A citation-based method for searching scientific literature

X Shawn Liu, Hao Wu, Xiong Ji, Yonatan Stelzer, Xuebing Wu, Szymon Czauderna, Jian Shu, Daniel Dadon, Richard A Young, Rudolf Jaenisch. Cell 2016
Times Cited: 549







List of co-cited articles
1063 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.
Isaac B Hilton, Anthony M D'Ippolito, Christopher M Vockley, Pratiksha I Thakore, Gregory E Crawford, Timothy E Reddy, Charles A Gersbach. Nat Biotechnol 2015
893
34

A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
28

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.
Luke A Gilbert, Matthew H Larson, Leonardo Morsut, Zairan Liu, Gloria A Brar, Sandra E Torres, Noam Stern-Ginossar, Onn Brandman, Evan H Whitehead, Jennifer A Doudna,[...]. Cell 2013
28

Repurposing the CRISPR-Cas9 system for targeted DNA methylation.
Aleksandar Vojta, Paula Dobrinić, Vanja Tadić, Luka Bočkor, Petra Korać, Boris Julg, Marija Klasić, Vlatka Zoldoš. Nucleic Acids Res 2016
358
24

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.
Silvana Konermann, Mark D Brigham, Alexandro E Trevino, Julia Joung, Omar O Abudayyeh, Clea Barcena, Patrick D Hsu, Naomi Habib, Jonathan S Gootenberg, Hiroshi Nishimasu,[...]. Nature 2015
23

Functional annotation of native enhancers with a Cas9-histone demethylase fusion.
Nicola A Kearns, Hannah Pham, Barbara Tabak, Ryan M Genga, Noah J Silverstein, Manuel Garber, René Maehr. Nat Methods 2015
367
20

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.
Lei S Qi, Matthew H Larson, Luke A Gilbert, Jennifer A Doudna, Jonathan S Weissman, Adam P Arkin, Wendell A Lim. Cell 2013
20

A CRISPR-based approach for targeted DNA demethylation.
Xingxing Xu, Yonghui Tao, Xiaobo Gao, Lei Zhang, Xufang Li, Weiguo Zou, Kangcheng Ruan, Feng Wang, Guo-Liang Xu, Ronggui Hu. Cell Discov 2016
189
20

Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions.
Sumiyo Morita, Hirofumi Noguchi, Takuro Horii, Kazuhiko Nakabayashi, Mika Kimura, Kohji Okamura, Atsuhiko Sakai, Hideyuki Nakashima, Kenichiro Hata, Kinichi Nakashima,[...]. Nat Biotechnol 2016
213
19

CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter.
Samrat Roy Choudhury, Yi Cui, Katarzyna Lubecka, Barbara Stefanska, Joseph Irudayaraj. Oncotarget 2016
140
18

Highly efficient Cas9-mediated transcriptional programming.
Alejandro Chavez, Jonathan Scheiman, Suhani Vora, Benjamin W Pruitt, Marcelle Tuttle, Eswar P R Iyer, Shuailiang Lin, Samira Kiani, Christopher D Guzman, Daniel J Wiegand,[...]. Nat Methods 2015
659
17

Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing.
Angelo Amabile, Alessandro Migliara, Paola Capasso, Mauro Biffi, Davide Cittaro, Luigi Naldini, Angelo Lombardo. Cell 2016
189
16

CRISPR RNA-guided activation of endogenous human genes.
Morgan L Maeder, Samantha J Linder, Vincent M Cascio, Yanfang Fu, Quan H Ho, J Keith Joung. Nat Methods 2013
643
16

Multiplex genome engineering using CRISPR/Cas systems.
Le Cong, F Ann Ran, David Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, Patrick D Hsu, Xuebing Wu, Wenyan Jiang, Luciano A Marraffini,[...]. Science 2013
16

Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation.
James I McDonald, Hamza Celik, Lisa E Rois, Gregory Fishberger, Tolison Fowler, Ryan Rees, Ashley Kramer, Andrew Martens, John R Edwards, Grant A Challen. Biol Open 2016
146
15

A protein-tagging system for signal amplification in gene expression and fluorescence imaging.
Marvin E Tanenbaum, Luke A Gilbert, Lei S Qi, Jonathan S Weissman, Ronald D Vale. Cell 2014
672
15

Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene.
X Shawn Liu, Hao Wu, Marine Krzisch, Xuebing Wu, John Graef, Julien Muffat, Denes Hnisz, Charles H Li, Bingbing Yuan, Chuanyun Xu,[...]. Cell 2018
177
15

Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein.
Yong Lei, Xiaotian Zhang, Jianzhong Su, Mira Jeong, Michael C Gundry, Yung-Hsin Huang, Yubin Zhou, Wei Li, Margaret A Goodell. Nat Commun 2017
86
16

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.
Luke A Gilbert, Max A Horlbeck, Britt Adamson, Jacqueline E Villalta, Yuwen Chen, Evan H Whitehead, Carla Guimaraes, Barbara Panning, Hidde L Ploegh, Michael C Bassik,[...]. Cell 2014
14

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.
Pratiksha I Thakore, Anthony M D'Ippolito, Lingyun Song, Alexias Safi, Nishkala K Shivakumar, Ami M Kabadi, Timothy E Reddy, Gregory E Crawford, Charles A Gersbach. Nat Methods 2015
417
14

Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner.
David Cano-Rodriguez, Rutger A F Gjaltema, Laura J Jilderda, Pytrick Jellema, Jelleke Dokter-Fokkens, Marcel H J Ruiters, Marianne G Rots. Nat Commun 2016
113
13

Locus-specific histone deacetylation using a synthetic CRISPR-Cas9-based HDAC.
Deborah Y Kwon, Ying-Tao Zhao, Janine M Lamonica, Zhaolan Zhou. Nat Commun 2017
95
13

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
13

RNA-guided human genome engineering via Cas9.
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
12

DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A.
Yung-Hsin Huang, Jianzhong Su, Yong Lei, Lorenzo Brunetti, Michael C Gundry, Xiaotian Zhang, Mira Jeong, Wei Li, Margaret A Goodell. Genome Biol 2017
83
14

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.
Peter Stepper, Goran Kungulovski, Renata Z Jurkowska, Tamir Chandra, Felix Krueger, Richard Reinhardt, Wolf Reik, Albert Jeltsch, Tomasz P Jurkowski. Nucleic Acids Res 2017
110
12

Genome-wide tracking of dCas9-methyltransferase footprints.
Christina Galonska, Jocelyn Charlton, Alexandra L Mattei, Julie Donaghey, Kendell Clement, Hongcang Gu, Arman W Mohammad, Elena K Stamenova, Davide Cacchiarelli, Sven Klages,[...]. Nat Commun 2018
64
18

RNA-guided gene activation by CRISPR-Cas9-based transcription factors.
Pablo Perez-Pinera, D Dewran Kocak, Christopher M Vockley, Andrew F Adler, Ami M Kabadi, Lauren R Polstein, Pratiksha I Thakore, Katherine A Glass, David G Ousterout, Kam W Leong,[...]. Nat Methods 2013
694
12

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
12

CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency.
Navneet Matharu, Sawitree Rattanasopha, Serena Tamura, Lenka Maliskova, Yi Wang, Adelaide Bernard, Aaron Hardin, Walter L Eckalbar, Christian Vaisse, Nadav Ahituv. Science 2019
98
11

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
Johnny H Hu, Shannon M Miller, Maarten H Geurts, Weixin Tang, Liwei Chen, Ning Sun, Christina M Zeina, Xue Gao, Holly A Rees, Zhi Lin,[...]. Nature 2018
607
11

The diverse roles of DNA methylation in mammalian development and disease.
Maxim V C Greenberg, Deborah Bourc'his. Nat Rev Mol Cell Biol 2019
378
11

In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation.
Hsin-Kai Liao, Fumiyuki Hatanaka, Toshikazu Araoka, Pradeep Reddy, Min-Zu Wu, Yinghui Sui, Takayoshi Yamauchi, Masahiro Sakurai, David D O'Keefe, Estrella Núñez-Delicado,[...]. Cell 2017
196
10

A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs.
Christian Pflueger, Dennis Tan, Tessa Swain, Trung Nguyen, Jahnvi Pflueger, Christian Nefzger, Jose M Polo, Ethan Ford, Ryan Lister. Genome Res 2018
55
18

Comparison of Cas9 activators in multiple species.
Alejandro Chavez, Marcelle Tuttle, Benjamin W Pruitt, Ben Ewen-Campen, Raj Chari, Dmitry Ter-Ovanesyan, Sabina J Haque, Ryan J Cecchi, Emma J K Kowal, Joanna Buchthal,[...]. Nat Methods 2016
229
10

Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory in a context-dependent manner.
Henriette O'Geen, Sofie L Bates, Sakereh S Carter, Karly A Nisson, Julian Halmai, Kyle D Fink, Suhn K Rhie, Peggy J Farnham, David J Segal. Epigenetics Chromatin 2019
37
27

Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds.
Jesse G Zalatan, Michael E Lee, Ricardo Almeida, Luke A Gilbert, Evan H Whitehead, Marie La Russa, Jordan C Tsai, Jonathan S Weissman, John E Dueber, Lei S Qi,[...]. Cell 2015
515
10


An enhanced CRISPR repressor for targeted mammalian gene regulation.
Nan Cher Yeo, Alejandro Chavez, Alissa Lance-Byrne, Yingleong Chan, David Menn, Denitsa Milanova, Chih-Chung Kuo, Xiaoge Guo, Sumana Sharma, Angela Tung,[...]. Nat Methods 2018
123
10

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
10

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR-dCas9-activator transgenic mice.
Haibo Zhou, Junlai Liu, Changyang Zhou, Ni Gao, Zhiping Rao, He Li, Xinde Hu, Changlin Li, Xuan Yao, Xiaowen Shen,[...]. Nat Neurosci 2018
101
9

dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression.
Henriette O'Geen, Chonghua Ren, Charles M Nicolet, Andrew A Perez, Julian Halmai, Victoria M Le, Joel P Mackay, Peggy J Farnham, David J Segal. Nucleic Acids Res 2017
72
12

Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells.
Masahiro Okada, Mitsuhiro Kanamori, Kazue Someya, Hiroko Nakatsukasa, Akihiko Yoshimura. Epigenetics Chromatin 2017
59
15

Rapid and reversible epigenome editing by endogenous chromatin regulators.
Simon M G Braun, Jacob G Kirkland, Emma J Chory, Dylan Husmann, Joseph P Calarco, Gerald R Crabtree. Nat Commun 2017
74
12

Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors.
Emily A Saunderson, Peter Stepper, Jennifer J Gomm, Lily Hoa, Adrienne Morgan, Michael D Allen, J Louise Jones, John G Gribben, Tomasz P Jurkowski, Gabriella Ficz. Nat Commun 2017
45
17

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system.
Albert W Cheng, Haoyi Wang, Hui Yang, Linyu Shi, Yarden Katz, Thorold W Theunissen, Sudharshan Rangarajan, Chikdu S Shivalila, Daniel B Dadon, Rudolf Jaenisch. Cell Res 2013
452
8

Breaking the code of DNA binding specificity of TAL-type III effectors.
Jens Boch, Heidi Scholze, Sebastian Schornack, Angelika Landgraf, Simone Hahn, Sabine Kay, Thomas Lahaye, Anja Nickstadt, Ulla Bonas. Science 2009
8

In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni.
Eunji Kim, Taeyoung Koo, Sung Wook Park, Daesik Kim, Kyoungmi Kim, Hee-Yeon Cho, Dong Woo Song, Kyu Jun Lee, Min Hee Jung, Seokjoong Kim,[...]. Nat Commun 2017
271
8

Targeted DNA methylation in human cells using engineered dCas9-methyltransferases.
Tina Xiong, Glenna E Meister, Rachael E Workman, Nathaniel C Kato, Michael J Spellberg, Fulya Turker, Winston Timp, Marc Ostermeier, Carl D Novina. Sci Rep 2017
38
21

Human pluripotent reprogramming with CRISPR activators.
Jere Weltner, Diego Balboa, Shintaro Katayama, Maxim Bespalov, Kaarel Krjutškov, Eeva-Mari Jouhilahti, Ras Trokovic, Juha Kere, Timo Otonkoski. Nat Commun 2018
59
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.