Jasmine P Brown, Diana Hall, Christopher L Frank, Kathleen Wallace, William R Mundy, Timothy J Shafer. Toxicol Sci 2016
Times Cited: 28
Times Cited: 28
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From the Cover: Developmental Neurotoxicants Disrupt Activity in Cortical Networks on Microelectrode Arrays: Results of Screening 86 Compounds During Neural Network Formation.
Christopher L Frank, Jasmine P Brown, Kathleen Wallace, William R Mundy, Timothy J Shafer. Toxicol Sci 2017
Christopher L Frank, Jasmine P Brown, Kathleen Wallace, William R Mundy, Timothy J Shafer. Toxicol Sci 2017
60
Multi-well microelectrode array recordings detect neuroactivity of ToxCast compounds.
Pablo Valdivia, Matt Martin, William R LeFew, James Ross, Keith A Houck, Timothy J Shafer. Neurotoxicology 2014
Pablo Valdivia, Matt Martin, William R LeFew, James Ross, Keith A Houck, Timothy J Shafer. Neurotoxicology 2014
46
Expanding the test set: Chemicals with potential to disrupt mammalian brain development.
William R Mundy, Stephanie Padilla, Joseph M Breier, Kevin M Crofton, Mary E Gilbert, David W Herr, Karl F Jensen, Nicholas M Radio, Kathleen C Raffaele, Kelly Schumacher,[...]. Neurotoxicol Teratol 2015
William R Mundy, Stephanie Padilla, Joseph M Breier, Kevin M Crofton, Mary E Gilbert, David W Herr, Karl F Jensen, Nicholas M Radio, Kathleen C Raffaele, Kelly Schumacher,[...]. Neurotoxicol Teratol 2015
46
In vitro assessment of developmental neurotoxicity: use of microelectrode arrays to measure functional changes in neuronal network ontogeny.
Brian L Robinette, Joshua A Harrill, William R Mundy, Timothy J Shafer. Front Neuroeng 2011
Brian L Robinette, Joshua A Harrill, William R Mundy, Timothy J Shafer. Front Neuroeng 2011
46
Characterization of Early Cortical Neural Network Development in Multiwell Microelectrode Array Plates.
Ellese Cotterill, Diana Hall, Kathleen Wallace, William R Mundy, Stephen J Eglen, Timothy J Shafer. J Biomol Screen 2016
Ellese Cotterill, Diana Hall, Kathleen Wallace, William R Mundy, Stephen J Eglen, Timothy J Shafer. J Biomol Screen 2016
46
Microelectrode arrays: a physiologically based neurotoxicity testing platform for the 21st century.
Andrew F M Johnstone, Guenter W Gross, Dieter G Weiss, Olaf H-U Schroeder, Alexandra Gramowski, Timothy J Shafer. Neurotoxicology 2010
Andrew F M Johnstone, Guenter W Gross, Dieter G Weiss, Olaf H-U Schroeder, Alexandra Gramowski, Timothy J Shafer. Neurotoxicology 2010
42
Use of high content image analysis to detect chemical-induced changes in synaptogenesis in vitro.
Joshua A Harrill, Brian L Robinette, William R Mundy. Toxicol In Vitro 2011
Joshua A Harrill, Brian L Robinette, William R Mundy. Toxicol In Vitro 2011
42
Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity.
Anna Bal-Price, Helena T Hogberg, Kevin M Crofton, Mardas Daneshian, Rex E FitzGerald, Ellen Fritsche, Tuula Heinonen, Susanne Hougaard Bennekou, Stefanie Klima, Aldert H Piersma,[...]. ALTEX 2018
Anna Bal-Price, Helena T Hogberg, Kevin M Crofton, Mardas Daneshian, Rex E FitzGerald, Ellen Fritsche, Tuula Heinonen, Susanne Hougaard Bennekou, Stefanie Klima, Aldert H Piersma,[...]. ALTEX 2018
42
Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set.
Emma R McConnell, Maxine A McClain, James Ross, William R Lefew, Timothy J Shafer. Neurotoxicology 2012
Emma R McConnell, Maxine A McClain, James Ross, William R Lefew, Timothy J Shafer. Neurotoxicology 2012
39
Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals.
Kevin M Crofton, William R Mundy, Pamela J Lein, Anna Bal-Price, Sandra Coecke, Andrea E M Seiler, Holger Knaut, Leonora Buzanska, Alan Goldberg. ALTEX 2011
Kevin M Crofton, William R Mundy, Pamela J Lein, Anna Bal-Price, Sandra Coecke, Andrea E M Seiler, Holger Knaut, Leonora Buzanska, Alan Goldberg. ALTEX 2011
35
Burst and principal components analyses of MEA data for 16 chemicals describe at least three effects classes.
Cina M Mack, Bryant J Lin, James D Turner, Andrew F M Johnstone, Lyle D Burgoon, Timothy J Shafer. Neurotoxicology 2014
Cina M Mack, Bryant J Lin, James D Turner, Andrew F M Johnstone, Lyle D Burgoon, Timothy J Shafer. Neurotoxicology 2014
35
A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing.
Andrea Vassallo, Michela Chiappalone, Ricardo De Camargos Lopes, Bibiana Scelfo, Antonio Novellino, Enrico Defranchi, Taina Palosaari, Timo Weisschu, Tzutzuy Ramirez, Sergio Martinoia,[...]. Neurotoxicology 2017
Andrea Vassallo, Michela Chiappalone, Ricardo De Camargos Lopes, Bibiana Scelfo, Antonio Novellino, Enrico Defranchi, Taina Palosaari, Timo Weisschu, Tzutzuy Ramirez, Sergio Martinoia,[...]. Neurotoxicology 2017
35
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.
Anna Bal-Price, Kevin M Crofton, Marcel Leist, Sandra Allen, Michael Arand, Timo Buetler, Nathalie Delrue, Rex E FitzGerald, Thomas Hartung, Tuula Heinonen,[...]. Arch Toxicol 2015
Anna Bal-Price, Kevin M Crofton, Marcel Leist, Sandra Allen, Michael Arand, Timo Buetler, Nathalie Delrue, Rex E FitzGerald, Thomas Hartung, Tuula Heinonen,[...]. Arch Toxicol 2015
32
Developmental neurotoxicity guideline study: issues with methodology, evaluation and regulation.
Ryozo Tsuji, Kevin M Crofton. Congenit Anom (Kyoto) 2012
Ryozo Tsuji, Kevin M Crofton. Congenit Anom (Kyoto) 2012
32
Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities.
Lena Smirnova, Helena T Hogberg, Marcel Leist, Thomas Hartung. ALTEX 2014
Lena Smirnova, Helena T Hogberg, Marcel Leist, Thomas Hartung. ALTEX 2014
32
32
Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.
Michael Aschner, Sandra Ceccatelli, Mardas Daneshian, Ellen Fritsche, Nina Hasiwa, Thomas Hartung, Helena T Hogberg, Marcel Leist, Abby Li, William R Mundi,[...]. ALTEX 2017
Michael Aschner, Sandra Ceccatelli, Mardas Daneshian, Ellen Fritsche, Nina Hasiwa, Thomas Hartung, Helena T Hogberg, Marcel Leist, Abby Li, William R Mundi,[...]. ALTEX 2017
32
Testing for developmental neurotoxicity using a battery of in vitro assays for key cellular events in neurodevelopment.
Joshua A Harrill, Theresa Freudenrich, Kathleen Wallace, Kenneth Ball, Timothy J Shafer, William R Mundy. Toxicol Appl Pharmacol 2018
Joshua A Harrill, Theresa Freudenrich, Kathleen Wallace, Kenneth Ball, Timothy J Shafer, William R Mundy. Toxicol Appl Pharmacol 2018
32
Comparative human and rat neurospheres reveal species differences in chemical effects on neurodevelopmental key events.
Jenny Baumann, Kathrin Gassmann, Stefan Masjosthusmann, Denise DeBoer, Farina Bendt, Susanne Giersiefer, Ellen Fritsche. Arch Toxicol 2016
Jenny Baumann, Kathrin Gassmann, Stefan Masjosthusmann, Denise DeBoer, Farina Bendt, Susanne Giersiefer, Ellen Fritsche. Arch Toxicol 2016
28
Chronic 14-day exposure to insecticides or methylmercury modulates neuronal activity in primary rat cortical cultures.
Milou M L Dingemans, Marijke G Schütte, Daphne M M Wiersma, Aart de Groot, Regina G D M van Kleef, Fiona M J Wijnolts, Remco H S Westerink. Neurotoxicology 2016
Milou M L Dingemans, Marijke G Schütte, Daphne M M Wiersma, Aart de Groot, Regina G D M van Kleef, Fiona M J Wijnolts, Remco H S Westerink. Neurotoxicology 2016
33
OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes.
Ellen Fritsche, Kevin M Crofton, Antonio F Hernandez, Susanne Hougaard Bennekou, Marcel Leist, Anna Bal-Price, Elissa Reaves, Martin F Wilks, Andrea Terron, Roland Solecki,[...]. ALTEX 2017
Ellen Fritsche, Kevin M Crofton, Antonio F Hernandez, Susanne Hougaard Bennekou, Marcel Leist, Anna Bal-Price, Elissa Reaves, Martin F Wilks, Andrea Terron, Roland Solecki,[...]. ALTEX 2017
28
Application of micro-electrode arrays (MEAs) as an emerging technology for developmental neurotoxicity: evaluation of domoic acid-induced effects in primary cultures of rat cortical neurons.
Helena T Hogberg, Tomasz Sobanski, Antonio Novellino, Maurice Whelan, Dieter G Weiss, Anna K Bal-Price. Neurotoxicology 2011
Helena T Hogberg, Tomasz Sobanski, Antonio Novellino, Maurice Whelan, Dieter G Weiss, Anna K Bal-Price. Neurotoxicology 2011
28
Developmental neurotoxicity testing: a path forward.
Kevin M Crofton, William R Mundy, Timothy J Shafer. Congenit Anom (Kyoto) 2012
Kevin M Crofton, William R Mundy, Timothy J Shafer. Congenit Anom (Kyoto) 2012
28
Screening the ToxCast phase II libraries for alterations in network function using cortical neurons grown on multi-well microelectrode array (mwMEA) plates.
Jenna D Strickland, Matthew T Martin, Ann M Richard, Keith A Houck, Timothy J Shafer. Arch Toxicol 2018
Jenna D Strickland, Matthew T Martin, Ann M Richard, Keith A Houck, Timothy J Shafer. Arch Toxicol 2018
28
Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?
Anke M Tukker, Martje W G D M de Groot, Fiona M J Wijnolts, Emma E J Kasteel, Laura Hondebrink, Remco H S Westerink. ALTEX 2016
Anke M Tukker, Martje W G D M de Groot, Fiona M J Wijnolts, Emma E J Kasteel, Laura Hondebrink, Remco H S Westerink. ALTEX 2016
28
Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity.
Kristen R Ryan, Oksana Sirenko, Fred Parham, Jui-Hua Hsieh, Evan F Cromwell, Raymond R Tice, Mamta Behl. Neurotoxicology 2016
Kristen R Ryan, Oksana Sirenko, Fred Parham, Jui-Hua Hsieh, Evan F Cromwell, Raymond R Tice, Mamta Behl. Neurotoxicology 2016
28
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes.
Ellen Fritsche, Philippe Grandjean, Kevin M Crofton, Michael Aschner, Alan Goldberg, Tuula Heinonen, Ellen V S Hessel, Helena T Hogberg, Susanne Hougaard Bennekou, Pamela J Lein,[...]. Toxicol Appl Pharmacol 2018
Ellen Fritsche, Philippe Grandjean, Kevin M Crofton, Michael Aschner, Alan Goldberg, Tuula Heinonen, Ellen V S Hessel, Helena T Hogberg, Susanne Hougaard Bennekou, Pamela J Lein,[...]. Toxicol Appl Pharmacol 2018
28
Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures.
Nina V Stiegler, Anne K Krug, Florian Matt, Marcel Leist. Toxicol Sci 2011
Nina V Stiegler, Anne K Krug, Florian Matt, Marcel Leist. Toxicol Sci 2011
25
Neurotoxicity screening of (illicit) drugs using novel methods for analysis of microelectrode array (MEA) recordings.
L Hondebrink, A H A Verboven, W S Drega, S Schmeink, M W G D M de Groot, R G D M van Kleef, F M J Wijnolts, A de Groot, J Meulenbelt, R H S Westerink. Neurotoxicology 2016
L Hondebrink, A H A Verboven, W S Drega, S Schmeink, M W G D M de Groot, R G D M van Kleef, F M J Wijnolts, A de Groot, J Meulenbelt, R H S Westerink. Neurotoxicology 2016
25
An extremely rich repertoire of bursting patterns during the development of cortical cultures.
Daniel A Wagenaar, Jerome Pine, Steve M Potter. BMC Neurosci 2006
Daniel A Wagenaar, Jerome Pine, Steve M Potter. BMC Neurosci 2006
25
In vitro developmental neurotoxicity (DNT) testing: relevant models and endpoints.
Anna K Bal-Price, Helena T Hogberg, Leonora Buzanska, Petros Lenas, Erwin van Vliet, Thomas Hartung. Neurotoxicology 2010
Anna K Bal-Price, Helena T Hogberg, Leonora Buzanska, Petros Lenas, Erwin van Vliet, Thomas Hartung. Neurotoxicology 2010
25
Quantitative assessment of neurite outgrowth in human embryonic stem cell-derived hN2 cells using automated high-content image analysis.
Joshua A Harrill, Theresa M Freudenrich, Dave W Machacek, Steven L Stice, William R Mundy. Neurotoxicology 2010
Joshua A Harrill, Theresa M Freudenrich, Dave W Machacek, Steven L Stice, William R Mundy. Neurotoxicology 2010
25
Neurobehavioural effects of developmental toxicity.
Philippe Grandjean, Philip J Landrigan. Lancet Neurol 2014
Philippe Grandjean, Philip J Landrigan. Lancet Neurol 2014
25
Omnisphero: a high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro.
Martin R Schmuck, Thomas Temme, Katharina Dach, Denise de Boer, Marta Barenys, Farina Bendt, Axel Mosig, Ellen Fritsche. Arch Toxicol 2017
Martin R Schmuck, Thomas Temme, Katharina Dach, Denise de Boer, Marta Barenys, Farina Bendt, Axel Mosig, Ellen Fritsche. Arch Toxicol 2017
25
Defining toxicological tipping points in neuronal network development.
Christopher L Frank, Jasmine P Brown, Kathleen Wallace, John F Wambaugh, Imran Shah, Timothy J Shafer. Toxicol Appl Pharmacol 2018
Christopher L Frank, Jasmine P Brown, Kathleen Wallace, John F Wambaugh, Imran Shah, Timothy J Shafer. Toxicol Appl Pharmacol 2018
46
Evaluation of a human neurite growth assay as specific screen for developmental neurotoxicants.
Anne K Krug, Nina V Balmer, Florian Matt, Felix Schönenberger, Dorit Merhof, Marcel Leist. Arch Toxicol 2013
Anne K Krug, Nina V Balmer, Florian Matt, Felix Schönenberger, Dorit Merhof, Marcel Leist. Arch Toxicol 2013
21
Putative adverse outcome pathways relevant to neurotoxicity.
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J Lein, Jochem Louisse,[...]. Crit Rev Toxicol 2015
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J Lein, Jochem Louisse,[...]. Crit Rev Toxicol 2015
21
A multiplexed assay for determination of neurotoxicant effects on spontaneous network activity and viability from microelectrode arrays.
Kathleen Wallace, Jenna D Strickland, Pablo Valdivia, William R Mundy, Timothy J Shafer. Neurotoxicology 2015
Kathleen Wallace, Jenna D Strickland, Pablo Valdivia, William R Mundy, Timothy J Shafer. Neurotoxicology 2015
21
Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals.
A Novellino, Bibiana Scelfo, T Palosaari, A Price, Tomasz Sobanski, T J Shafer, A F M Johnstone, G W Gross, A Gramowski, O Schroeder,[...]. Front Neuroeng 2011
A Novellino, Bibiana Scelfo, T Palosaari, A Price, Tomasz Sobanski, T J Shafer, A F M Johnstone, G W Gross, A Gramowski, O Schroeder,[...]. Front Neuroeng 2011
21
ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology.
Ann M Richard, Richard S Judson, Keith A Houck, Christopher M Grulke, Patra Volarath, Inthirany Thillainadarajah, Chihae Yang, James Rathman, Matthew T Martin, John F Wambaugh,[...]. Chem Res Toxicol 2016
Ann M Richard, Richard S Judson, Keith A Houck, Christopher M Grulke, Patra Volarath, Inthirany Thillainadarajah, Chihae Yang, James Rathman, Matthew T Martin, John F Wambaugh,[...]. Chem Res Toxicol 2016
21
Detection of marine neurotoxins in food safety testing using a multielectrode array.
Jonathan Nicolas, Peter J M Hendriksen, Regina G D M van Kleef, Aart de Groot, Toine F H Bovee, Ivonne M C M Rietjens, Remco H S Westerink. Mol Nutr Food Res 2014
Jonathan Nicolas, Peter J M Hendriksen, Regina G D M van Kleef, Aart de Groot, Toine F H Bovee, Ivonne M C M Rietjens, Remco H S Westerink. Mol Nutr Food Res 2014
21
Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies.
Sandra Coecke, Alan M Goldberg, Sandra Allen, Leonora Buzanska, Gemma Calamandrei, Kevin Crofton, Lars Hareng, Thomas Hartung, Holger Knaut, Paul Honegger,[...]. Environ Health Perspect 2007
Sandra Coecke, Alan M Goldberg, Sandra Allen, Leonora Buzanska, Gemma Calamandrei, Kevin Crofton, Lars Hareng, Thomas Hartung, Holger Knaut, Paul Honegger,[...]. Environ Health Perspect 2007
21
Evaluation of Chemical Effects on Network Formation in Cortical Neurons Grown on Microelectrode Arrays.
Timothy J Shafer, Jasmine P Brown, Brittany Lynch, Sylmarie Davila-Montero, Kathleen Wallace, Katie Paul Friedman. Toxicol Sci 2019
Timothy J Shafer, Jasmine P Brown, Brittany Lynch, Sylmarie Davila-Montero, Kathleen Wallace, Katie Paul Friedman. Toxicol Sci 2019
54
Comparative sensitivity of human and rat neural cultures to chemical-induced inhibition of neurite outgrowth.
Joshua A Harrill, Theresa M Freudenrich, Brian L Robinette, William R Mundy. Toxicol Appl Pharmacol 2011
Joshua A Harrill, Theresa M Freudenrich, Brian L Robinette, William R Mundy. Toxicol Appl Pharmacol 2011
17
Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation.
Anna K Bal-Price, Sandra Coecke, Lucio Costa, Kevin M Crofton, Ellen Fritsche, Alan Goldberg, Philippe Grandjean, Pamela J Lein, Abby Li, Roberto Lucchini,[...]. ALTEX 2012
Anna K Bal-Price, Sandra Coecke, Lucio Costa, Kevin M Crofton, Ellen Fritsche, Alan Goldberg, Philippe Grandjean, Pamela J Lein, Abby Li, Roberto Lucchini,[...]. ALTEX 2012
17
Meeting report: alternatives for developmental neurotoxicity testing.
Pamela Lein, Paul Locke, Alan Goldberg. Environ Health Perspect 2007
Pamela Lein, Paul Locke, Alan Goldberg. Environ Health Perspect 2007
17
Use of high content image analyses to detect chemical-mediated effects on neurite sub-populations in primary rat cortical neurons.
Joshua A Harrill, Brian L Robinette, Theresa Freudenrich, William R Mundy. Neurotoxicology 2013
Joshua A Harrill, Brian L Robinette, Theresa Freudenrich, William R Mundy. Neurotoxicology 2013
17
Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment.
Gerald T Ankley, Richard S Bennett, Russell J Erickson, Dale J Hoff, Michael W Hornung, Rodney D Johnson, David R Mount, John W Nichols, Christine L Russom, Patricia K Schmieder,[...]. Environ Toxicol Chem 2010
Gerald T Ankley, Richard S Bennett, Russell J Erickson, Dale J Hoff, Michael W Hornung, Rodney D Johnson, David R Mount, John W Nichols, Christine L Russom, Patricia K Schmieder,[...]. Environ Toxicol Chem 2010
17
The toxicity data landscape for environmental chemicals.
Richard Judson, Ann Richard, David J Dix, Keith Houck, Matthew Martin, Robert Kavlock, Vicki Dellarco, Tala Henry, Todd Holderman, Philip Sayre,[...]. Environ Health Perspect 2009
Richard Judson, Ann Richard, David J Dix, Keith Houck, Matthew Martin, Robert Kavlock, Vicki Dellarco, Tala Henry, Todd Holderman, Philip Sayre,[...]. Environ Health Perspect 2009
17
Quantitative differences in developmental profiles of spontaneous activity in cortical and hippocampal cultures.
Paul Charlesworth, Ellese Cotterill, Andrew Morton, Seth G N Grant, Stephen J Eglen. Neural Dev 2015
Paul Charlesworth, Ellese Cotterill, Andrew Morton, Seth G N Grant, Stephen J Eglen. Neural Dev 2015
17
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.