A citation-based method for searching scientific literature

Ravi Amaravadi, Alec C Kimmelman, Eileen White. Genes Dev 2016
Times Cited: 435







List of co-cited articles
764 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Targeting autophagy in cancer.
Jean M Mulcahy Levy, Christina G Towers, Andrew Thorburn. Nat Rev Cancer 2017
25

Autophagy and Tumor Metabolism.
Alec C Kimmelman, Eileen White. Cell Metab 2017
426
17


The role for autophagy in cancer.
Eileen White. J Clin Invest 2015
776
14

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
13

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene.
Xueping Qu, Jie Yu, Govind Bhagat, Norihiko Furuya, Hanina Hibshoosh, Andrea Troxel, Jeffrey Rosen, Eeva-Liisa Eskelinen, Noboru Mizushima, Yoshinori Ohsumi,[...]. J Clin Invest 2003
13

Autophagy: renovation of cells and tissues.
Noboru Mizushima, Masaaki Komatsu. Cell 2011
12

Autophagy-deficient mice develop multiple liver tumors.
Akito Takamura, Masaaki Komatsu, Taichi Hara, Ayako Sakamoto, Chieko Kishi, Satoshi Waguri, Yoshinobu Eishi, Okio Hino, Keiji Tanaka, Noboru Mizushima. Genes Dev 2011
854
12

Autophagy in the pathogenesis of disease.
Beth Levine, Guido Kroemer. Cell 2008
11

Targeting Autophagy in Cancer: Recent Advances and Future Directions.
Ravi K Amaravadi, Alec C Kimmelman, Jayanta Debnath. Cancer Discov 2019
289
11


Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis.
Kurt Degenhardt, Robin Mathew, Brian Beaudoin, Kevin Bray, Diana Anderson, Guanghua Chen, Chandreyee Mukherjee, Yufang Shi, Céline Gélinas, Yongjun Fan,[...]. Cancer Cell 2006
10

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
10

Induction of autophagy and inhibition of tumorigenesis by beclin 1.
X H Liang, S Jackson, M Seaman, K Brown, B Kempkes, H Hibshoosh, B Levine. Nature 1999
10

Functions of autophagy in the tumor microenvironment and cancer metastasis.
Erin E Mowers, Marina N Sharifi, Kay F Macleod. FEBS J 2018
106
10

An overview of autophagy: morphology, mechanism, and regulation.
Katherine R Parzych, Daniel J Klionsky. Antioxid Redox Signal 2014
946
10

Targeting autophagy in cancer.
Angelique V Onorati, Matheus Dyczynski, Rani Ojha, Ravi K Amaravadi. Cancer 2018
254
10

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment.
X Sui, R Chen, Z Wang, Z Huang, N Kong, M Zhang, W Han, F Lou, J Yang, Q Zhang,[...]. Cell Death Dis 2013
773
9

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
Keisuke Yamamoto, Anthony Venida, Julian Yano, Douglas E Biancur, Miwako Kakiuchi, Suprit Gupta, Albert S W Sohn, Subhadip Mukhopadhyay, Elaine Y Lin, Seth J Parker,[...]. Nature 2020
270
9

Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations.
Annan Yang, N V Rajeshkumar, Xiaoxu Wang, Shinichi Yabuuchi, Brian M Alexander, Gerald C Chu, Daniel D Von Hoff, Anirban Maitra, Alec C Kimmelman. Cancer Discov 2014
301
9

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Kirsten L Bryant, Clint A Stalnecker, Daniel Zeitouni, Jennifer E Klomp, Sen Peng, Andrey P Tikunov, Venugopal Gunda, Mariaelena Pierobon, Andrew M Waters, Samuel D George,[...]. Nat Med 2019
275
9

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.
Jessie Yanxiang Guo, Hsin-Yi Chen, Robin Mathew, Jing Fan, Anne M Strohecker, Gizem Karsli-Uzunbas, Jurre J Kamphorst, Guanghua Chen, Johanna M S Lemons, Vassiliki Karantza,[...]. Genes Dev 2011
878
9

Autophagy pathway: Cellular and molecular mechanisms.
Li Yu, Yang Chen, Sharon A Tooze. Autophagy 2018
565
9

Autophagy in malignant transformation and cancer progression.
Lorenzo Galluzzi, Federico Pietrocola, José Manuel Bravo-San Pedro, Ravi K Amaravadi, Eric H Baehrecke, Francesco Cecconi, Patrice Codogno, Jayanta Debnath, David A Gewirtz, Vassiliki Karantza,[...]. EMBO J 2015
758
8

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis.
Jessie Yanxiang Guo, Gizem Karsli-Uzunbas, Robin Mathew, Seena C Aisner, Jurre J Kamphorst, Anne M Strohecker, Guanghua Chen, Sandy Price, Wenyun Lu, Xin Teng,[...]. Genes Dev 2013
406
8

The role of Atg proteins in autophagosome formation.
Noboru Mizushima, Tamotsu Yoshimori, Yoshinori Ohsumi. Annu Rev Cell Dev Biol 2011
8

Autophagy and multidrug resistance in cancer.
Ying-Jie Li, Yu-He Lei, Nan Yao, Chen-Ran Wang, Nan Hu, Wen-Cai Ye, Dong-Mei Zhang, Zhe-Sheng Chen. Chin J Cancer 2017
287
8

Autophagy is required for glucose homeostasis and lung tumor maintenance.
Gizem Karsli-Uzunbas, Jessie Yanxiang Guo, Sandy Price, Xin Teng, Saurabh V Laddha, Sinan Khor, Nada Y Kalaany, Tyler Jacks, Chang S Chan, Joshua D Rabinowitz,[...]. Cancer Discov 2014
337
8

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor.
Zhenyu Yue, Shengkan Jin, Chingwen Yang, Arnold J Levine, Nathaniel Heintz. Proc Natl Acad Sci U S A 2003
8

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Daniel J Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, Abraham Acevedo Arozena, Hiroaki Adachi, Christopher M Adams, Peter D Adams, Khosrow Adeli,[...]. Autophagy 2016
8

Autophagy and metabolism.
Joshua D Rabinowitz, Eileen White. Science 2010
8

Cancer statistics, 2020.
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2020
8

The double-edged sword of autophagy modulation in cancer.
Eileen White, Robert S DiPaola. Clin Cancer Res 2009
811
8

Autophagy and the integrated stress response.
Guido Kroemer, Guillermo Mariño, Beth Levine. Mol Cell 2010
8

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
8

Pancreatic cancers require autophagy for tumor growth.
Shenghong Yang, Xiaoxu Wang, Gianmarco Contino, Marc Liesa, Ergun Sahin, Haoqiang Ying, Alexandra Bause, Yinghua Li, Jayne M Stommel, Giacomo Dell'antonio,[...]. Genes Dev 2011
948
7

Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells.
Jessie Yanxiang Guo, Xin Teng, Saurabh V Laddha, Sirui Ma, Stephen C Van Nostrand, Yang Yang, Sinan Khor, Chang S Chan, Joshua D Rabinowitz, Eileen White. Genes Dev 2016
213
7

p53 status determines the role of autophagy in pancreatic tumour development.
Mathias T Rosenfeldt, Jim O'Prey, Jennifer P Morton, Colin Nixon, Gillian MacKay, Agata Mrowinska, Amy Au, Taranjit Singh Rai, Liang Zheng, Rachel Ridgway,[...]. Nature 2013
475
7

Autophagy suppresses tumorigenesis through elimination of p62.
Robin Mathew, Cristina M Karp, Brian Beaudoin, Nhan Vuong, Guanghua Chen, Hsin-Yi Chen, Kevin Bray, Anupama Reddy, Gyan Bhanot, Celine Gelinas,[...]. Cell 2009
7

p62 in Cancer: Signaling Adaptor Beyond Autophagy.
Jorge Moscat, Michael Karin, Maria T Diaz-Meco. Cell 2016
233
7

The machinery of macroautophagy.
Yuchen Feng, Ding He, Zhiyuan Yao, Daniel J Klionsky. Cell Res 2014
7

The Roles of Autophagy in Cancer.
Chul Won Yun, Sang Hun Lee. Int J Mol Sci 2018
306
7

The role of autophagy in cancer development and response to therapy.
Yasuko Kondo, Takao Kanzawa, Raymond Sawaya, Seiji Kondo. Nat Rev Cancer 2005
6

Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion.
Rebecca Lock, Candia M Kenific, Andrew M Leidal, Eduardo Salas, Jayanta Debnath. Cancer Discov 2014
176
6

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates.
Daniel F Egan, Matthew G H Chun, Mitchell Vamos, Haixia Zou, Juan Rong, Chad J Miller, Hua Jane Lou, Dhanya Raveendra-Panickar, Chih-Cheng Yang, Douglas J Sheffler,[...]. Mol Cell 2015
395
6

The role of autophagy during the early neonatal starvation period.
Akiko Kuma, Masahiko Hatano, Makoto Matsui, Akitsugu Yamamoto, Haruaki Nakaya, Tamotsu Yoshimori, Yoshinori Ohsumi, Takeshi Tokuhisa, Noboru Mizushima. Nature 2004
6

Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
Rushika M Perera, Svetlana Stoykova, Brandon N Nicolay, Kenneth N Ross, Julien Fitamant, Myriam Boukhali, Justine Lengrand, Vikram Deshpande, Martin K Selig, Cristina R Ferrone,[...]. Nature 2015
461
6

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy.
Christina H Eng, Zuncai Wang, Diane Tkach, Lourdes Toral-Barza, Savuth Ugwonali, Shanming Liu, Stephanie L Fitzgerald, Elizabeth George, Elizabeth Frias, Nadire Cochran,[...]. Proc Natl Acad Sci U S A 2016
140
6

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers.
Conan G Kinsey, Soledad A Camolotto, Amelie M Boespflug, Katrin P Guillen, Mona Foth, Amanda Truong, Sophia S Schuman, Jill E Shea, Michael T Seipp, Jeffrey T Yap,[...]. Nat Med 2019
278
6

Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency.
Quentin McAfee, Zhihui Zhang, Arabinda Samanta, Samuel M Levi, Xiao-Hong Ma, Shengfu Piao, John P Lynch, Takeshi Uehara, Antonia R Sepulveda, Lisa E Davis,[...]. Proc Natl Acad Sci U S A 2012
260
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.