Takatoshi Chinen, Arun K Kannan, Andrew G Levine, Xiying Fan, Ulf Klein, Ye Zheng, Georg Gasteiger, Yongqiang Feng, Jason D Fontenot, Alexander Y Rudensky. Nat Immunol 2016
Times Cited: 431
Times Cited: 431
Times Cited
Times Co-cited
Similarity
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.
Jason D Fontenot, Marc A Gavin, Alexander Y Rudensky. Nat Immunol 2003
Jason D Fontenot, Marc A Gavin, Alexander Y Rudensky. Nat Immunol 2003
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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.
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CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells.
Pushpa Pandiyan, Lixin Zheng, Satoru Ishihara, Jennifer Reed, Michael J Lenardo. Nat Immunol 2007
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Regulatory T cells and immune tolerance.
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Chan-Wang Joaquim Lio, Chyi-Song Hsieh. Immunity 2008
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Interleukin-2 and regulatory T cells in graft-versus-host disease.
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Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces.
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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression.
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PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells.
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Continuous requirement for the TCR in regulatory T cell function.
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Regulatory T Cells and Human Disease.
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CTLA-4 control over Foxp3+ regulatory T cell function.
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An essential role for Scurfin in CD4+CD25+ T regulatory cells.
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Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor.
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A special population of regulatory T cells potentiates muscle repair.
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Molecular mechanisms of treg-mediated T cell suppression.
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The role of interleukin-2 during homeostasis and activation of the immune system.
Onur Boyman, Jonathan Sprent. Nat Rev Immunol 2012
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Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis.
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Immunological and clinical effects of low-dose interleukin-2 across 11 autoimmune diseases in a single, open clinical trial.
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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3.
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Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo.
Xuyu Zhou, Samantha L Bailey-Bucktrout, Lukas T Jeker, Cristina Penaranda, Marc Martínez-Llordella, Meredith Ashby, Maki Nakayama, Wendy Rosenthal, Jeffrey A Bluestone. Nat Immunol 2009
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Stability of the regulatory T cell lineage in vivo.
Yuri P Rubtsov, Rachel E Niec, Steven Josefowicz, Li Li, Jaime Darce, Diane Mathis, Christophe Benoist, Alexander Y Rudensky. Science 2010
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The inhibitory cytokine IL-35 contributes to regulatory T-cell function.
Lauren W Collison, Creg J Workman, Timothy T Kuo, Kelli Boyd, Yao Wang, Kate M Vignali, Richard Cross, David Sehy, Richard S Blumberg, Dario A A Vignali. Nature 2007
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A Distinct Function of Regulatory T Cells in Tissue Protection.
Nicholas Arpaia, Jesse A Green, Bruno Moltedo, Aaron Arvey, Saskia Hemmers, Shaopeng Yuan, Piper M Treuting, Alexander Y Rudensky. Cell 2015
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Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics.
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Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor.
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Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters.
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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.
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Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4.
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Regulatory T cells in autoimmune disease.
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Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4.
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Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance.
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Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus.
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High dose interleukin-2 (Aldesleukin) - expert consensus on best management practices-2014.
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Low-dose interleukin-2 treatment selectively modulates CD4(+) T cell subsets in patients with systemic lupus erythematosus.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.