Takatoshi Chinen, Arun K Kannan, Andrew G Levine, Xiying Fan, Ulf Klein, Ye Zheng, Georg Gasteiger, Yongqiang Feng, Jason D Fontenot, Alexander Y Rudensky. Nat Immunol 2016
Times Cited: 308
Times Cited: 308
Times Cited
Times Co-cited
Similarity
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.
S Sakaguchi, N Sakaguchi, M Asano, M Itoh, M Toda. J Immunol 1995
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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.
Jason D Fontenot, Marc A Gavin, Alexander Y Rudensky. Nat Immunol 2003
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Control of regulatory T cell development by the transcription factor Foxp3.
Shohei Hori, Takashi Nomura, Shimon Sakaguchi. Science 2003
Shohei Hori, Takashi Nomura, Shimon Sakaguchi. Science 2003
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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3.
C L Bennett, J Christie, F Ramsdell, M E Brunkow, P J Ferguson, L Whitesell, T E Kelly, F T Saulsbury, P F Chance, H D Ochs. Nat Genet 2001
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A function for interleukin 2 in Foxp3-expressing regulatory T cells.
Jason D Fontenot, Jeffrey P Rasmussen, Marc A Gavin, Alexander Y Rudensky. Nat Immunol 2005
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Regulatory T cells: mechanisms of differentiation and function.
Steven Z Josefowicz, Li-Fan Lu, Alexander Y Rudensky. Annu Rev Immunol 2012
Steven Z Josefowicz, Li-Fan Lu, Alexander Y Rudensky. Annu Rev Immunol 2012
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CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells.
Pushpa Pandiyan, Lixin Zheng, Satoru Ishihara, Jennifer Reed, Michael J Lenardo. Nat Immunol 2007
Pushpa Pandiyan, Lixin Zheng, Satoru Ishihara, Jennifer Reed, Michael J Lenardo. Nat Immunol 2007
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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3.
WanJun Chen, Wenwen Jin, Neil Hardegen, Ke-Jian Lei, Li Li, Nancy Marinos, George McGrady, Sharon M Wahl. J Exp Med 2003
WanJun Chen, Wenwen Jin, Neil Hardegen, Ke-Jian Lei, Li Li, Nancy Marinos, George McGrady, Sharon M Wahl. J Exp Med 2003
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Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor.
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Continuous requirement for the TCR in regulatory T cell function.
Andrew G Levine, Aaron Arvey, Wei Jin, Alexander Y Rudensky. Nat Immunol 2014
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Regulatory T cells and immune tolerance.
Shimon Sakaguchi, Tomoyuki Yamaguchi, Takashi Nomura, Masahiro Ono. Cell 2008
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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.
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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression.
Silvia Deaglio, Karen M Dwyer, Wenda Gao, David Friedman, Anny Usheva, Anna Erat, Jiang-Fan Chen, Keiichii Enjyoji, Joel Linden, Mohamed Oukka,[...]. J Exp Med 2007
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Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation.
Ricardo J Miragaia, Tomás Gomes, Agnieszka Chomka, Laura Jardine, Angela Riedel, Ahmed N Hegazy, Natasha Whibley, Andrea Tucci, Xi Chen, Ida Lindeman,[...]. Immunity 2019
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CTLA-4 control over Foxp3+ regulatory T cell function.
Kajsa Wing, Yasushi Onishi, Paz Prieto-Martin, Tomoyuki Yamaguchi, Makoto Miyara, Zoltan Fehervari, Takashi Nomura, Shimon Sakaguchi. Science 2008
Kajsa Wing, Yasushi Onishi, Paz Prieto-Martin, Tomoyuki Yamaguchi, Makoto Miyara, Zoltan Fehervari, Takashi Nomura, Shimon Sakaguchi. Science 2008
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Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate.
Ye Zheng, Steven Josefowicz, Ashutosh Chaudhry, Xiao P Peng, Katherine Forbush, Alexander Y Rudensky. Nature 2010
Ye Zheng, Steven Josefowicz, Ashutosh Chaudhry, Xiao P Peng, Katherine Forbush, Alexander Y Rudensky. Nature 2010
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An essential role for Scurfin in CD4+CD25+ T regulatory cells.
Roli Khattri, Tom Cox, Sue-Ann Yasayko, Fred Ramsdell. Nat Immunol 2003
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How regulatory T cells work.
Dario A A Vignali, Lauren W Collison, Creg J Workman. Nat Rev Immunol 2008
Dario A A Vignali, Lauren W Collison, Creg J Workman. Nat Rev Immunol 2008
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Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus.
Yongqiang Feng, Aaron Arvey, Takatoshi Chinen, Joris van der Veeken, Georg Gasteiger, Alexander Y Rudensky. Cell 2014
Yongqiang Feng, Aaron Arvey, Takatoshi Chinen, Joris van der Veeken, Georg Gasteiger, Alexander Y Rudensky. Cell 2014
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Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo.
Xuyu Zhou, Samantha L Bailey-Bucktrout, Lukas T Jeker, Cristina Penaranda, Marc Martínez-Llordella, Meredith Ashby, Maki Nakayama, Wendy Rosenthal, Jeffrey A Bluestone. Nat Immunol 2009
Xuyu Zhou, Samantha L Bailey-Bucktrout, Lukas T Jeker, Cristina Penaranda, Marc Martínez-Llordella, Meredith Ashby, Maki Nakayama, Wendy Rosenthal, Jeffrey A Bluestone. Nat Immunol 2009
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Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization.
Ruka Setoguchi, Shohei Hori, Takeshi Takahashi, Shimon Sakaguchi. J Exp Med 2005
Ruka Setoguchi, Shohei Hori, Takeshi Takahashi, Shimon Sakaguchi. J Exp Med 2005
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Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice.
Jeong M Kim, Jeffrey P Rasmussen, Alexander Y Rudensky. Nat Immunol 2007
Jeong M Kim, Jeffrey P Rasmussen, Alexander Y Rudensky. Nat Immunol 2007
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IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.
Matthew A Burchill, Jianying Yang, Christine Vogtenhuber, Bruce R Blazar, Michael A Farrar. J Immunol 2007
Matthew A Burchill, Jianying Yang, Christine Vogtenhuber, Bruce R Blazar, Michael A Farrar. J Immunol 2007
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Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance.
Xuefang Cao, Sheng F Cai, Todd A Fehniger, Jiling Song, Lynne I Collins, David R Piwnica-Worms, Timothy J Ley. Immunity 2007
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Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.
Noriko Komatsu, Kazuo Okamoto, Shinichiro Sawa, Tomoki Nakashima, Masatsugu Oh-hora, Tatsuhiko Kodama, Sakae Tanaka, Jeffrey A Bluestone, Hiroshi Takayanagi. Nat Med 2014
Noriko Komatsu, Kazuo Okamoto, Shinichiro Sawa, Tomoki Nakashima, Masatsugu Oh-hora, Tatsuhiko Kodama, Sakae Tanaka, Jeffrey A Bluestone, Hiroshi Takayanagi. Nat Med 2014
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A special population of regulatory T cells potentiates muscle repair.
Dalia Burzyn, Wilson Kuswanto, Dmitriy Kolodin, Jennifer L Shadrach, Massimiliano Cerletti, Young Jang, Esen Sefik, Tze Guan Tan, Amy J Wagers, Christophe Benoist,[...]. Cell 2013
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Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4.
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Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo.
Mahesh Yadav, Cedric Louvet, Dan Davini, James M Gardner, Marc Martinez-Llordella, Samantha Bailey-Bucktrout, Bryan A Anthony, Francis M Sverdrup, Richard Head, Daniel J Kuster,[...]. J Exp Med 2012
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Emerging Functions of Regulatory T Cells in Tissue Homeostasis.
Amit Sharma, Dipayan Rudra. Front Immunol 2018
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Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation.
Nicholas Arpaia, Clarissa Campbell, Xiying Fan, Stanislav Dikiy, Joris van der Veeken, Paul deRoos, Hui Liu, Justin R Cross, Klaus Pfeffer, Paul J Coffer,[...]. Nature 2013
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mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.
Hu Zeng, Kai Yang, Caryn Cloer, Geoffrey Neale, Peter Vogel, Hongbo Chi. Nature 2013
Hu Zeng, Kai Yang, Caryn Cloer, Geoffrey Neale, Peter Vogel, Hongbo Chi. Nature 2013
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Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces.
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Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.
Giovanna Borsellino, Markus Kleinewietfeld, Diletta Di Mitri, Alexander Sternjak, Adamo Diamantini, Raffaella Giometto, Sabine Höpner, Diego Centonze, Giorgio Bernardi, Maria Luisa Dell'Acqua,[...]. Blood 2007
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Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters.
Markus Feuerer, Laura Herrero, Daniela Cipolletta, Afia Naaz, Jamie Wong, Ali Nayer, Jongsoon Lee, Allison B Goldfine, Christophe Benoist, Steven Shoelson,[...]. Nat Med 2009
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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy.
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Interleukin-2 and regulatory T cells in graft-versus-host disease.
John Koreth, Ken-ichi Matsuoka, Haesook T Kim, Sean M McDonough, Bhavjot Bindra, Edwin P Alyea, Philippe Armand, Corey Cutler, Vincent T Ho, Nathaniel S Treister,[...]. N Engl J Med 2011
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CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2.
Thomas R Malek, Aixin Yu, Vladimir Vincek, Paul Scibelli, Lin Kong. Immunity 2002
Thomas R Malek, Aixin Yu, Vladimir Vincek, Paul Scibelli, Lin Kong. Immunity 2002
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Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism.
David C Gondek, Li-Fan Lu, Sergio A Quezada, Shimon Sakaguchi, Randolph J Noelle. J Immunol 2005
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Past, Present, and Future of Regulatory T Cell Therapy in Transplantation and Autoimmunity.
Marco Romano, Giorgia Fanelli, Caraugh Jane Albany, Giulio Giganti, Giovanna Lombardi. Front Immunol 2019
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Revisiting IL-2: Biology and therapeutic prospects.
Abul K Abbas, Eleonora Trotta, Dimitre R Simeonov, Alexander Marson, Jeffrey A Bluestone. Sci Immunol 2018
Abul K Abbas, Eleonora Trotta, Dimitre R Simeonov, Alexander Marson, Jeffrey A Bluestone. Sci Immunol 2018
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Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells.
Jonathan M Weiss, Angelina M Bilate, Michael Gobert, Yi Ding, Maria A Curotto de Lafaille, Christopher N Parkhurst, Huizhong Xiong, Jayashree Dolpady, Alan B Frey, Maria Grazia Ruocco,[...]. J Exp Med 2012
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Human T regulatory cells can use the perforin pathway to cause autologous target cell death.
William J Grossman, James W Verbsky, Winfried Barchet, Marco Colonna, John P Atkinson, Timothy J Ley. Immunity 2004
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Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses.
Shimon Sakaguchi. Annu Rev Immunol 2004
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Foxp3-dependent programme of regulatory T-cell differentiation.
Marc A Gavin, Jeffrey P Rasmussen, Jason D Fontenot, Valeria Vasta, Vincent C Manganiello, Joseph A Beavo, Alexander Y Rudensky. Nature 2007
Marc A Gavin, Jeffrey P Rasmussen, Jason D Fontenot, Valeria Vasta, Vincent C Manganiello, Joseph A Beavo, Alexander Y Rudensky. Nature 2007
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Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.
Marco De Simone, Alberto Arrigoni, Grazisa Rossetti, Paola Gruarin, Valeria Ranzani, Claudia Politano, Raoul J P Bonnal, Elena Provasi, Maria Lucia Sarnicola, Ilaria Panzeri,[...]. Immunity 2016
Marco De Simone, Alberto Arrigoni, Grazisa Rossetti, Paola Gruarin, Valeria Ranzani, Claudia Politano, Raoul J P Bonnal, Elena Provasi, Maria Lucia Sarnicola, Ilaria Panzeri,[...]. Immunity 2016
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A Distinct Function of Regulatory T Cells in Tissue Protection.
Nicholas Arpaia, Jesse A Green, Bruno Moltedo, Aaron Arvey, Saskia Hemmers, Shaopeng Yuan, Piper M Treuting, Alexander Y Rudensky. Cell 2015
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Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.
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Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation.
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PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells.
Daniela Cipolletta, Markus Feuerer, Amy Li, Nozomu Kamei, Jongsoon Lee, Steven E Shoelson, Christophe Benoist, Diane Mathis. Nature 2012
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7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.