A citation-based method for searching scientific literature

Jared R Mayers, Margaret E Torrence, Laura V Danai, Thales Papagiannakopoulos, Shawn M Davidson, Matthew R Bauer, Allison N Lau, Brian W Ji, Purushottam D Dixit, Aaron M Hosios, Alexander Muir, Christopher R Chin, Elizaveta Freinkman, Tyler Jacks, Brian M Wolpin, Dennis Vitkup, Matthew G Vander Heiden. Science 2016
Times Cited: 311







List of co-cited articles
1438 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.
Martje Tönjes, Sebastian Barbus, Yoon Jung Park, Wei Wang, Magdalena Schlotter, Anders M Lindroth, Sabrina V Pleier, Alfa H C Bai, Daniela Karra, Rosario M Piro,[...]. Nat Med 2013
286
24

Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.
Shawn M Davidson, Thales Papagiannakopoulos, Benjamin A Olenchock, Julia E Heyman, Mark A Keibler, Alba Luengo, Matthew R Bauer, Abhishek K Jha, James P O'Brien, Kerry A Pierce,[...]. Cell Metab 2016
443
23

The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type.
Mariia O Yuneva, Teresa W M Fan, Thaddeus D Allen, Richard M Higashi, Dana V Ferraris, Takashi Tsukamoto, José M Matés, Francisco J Alonso, Chunmei Wang, Youngho Seo,[...]. Cell Metab 2012
428
22

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
22

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
Jaekyoung Son, Costas A Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M Perera, Cristina R Ferrone, Edouard Mullarky, Ng Shyh-Chang,[...]. Nature 2013
22

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
21

Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Oliver D K Maddocks, Dimitris Athineos, Eric C Cheung, Pearl Lee, Tong Zhang, Niels J F van den Broek, Gillian M Mackay, Christiaan F Labuschagne, David Gay, Flore Kruiswijk,[...]. Nature 2017
248
20

Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia.
Ayuna Hattori, Makoto Tsunoda, Takaaki Konuma, Masayuki Kobayashi, Tamas Nagy, John Glushka, Fariba Tayyari, Daniel McSkimming, Natarajan Kannan, Arinobu Tojo,[...]. Nature 2017
171
19

Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development.
Jared R Mayers, Chen Wu, Clary B Clish, Peter Kraft, Margaret E Torrence, Brian P Fiske, Chen Yuan, Ying Bao, Mary K Townsend, Shelley S Tworoger,[...]. Nat Med 2014
361
19

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Haoqiang Ying, Alec C Kimmelman, Costas A Lyssiotis, Sujun Hua, Gerald C Chu, Eliot Fletcher-Sananikone, Jason W Locasale, Jaekyoung Son, Hailei Zhang, Jonathan L Coloff,[...]. Cell 2012
19

Metabolic Heterogeneity in Human Lung Tumors.
Christopher T Hensley, Brandon Faubert, Qing Yuan, Naama Lev-Cohain, Eunsook Jin, Jiyeon Kim, Lei Jiang, Bookyung Ko, Rachael Skelton, Laurin Loudat,[...]. Cell 2016
579
17

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.
Cristovão M Sousa, Douglas E Biancur, Xiaoxu Wang, Christopher J Halbrook, Mara H Sherman, Li Zhang, Daniel Kremer, Rosa F Hwang, Agnes K Witkiewicz, Haoqiang Ying,[...]. Nature 2016
558
16

BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma.
Jin-Tao Li, Miao Yin, Di Wang, Jian Wang, Ming-Zhu Lei, Ye Zhang, Ying Liu, Lei Zhang, Shao-Wu Zou, Li-Peng Hu,[...]. Nat Cell Biol 2020
47
34

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
16

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
Cosimo Commisso, Shawn M Davidson, Rengin G Soydaner-Azeloglu, Seth J Parker, Jurre J Kamphorst, Sean Hackett, Elda Grabocka, Michel Nofal, Jeffrey A Drebin, Craig B Thompson,[...]. Nature 2013
929
16

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
16

Lactate Metabolism in Human Lung Tumors.
Brandon Faubert, Kevin Y Li, Ling Cai, Christopher T Hensley, Jiyeon Kim, Lauren G Zacharias, Chendong Yang, Quyen N Do, Sarah Doucette, Daniel Burguete,[...]. Cell 2017
548
15

Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability.
Mark R Sullivan, Laura V Danai, Caroline A Lewis, Sze Ham Chan, Dan Y Gui, Tenzin Kunchok, Emily A Dennstedt, Matthew G Vander Heiden, Alexander Muir. Elife 2019
167
14

Understanding the Intersections between Metabolism and Cancer Biology.
Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
978
14

On the origin of cancer cells.
O WARBURG. Science 1956
14

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Richard Possemato, Kevin M Marks, Yoav D Shaul, Michael E Pacold, Dohoon Kim, Kıvanç Birsoy, Shalini Sethumadhavan, Hin-Koon Woo, Hyun G Jang, Abhishek K Jha,[...]. Nature 2011
13

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion.
Robert D Leone, Liang Zhao, Judson M Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L Arwood, Ian A Bettencourt, Chirag H Patel, Jiayu Wen,[...]. Science 2019
299
13

Glucose feeds the TCA cycle via circulating lactate.
Sheng Hui, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, Tannishtha Reya, Le Zhan, Jessie Yanxiang Guo,[...]. Nature 2017
590
13

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
Jason W Locasale, Alexandra R Grassian, Tamar Melman, Costas A Lyssiotis, Katherine R Mattaini, Adam J Bass, Gregory Heffron, Christian M Metallo, Taru Muranen, Hadar Sharfi,[...]. Nat Genet 2011
723
13

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
13

Branched-chain amino acid metabolism in cancer.
Elitsa A Ananieva, Adam C Wilkinson. Curr Opin Clin Nutr Metab Care 2018
136
13

Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein.
Jurre J Kamphorst, Michel Nofal, Cosimo Commisso, Sean R Hackett, Wenyun Lu, Elda Grabocka, Matthew G Vander Heiden, George Miller, Jeffrey A Drebin, Dafna Bar-Sagi,[...]. Cancer Res 2015
438
12

Targeting Metabolism for Cancer Therapy.
Alba Luengo, Dan Y Gui, Matthew G Vander Heiden. Cell Chem Biol 2017
397
12

BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation.
Simon Raffel, Mattia Falcone, Niclas Kneisel, Jenny Hansson, Wei Wang, Christoph Lutz, Lars Bullinger, Gernot Poschet, Yannic Nonnenmacher, Andrea Barnert,[...]. Nature 2017
160
11

Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.
Rodrigo Romero, Volkan I Sayin, Shawn M Davidson, Matthew R Bauer, Simranjit X Singh, Sarah E LeBoeuf, Triantafyllia R Karakousi, Donald C Ellis, Arjun Bhutkar, Francisco J Sánchez-Rivera,[...]. Nat Med 2017
289
11

Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer.
Sharanya Sivanand, Matthew G Vander Heiden. Cancer Cell 2020
93
11

Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression.
Russell E Ericksen, Siew Lan Lim, Eoin McDonnell, Wai Ho Shuen, Maya Vadiveloo, Phillip J White, Zhaobing Ding, Royston Kwok, Philip Lee, George K Radda,[...]. Cell Metab 2019
68
16

Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting.
Mark R Sullivan, Katherine R Mattaini, Emily A Dennstedt, Anna A Nguyen, Sharanya Sivanand, Montana F Reilly, Katrina Meeth, Alexander Muir, Alicia M Darnell, Marcus W Bosenberg,[...]. Cell Metab 2019
97
10

Metabolic reprogramming and cancer progression.
Brandon Faubert, Ashley Solmonson, Ralph J DeBerardinis. Science 2020
368
10

Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions.
Orianne Olivares, Jared R Mayers, Victoire Gouirand, Margaret E Torrence, Tristan Gicquel, Laurence Borge, Sophie Lac, Julie Roques, Marie-Noëlle Lavaut, Patrice Berthezène,[...]. Nat Commun 2017
172
10

Heterogeneity of tumor-induced gene expression changes in the human metabolic network.
Jie Hu, Jason W Locasale, Jason H Bielas, Jacintha O'Sullivan, Kieran Sheahan, Lewis C Cantley, Matthew G Vander Heiden, Dennis Vitkup. Nat Biotechnol 2013
267
10

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism.
Douglas E Biancur, Joao A Paulo, Beata Małachowska, Maria Quiles Del Rey, Cristovão M Sousa, Xiaoxu Wang, Albert S W Sohn, Gerald C Chu, Steven P Gygi, J Wade Harper,[...]. Nat Commun 2017
144
10

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
David R Wise, Ralph J DeBerardinis, Anthony Mancuso, Nabil Sayed, Xiao-Yong Zhang, Harla K Pfeiffer, Ilana Nissim, Evgueni Daikhin, Marc Yudkoff, Steven B McMahon,[...]. Proc Natl Acad Sci U S A 2008
10


Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.
Saverio Tardito, Anaïs Oudin, Shafiq U Ahmed, Fred Fack, Olivier Keunen, Liang Zheng, Hrvoje Miletic, Per Øystein Sakariassen, Adam Weinstock, Allon Wagner,[...]. Nat Cell Biol 2015
299
10

Branched-chain amino acids sustain pancreatic cancer growth by regulating lipid metabolism.
Ji Hyeon Lee, Young-Ra Cho, Ji Hye Kim, Jongwook Kim, Hae Yun Nam, Seong Who Kim, Jaekyoung Son. Exp Mol Med 2019
35
28

THE METABOLISM OF TUMORS IN THE BODY.
O Warburg, F Wind, E Negelein. J Gen Physiol 1927
9

Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.
Jason R Cantor, Monther Abu-Remaileh, Naama Kanarek, Elizaveta Freinkman, Xin Gao, Abner Louissaint, Caroline A Lewis, David M Sabatini. Cell 2017
203
9

Dietary methionine influences therapy in mouse cancer models and alters human metabolism.
Xia Gao, Sydney M Sanderson, Ziwei Dai, Michael A Reid, Daniel E Cooper, Min Lu, John P Richie, Amy Ciccarella, Ana Calcagnotto, Peter G Mikhael,[...]. Nature 2019
208
9

Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition.
Bryan Ngo, Eugenie Kim, Victoria Osorio-Vasquez, Sophia Doll, Sophia Bustraan, Roger J Liang, Alba Luengo, Shawn M Davidson, Ahmed Ali, Gino B Ferraro,[...]. Cancer Discov 2020
65
13

Metabolic Interactions in the Tumor Microenvironment.
Costas A Lyssiotis, Alec C Kimmelman. Trends Cell Biol 2017
355
9

Asparagine bioavailability governs metastasis in a model of breast cancer.
Simon R V Knott, Elvin Wagenblast, Showkhin Khan, Sun Y Kim, Mar Soto, Michel Wagner, Marc-Olivier Turgeon, Lisa Fish, Nicolas Erard, Annika L Gable,[...]. Nature 2018
218
9

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.
Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang, Yun-Sil Lee, Kayoko Kita, Takafumi Ochi, Karen I Zeller, Angelo M De Marzo, Jennifer E Van Eyk, Joshua T Mendell,[...]. Nature 2009
9

Amino acids in cancer.
Elizabeth L Lieu, Tu Nguyen, Shawn Rhyne, Jiyeon Kim. Exp Mol Med 2020
157
9

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.
Yan Xiang, Zachary E Stine, Jinsong Xia, Yunqi Lu, Roddy S O'Connor, Brian J Altman, Annie L Hsieh, Arvin M Gouw, Ajit G Thomas, Ping Gao,[...]. J Clin Invest 2015
242
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.