Megan M Kaneda, Karen S Messer, Natacha Ralainirina, Hongying Li, Christopher J Leem, Sara Gorjestani, Gyunghwi Woo, Abraham V Nguyen, Camila C Figueiredo, Philippe Foubert, Michael C Schmid, Melissa Pink, David G Winkler, Matthew Rausch, Vito J Palombella, Jeffery Kutok, Karen McGovern, Kelly A Frazer, Xuefeng Wu, Michael Karin, Roman Sasik, Ezra E W Cohen, Judith A Varner. Nature 2016
Times Cited: 601
Times Cited: 601
Times Cited
Times Co-cited
Similarity
Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells.
Olivier De Henau, Matthew Rausch, David Winkler, Luis Felipe Campesato, Cailian Liu, Daniel Hirschhorn Cymerman, Sadna Budhu, Arnab Ghosh, Melissa Pink, Jeremy Tchaicha,[...]. Nature 2016
Olivier De Henau, Matthew Rausch, David Winkler, Luis Felipe Campesato, Cailian Liu, Daniel Hirschhorn Cymerman, Sadna Budhu, Arnab Ghosh, Melissa Pink, Jeremy Tchaicha,[...]. Nature 2016
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Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages.
Jennifer L Guerriero, Alaba Sotayo, Holly E Ponichtera, Jessica A Castrillon, Alexandra L Pourzia, Sara Schad, Shawn F Johnson, Ruben D Carrasco, Suzan Lazo, Roderick T Bronson,[...]. Nature 2017
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Tumour-associated macrophages as treatment targets in oncology.
Alberto Mantovani, Federica Marchesi, Alberto Malesci, Luigi Laghi, Paola Allavena. Nat Rev Clin Oncol 2017
Alberto Mantovani, Federica Marchesi, Alberto Malesci, Luigi Laghi, Paola Allavena. Nat Rev Clin Oncol 2017
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Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.
Megan M Kaneda, Paola Cappello, Abraham V Nguyen, Natacha Ralainirina, Chanae R Hardamon, Philippe Foubert, Michael C Schmid, Ping Sun, Evangeline Mose, Michael Bouvet,[...]. Cancer Discov 2016
Megan M Kaneda, Paola Cappello, Abraham V Nguyen, Natacha Ralainirina, Chanae R Hardamon, Philippe Foubert, Michael C Schmid, Ping Sun, Evangeline Mose, Michael Bouvet,[...]. Cancer Discov 2016
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Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
Oscar R Colegio, Ngoc-Quynh Chu, Alison L Szabo, Thach Chu, Anne Marie Rhebergen, Vikram Jairam, Nika Cyrus, Carolyn E Brokowski, Stephanie C Eisenbarth, Gillian M Phillips,[...]. Nature 2014
Oscar R Colegio, Ngoc-Quynh Chu, Alison L Szabo, Thach Chu, Anne Marie Rhebergen, Vikram Jairam, Nika Cyrus, Carolyn E Brokowski, Stephanie C Eisenbarth, Gillian M Phillips,[...]. Nature 2014
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Macrophages as regulators of tumour immunity and immunotherapy.
David G DeNardo, Brian Ruffell. Nat Rev Immunol 2019
David G DeNardo, Brian Ruffell. Nat Rev Immunol 2019
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Tumor-associated macrophages: from mechanisms to therapy.
Roy Noy, Jeffrey W Pollard. Immunity 2014
Roy Noy, Jeffrey W Pollard. Immunity 2014
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Targeting macrophages: therapeutic approaches in cancer.
Luca Cassetta, Jeffrey W Pollard. Nat Rev Drug Discov 2018
Luca Cassetta, Jeffrey W Pollard. Nat Rev Drug Discov 2018
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CSF-1R inhibition alters macrophage polarization and blocks glioma progression.
Stephanie M Pyonteck, Leila Akkari, Alberto J Schuhmacher, Robert L Bowman, Lisa Sevenich, Daniela F Quail, Oakley C Olson, Marsha L Quick, Jason T Huse, Virginia Teijeiro,[...]. Nat Med 2013
Stephanie M Pyonteck, Leila Akkari, Alberto J Schuhmacher, Robert L Bowman, Lisa Sevenich, Daniela F Quail, Oakley C Olson, Marsha L Quick, Jason T Huse, Virginia Teijeiro,[...]. Nat Med 2013
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Macrophage diversity enhances tumor progression and metastasis.
Bin-Zhi Qian, Jeffrey W Pollard. Cell 2010
Bin-Zhi Qian, Jeffrey W Pollard. Cell 2010
17
CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans.
Gregory L Beatty, Elena G Chiorean, Matthew P Fishman, Babak Saboury, Ursina R Teitelbaum, Weijing Sun, Richard D Huhn, Wenru Song, Dongguang Li, Leslie L Sharp,[...]. Science 2011
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Macrophage activation and polarization: nomenclature and experimental guidelines.
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CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models.
Yu Zhu, Brett L Knolhoff, Melissa A Meyer, Timothy M Nywening, Brian L West, Jingqin Luo, Andrea Wang-Gillam, S Peter Goedegebuure, David C Linehan, David G DeNardo. Cancer Res 2014
Yu Zhu, Brett L Knolhoff, Melissa A Meyer, Timothy M Nywening, Brian L West, Jingqin Luo, Andrea Wang-Gillam, S Peter Goedegebuure, David C Linehan, David G DeNardo. Cancer Res 2014
15
Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial.
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15
Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression.
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14
Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy.
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Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy.
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The cellular and molecular origin of tumor-associated macrophages.
Ruth A Franklin, Will Liao, Abira Sarkar, Myoungjoo V Kim, Michael R Bivona, Kang Liu, Eric G Pamer, Ming O Li. Science 2014
Ruth A Franklin, Will Liao, Abira Sarkar, Myoungjoo V Kim, Michael R Bivona, Kang Liu, Eric G Pamer, Ming O Li. Science 2014
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CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis.
Bin-Zhi Qian, Jiufeng Li, Hui Zhang, Takanori Kitamura, Jinghang Zhang, Liam R Campion, Elizabeth A Kaiser, Linda A Snyder, Jeffrey W Pollard. Nature 2011
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Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis.
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Human chimeric antigen receptor macrophages for cancer immunotherapy.
Michael Klichinsky, Marco Ruella, Olga Shestova, Xueqing Maggie Lu, Andrew Best, Martha Zeeman, Maggie Schmierer, Konrad Gabrusiewicz, Nicholas R Anderson, Nicholas E Petty,[...]. Nat Biotechnol 2020
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13
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.
Sydney R Gordon, Roy L Maute, Ben W Dulken, Gregor Hutter, Benson M George, Melissa N McCracken, Rohit Gupta, Jonathan M Tsai, Rahul Sinha, Daniel Corey,[...]. Nature 2017
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Targeting Tumor-Associated Macrophages in Cancer.
Paulina Pathria, Tiani L Louis, Judith A Varner. Trends Immunol 2019
Paulina Pathria, Tiani L Louis, Judith A Varner. Trends Immunol 2019
12
CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin's Lymphoma.
Ranjana Advani, Ian Flinn, Leslie Popplewell, Andres Forero, Nancy L Bartlett, Nilanjan Ghosh, Justin Kline, Mark Roschewski, Ann LaCasce, Graham P Collins,[...]. N Engl J Med 2018
Ranjana Advani, Ian Flinn, Leslie Popplewell, Andres Forero, Nancy L Bartlett, Nilanjan Ghosh, Justin Kline, Mark Roschewski, Ann LaCasce, Graham P Collins,[...]. N Engl J Med 2018
11
11
Role of macrophage targeting in the antitumor activity of trabectedin.
Giovanni Germano, Roberta Frapolli, Cristina Belgiovine, Achille Anselmo, Samantha Pesce, Manuela Liguori, Eugenio Erba, Sarah Uboldi, Massimo Zucchetti, Fabio Pasqualini,[...]. Cancer Cell 2013
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11
11
Macrophage plasticity and polarization: in vivo veritas.
Antonio Sica, Alberto Mantovani. J Clin Invest 2012
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Macrophages and therapeutic resistance in cancer.
Brian Ruffell, Lisa M Coussens. Cancer Cell 2015
Brian Ruffell, Lisa M Coussens. Cancer Cell 2015
10
PD-1 blockade induces responses by inhibiting adaptive immune resistance.
Paul C Tumeh, Christina L Harview, Jennifer H Yearley, I Peter Shintaku, Emma J M Taylor, Lidia Robert, Bartosz Chmielowski, Marko Spasic, Gina Henry, Voicu Ciobanu,[...]. Nature 2014
Paul C Tumeh, Christina L Harview, Jennifer H Yearley, I Peter Shintaku, Emma J M Taylor, Lidia Robert, Bartosz Chmielowski, Marko Spasic, Gina Henry, Voicu Ciobanu,[...]. Nature 2014
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The PI3K Pathway in Human Disease.
David A Fruman, Honyin Chiu, Benjamin D Hopkins, Shubha Bagrodia, Lewis C Cantley, Robert T Abraham. Cell 2017
David A Fruman, Honyin Chiu, Benjamin D Hopkins, Shubha Bagrodia, Lewis C Cantley, Robert T Abraham. Cell 2017
10
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Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy.
David G DeNardo, Donal J Brennan, Elton Rexhepaj, Brian Ruffell, Stephen L Shiao, Stephen F Madden, William M Gallagher, Nikhil Wadhwani, Scott D Keil, Sharfaa A Junaid,[...]. Cancer Discov 2011
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9
Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy.
Felix Klug, Hridayesh Prakash, Peter E Huber, Tobias Seibel, Noemi Bender, Niels Halama, Christina Pfirschke, Ralf Holger Voss, Carmen Timke, Ludmila Umansky,[...]. Cancer Cell 2013
Felix Klug, Hridayesh Prakash, Peter E Huber, Tobias Seibel, Noemi Bender, Niels Halama, Christina Pfirschke, Ralf Holger Voss, Carmen Timke, Ludmila Umansky,[...]. Cancer Cell 2013
9
Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate.
Catherine A Evans, Tao Liu, André Lescarbeau, Somarajan J Nair, Louis Grenier, Johan A Pradeilles, Quentin Glenadel, Thomas Tibbitts, Ann M Rowley, Jonathan P DiNitto,[...]. ACS Med Chem Lett 2016
Catherine A Evans, Tao Liu, André Lescarbeau, Somarajan J Nair, Louis Grenier, Johan A Pradeilles, Quentin Glenadel, Thomas Tibbitts, Ann M Rowley, Jonathan P DiNitto,[...]. ACS Med Chem Lett 2016
11
The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas.
Daniela F Quail, Robert L Bowman, Leila Akkari, Marsha L Quick, Alberto J Schuhmacher, Jason T Huse, Eric C Holland, James C Sutton, Johanna A Joyce. Science 2016
Daniela F Quail, Robert L Bowman, Leila Akkari, Marsha L Quick, Alberto J Schuhmacher, Jason T Huse, Eric C Holland, James C Sutton, Johanna A Joyce. Science 2016
9
The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment.
Vinit Kumar, Sima Patel, Evgenii Tcyganov, Dmitry I Gabrilovich. Trends Immunol 2016
Vinit Kumar, Sima Patel, Evgenii Tcyganov, Dmitry I Gabrilovich. Trends Immunol 2016
9
T cell-induced CSF1 promotes melanoma resistance to PD1 blockade.
Natalie J Neubert, Martina Schmittnaegel, Natacha Bordry, Sina Nassiri, Noémie Wald, Christophe Martignier, Laure Tillé, Krisztian Homicsko, William Damsky, Hélène Maby-El Hajjami,[...]. Sci Transl Med 2018
Natalie J Neubert, Martina Schmittnaegel, Natacha Bordry, Sina Nassiri, Noémie Wald, Christophe Martignier, Laure Tillé, Krisztian Homicsko, William Damsky, Hélène Maby-El Hajjami,[...]. Sci Transl Med 2018
8
Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma.
Mark P Chao, Ash A Alizadeh, Chad Tang, June H Myklebust, Bindu Varghese, Saar Gill, Max Jan, Adriel C Cha, Charles K Chan, Brent T Tan,[...]. Cell 2010
Mark P Chao, Ash A Alizadeh, Chad Tang, June H Myklebust, Bindu Varghese, Saar Gill, Max Jan, Adriel C Cha, Charles K Chan, Brent T Tan,[...]. Cell 2010
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Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy.
Padmanee Sharma, Siwen Hu-Lieskovan, Jennifer A Wargo, Antoni Ribas. Cell 2017
Padmanee Sharma, Siwen Hu-Lieskovan, Jennifer A Wargo, Antoni Ribas. Cell 2017
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Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy.
Michael A Cannarile, Martin Weisser, Wolfgang Jacob, Anna-Maria Jegg, Carola H Ries, Dominik Rüttinger. J Immunother Cancer 2017
Michael A Cannarile, Martin Weisser, Wolfgang Jacob, Anna-Maria Jegg, Carola H Ries, Dominik Rüttinger. J Immunother Cancer 2017
8
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.
Stephen B Willingham, Jens-Peter Volkmer, Andrew J Gentles, Debashis Sahoo, Piero Dalerba, Siddhartha S Mitra, Jian Wang, Humberto Contreras-Trujillo, Robin Martin, Justin D Cohen,[...]. Proc Natl Acad Sci U S A 2012
Stephen B Willingham, Jens-Peter Volkmer, Andrew J Gentles, Debashis Sahoo, Piero Dalerba, Siddhartha S Mitra, Jian Wang, Humberto Contreras-Trujillo, Robin Martin, Justin D Cohen,[...]. Proc Natl Acad Sci U S A 2012
8
Coordinated regulation of myeloid cells by tumours.
Dmitry I Gabrilovich, Suzanne Ostrand-Rosenberg, Vincenzo Bronte. Nat Rev Immunol 2012
Dmitry I Gabrilovich, Suzanne Ostrand-Rosenberg, Vincenzo Bronte. Nat Rev Immunol 2012
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PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting.
Lauren M Thorpe, Haluk Yuzugullu, Jean J Zhao. Nat Rev Cancer 2015
Lauren M Thorpe, Haluk Yuzugullu, Jean J Zhao. Nat Rev Cancer 2015
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Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival.
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8
Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species.
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8
PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation.
Muhammad Zaeem Noman, Giacomo Desantis, Bassam Janji, Meriem Hasmim, Saoussen Karray, Philippe Dessen, Vincenzo Bronte, Salem Chouaib. J Exp Med 2014
Muhammad Zaeem Noman, Giacomo Desantis, Bassam Janji, Meriem Hasmim, Saoussen Karray, Philippe Dessen, Vincenzo Bronte, Salem Chouaib. J Exp Med 2014
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The prognostic landscape of genes and infiltrating immune cells across human cancers.
Andrew J Gentles, Aaron M Newman, Chih Long Liu, Scott V Bratman, Weiguo Feng, Dongkyoon Kim, Viswam S Nair, Yue Xu, Amanda Khuong, Chuong D Hoang,[...]. Nat Med 2015
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Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis.
Laura Bonapace, Marie-May Coissieux, Jeffrey Wyckoff, Kirsten D Mertz, Zsuzsanna Varga, Tobias Junt, Mohamed Bentires-Alj. Nature 2014
Laura Bonapace, Marie-May Coissieux, Jeffrey Wyckoff, Kirsten D Mertz, Zsuzsanna Varga, Tobias Junt, Mohamed Bentires-Alj. Nature 2014
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Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm.
Subhra K Biswas, Alberto Mantovani. Nat Immunol 2010
Subhra K Biswas, Alberto Mantovani. Nat Immunol 2010
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.