A citation-based method for searching scientific literature

Cristovão M Sousa, Douglas E Biancur, Xiaoxu Wang, Christopher J Halbrook, Mara H Sherman, Li Zhang, Daniel Kremer, Rosa F Hwang, Agnes K Witkiewicz, Haoqiang Ying, John M Asara, Ronald M Evans, Lewis C Cantley, Costas A Lyssiotis, Alec C Kimmelman. Nature 2016
Times Cited: 558







List of co-cited articles
1397 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
Jaekyoung Son, Costas A Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M Perera, Cristina R Ferrone, Edouard Mullarky, Ng Shyh-Chang,[...]. Nature 2013
24

Pancreatic cancers require autophagy for tumor growth.
Shenghong Yang, Xiaoxu Wang, Gianmarco Contino, Marc Liesa, Ergun Sahin, Haoqiang Ying, Alexandra Bause, Yinghua Li, Jayne M Stommel, Giacomo Dell'antonio,[...]. Genes Dev 2011
957
22

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
Cosimo Commisso, Shawn M Davidson, Rengin G Soydaner-Azeloglu, Seth J Parker, Jurre J Kamphorst, Sean Hackett, Elda Grabocka, Michel Nofal, Jeffrey A Drebin, Craig B Thompson,[...]. Nature 2013
929
20

Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein.
Jurre J Kamphorst, Michel Nofal, Cosimo Commisso, Sean R Hackett, Wenyun Lu, Elda Grabocka, Matthew G Vander Heiden, George Miller, Jeffrey A Drebin, Dafna Bar-Sagi,[...]. Cancer Res 2015
438
20

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.
Daniel Öhlund, Abram Handly-Santana, Giulia Biffi, Ela Elyada, Ana S Almeida, Mariano Ponz-Sarvise, Vincenzo Corbo, Tobiloba E Oni, Stephen A Hearn, Eun Jung Lee,[...]. J Exp Med 2017
880
18

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.
Andrew D Rhim, Paul E Oberstein, Dafydd H Thomas, Emily T Mirek, Carmine F Palermo, Stephen A Sastra, Erin N Dekleva, Tyler Saunders, Claudia P Becerra, Ian W Tattersall,[...]. Cancer Cell 2014
18

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
Keisuke Yamamoto, Anthony Venida, Julian Yano, Douglas E Biancur, Miwako Kakiuchi, Suprit Gupta, Albert S W Sohn, Subhadip Mukhopadhyay, Elaine Y Lin, Seth J Parker,[...]. Nature 2020
287
18

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Haoqiang Ying, Alec C Kimmelman, Costas A Lyssiotis, Sujun Hua, Gerald C Chu, Eliot Fletcher-Sananikone, Jason W Locasale, Jaekyoung Son, Hailei Zhang, Jonathan L Coloff,[...]. Cell 2012
18

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
18

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.
Kenneth P Olive, Michael A Jacobetz, Christian J Davidson, Aarthi Gopinathan, Dominick McIntyre, Davina Honess, Basetti Madhu, Mae A Goldgraben, Meredith E Caldwell, David Allard,[...]. Science 2009
17

Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms.
Annan Yang, Grit Herter-Sprie, Haikuo Zhang, Elaine Y Lin, Douglas Biancur, Xiaoxu Wang, Jiehui Deng, Josephine Hai, Shenghong Yang, Kwok-Kin Wong,[...]. Cancer Discov 2018
166
17

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
16

A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression.
Francesca R Auciello, Vinay Bulusu, Chet Oon, Jacqueline Tait-Mulder, Mark Berry, Sohinee Bhattacharyya, Sergey Tumanov, Brittany L Allen-Petersen, Jason Link, Nicholas D Kendsersky,[...]. Cancer Discov 2019
102
15

Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations.
Annan Yang, N V Rajeshkumar, Xiaoxu Wang, Shinichi Yabuuchi, Brian M Alexander, Gerald C Chu, Daniel D Von Hoff, Anirban Maitra, Alec C Kimmelman. Cancer Discov 2014
304
15

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma.
Paolo P Provenzano, Carlos Cuevas, Amy E Chang, Vikas K Goel, Daniel D Von Hoff, Sunil R Hingorani. Cancer Cell 2012
14

A framework for advancing our understanding of cancer-associated fibroblasts.
Erik Sahai, Igor Astsaturov, Edna Cukierman, David G DeNardo, Mikala Egeblad, Ronald M Evans, Douglas Fearon, Florian R Greten, Sunil R Hingorani, Tony Hunter,[...]. Nat Rev Cancer 2020
817
14

Selective Alanine Transporter Utilization Creates a Targetable Metabolic Niche in Pancreatic Cancer.
Seth J Parker, Caroline R Amendola, Kate E R Hollinshead, Qijia Yu, Keisuke Yamamoto, Joel Encarnación-Rosado, Rebecca E Rose, Madeleine M LaRue, Albert S W Sohn, Doug E Biancur,[...]. Cancer Discov 2020
43
32

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts.
Ela Elyada, Mohan Bolisetty, Pasquale Laise, William F Flynn, Elise T Courtois, Richard A Burkhart, Jonathan A Teinor, Pascal Belleau, Giulia Biffi, Matthew S Lucito,[...]. Cancer Discov 2019
466
13

Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism.
Hongyun Zhao, Lifeng Yang, Joelle Baddour, Abhinav Achreja, Vincent Bernard, Tyler Moss, Juan C Marini, Thavisha Tudawe, Elena G Seviour, F Anthony San Lucas,[...]. Elife 2016
484
13

Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions.
Orianne Olivares, Jared R Mayers, Victoire Gouirand, Margaret E Torrence, Tristan Gicquel, Laurence Borge, Sophie Lac, Julie Roques, Marie-Noëlle Lavaut, Patrice Berthezène,[...]. Nat Commun 2017
172
13

Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.
Berna C Özdemir, Tsvetelina Pentcheva-Hoang, Julienne L Carstens, Xiaofeng Zheng, Chia-Chin Wu, Tyler R Simpson, Hanane Laklai, Hikaru Sugimoto, Christoph Kahlert, Sergey V Novitskiy,[...]. Cancer Cell 2014
13

Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
Rushika M Perera, Svetlana Stoykova, Brandon N Nicolay, Kenneth N Ross, Julien Fitamant, Myriam Boukhali, Justine Lengrand, Vikram Deshpande, Martin K Selig, Cristina R Ferrone,[...]. Nature 2015
471
13

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth.
Lifeng Yang, Abhinav Achreja, Tsz-Lun Yeung, Lingegowda S Mangala, Dahai Jiang, Cecil Han, Joelle Baddour, Juan C Marini, Joseph Ni, Ryuichi Nakahara,[...]. Cell Metab 2016
190
13

Autophagy Is Required for Activation of Pancreatic Stellate Cells, Associated With Pancreatic Cancer Progression and Promotes Growth of Pancreatic Tumors in Mice.
Sho Endo, Kohei Nakata, Kenoki Ohuchida, Shin Takesue, Hiromichi Nakayama, Toshiya Abe, Kazuhiro Koikawa, Takashi Okumura, Masafumi Sada, Kohei Horioka,[...]. Gastroenterology 2017
122
13

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
13

The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma.
Stephanos Pavlides, Diana Whitaker-Menezes, Remedios Castello-Cros, Neal Flomenberg, Agnieszka K Witkiewicz, Philippe G Frank, Mathew C Casimiro, Chenguang Wang, Paolo Fortina, Sankar Addya,[...]. Cell Cycle 2009
827
12

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers.
Conan G Kinsey, Soledad A Camolotto, Amelie M Boespflug, Katrin P Guillen, Mona Foth, Amanda Truong, Sophia S Schuman, Jill E Shea, Michael T Seipp, Jeffrey T Yap,[...]. Nat Med 2019
287
12

Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability.
Mark R Sullivan, Laura V Danai, Caroline A Lewis, Sze Ham Chan, Dan Y Gui, Tenzin Kunchok, Emily A Dennstedt, Matthew G Vander Heiden, Alexander Muir. Elife 2019
167
12

Lactate Metabolism in Human Lung Tumors.
Brandon Faubert, Kevin Y Li, Ling Cai, Christopher T Hensley, Jiyeon Kim, Lauren G Zacharias, Chendong Yang, Quyen N Do, Sarah Doucette, Daniel Burguete,[...]. Cell 2017
548
12

IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma.
Giulia Biffi, Tobiloba E Oni, Benjamin Spielman, Yuan Hao, Ela Elyada, Youngkyu Park, Jonathan Preall, David A Tuveson. Cancer Discov 2019
392
11

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.
Mara H Sherman, Ruth T Yu, Dannielle D Engle, Ning Ding, Annette R Atkins, Herve Tiriac, Eric A Collisson, Frances Connor, Terry Van Dyke, Serguei Kozlov,[...]. Cell 2014
618
11

Effect of Gemcitabine and nab-Paclitaxel With or Without Hydroxychloroquine on Patients With Advanced Pancreatic Cancer: A Phase 2 Randomized Clinical Trial.
Thomas B Karasic, Mark H O'Hara, Arturo Loaiza-Bonilla, Kim A Reiss, Ursina R Teitelbaum, Erkut Borazanci, Ana De Jesus-Acosta, Colleen Redlinger, Jessica A Burrell, Daniel A Laheru,[...]. JAMA Oncol 2019
123
11

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.
Andrea Viale, Piergiorgio Pettazzoni, Costas A Lyssiotis, Haoqiang Ying, Nora Sánchez, Matteo Marchesini, Alessandro Carugo, Tessa Green, Sahil Seth, Virginia Giuliani,[...]. Nature 2014
724
11

Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells.
Jessie Yanxiang Guo, Xin Teng, Saurabh V Laddha, Sirui Ma, Stephen C Van Nostrand, Yang Yang, Sinan Khor, Chang S Chan, Joshua D Rabinowitz, Eileen White. Genes Dev 2016
217
11

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Kirsten L Bryant, Clint A Stalnecker, Daniel Zeitouni, Jennifer E Klomp, Sen Peng, Andrey P Tikunov, Venugopal Gunda, Mariaelena Pierobon, Andrew M Waters, Samuel D George,[...]. Nat Med 2019
284
11

p53 status determines the role of autophagy in pancreatic tumour development.
Mathias T Rosenfeldt, Jim O'Prey, Jennifer P Morton, Colin Nixon, Gillian MacKay, Agata Mrowinska, Amy Au, Taranjit Singh Rai, Liang Zheng, Rachel Ridgway,[...]. Nature 2013
481
11

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice.
Sunil R Hingorani, Lifu Wang, Asha S Multani, Chelsea Combs, Therese B Deramaudt, Ralph H Hruban, Anil K Rustgi, Sandy Chang, David A Tuveson. Cancer Cell 2005
11

Glucose feeds the TCA cycle via circulating lactate.
Sheng Hui, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, Tannishtha Reya, Le Zhan, Jessie Yanxiang Guo,[...]. Nature 2017
590
11

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.
Kıvanç Birsoy, Tim Wang, Walter W Chen, Elizaveta Freinkman, Monther Abu-Remaileh, David M Sabatini. Cell 2015
653
11

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids.
Jurre J Kamphorst, Justin R Cross, Jing Fan, Elisa de Stanchina, Robin Mathew, Eileen P White, Craig B Thompson, Joshua D Rabinowitz. Proc Natl Acad Sci U S A 2013
426
11

Targeting Autophagy in Cancer: Recent Advances and Future Directions.
Ravi K Amaravadi, Alec C Kimmelman, Jayanta Debnath. Cancer Discov 2019
305
10

Metabolic Interactions in the Tumor Microenvironment.
Costas A Lyssiotis, Alec C Kimmelman. Trends Cell Biol 2017
355
10

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism.
Douglas E Biancur, Joao A Paulo, Beata Małachowska, Maria Quiles Del Rey, Cristovão M Sousa, Xiaoxu Wang, Albert S W Sohn, Gerald C Chu, Steven P Gygi, J Wade Harper,[...]. Nat Commun 2017
144
10

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Richard Possemato, Kevin M Marks, Yoav D Shaul, Michael E Pacold, Dohoon Kim, Kıvanç Birsoy, Shalini Sethumadhavan, Hin-Koon Woo, Hyun G Jang, Abhishek K Jha,[...]. Nature 2011
10

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Jared R Mayers, Margaret E Torrence, Laura V Danai, Thales Papagiannakopoulos, Shawn M Davidson, Matthew R Bauer, Allison N Lau, Brian W Ji, Purushottam D Dixit, Aaron M Hosios,[...]. Science 2016
311
10

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.
Jessie Yanxiang Guo, Hsin-Yi Chen, Robin Mathew, Jing Fan, Anne M Strohecker, Gizem Karsli-Uzunbas, Jurre J Kamphorst, Guanghua Chen, Johanna M S Lemons, Vassiliki Karantza,[...]. Genes Dev 2011
880
10

Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Michael A Badgley, Daniel M Kremer, H Carlo Maurer, Kathleen E DelGiorno, Ho-Joon Lee, Vinee Purohit, Irina R Sagalovskiy, Alice Ma, Jonathan Kapilian, Christina E M Firl,[...]. Science 2020
284
10

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
10

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
10

Autophagy maintains tumour growth through circulating arginine.
Laura Poillet-Perez, Xiaoqi Xie, Le Zhan, Yang Yang, Daniel W Sharp, Zhixian Sherrie Hu, Xiaoyang Su, Anurag Maganti, Cherry Jiang, Wenyun Lu,[...]. Nature 2018
169
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.