Takatoshi Chinen, Arun K Kannan, Andrew G Levine, Xiying Fan, Ulf Klein, Ye Zheng, Georg Gasteiger, Yongqiang Feng, Jason D Fontenot, Alexander Y Rudensky. Nat Immunol 2016
Times Cited: 431
Times Cited: 431
Times Cited
Times Co-cited
Similarity
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.
Jason D Fontenot, Marc A Gavin, Alexander Y Rudensky. Nat Immunol 2003
Jason D Fontenot, Marc A Gavin, Alexander Y Rudensky. Nat Immunol 2003
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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.
S Sakaguchi, N Sakaguchi, M Asano, M Itoh, M Toda. J Immunol 1995
S Sakaguchi, N Sakaguchi, M Asano, M Itoh, M Toda. J Immunol 1995
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Control of regulatory T cell development by the transcription factor Foxp3.
Shohei Hori, Takashi Nomura, Shimon Sakaguchi. Science 2003
Shohei Hori, Takashi Nomura, Shimon Sakaguchi. Science 2003
14
Regulatory T cells: mechanisms of differentiation and function.
Steven Z Josefowicz, Li-Fan Lu, Alexander Y Rudensky. Annu Rev Immunol 2012
Steven Z Josefowicz, Li-Fan Lu, Alexander Y Rudensky. Annu Rev Immunol 2012
11
CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells.
Pushpa Pandiyan, Lixin Zheng, Satoru Ishihara, Jennifer Reed, Michael J Lenardo. Nat Immunol 2007
Pushpa Pandiyan, Lixin Zheng, Satoru Ishihara, Jennifer Reed, Michael J Lenardo. Nat Immunol 2007
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Regulatory T cells and immune tolerance.
Shimon Sakaguchi, Tomoyuki Yamaguchi, Takashi Nomura, Masahiro Ono. Cell 2008
Shimon Sakaguchi, Tomoyuki Yamaguchi, Takashi Nomura, Masahiro Ono. Cell 2008
10
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.
Noriko Komatsu, Kazuo Okamoto, Shinichiro Sawa, Tomoki Nakashima, Masatsugu Oh-hora, Tatsuhiko Kodama, Sakae Tanaka, Jeffrey A Bluestone, Hiroshi Takayanagi. Nat Med 2014
Noriko Komatsu, Kazuo Okamoto, Shinichiro Sawa, Tomoki Nakashima, Masatsugu Oh-hora, Tatsuhiko Kodama, Sakae Tanaka, Jeffrey A Bluestone, Hiroshi Takayanagi. Nat Med 2014
10
A two-step process for thymic regulatory T cell development.
Chan-Wang Joaquim Lio, Chyi-Song Hsieh. Immunity 2008
Chan-Wang Joaquim Lio, Chyi-Song Hsieh. Immunity 2008
9
Interleukin-2 and regulatory T cells in graft-versus-host disease.
John Koreth, Ken-ichi Matsuoka, Haesook T Kim, Sean M McDonough, Bhavjot Bindra, Edwin P Alyea, Philippe Armand, Corey Cutler, Vincent T Ho, Nathaniel S Treister,[...]. N Engl J Med 2011
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9
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces.
Yuri P Rubtsov, Jeffrey P Rasmussen, Emil Y Chi, Jason Fontenot, Luca Castelli, Xin Ye, Piper Treuting, Lisa Siewe, Axel Roers, William R Henderson,[...]. Immunity 2008
Yuri P Rubtsov, Jeffrey P Rasmussen, Emil Y Chi, Jason Fontenot, Luca Castelli, Xin Ye, Piper Treuting, Lisa Siewe, Axel Roers, William R Henderson,[...]. Immunity 2008
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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression.
Silvia Deaglio, Karen M Dwyer, Wenda Gao, David Friedman, Anny Usheva, Anna Erat, Jiang-Fan Chen, Keiichii Enjyoji, Joel Linden, Mohamed Oukka,[...]. J Exp Med 2007
Silvia Deaglio, Karen M Dwyer, Wenda Gao, David Friedman, Anny Usheva, Anna Erat, Jiang-Fan Chen, Keiichii Enjyoji, Joel Linden, Mohamed Oukka,[...]. J Exp Med 2007
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PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells.
Daniela Cipolletta, Markus Feuerer, Amy Li, Nozomu Kamei, Jongsoon Lee, Steven E Shoelson, Christophe Benoist, Diane Mathis. Nature 2012
Daniela Cipolletta, Markus Feuerer, Amy Li, Nozomu Kamei, Jongsoon Lee, Steven E Shoelson, Christophe Benoist, Diane Mathis. Nature 2012
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Continuous requirement for the TCR in regulatory T cell function.
Andrew G Levine, Aaron Arvey, Wei Jin, Alexander Y Rudensky. Nat Immunol 2014
Andrew G Levine, Aaron Arvey, Wei Jin, Alexander Y Rudensky. Nat Immunol 2014
8
Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy.
Wei Liao, Jian-Xin Lin, Warren J Leonard. Immunity 2013
Wei Liao, Jian-Xin Lin, Warren J Leonard. Immunity 2013
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Regulatory T Cells and Human Disease.
Shimon Sakaguchi, Norihisa Mikami, James B Wing, Atsushi Tanaka, Kenji Ichiyama, Naganari Ohkura. Annu Rev Immunol 2020
Shimon Sakaguchi, Norihisa Mikami, James B Wing, Atsushi Tanaka, Kenji Ichiyama, Naganari Ohkura. Annu Rev Immunol 2020
8
CTLA-4 control over Foxp3+ regulatory T cell function.
Kajsa Wing, Yasushi Onishi, Paz Prieto-Martin, Tomoyuki Yamaguchi, Makoto Miyara, Zoltan Fehervari, Takashi Nomura, Shimon Sakaguchi. Science 2008
Kajsa Wing, Yasushi Onishi, Paz Prieto-Martin, Tomoyuki Yamaguchi, Makoto Miyara, Zoltan Fehervari, Takashi Nomura, Shimon Sakaguchi. Science 2008
8
An essential role for Scurfin in CD4+CD25+ T regulatory cells.
Roli Khattri, Tom Cox, Sue-Ann Yasayko, Fred Ramsdell. Nat Immunol 2003
Roli Khattri, Tom Cox, Sue-Ann Yasayko, Fred Ramsdell. Nat Immunol 2003
8
Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor.
Makoto Miyara, Yumiko Yoshioka, Akihiko Kitoh, Tomoko Shima, Kajsa Wing, Akira Niwa, Christophe Parizot, Cécile Taflin, Toshio Heike, Dominique Valeyre,[...]. Immunity 2009
Makoto Miyara, Yumiko Yoshioka, Akihiko Kitoh, Tomoko Shima, Kajsa Wing, Akira Niwa, Christophe Parizot, Cécile Taflin, Toshio Heike, Dominique Valeyre,[...]. Immunity 2009
8
A special population of regulatory T cells potentiates muscle repair.
Dalia Burzyn, Wilson Kuswanto, Dmitriy Kolodin, Jennifer L Shadrach, Massimiliano Cerletti, Young Jang, Esen Sefik, Tze Guan Tan, Amy J Wagers, Christophe Benoist,[...]. Cell 2013
Dalia Burzyn, Wilson Kuswanto, Dmitriy Kolodin, Jennifer L Shadrach, Massimiliano Cerletti, Young Jang, Esen Sefik, Tze Guan Tan, Amy J Wagers, Christophe Benoist,[...]. Cell 2013
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Molecular mechanisms of treg-mediated T cell suppression.
Angelika Schmidt, Nina Oberle, Peter H Krammer. Front Immunol 2012
Angelika Schmidt, Nina Oberle, Peter H Krammer. Front Immunol 2012
7
A function for interleukin 2 in Foxp3-expressing regulatory T cells.
Jason D Fontenot, Jeffrey P Rasmussen, Marc A Gavin, Alexander Y Rudensky. Nat Immunol 2005
Jason D Fontenot, Jeffrey P Rasmussen, Marc A Gavin, Alexander Y Rudensky. Nat Immunol 2005
7
The role of interleukin-2 during homeostasis and activation of the immune system.
Onur Boyman, Jonathan Sprent. Nat Rev Immunol 2012
Onur Boyman, Jonathan Sprent. Nat Rev Immunol 2012
7
Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis.
David Saadoun, Michelle Rosenzwajg, Florence Joly, Adrien Six, Fabrice Carrat, Vincent Thibault, Damien Sene, Patrice Cacoub, David Klatzmann. N Engl J Med 2011
David Saadoun, Michelle Rosenzwajg, Florence Joly, Adrien Six, Fabrice Carrat, Vincent Thibault, Damien Sene, Patrice Cacoub, David Klatzmann. N Engl J Med 2011
7
Immunological and clinical effects of low-dose interleukin-2 across 11 autoimmune diseases in a single, open clinical trial.
Michelle Rosenzwajg, Roberta Lorenzon, Patrice Cacoub, Hang Phuong Pham, Fabien Pitoiset, Karim El Soufi, Claire RIbet, Claude Bernard, Selim Aractingi, Beatrice Banneville,[...]. Ann Rheum Dis 2019
Michelle Rosenzwajg, Roberta Lorenzon, Patrice Cacoub, Hang Phuong Pham, Fabien Pitoiset, Karim El Soufi, Claire RIbet, Claude Bernard, Selim Aractingi, Beatrice Banneville,[...]. Ann Rheum Dis 2019
7
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3.
C L Bennett, J Christie, F Ramsdell, M E Brunkow, P J Ferguson, L Whitesell, T E Kelly, F T Saulsbury, P F Chance, H D Ochs. Nat Genet 2001
C L Bennett, J Christie, F Ramsdell, M E Brunkow, P J Ferguson, L Whitesell, T E Kelly, F T Saulsbury, P F Chance, H D Ochs. Nat Genet 2001
7
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo.
Xuyu Zhou, Samantha L Bailey-Bucktrout, Lukas T Jeker, Cristina Penaranda, Marc Martínez-Llordella, Meredith Ashby, Maki Nakayama, Wendy Rosenthal, Jeffrey A Bluestone. Nat Immunol 2009
Xuyu Zhou, Samantha L Bailey-Bucktrout, Lukas T Jeker, Cristina Penaranda, Marc Martínez-Llordella, Meredith Ashby, Maki Nakayama, Wendy Rosenthal, Jeffrey A Bluestone. Nat Immunol 2009
7
Stability of the regulatory T cell lineage in vivo.
Yuri P Rubtsov, Rachel E Niec, Steven Josefowicz, Li Li, Jaime Darce, Diane Mathis, Christophe Benoist, Alexander Y Rudensky. Science 2010
Yuri P Rubtsov, Rachel E Niec, Steven Josefowicz, Li Li, Jaime Darce, Diane Mathis, Christophe Benoist, Alexander Y Rudensky. Science 2010
7
The inhibitory cytokine IL-35 contributes to regulatory T-cell function.
Lauren W Collison, Creg J Workman, Timothy T Kuo, Kelli Boyd, Yao Wang, Kate M Vignali, Richard Cross, David Sehy, Richard S Blumberg, Dario A A Vignali. Nature 2007
Lauren W Collison, Creg J Workman, Timothy T Kuo, Kelli Boyd, Yao Wang, Kate M Vignali, Richard Cross, David Sehy, Richard S Blumberg, Dario A A Vignali. Nature 2007
7
A Distinct Function of Regulatory T Cells in Tissue Protection.
Nicholas Arpaia, Jesse A Green, Bruno Moltedo, Aaron Arvey, Saskia Hemmers, Shaopeng Yuan, Piper M Treuting, Alexander Y Rudensky. Cell 2015
Nicholas Arpaia, Jesse A Green, Bruno Moltedo, Aaron Arvey, Saskia Hemmers, Shaopeng Yuan, Piper M Treuting, Alexander Y Rudensky. Cell 2015
7
Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics.
Claudio G Brunstein, Jeffrey S Miller, Qing Cao, David H McKenna, Keli L Hippen, Julie Curtsinger, Todd Defor, Bruce L Levine, Carl H June, Pablo Rubinstein,[...]. Blood 2011
Claudio G Brunstein, Jeffrey S Miller, Qing Cao, David H McKenna, Keli L Hippen, Julie Curtsinger, Todd Defor, Bruce L Levine, Carl H June, Pablo Rubinstein,[...]. Blood 2011
7
Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor.
Katherine G MacDonald, Romy E Hoeppli, Qing Huang, Jana Gillies, Dan S Luciani, Paul C Orban, Raewyn Broady, Megan K Levings. J Clin Invest 2016
Katherine G MacDonald, Romy E Hoeppli, Qing Huang, Jana Gillies, Dan S Luciani, Paul C Orban, Raewyn Broady, Megan K Levings. J Clin Invest 2016
6
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters.
Markus Feuerer, Laura Herrero, Daniela Cipolletta, Afia Naaz, Jamie Wong, Ali Nayer, Jongsoon Lee, Allison B Goldfine, Christophe Benoist, Steven Shoelson,[...]. Nat Med 2009
Markus Feuerer, Laura Herrero, Daniela Cipolletta, Afia Naaz, Jamie Wong, Ali Nayer, Jongsoon Lee, Allison B Goldfine, Christophe Benoist, Steven Shoelson,[...]. Nat Med 2009
6
Selective stimulation of T cell subsets with antibody-cytokine immune complexes.
Onur Boyman, Marek Kovar, Mark P Rubinstein, Charles D Surh, Jonathan Sprent. Science 2006
Onur Boyman, Marek Kovar, Mark P Rubinstein, Charles D Surh, Jonathan Sprent. Science 2006
6
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.
M E Brunkow, E W Jeffery, K A Hjerrild, B Paeper, L B Clark, S A Yasayko, J E Wilkinson, D Galas, S F Ziegler, F Ramsdell. Nat Genet 2001
M E Brunkow, E W Jeffery, K A Hjerrild, B Paeper, L B Clark, S A Yasayko, J E Wilkinson, D Galas, S F Ziegler, F Ramsdell. Nat Genet 2001
6
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4.
Omar S Qureshi, Yong Zheng, Kyoko Nakamura, Kesley Attridge, Claire Manzotti, Emily M Schmidt, Jennifer Baker, Louisa E Jeffery, Satdip Kaur, Zoe Briggs,[...]. Science 2011
Omar S Qureshi, Yong Zheng, Kyoko Nakamura, Kesley Attridge, Claire Manzotti, Emily M Schmidt, Jennifer Baker, Louisa E Jeffery, Satdip Kaur, Zoe Briggs,[...]. Science 2011
6
Regulatory T cells in autoimmune disease.
Margarita Dominguez-Villar, David A Hafler. Nat Immunol 2018
Margarita Dominguez-Villar, David A Hafler. Nat Immunol 2018
6
The alarmin IL-33 promotes regulatory T-cell function in the intestine.
Chris Schiering, Thomas Krausgruber, Agnieszka Chomka, Anja Fröhlich, Krista Adelmann, Elizabeth A Wohlfert, Johanna Pott, Thibault Griseri, Julia Bollrath, Ahmed N Hegazy,[...]. Nature 2014
Chris Schiering, Thomas Krausgruber, Agnieszka Chomka, Anja Fröhlich, Krista Adelmann, Elizabeth A Wohlfert, Johanna Pott, Thibault Griseri, Julia Bollrath, Ahmed N Hegazy,[...]. Nature 2014
6
Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4.
James Badger Wing, Wataru Ise, Tomohiro Kurosaki, Shimon Sakaguchi. Immunity 2014
James Badger Wing, Wataru Ise, Tomohiro Kurosaki, Shimon Sakaguchi. Immunity 2014
5
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3.
WanJun Chen, Wenwen Jin, Neil Hardegen, Ke-Jian Lei, Li Li, Nancy Marinos, George McGrady, Sharon M Wahl. J Exp Med 2003
WanJun Chen, Wenwen Jin, Neil Hardegen, Ke-Jian Lei, Li Li, Nancy Marinos, George McGrady, Sharon M Wahl. J Exp Med 2003
5
Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance.
Xuefang Cao, Sheng F Cai, Todd A Fehniger, Jiling Song, Lynne I Collins, David R Piwnica-Worms, Timothy J Ley. Immunity 2007
Xuefang Cao, Sheng F Cai, Todd A Fehniger, Jiling Song, Lynne I Collins, David R Piwnica-Worms, Timothy J Ley. Immunity 2007
5
Signaling and Function of Interleukin-2 in T Lymphocytes.
Sarah H Ross, Doreen A Cantrell. Annu Rev Immunol 2018
Sarah H Ross, Doreen A Cantrell. Annu Rev Immunol 2018
5
Human T regulatory cells can use the perforin pathway to cause autologous target cell death.
William J Grossman, James W Verbsky, Winfried Barchet, Marco Colonna, John P Atkinson, Timothy J Ley. Immunity 2004
William J Grossman, James W Verbsky, Winfried Barchet, Marco Colonna, John P Atkinson, Timothy J Ley. Immunity 2004
5
5
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
5
Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial.
Agnès Hartemann, Gilbert Bensimon, Christine A Payan, Sophie Jacqueminet, Olivier Bourron, Nathalie Nicolas, Michèle Fonfrede, Michelle Rosenzwajg, Claude Bernard, David Klatzmann. Lancet Diabetes Endocrinol 2013
Agnès Hartemann, Gilbert Bensimon, Christine A Payan, Sophie Jacqueminet, Olivier Bourron, Nathalie Nicolas, Michèle Fonfrede, Michelle Rosenzwajg, Claude Bernard, David Klatzmann. Lancet Diabetes Endocrinol 2013
5
Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus.
Yongqiang Feng, Aaron Arvey, Takatoshi Chinen, Joris van der Veeken, Georg Gasteiger, Alexander Y Rudensky. Cell 2014
Yongqiang Feng, Aaron Arvey, Takatoshi Chinen, Joris van der Veeken, Georg Gasteiger, Alexander Y Rudensky. Cell 2014
5
High dose interleukin-2 (Aldesleukin) - expert consensus on best management practices-2014.
Janice P Dutcher, Douglas J Schwartzentruber, Howard L Kaufman, Sanjiv S Agarwala, Ahmad A Tarhini, James N Lowder, Michael B Atkins. J Immunother Cancer 2014
Janice P Dutcher, Douglas J Schwartzentruber, Howard L Kaufman, Sanjiv S Agarwala, Ahmad A Tarhini, James N Lowder, Michael B Atkins. J Immunother Cancer 2014
5
Low-dose interleukin-2 treatment selectively modulates CD4(+) T cell subsets in patients with systemic lupus erythematosus.
Jing He, Xia Zhang, Yunbo Wei, Xiaolin Sun, Yaping Chen, Jun Deng, Yuebo Jin, Yuzhou Gan, Xin Hu, Rulin Jia,[...]. Nat Med 2016
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5
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene.
B Sadlack, H Merz, H Schorle, A Schimpl, A C Feller, I Horak. Cell 1993
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5
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.