A citation-based method for searching scientific literature

Brian J Altman, Zachary E Stine, Chi V Dang. Nat Rev Cancer 2016
Times Cited: 785







List of co-cited articles
672 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
21

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
20

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
17

Glutamine and cancer: cell biology, physiology, and clinical opportunities.
Christopher T Hensley, Ajla T Wasti, Ralph J DeBerardinis. J Clin Invest 2013
687
15

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
Jaekyoung Son, Costas A Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M Perera, Cristina R Ferrone, Edouard Mullarky, Ng Shyh-Chang,[...]. Nature 2013
14

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
14

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.
Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang, Yun-Sil Lee, Kayoko Kita, Takafumi Ochi, Karen I Zeller, Angelo M De Marzo, Jennifer E Van Eyk, Joshua T Mendell,[...]. Nature 2009
14

Glutamine addiction: a new therapeutic target in cancer.
David R Wise, Craig B Thompson. Trends Biochem Sci 2010
14

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
David R Wise, Ralph J DeBerardinis, Anthony Mancuso, Nabil Sayed, Xiao-Yong Zhang, Harla K Pfeiffer, Ilana Nissim, Evgueni Daikhin, Marc Yudkoff, Steven B McMahon,[...]. Proc Natl Acad Sci U S A 2008
13

On the origin of cancer cells.
O WARBURG. Science 1956
13

Glutamine Metabolism in Cancer: Understanding the Heterogeneity.
Ahmad A Cluntun, Michael J Lukey, Richard A Cerione, Jason W Locasale. Trends Cancer 2017
265
13

Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Matt I Gross, Susan D Demo, Jennifer B Dennison, Lijing Chen, Tania Chernov-Rogan, Bindu Goyal, Julie R Janes, Guy J Laidig, Evan R Lewis, Jim Li,[...]. Mol Cancer Ther 2014
546
12

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.
Michael L Schulte, Allie Fu, Ping Zhao, Jun Li, Ling Geng, Shannon T Smith, Jumpei Kondo, Robert J Coffey, Marc O Johnson, Jeffrey C Rathmell,[...]. Nat Med 2018
179
11

Glutamine reliance in cell metabolism.
Hee Chan Yoo, Ya Chun Yu, Yulseung Sung, Jung Min Han. Exp Mol Med 2020
85
11

Metabolic reprogramming and cancer progression.
Brandon Faubert, Ashley Solmonson, Ralph J DeBerardinis. Science 2020
368
10

Glutaminolysis: A Hallmark of Cancer Metabolism.
Lifeng Yang, Sriram Venneti, Deepak Nagrath. Annu Rev Biomed Eng 2017
259
10

Bidirectional transport of amino acids regulates mTOR and autophagy.
Paul Nicklin, Philip Bergman, Bailin Zhang, Ellen Triantafellow, Henry Wang, Beat Nyfeler, Haidi Yang, Marc Hild, Charles Kung, Christopher Wilson,[...]. Cell 2009
9

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells.
Anne Le, Andrew N Lane, Max Hamaker, Sminu Bose, Arvin Gouw, Joseph Barbi, Takashi Tsukamoto, Camilio J Rojas, Barbara S Slusher, Haixia Zhang,[...]. Cell Metab 2012
703
8

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.
Ralph J DeBerardinis, Julian J Lum, Georgia Hatzivassiliou, Craig B Thompson. Cell Metab 2008
8

Targeting mitochondrial glutaminase activity inhibits oncogenic transformation.
Jian-Bin Wang, Jon W Erickson, Reina Fuji, Sekar Ramachandran, Ping Gao, Ramani Dinavahi, Kristin F Wilson, Andre L B Ambrosio, Sandra M G Dias, Chi V Dang,[...]. Cancer Cell 2010
559
8

Cellular fatty acid metabolism and cancer.
Erin Currie, Almut Schulze, Rudolf Zechner, Tobias C Walther, Robert V Farese. Cell Metab 2013
8

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation.
Vinicius Cruzat, Marcelo Macedo Rogero, Kevin Noel Keane, Rui Curi, Philip Newsholme. Nutrients 2018
270
7

As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid.
Natalya N Pavlova, Sheng Hui, Jonathan M Ghergurovich, Jing Fan, Andrew M Intlekofer, Richard M White, Joshua D Rabinowitz, Craig B Thompson, Ji Zhang. Cell Metab 2018
134
7

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
Nathalie Jacque, Anne Marie Ronchetti, Clément Larrue, Godelieve Meunier, Rudy Birsen, Lise Willems, Estelle Saland, Justine Decroocq, Thiago Trovati Maciel, Mireille Lambert,[...]. Blood 2015
220
7


Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
7

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion.
Robert D Leone, Liang Zhao, Judson M Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L Arwood, Ian A Bettencourt, Chirag H Patel, Jiayu Wen,[...]. Science 2019
299
7

The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
7

Ferroptosis: an iron-dependent form of nonapoptotic cell death.
Scott J Dixon, Kathryn M Lemberg, Michael R Lamprecht, Rachid Skouta, Eleina M Zaitsev, Caroline E Gleason, Darpan N Patel, Andras J Bauer, Alexandra M Cantley, Wan Seok Yang,[...]. Cell 2012
7

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.
Lucas B Sullivan, Dan Y Gui, Aaron M Hosios, Lauren N Bush, Elizaveta Freinkman, Matthew G Vander Heiden. Cell 2015
573
7

α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming.
Pu-Ste Liu, Haiping Wang, Xiaoyun Li, Tung Chao, Tony Teav, Stefan Christen, Giusy Di Conza, Wan-Chen Cheng, Chih-Hung Chou, Magdalena Vavakova,[...]. Nat Immunol 2017
384
6

Reductive carboxylation supports growth in tumour cells with defective mitochondria.
Andrew R Mullen, William W Wheaton, Eunsook S Jin, Pei-Hsuan Chen, Lucas B Sullivan, Tzuling Cheng, Youfeng Yang, W Marston Linehan, Navdeep S Chandel, Ralph J DeBerardinis. Nature 2011
837
6

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
6

Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis.
Erika M Palmieri, Alessio Menga, Rosa Martín-Pérez, Annamaria Quinto, Carla Riera-Domingo, Giacoma De Tullio, Douglas C Hooper, Wouter H Lamers, Bart Ghesquière, Daniel W McVicar,[...]. Cell Rep 2017
151
6

ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation.
Guoliang Qing, Bo Li, Annette Vu, Nicolas Skuli, Zandra E Walton, Xueyuan Liu, Patrick A Mayes, David R Wise, Craig B Thompson, John M Maris,[...]. Cancer Cell 2012
229
6

Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion.
Ji Zhang, Jing Fan, Sriram Venneti, Justin R Cross, Toshimitsu Takagi, Bhavneet Bhinder, Hakim Djaballah, Masayuki Kanai, Emily H Cheng, Alexander R Judkins,[...]. Mol Cell 2014
225
6

The multifaceted roles of fatty acid synthesis in cancer.
Florian Röhrig, Almut Schulze. Nat Rev Cancer 2016
572
6

Glutaminolysis as a target for cancer therapy.
L Jin, G N Alesi, S Kang. Oncogene 2016
208
6

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.
Kıvanç Birsoy, Tim Wang, Walter W Chen, Elizaveta Freinkman, Monther Abu-Remaileh, David M Sabatini. Cell 2015
653
6

Cancer cell metabolism: the essential role of the nonessential amino acid, glutamine.
Ji Zhang, Natalya N Pavlova, Craig B Thompson. EMBO J 2017
258
6

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism.
Douglas E Biancur, Joao A Paulo, Beata Małachowska, Maria Quiles Del Rey, Cristovão M Sousa, Xiaoxu Wang, Albert S W Sohn, Gerald C Chu, Steven P Gygi, J Wade Harper,[...]. Nat Commun 2017
144
6

Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES).
Mary M Robinson, Steven J McBryant, Takashi Tsukamoto, Camilo Rojas, Dana V Ferraris, Sean K Hamilton, Jeffrey C Hansen, Norman P Curthoys. Biochem J 2007
218
6

Metabolic regulation of cell growth and proliferation.
Jiajun Zhu, Craig B Thompson. Nat Rev Mol Cell Biol 2019
251
6

The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.
Alfred Csibi, Sarah-Maria Fendt, Chenggang Li, George Poulogiannis, Andrew Y Choo, Douglas J Chapski, Seung Min Jeong, Jamie M Dempsey, Andrey Parkhitko, Tasha Morrison,[...]. Cell 2013
363
5

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth.
Lifeng Yang, Abhinav Achreja, Tsz-Lun Yeung, Lingegowda S Mangala, Dahai Jiang, Cecil Han, Joelle Baddour, Juan C Marini, Joseph Ni, Ryuichi Nakahara,[...]. Cell Metab 2016
190
5

Regulation of cancer cell metabolism.
Rob A Cairns, Isaac S Harris, Tak W Mak. Nat Rev Cancer 2011
5

Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation.
Alex J Bott, I-Chen Peng, Yongjun Fan, Brandon Faubert, Lu Zhao, Jinyu Li, Sarah Neidler, Yu Sun, Nadia Jaber, Dawid Krokowski,[...]. Cell Metab 2015
124
5

In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of 18F-(2S,4R)-4-Fluoroglutamine.
Mark P S Dunphy, James J Harding, Sriram Venneti, Hanwen Zhang, Eva M Burnazi, Jacqueline Bromberg, Antonio M Omuro, James J Hsieh, Ingo K Mellinghoff, Kevin Staton,[...]. Radiology 2018
51
9

Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo.
Sriram Venneti, Mark P Dunphy, Hanwen Zhang, Kenneth L Pitter, Patrick Zanzonico, Carl Campos, Sean D Carlin, Gaspare La Rocca, Serge Lyashchenko, Karl Ploessl,[...]. Sci Transl Med 2015
192
5

Metabolic regulation of gene expression by histone lactylation.
Di Zhang, Zhanyun Tang, He Huang, Guolin Zhou, Chang Cui, Yejing Weng, Wenchao Liu, Sunjoo Kim, Sangkyu Lee, Mathew Perez-Neut,[...]. Nature 2019
473
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.