A citation-based method for searching scientific literature

Y Hu, H Su, C Liu, Z Wang, L Huang, Q Wang, S Liu, S Chen, J Zhou, P Li, Z Chen, H Liu, G Qing. Oncogene 2017
Times Cited: 27







List of co-cited articles
230 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival.
Timothy R Peterson, Mathieu Laplante, Carson C Thoreen, Yasemin Sancak, Seong A Kang, W Michael Kuehl, Nathanael S Gray, David M Sabatini. Cell 2009
823
48


mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.
Daming Gao, Hiroyuki Inuzuka, Meng-Kwang Marcus Tan, Hidefumi Fukushima, Jason W Locasale, Pengda Liu, Lixin Wan, Bo Zhai, Y Rebecca Chin, Shavali Shaik,[...]. Mol Cell 2011
182
33

mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR.
Shanshan Duan, Jeffrey R Skaar, Shafi Kuchay, Alfredo Toschi, Naama Kanarek, Yinon Ben-Neriah, Michele Pagano. Mol Cell 2011
153
33

An evolving role for DEPTOR in tumor development and progression.
Zhiwei Wang, Jiateng Zhong, Hiroyuki Inuzuka, Daming Gao, Shavali Shaik, Fazlul H Sarkar, Wenyi Wei. Neoplasia 2012
47
29

DEPTOR at the Nexus of Cancer, Metabolism, and Immunity.
Alexandre Caron, David M Briscoe, Denis Richard, Mathieu Laplante. Physiol Rev 2018
39
25

DEPTOR has growth suppression activity against pancreatic cancer cells.
Hua Li, Grace Y Sun, Yongchao Zhao, Dafydd Thomas, Joel K Greenson, Mark M Zalupski, Edgar Ben-Josef, Yi Sun. Oncotarget 2014
23
26

Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells.
Valeria Catena, Tiziana Bruno, Francesca De Nicola, Frauke Goeman, Matteo Pallocca, Simona Iezzi, Cristina Sorino, Giovanni Cigliana, Aristide Floridi, Giovanni Blandino,[...]. Oncotarget 2016
17
35


Cytotoxic Properties of a DEPTOR-mTOR Inhibitor in Multiple Myeloma Cells.
Yijiang Shi, Tracy R Daniels-Wells, Patrick Frost, Jihye Lee, Richard S Finn, Carolyne Bardeleben, Manuel L Penichet, Michael E Jung, Joseph Gera, Alan Lichtenstein. Cancer Res 2016
14
42

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
22

Deptor enhances triple-negative breast cancer metastasis and chemoresistance through coupling to survivin expression.
Jenny G Parvani, Gangarao Davuluri, Michael K Wendt, Christine Espinosa, Maozhen Tian, David Danielpour, Khalid Sossey-Alaoui, William P Schiemann. Neoplasia 2015
33
18

mTOR: from growth signal integration to cancer, diabetes and ageing.
Roberto Zoncu, Alejo Efeyan, David M Sabatini. Nat Rev Mol Cell Biol 2011
18

Reciprocal Negative Regulation between EGFR and DEPTOR Plays an Important Role in the Progression of Lung Adenocarcinoma.
Xuefeng Zhou, Jialong Guo, Yanmei Ji, Gaofeng Pan, Tao Liu, Hua Zhu, Jinping Zhao. Mol Cancer Res 2016
18
27


mTOR signaling in growth control and disease.
Mathieu Laplante, David M Sabatini. Cell 2012
18

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
484
18

Notch dimerization is required for leukemogenesis and T-cell development.
Hudan Liu, Anthony W S Chi, Kelly L Arnett, Mark Y Chiang, Lanwei Xu, Olga Shestova, Hongfang Wang, Yue-Ming Li, Avinash Bhandoola, Jon C Aster,[...]. Genes Dev 2010
51
18

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.
Andrew P Weng, John M Millholland, Yumi Yashiro-Ohtani, Marie Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G Rodriguez, Hong Sai, John Tobias,[...]. Genes Dev 2006
612
18

Deptor: not only a mTOR inhibitor.
Valeria Catena, Maurizio Fanciulli. J Exp Clin Cancer Res 2017
45
18

DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity.
Mathieu Laplante, Simon Horvat, William T Festuccia, Kivanç Birsoy, Zala Prevorsek, Alejo Efeyan, David M Sabatini. Cell Metab 2012
84
18

Functional characterization of glycine N-methyltransferase and its interactive protein DEPDC6/DEPTOR in hepatocellular carcinoma.
Chia-Hung Yen, Yao-Cheng Lu, Chung-Hsien Li, Cheng-Ming Lee, Chia-Yen Chen, Ming-Yuan Cheng, Shiu-Feng Huang, Kuen-Feng Chen, Ann-Lii Cheng, Li-Ying Liao,[...]. Mol Med 2012
48
18


Stabilization of Notch1 by the Hsp90 Chaperone Is Crucial for T-Cell Leukemogenesis.
Zhaojing Wang, Yufeng Hu, Daibiao Xiao, Jingchao Wang, Chuntao Liu, Yisheng Xu, Xiaomeng Shi, Peng Jiang, Liang Huang, Peng Li,[...]. Clin Cancer Res 2017
23
21

AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamics.
Manuela Antonioli, Federica Albiero, Francesca Nazio, Tiziana Vescovo, Ariel Basulto Perdomo, Marco Corazzari, Claudia Marsella, Pierluca Piselli, Christine Gretzmeier, Jörn Dengjel,[...]. Dev Cell 2014
86
14

DEPTOR expression negatively correlates with mTORC1 activity and tumor progression in colorectal cancer.
Er-Yong Lai, Zhen-Guo Chen, Xuan Zhou, Xiao-Rong Fan, Hua Wang, Ping-Lin Lai, Yong-Chun Su, Bai-Yu Zhang, Xiao-Chun Bai, Yun-Feng Li. Asian Pac J Cancer Prev 2014
14
28


DEPTOR regulates vascular endothelial cell activation and proinflammatory and angiogenic responses.
Sarah Bruneau, Hironao Nakayama, Craig B Woda, Evelyn A Flynn, David M Briscoe. Blood 2013
29
14

DEPTOR promotes survival of cervical squamous cell carcinoma cells and its silencing induces apoptosis through downregulating PI3K/AKT and by up-regulating p38 MAP kinase.
Kalanghad Puthankalam Srinivas, Remadevi Viji, Vipin Mohan Dan, Indira Sukumaran Sajitha, Rajappan Prakash, Puthan Valappil Rahul, Thankayyan R Santhoshkumar, Subhadra Lakshmi, Madhavan Radhakrishna Pillai. Oncotarget 2016
25
16

DEPTOR is linked to a TORC1-p21 survival proliferation pathway in multiple myeloma cells.
Yonghui Yang, Carolyne Bardeleben, Patrick Frost, Bao Hoang, Yijiang Shi, Richard Finn, Joseph Gera, Alan Lichtenstein. Genes Cancer 2014
15
26



The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia.
Benjamin J Thompson, Silvia Buonamici, Maria Luisa Sulis, Teresa Palomero, Tomas Vilimas, Giuseppe Basso, Adolfo Ferrando, Iannis Aifantis. J Exp Med 2007
341
14

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
648
14

Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation.
Zhuo-Xian Meng, Siming Li, Lin Wang, Hwi Jin Ko, Yongjin Lee, Dae Young Jung, Mitsuharu Okutsu, Zhen Yan, Jason K Kim, Jiandie D Lin. Nat Med 2013
77
14

Structure-activity relationship study of small molecule inhibitors of the DEPTOR-mTOR interaction.
Jihye Lee, Yijiang Shi, Mario Vega, Yonghui Yang, Joseph Gera, Michael E Jung, Alan Lichtenstein. Bioorg Med Chem Lett 2017
9
44

DEP domains: structurally similar but functionally different.
Sarah V Consonni, Madelon M Maurice, Johannes L Bos. Nat Rev Mol Cell Biol 2014
38
14


Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action.
Kenta Hara, Yoshiko Maruki, Xiaomeng Long, Ken-ichi Yoshino, Noriko Oshiro, Sujuti Hidayat, Chiharu Tokunaga, Joseph Avruch, Kazuyoshi Yonezawa. Cell 2002
14

Synergistic Drug Combinations with a CDK4/6 Inhibitor in T-cell Acute Lymphoblastic Leukemia.
Yana Pikman, Gabriela Alexe, Giovanni Roti, Amy Saur Conway, Andrew Furman, Emily S Lee, Andrew E Place, Sunkyu Kim, Chitra Saran, Rebecca Modiste,[...]. Clin Cancer Res 2017
56
14

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia.
Daniel Herranz, Alberto Ambesi-Impiombato, Teresa Palomero, Stephanie A Schnell, Laura Belver, Agnieszka A Wendorff, Luyao Xu, Mireia Castillo-Martin, David Llobet-Navás, Carlos Cordon-Cardo,[...]. Nat Med 2014
233
14

Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status.
A Andersson, C Ritz, D Lindgren, P Edén, C Lassen, J Heldrup, T Olofsson, J Råde, M Fontes, A Porwit-Macdonald,[...]. Leukemia 2007
134
14

SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival.
Hexiu Su, Juncheng Hu, Liang Huang, Yang Yang, Morgan Thenoz, Anna Kuchmiy, Yufeng Hu, Peng Li, Hui Feng, Yu Zhou,[...]. Nat Commun 2018
9
44

The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth.
Danrui Cui, Xiaoqing Dai, Jianfeng Shu, Ying Ma, Dongping Wei, Xiufang Xiong, Yongchao Zhao. Cell Death Differ 2020
17
23

The Baf60c/Deptor pathway links skeletal muscle inflammation to glucose homeostasis in obesity.
Zhuo-Xian Meng, Lin Wang, Yuanyuan Xiao, Jiandie D Lin. Diabetes 2014
29
11

DEP domains: More than just membrane anchors.
Songhai Chen, Heidi E Hamm. Dev Cell 2006
32
11

mTORC1 and mTORC2 in cancer and the tumor microenvironment.
L C Kim, R S Cook, J Chen. Oncogene 2017
185
11

Rapid mitogenic regulation of the mTORC1 inhibitor, DEPTOR, by phosphatidic acid.
Mee-Sup Yoon, Christina L Rosenberger, Cong Wu, Nga Truong, Jonathan V Sweedler, Jie Chen. Mol Cell 2015
62
11

Single Nucleotide Polymorphisms within the 8Q24 Region are Not Associated with the Risk of Intraductal Papillary Mucinous Neoplasms of the Pancreas.
Nikola Panic, Alberto Larghi, Rosarita Amore, Roberta Pastorino, Milutin Bulajic, Guido Costamagna, Stefania Boccia. J Gastrointestin Liver Dis 2016
7
42

DEPTOR-related mTOR suppression is involved in metformin's anti-cancer action in human liver cancer cells.
Akio Obara, Yoshihito Fujita, Abulizi Abudukadier, Toru Fukushima, Yasuo Oguri, Masahito Ogura, Shin-Ichi Harashima, Masaya Hosokawa, Nobuya Inagaki. Biochem Biophys Res Commun 2015
21
14


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.