85
21

Comparative evaluation of itaconate and its derivatives reveals divergent inflammasome and type I interferon regulation in macrophages.
Amanda Swain, Monika Bambouskova, Hyeryun Kim, Prabhakar Sairam Andhey, Dustin Duncan, Karine Auclair, Victor Chubukov, Donald M Simons, Thomas P Roddy, Kelly M Stewart,[...]. Nat Metab 2020
60
30

Irg1 expression in myeloid cells prevents immunopathology during M. tuberculosis infection.
Sharmila Nair, Jeremy P Huynh, Vicky Lampropoulou, Ekaterina Loginicheva, Ekaterina Esaulova, Anshu P Gounder, Adrianus C M Boon, Elizabeth A Schwarzkopf, Tara R Bradstreet, Brian T Edelson,[...]. J Exp Med 2018
99
18

S-glycosylation-based cysteine profiling reveals regulation of glycolysis by itaconate.
Wei Qin, Ke Qin, Yanling Zhang, Wentong Jia, Ying Chen, Bo Cheng, Linghang Peng, Nan Chen, Yuan Liu, Wen Zhou,[...]. Nat Chem Biol 2019
75
22

The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons.
Brian P Daniels, Sigal B Kofman, Julian R Smith, Geoffrey T Norris, Annelise G Snyder, Joseph P Kolb, Xia Gao, Jason W Locasale, Jennifer Martinez, Michael Gale,[...]. Immunity 2019
105
15

Itaconic acid is a mammalian metabolite induced during macrophage activation.
Cheryl L Strelko, Wenyun Lu, Fay J Dufort, Thomas N Seyfried, Thomas C Chiles, Joshua D Rabinowitz, Mary F Roberts. J Am Chem Soc 2011
167
15

Immunometabolism governs dendritic cell and macrophage function.
Luke A J O'Neill, Edward J Pearce. J Exp Med 2016
779
15

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages.
Stanley Ching-Cheng Huang, Bart Everts, Yulia Ivanova, David O'Sullivan, Marcia Nascimento, Amber M Smith, Wandy Beatty, Latisha Love-Gregory, Wing Y Lam, Christina M O'Neill,[...]. Nat Immunol 2014
602
15

Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation.
Divya Vats, Lata Mukundan, Justin I Odegaard, Lina Zhang, Kristi L Smith, Christine R Morel, Roger A Wagner, David R Greaves, Peter J Murray, Ajay Chawla. Cell Metab 2006
849
15

Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury.
Thekla Cordes, Alfredo Lucas, Ajit S Divakaruni, Anne N Murphy, Pedro Cabrales, Christian M Metallo. Mol Metab 2020
43
34

Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages.
Eva M Palsson-McDermott, Anne M Curtis, Gautam Goel, Mario A R Lauterbach, Frederick J Sheedy, Laura E Gleeson, Mirjam W M van den Bosch, Susan R Quinn, Raquel Domingo-Fernandez, Daniel G W Johnston,[...]. Cell Metab 2015
544
15

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.
Rob J W Arts, Boris Novakovic, Rob Ter Horst, Agostinho Carvalho, Siroon Bekkering, Ekta Lachmandas, Fernando Rodrigues, Ricardo Silvestre, Shih-Chin Cheng, Shuang-Yin Wang,[...]. Cell Metab 2016
384
13

The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.
Jorge Domínguez-Andrés, Boris Novakovic, Yang Li, Brendon P Scicluna, Mark S Gresnigt, Rob J W Arts, Marije Oosting, Simone J C F M Moorlag, Laszlo A Groh, Jelle Zwaag,[...]. Cell Metab 2019
143
13

Krebs Cycle Reborn in Macrophage Immunometabolism.
Dylan G Ryan, Luke A J O'Neill. Annu Rev Immunol 2020
82
15

Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.
Mario A Lauterbach, Jasmin E Hanke, Magdalini Serefidou, Matthew S J Mangan, Carl-Christian Kolbe, Timo Hess, Maximilian Rothe, Romina Kaiser, Florian Hoss, Jan Gehlen,[...]. Immunity 2019
103
13

A guide to immunometabolism for immunologists.
Luke A J O'Neill, Rigel J Kishton, Jeff Rathmell. Nat Rev Immunol 2016
12

IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid.
Jan Naujoks, Christoph Tabeling, Brian D Dill, Christine Hoffmann, Andrew S Brown, Mareike Kunze, Stefan Kempa, Andrea Peter, Hans-Joachim Mollenkopf, Anca Dorhoi,[...]. PLoS Pathog 2016
137
12

Macrophage Immunometabolism: Where Are We (Going)?
Jan Van den Bossche, Luke A O'Neill, Deepthi Menon. Trends Immunol 2017
414
12

Itaconate controls the severity of pulmonary fibrosis.
Patricia P Ogger, Gesa J Albers, Richard J Hewitt, Brendan J O'Sullivan, Joseph E Powell, Emily Calamita, Poonam Ghai, Simone A Walker, Peter McErlean, Peter Saunders,[...]. Sci Immunol 2020
29
41

Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors.
Jonathan M Weiss, Luke C Davies, Megan Karwan, Lilia Ileva, Michelle K Ozaki, Robert Ys Cheng, Lisa A Ridnour, Christina M Annunziata, David A Wink, Daniel W McVicar. J Clin Invest 2018
91
13

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.
Shih-Chin Cheng, Jessica Quintin, Robert A Cramer, Kelly M Shepardson, Sadia Saeed, Vinod Kumar, Evangelos J Giamarellos-Bourboulis, Joost H A Martens, Nagesha Appukudige Rao, Ali Aghajanirefah,[...]. Science 2014
975
11

Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase.
Erika M Palmieri, Marieli Gonzalez-Cotto, Walter A Baseler, Luke C Davies, Bart Ghesquière, Nunziata Maio, Christopher M Rice, Tracey A Rouault, Teresa Cassel, Richard M Higashi,[...]. Nat Commun 2020
97
11

Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity.
Michael D Kornberg, Pavan Bhargava, Paul M Kim, Vasanta Putluri, Adele M Snowman, Nagireddy Putluri, Peter A Calabresi, Solomon H Snyder. Science 2018
274
11

Metabolic regulation of gene expression by histone lactylation.
Di Zhang, Zhanyun Tang, He Huang, Guolin Zhou, Chang Cui, Yejing Weng, Wenchao Liu, Sunjoo Kim, Sangkyu Lee, Mathew Perez-Neut,[...]. Nature 2019
448
11

Bacterial itaconate degradation promotes pathogenicity.
Jahminy Sasikaran, Michał Ziemski, Piotr K Zadora, Angela Fleig, Ivan A Berg. Nat Chem Biol 2014
101
11

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Edward T Chouchani, Victoria R Pell, Edoardo Gaude, Dunja Aksentijević, Stephanie Y Sundier, Ellen L Robb, Angela Logan, Sergiy M Nadtochiy, Emily N J Ord, Anthony C Smith,[...]. Nature 2014
11

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.
Jan Van den Bossche, Jeroen Baardman, Natasja A Otto, Saskia van der Velden, Annette E Neele, Susan M van den Berg, Rosario Luque-Martin, Hung-Jen Chen, Marieke C S Boshuizen, Mohamed Ahmed,[...]. Cell Rep 2016
343
11

Glycolytic Stimulation Is Not a Requirement for M2 Macrophage Differentiation.
Feilong Wang, Song Zhang, Ivan Vuckovic, Ryounghoon Jeon, Amir Lerman, Clifford D Folmes, Petras P Dzeja, Joerg Herrmann. Cell Metab 2018
118
11

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription.
Eri H Kobayashi, Takafumi Suzuki, Ryo Funayama, Takeshi Nagashima, Makiko Hayashi, Hiroki Sekine, Nobuyuki Tanaka, Takashi Moriguchi, Hozumi Motohashi, Keiko Nakayama,[...]. Nat Commun 2016
723
11


Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
Oscar R Colegio, Ngoc-Quynh Chu, Alison L Szabo, Thach Chu, Anne Marie Rhebergen, Vikram Jairam, Nika Cyrus, Carolyn E Brokowski, Stephanie C Eisenbarth, Gillian M Phillips,[...]. Nature 2014
10

Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression.
Johannes Meiser, Lisa Krämer, Sean C Sapcariu, Nadia Battello, Jenny Ghelfi, Aymeric Fouquier D'Herouel, Alexander Skupin, Karsten Hiller. J Biol Chem 2016
120
10

Macrophage activation and polarization: nomenclature and experimental guidelines.
Peter J Murray, Judith E Allen, Subhra K Biswas, Edward A Fisher, Derek W Gilroy, Sergij Goerdt, Siamon Gordon, John A Hamilton, Lionel B Ivashkiv, Toby Lawrence,[...]. Immunity 2014
10



TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.
Bart Everts, Eyal Amiel, Stanley Ching-Cheng Huang, Amber M Smith, Chih-Hao Chang, Wing Y Lam, Veronika Redmann, Tori C Freitas, Julianna Blagih, Gerritje J W van der Windt,[...]. Nat Immunol 2014
596
9

Triggering the succinate receptor GPR91 on dendritic cells enhances immunity.
Tina Rubic, Günther Lametschwandtner, Sandra Jost, Sonja Hinteregger, Julia Kund, Nicole Carballido-Perrig, Christoph Schwärzler, Tobias Junt, Hans Voshol, Josef G Meingassner,[...]. Nat Immunol 2008
272
9

The Immunomodulatory Potential of the Metabolite Itaconate.
Alexander Hooftman, Luke A J O'Neill. Trends Immunol 2019
60
15

Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation.
Sebastián A Riquelme, Kalle Liimatta, Tania Wong Fok Lung, Blanche Fields, Danielle Ahn, David Chen, Carmen Lozano, Yolanda Sáenz, Anne-Catrin Uhlemann, Barbara C Kahl,[...]. Cell Metab 2020
48
18

Coupling Krebs cycle metabolites to signalling in immunity and cancer.
Dylan G Ryan, Michael P Murphy, Christian Frezza, Hiran A Prag, Edward T Chouchani, Luke A O'Neill, Evanna L Mills. Nat Metab 2019
146
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.