A citation-based method for searching scientific literature

Alexander E Conicella, Gül H Zerze, Jeetain Mittal, Nicolas L Fawzi. Structure 2016
Times Cited: 363







List of co-cited articles
1427 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Avinash Patel, Hyun O Lee, Louise Jawerth, Shovamayee Maharana, Marcus Jahnel, Marco Y Hein, Stoyno Stoynov, Julia Mahamid, Shambaditya Saha, Titus M Franzmann,[...]. Cell 2015
59

Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization.
Amandine Molliex, Jamshid Temirov, Jihun Lee, Maura Coughlin, Anderson P Kanagaraj, Hong Joo Kim, Tanja Mittag, J Paul Taylor. Cell 2015
59

Biomolecular condensates: organizers of cellular biochemistry.
Salman F Banani, Hyun O Lee, Anthony A Hyman, Michael K Rosen. Nat Rev Mol Cell Biol 2017
44

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins.
Jie Wang, Jeong-Mo Choi, Alex S Holehouse, Hyun O Lee, Xiaojie Zhang, Marcus Jahnel, Shovamayee Maharana, Régis Lemaitre, Andrei Pozniakovsky, David Drechsel,[...]. Cell 2018
610
40

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
37

A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing.
Ailin Wang, Alexander E Conicella, Hermann Broder Schmidt, Erik W Martin, Shannon N Rhoads, Ashley N Reeb, Amanda Nourse, Daniel Ramirez Montero, Veronica H Ryan, Rajat Rohatgi,[...]. EMBO J 2018
161
33

Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels.
Masato Kato, Tina W Han, Shanhai Xie, Kevin Shi, Xinlin Du, Leeju C Wu, Hamid Mirzaei, Elizabeth J Goldsmith, Jamie Longgood, Jimin Pei,[...]. Cell 2012
31

Protein Phase Separation: A New Phase in Cell Biology.
Steven Boeynaems, Simon Alberti, Nicolas L Fawzi, Tanja Mittag, Magdalini Polymenidou, Frederic Rousseau, Joost Schymkowitz, James Shorter, Benjamin Wolozin, Ludo Van Den Bosch,[...]. Trends Cell Biol 2018
748
31

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins.
Yuan Lin, David S W Protter, Michael K Rosen, Roy Parker. Mol Cell 2015
807
30

Phase transitions in the assembly of multivalent signalling proteins.
Pilong Li, Sudeep Banjade, Hui-Chun Cheng, Soyeon Kim, Baoyu Chen, Liang Guo, Marc Llaguno, Javoris V Hollingsworth, David S King, Salman F Banani,[...]. Nature 2012
30

TDP-43 α-helical structure tunes liquid-liquid phase separation and function.
Alexander E Conicella, Gregory L Dignon, Gül H Zerze, Hermann Broder Schmidt, Alexandra M D'Ordine, Young C Kim, Rajat Rohatgi, Yuna M Ayala, Jeetain Mittal, Nicolas L Fawzi. Proc Natl Acad Sci U S A 2020
98
29

Tau protein liquid-liquid phase separation can initiate tau aggregation.
Susanne Wegmann, Bahareh Eftekharzadeh, Katharina Tepper, Katarzyna M Zoltowska, Rachel E Bennett, Simon Dujardin, Pawel R Laskowski, Danny MacKenzie, Tarun Kamath, Caitlin Commins,[...]. EMBO J 2018
350
28

Germline P granules are liquid droplets that localize by controlled dissolution/condensation.
Clifford P Brangwynne, Christian R Eckmann, David S Courson, Agata Rybarska, Carsten Hoege, Jöbin Gharakhani, Frank Jülicher, Anthony A Hyman. Science 2009
28

Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II.
Kathleen A Burke, Abigail M Janke, Christy L Rhine, Nicolas L Fawzi. Mol Cell 2015
424
27

Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.
Zachary Monahan, Veronica H Ryan, Abigail M Janke, Kathleen A Burke, Shannon N Rhoads, Gül H Zerze, Robert O'Meally, Gregory L Dignon, Alexander E Conicella, Wenwei Zheng,[...]. EMBO J 2017
316
27

RNA buffers the phase separation behavior of prion-like RNA binding proteins.
Shovamayee Maharana, Jie Wang, Dimitrios K Papadopoulos, Doris Richter, Andrey Pozniakovsky, Ina Poser, Marc Bickle, Sandra Rizk, Jordina Guillén-Boixet, Titus M Franzmann,[...]. Science 2018
433
27

Liquid phase condensation in cell physiology and disease.
Yongdae Shin, Clifford P Brangwynne. Science 2017
27

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.
Jacob R Mann, Amanda M Gleixner, Jocelyn C Mauna, Edward Gomes, Michael R DeChellis-Marks, Patrick G Needham, Katie E Copley, Bryan Hurtle, Bede Portz, Noah J Pyles,[...]. Neuron 2019
193
26

Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles.
Timothy J Nott, Evangelia Petsalaki, Patrick Farber, Dylan Jervis, Eden Fussner, Anne Plochowietz, Timothy D Craggs, David P Bazett-Jones, Tony Pawson, Julie D Forman-Kay,[...]. Mol Cell 2015
812
26

The role of liquid-liquid phase separation in aggregation of the TDP-43 low-complexity domain.
W Michael Babinchak, Raza Haider, Benjamin K Dumm, Prottusha Sarkar, Krystyna Surewicz, Jin-Kyu Choi, Witold K Surewicz. J Biol Chem 2019
108
25


ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function.
Tetsuro Murakami, Seema Qamar, Julie Qiaojin Lin, Gabriele S Kaminski Schierle, Eric Rees, Akinori Miyashita, Ana R Costa, Roger B Dodd, Fiona T S Chan, Claire H Michel,[...]. Neuron 2015
452
24

Molecular interactions underlying liquid-liquid phase separation of the FUS low-complexity domain.
Anastasia C Murthy, Gregory L Dignon, Yelena Kan, Gül H Zerze, Sapun H Parekh, Jeetain Mittal, Nicolas L Fawzi. Nat Struct Mol Biol 2019
181
24

Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death.
Fatima Gasset-Rosa, Shan Lu, Haiyang Yu, Cong Chen, Ze'ev Melamed, Lin Guo, James Shorter, Sandrine Da Cruz, Don W Cleveland. Neuron 2019
166
23

Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains.
Dylan T Murray, Masato Kato, Yi Lin, Kent R Thurber, Ivan Hung, Steven L McKnight, Robert Tycko. Cell 2017
333
23

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.
Seema Qamar, GuoZhen Wang, Suzanne J Randle, Francesco Simone Ruggeri, Juan A Varela, Julie Qiaojin Lin, Emma C Phillips, Akinori Miyashita, Declan Williams, Florian Ströhl,[...]. Cell 2018
351
22

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
Ian R Mackenzie, Alexandra M Nicholson, Mohona Sarkar, James Messing, Maria D Purice, Cyril Pottier, Kavya Annu, Matt Baker, Ralph B Perkerson, Aishe Kurti,[...]. Neuron 2017
315
22

Liquid-liquid phase separation in biology.
Anthony A Hyman, Christoph A Weber, Frank Jülicher. Annu Rev Cell Dev Biol 2014
21

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.
Saumya Jain, Joshua R Wheeler, Robert W Walters, Anurag Agrawal, Anthony Barsic, Roy Parker. Cell 2016
667
21

Valence and patterning of aromatic residues determine the phase behavior of prion-like domains.
Erik W Martin, Alex S Holehouse, Ivan Peran, Mina Farag, J Jeremias Incicco, Anne Bremer, Christy R Grace, Andrea Soranno, Rohit V Pappu, Tanja Mittag. Science 2020
214
21

Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization.
Leeanne McGurk, Edward Gomes, Lin Guo, Jelena Mojsilovic-Petrovic, Van Tran, Robert G Kalb, James Shorter, Nancy M Bonini. Mol Cell 2018
182
20

Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation.
Veronica H Ryan, Gregory L Dignon, Gül H Zerze, Charlene V Chabata, Rute Silva, Alexander E Conicella, Joshua Amaya, Kathleen A Burke, Jeetain Mittal, Nicolas L Fawzi. Mol Cell 2018
184
20

Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis.
Shuo-Chien Ling, Magdalini Polymenidou, Don W Cleveland. Neuron 2013
967
19

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama, Kenji Ikeda, Takashi Nonaka, Hiroshi Mori, David Mann, Kuniaki Tsuchiya, Mari Yoshida, Yoshio Hashizume,[...]. Biochem Biophys Res Commun 2006
19

TAR DNA-binding protein 43 (TDP-43) liquid-liquid phase separation is mediated by just a few aromatic residues.
Hao-Ru Li, Wan-Chin Chiang, Po-Chun Chou, Won-Jing Wang, Jie-Rong Huang. J Biol Chem 2018
99
19

Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation.
Tariq Afroz, Eva-Maria Hock, Patrick Ernst, Chiara Foglieni, Melanie Jambeau, Larissa A B Gilhespy, Florent Laferriere, Zuzanna Maniecka, Andreas Plückthun, Peer Mittl,[...]. Nat Commun 2017
141
18

TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity.
Brian S Johnson, David Snead, Jonathan J Lee, J Michael McCaffery, James Shorter, Aaron D Gitler. J Biol Chem 2009
488
17

Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies.
Manuela Neumann, Linda K Kwong, Edward B Lee, Elisabeth Kremmer, Andrew Flatley, Yan Xu, Mark S Forman, Dirk Troost, Hans A Kretzschmar, John Q Trojanowski,[...]. Acta Neuropathol 2009
343
17

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules.
Peiguo Yang, Cécile Mathieu, Regina-Maria Kolaitis, Peipei Zhang, James Messing, Ugur Yurtsever, Zemin Yang, Jinjun Wu, Yuxin Li, Qingfei Pan,[...]. Cell 2020
226
17

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS.
Hong Joo Kim, Nam Chul Kim, Yong-Dong Wang, Emily A Scarborough, Jennifer Moore, Zamia Diaz, Kyle S MacLea, Brian Freibaum, Songqing Li, Amandine Molliex,[...]. Nature 2013
908
17

Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Mario Hofweber, Saskia Hutten, Benjamin Bourgeois, Emil Spreitzer, Annika Niedner-Boblenz, Martina Schifferer, Marc-David Ruepp, Mikael Simons, Dierk Niessing, Tobias Madl,[...]. Cell 2018
277
16

Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains.
Lin Guo, Hong Joo Kim, Hejia Wang, John Monaghan, Fernande Freyermuth, Julie C Sung, Kevin O'Donovan, Charlotte M Fare, Zamia Diaz, Nikita Singh,[...]. Cell 2018
223
16

Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.
Steven Boeynaems, Elke Bogaert, Denes Kovacs, Albert Konijnenberg, Evy Timmerman, Alex Volkov, Mainak Guharoy, Mathias De Decker, Tom Jaspers, Veronica H Ryan,[...]. Mol Cell 2017
273
16

Liquid-liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau.
Susmitha Ambadipudi, Jacek Biernat, Dietmar Riedel, Eckhard Mandelkow, Markus Zweckstetter. Nat Commun 2017
287
16

Phase separation of a yeast prion protein promotes cellular fitness.
Titus M Franzmann, Marcus Jahnel, Andrei Pozniakovsky, Julia Mahamid, Alex S Holehouse, Elisabeth Nüske, Doris Richter, Wolfgang Baumeister, Stephan W Grill, Rohit V Pappu,[...]. Science 2018
297
16

Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation.
Jacob P Brady, Patrick J Farber, Ashok Sekhar, Yi-Hsuan Lin, Rui Huang, Alaji Bah, Timothy J Nott, Hue Sun Chan, Andrew J Baldwin, Julie D Forman-Kay,[...]. Proc Natl Acad Sci U S A 2017
183
16

The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics.
Shana Elbaum-Garfinkle, Younghoon Kim, Krzysztof Szczepaniak, Carlos Chih-Hsiung Chen, Christian R Eckmann, Sua Myong, Clifford P Brangwynne. Proc Natl Acad Sci U S A 2015
554
16

Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets.
Yongdae Shin, Joel Berry, Nicole Pannucci, Mikko P Haataja, Jared E Toettcher, Clifford P Brangwynne. Cell 2017
327
16

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.
T J Kwiatkowski, D A Bosco, A L Leclerc, E Tamrazian, C R Vanderburg, C Russ, A Davis, J Gilchrist, E J Kasarskis, T Munsat,[...]. Science 2009
15

Decoding ALS: from genes to mechanism.
J Paul Taylor, Robert H Brown, Don W Cleveland. Nature 2016
979
15


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.