Gad Abraham, Aki S Havulinna, Oneil G Bhalala, Sean G Byars, Alysha M De Livera, Laxman Yetukuri, Emmi Tikkanen, Markus Perola, Heribert Schunkert, Eric J Sijbrands, Aarno Palotie, Nilesh J Samani, Veikko Salomaa, Samuli Ripatti, Michael Inouye. Eur Heart J 2016
Times Cited: 154
Times Cited: 154
Times Cited
Times Co-cited
Similarity
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations.
Amit V Khera, Mark Chaffin, Krishna G Aragam, Mary E Haas, Carolina Roselli, Seung Hoan Choi, Pradeep Natarajan, Eric S Lander, Steven A Lubitz, Patrick T Ellinor,[...]. Nat Genet 2018
Amit V Khera, Mark Chaffin, Krishna G Aragam, Mary E Haas, Carolina Roselli, Seung Hoan Choi, Pradeep Natarajan, Eric S Lander, Steven A Lubitz, Patrick T Ellinor,[...]. Nat Genet 2018
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Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention.
Michael Inouye, Gad Abraham, Christopher P Nelson, Angela M Wood, Michael J Sweeting, Frank Dudbridge, Florence Y Lai, Stephen Kaptoge, Marta Brozynska, Tingting Wang,[...]. J Am Coll Cardiol 2018
Michael Inouye, Gad Abraham, Christopher P Nelson, Angela M Wood, Michael J Sweeting, Frank Dudbridge, Florence Y Lai, Stephen Kaptoge, Marta Brozynska, Tingting Wang,[...]. J Am Coll Cardiol 2018
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Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease.
Amit V Khera, Connor A Emdin, Isabel Drake, Pradeep Natarajan, Alexander G Bick, Nancy R Cook, Daniel I Chasman, Usman Baber, Roxana Mehran, Daniel J Rader,[...]. N Engl J Med 2016
Amit V Khera, Connor A Emdin, Isabel Drake, Pradeep Natarajan, Alexander G Bick, Nancy R Cook, Daniel I Chasman, Usman Baber, Roxana Mehran, Daniel J Rader,[...]. N Engl J Med 2016
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Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.
J L Mega, N O Stitziel, J G Smith, D I Chasman, M Caulfield, J J Devlin, F Nordio, C Hyde, C P Cannon, F Sacks,[...]. Lancet 2015
J L Mega, N O Stitziel, J G Smith, D I Chasman, M Caulfield, J J Devlin, F Nordio, C Hyde, C P Cannon, F Sacks,[...]. Lancet 2015
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A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses.
Samuli Ripatti, Emmi Tikkanen, Marju Orho-Melander, Aki S Havulinna, Kaisa Silander, Amitabh Sharma, Candace Guiducci, Markus Perola, Antti Jula, Juha Sinisalo,[...]. Lancet 2010
Samuli Ripatti, Emmi Tikkanen, Marju Orho-Melander, Aki S Havulinna, Kaisa Silander, Amitabh Sharma, Candace Guiducci, Markus Perola, Antti Jula, Juha Sinisalo,[...]. Lancet 2010
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Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting.
Pradeep Natarajan, Robin Young, Nathan O Stitziel, Sandosh Padmanabhan, Usman Baber, Roxana Mehran, Samantha Sartori, Valentin Fuster, Dermot F Reilly, Adam Butterworth,[...]. Circulation 2017
Pradeep Natarajan, Robin Young, Nathan O Stitziel, Sandosh Padmanabhan, Usman Baber, Roxana Mehran, Samantha Sartori, Valentin Fuster, Dermot F Reilly, Adam Butterworth,[...]. Circulation 2017
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Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history.
Hayato Tada, Olle Melander, Judy Z Louie, Joseph J Catanese, Charles M Rowland, James J Devlin, Sekar Kathiresan, Dov Shiffman. Eur Heart J 2016
Hayato Tada, Olle Melander, Judy Z Louie, Joseph J Catanese, Charles M Rowland, James J Devlin, Sekar Kathiresan, Dov Shiffman. Eur Heart J 2016
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Clinical use of current polygenic risk scores may exacerbate health disparities.
Alicia R Martin, Masahiro Kanai, Yoichiro Kamatani, Yukinori Okada, Benjamin M Neale, Mark J Daly. Nat Genet 2019
Alicia R Martin, Masahiro Kanai, Yoichiro Kamatani, Yukinori Okada, Benjamin M Neale, Mark J Daly. Nat Genet 2019
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A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
Majid Nikpay, Anuj Goel, Hong-Hee Won, Leanne M Hall, Christina Willenborg, Stavroula Kanoni, Danish Saleheen, Theodosios Kyriakou, Christopher P Nelson, Jemma C Hopewell,[...]. Nat Genet 2015
Majid Nikpay, Anuj Goel, Hong-Hee Won, Leanne M Hall, Christina Willenborg, Stavroula Kanoni, Danish Saleheen, Theodosios Kyriakou, Christopher P Nelson, Jemma C Hopewell,[...]. Nat Genet 2015
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Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease.
Jonathan D Mosley, Deepak K Gupta, Jingyi Tan, Jie Yao, Quinn S Wells, Christian M Shaffer, Suman Kundu, Cassianne Robinson-Cohen, Bruce M Psaty, Stephen S Rich,[...]. JAMA 2020
Jonathan D Mosley, Deepak K Gupta, Jingyi Tan, Jie Yao, Quinn S Wells, Christian M Shaffer, Suman Kundu, Cassianne Robinson-Cohen, Bruce M Psaty, Stephen S Rich,[...]. JAMA 2020
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Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
Bjarni J Vilhjálmsson, Jian Yang, Hilary K Finucane, Alexander Gusev, Sara Lindström, Stephan Ripke, Giulio Genovese, Po-Ru Loh, Gaurav Bhatia, Ron Do,[...]. Am J Hum Genet 2015
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Predictive Accuracy of a Polygenic Risk Score-Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease.
Joshua Elliott, Barbara Bodinier, Tom A Bond, Marc Chadeau-Hyam, Evangelos Evangelou, Karel G M Moons, Abbas Dehghan, David C Muller, Paul Elliott, Ioanna Tzoulaki. JAMA 2020
Joshua Elliott, Barbara Bodinier, Tom A Bond, Marc Chadeau-Hyam, Evangelos Evangelou, Karel G M Moons, Abbas Dehghan, David C Muller, Paul Elliott, Ioanna Tzoulaki. JAMA 2020
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Large-scale association analysis identifies new risk loci for coronary artery disease.
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The personal and clinical utility of polygenic risk scores.
Ali Torkamani, Nathan E Wineinger, Eric J Topol. Nat Rev Genet 2018
Ali Torkamani, Nathan E Wineinger, Eric J Topol. Nat Rev Genet 2018
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A common variant on chromosome 9p21 affects the risk of myocardial infarction.
Anna Helgadottir, Gudmar Thorleifsson, Andrei Manolescu, Solveig Gretarsdottir, Thorarinn Blondal, Aslaug Jonasdottir, Adalbjorg Jonasdottir, Asgeir Sigurdsson, Adam Baker, Arnar Palsson,[...]. Science 2007
Anna Helgadottir, Gudmar Thorleifsson, Andrei Manolescu, Solveig Gretarsdottir, Thorarinn Blondal, Aslaug Jonasdottir, Adalbjorg Jonasdottir, Asgeir Sigurdsson, Adam Baker, Arnar Palsson,[...]. Science 2007
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Developing and evaluating polygenic risk prediction models for stratified disease prevention.
Nilanjan Chatterjee, Jianxin Shi, Montserrat García-Closas. Nat Rev Genet 2016
Nilanjan Chatterjee, Jianxin Shi, Montserrat García-Closas. Nat Rev Genet 2016
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Predicting Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease Using a Genetic Risk Score: Results From the FOURIER Trial.
Nicholas A Marston, Frederick K Kamanu, Francesco Nordio, Yared Gurmu, Carolina Roselli, Peter S Sever, Terje R Pedersen, Anthony C Keech, Huei Wang, Armando Lira Pineda,[...]. Circulation 2020
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Second-generation PLINK: rising to the challenge of larger and richer datasets.
Christopher C Chang, Carson C Chow, Laurent Cam Tellier, Shashaank Vattikuti, Shaun M Purcell, James J Lee. Gigascience 2015
Christopher C Chang, Carson C Chow, Laurent Cam Tellier, Shashaank Vattikuti, Shaun M Purcell, James J Lee. Gigascience 2015
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Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk Estimates: Effect on Low-Density Lipoprotein Cholesterol Levels (the MI-GENES Clinical Trial).
Iftikhar J Kullo, Hayan Jouni, Erin E Austin, Sherry-Ann Brown, Teresa M Kruisselbrink, Iyad N Isseh, Raad A Haddad, Tariq S Marroush, Khader Shameer, Janet E Olson,[...]. Circulation 2016
Iftikhar J Kullo, Hayan Jouni, Erin E Austin, Sherry-Ann Brown, Teresa M Kruisselbrink, Iyad N Isseh, Raad A Haddad, Tariq S Marroush, Khader Shameer, Janet E Olson,[...]. Circulation 2016
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Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial Infarction.
Amit V Khera, Mark Chaffin, Seyedeh M Zekavat, Ryan L Collins, Carolina Roselli, Pradeep Natarajan, Judith H Lichtman, Gail D'Onofrio, Jennifer Mattera, Rachel Dreyer,[...]. Circulation 2019
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Patients With High Genome-Wide Polygenic Risk Scores for Coronary Artery Disease May Receive Greater Clinical Benefit From Alirocumab Treatment in the ODYSSEY OUTCOMES Trial.
Amy Damask, P Gabriel Steg, Gregory G Schwartz, Michael Szarek, Emil Hagström, Lina Badimon, M John Chapman, Catherine Boileau, Sotirios Tsimikas, Henry N Ginsberg,[...]. Circulation 2020
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Towards clinical utility of polygenic risk scores.
Samuel A Lambert, Gad Abraham, Michael Inouye. Hum Mol Genet 2019
Samuel A Lambert, Gad Abraham, Michael Inouye. Hum Mol Genet 2019
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2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
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Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease: prospective cohort study.
Julia Hippisley-Cox, Carol Coupland, Peter Brindle. BMJ 2017
Julia Hippisley-Cox, Carol Coupland, Peter Brindle. BMJ 2017
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Association analyses based on false discovery rate implicate new loci for coronary artery disease.
Christopher P Nelson, Anuj Goel, Adam S Butterworth, Stavroula Kanoni, Tom R Webb, Eirini Marouli, Lingyao Zeng, Ioanna Ntalla, Florence Y Lai, Jemma C Hopewell,[...]. Nat Genet 2017
Christopher P Nelson, Anuj Goel, Adam S Butterworth, Stavroula Kanoni, Tom R Webb, Eirini Marouli, Lingyao Zeng, Ioanna Ntalla, Florence Y Lai, Jemma C Hopewell,[...]. Nat Genet 2017
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A decade of genome-wide association studies for coronary artery disease: the challenges ahead.
Jeanette Erdmann, Thorsten Kessler, Loreto Munoz Venegas, Heribert Schunkert. Cardiovasc Res 2018
Jeanette Erdmann, Thorsten Kessler, Loreto Munoz Venegas, Heribert Schunkert. Cardiovasc Res 2018
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Genetic risk prediction and a 2-stage risk screening strategy for coronary heart disease.
Emmi Tikkanen, Aki S Havulinna, Aarno Palotie, Veikko Salomaa, Samuli Ripatti. Arterioscler Thromb Vasc Biol 2013
Emmi Tikkanen, Aki S Havulinna, Aarno Palotie, Veikko Salomaa, Samuli Ripatti. Arterioscler Thromb Vasc Biol 2013
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Discovery and refinement of loci associated with lipid levels.
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Genomewide association analysis of coronary artery disease.
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UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age.
Cathie Sudlow, John Gallacher, Naomi Allen, Valerie Beral, Paul Burton, John Danesh, Paul Downey, Paul Elliott, Jane Green, Martin Landray,[...]. PLoS Med 2015
Cathie Sudlow, John Gallacher, Naomi Allen, Valerie Beral, Paul Burton, John Danesh, Paul Downey, Paul Elliott, Jane Green, Martin Landray,[...]. PLoS Med 2015
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Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
Pim van der Harst, Niek Verweij. Circ Res 2018
Pim van der Harst, Niek Verweij. Circ Res 2018
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Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers.
Nina Mars, Jukka T Koskela, Pietari Ripatti, Tuomo T J Kiiskinen, Aki S Havulinna, Joni V Lindbohm, Ari Ahola-Olli, Mitja Kurki, Juha Karjalainen, Priit Palta,[...]. Nat Med 2020
Nina Mars, Jukka T Koskela, Pietari Ripatti, Tuomo T J Kiiskinen, Aki S Havulinna, Joni V Lindbohm, Ari Ahola-Olli, Mitja Kurki, Juha Karjalainen, Priit Palta,[...]. Nat Med 2020
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A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study.
George Thanassoulis, Gina M Peloso, Michael J Pencina, Udo Hoffmann, Caroline S Fox, L Adrienne Cupples, Daniel Levy, Ralph B D'Agostino, Shih-Jen Hwang, Christopher J O'Donnell. Circ Cardiovasc Genet 2012
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A common allele on chromosome 9 associated with coronary heart disease.
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Ruth McPherson, Alexander Pertsemlidis, Nihan Kavaslar, Alexandre Stewart, Robert Roberts, David R Cox, David A Hinds, Len A Pennacchio, Anne Tybjaerg-Hansen, Aaron R Folsom,[...]. Science 2007
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Mutations in PCSK9 cause autosomal dominant hypercholesterolemia.
Marianne Abifadel, Mathilde Varret, Jean-Pierre Rabès, Delphine Allard, Khadija Ouguerram, Martine Devillers, Corinne Cruaud, Suzanne Benjannet, Louise Wickham, Danièle Erlich,[...]. Nat Genet 2003
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Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.
Jonathan C Cohen, Eric Boerwinkle, Thomas H Mosley, Helen H Hobbs. N Engl J Med 2006
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The UK Biobank resource with deep phenotyping and genomic data.
Clare Bycroft, Colin Freeman, Desislava Petkova, Gavin Band, Lloyd T Elliott, Kevin Sharp, Allan Motyer, Damjan Vukcevic, Olivier Delaneau, Jared O'Connell,[...]. Nature 2018
Clare Bycroft, Colin Freeman, Desislava Petkova, Gavin Band, Lloyd T Elliott, Kevin Sharp, Allan Motyer, Damjan Vukcevic, Olivier Delaneau, Jared O'Connell,[...]. Nature 2018
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Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations.
Alicia R Martin, Christopher R Gignoux, Raymond K Walters, Genevieve L Wojcik, Benjamin M Neale, Simon Gravel, Mark J Daly, Carlos D Bustamante, Eimear E Kenny. Am J Hum Genet 2017
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10 Years of GWAS Discovery: Biology, Function, and Translation.
Peter M Visscher, Naomi R Wray, Qian Zhang, Pamela Sklar, Mark I McCarthy, Matthew A Brown, Jian Yang. Am J Hum Genet 2017
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Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups.
Ozan Dikilitas, Daniel J Schaid, Matthew L Kosel, Robert J Carroll, Christopher G Chute, Joshua A Denny, Alex Fedotov, QiPing Feng, Hakon Hakonarson, Gail P Jarvik,[...]. Am J Hum Genet 2020
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Genetics of coronary artery disease: discovery, biology and clinical translation.
Amit V Khera, Sekar Kathiresan. Nat Rev Genet 2017
Amit V Khera, Sekar Kathiresan. Nat Rev Genet 2017
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Prediction of coronary heart disease using risk factor categories.
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Polymorphisms associated with cholesterol and risk of cardiovascular events.
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An Expanded View of Complex Traits: From Polygenic to Omnigenic.
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Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.
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2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
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Associations of Combined Genetic and Lifestyle Risks With Incident Cardiovascular Disease and Diabetes in the UK Biobank Study.
M Abdullah Said, Niek Verweij, Pim van der Harst. JAMA Cardiol 2018
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Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.
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Multilocus genetic risk scores for coronary heart disease prediction.
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Hyperlipidemia in early adulthood increases long-term risk of coronary heart disease.
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8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.