Hai-Qiang Dai, Bang-An Wang, Lu Yang, Jia-Jia Chen, Guo-Chun Zhu, Mei-Ling Sun, Hao Ge, Rui Wang, Deborah L Chapman, Fuchou Tang, Xin Sun, Guo-Liang Xu. Nature 2016
Times Cited: 101
Times Cited: 101
Times Cited
Times Co-cited
Similarity
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
47
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
41
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li,[...]. Science 2011
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li,[...]. Science 2011
36
Loss of Tet enzymes compromises proper differentiation of embryonic stem cells.
Meelad M Dawlaty, Achim Breiling, Thuc Le, M Inmaculada Barrasa, Günter Raddatz, Qing Gao, Benjamin E Powell, Albert W Cheng, Kym F Faull, Frank Lyko,[...]. Dev Cell 2014
Meelad M Dawlaty, Achim Breiling, Thuc Le, M Inmaculada Barrasa, Günter Raddatz, Qing Gao, Benjamin E Powell, Albert W Cheng, Kym F Faull, Frank Lyko,[...]. Dev Cell 2014
33
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes.
Tian-Peng Gu, Fan Guo, Hui Yang, Hai-Ping Wu, Gui-Fang Xu, Wei Liu, Zhi-Guo Xie, Linyu Shi, Xinyi He, Seung-gi Jin,[...]. Nature 2011
Tian-Peng Gu, Fan Guo, Hui Yang, Hai-Ping Wu, Gui-Fang Xu, Wei Liu, Zhi-Guo Xie, Linyu Shi, Xinyi He, Seung-gi Jin,[...]. Nature 2011
32
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
Shinsuke Ito, Ana C D'Alessio, Olena V Taranova, Kwonho Hong, Lawrence C Sowers, Yi Zhang. Nature 2010
Shinsuke Ito, Ana C D'Alessio, Olena V Taranova, Kwonho Hong, Lawrence C Sowers, Yi Zhang. Nature 2010
30
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.
M Okano, D W Bell, D A Haber, E Li. Cell 1999
M Okano, D W Bell, D A Haber, E Li. Cell 1999
27
Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.
Meelad M Dawlaty, Achim Breiling, Thuc Le, Günter Raddatz, M Inmaculada Barrasa, Albert W Cheng, Qing Gao, Benjamin E Powell, Zhe Li, Mingjiang Xu,[...]. Dev Cell 2013
Meelad M Dawlaty, Achim Breiling, Thuc Le, Günter Raddatz, M Inmaculada Barrasa, Albert W Cheng, Qing Gao, Benjamin E Powell, Zhe Li, Mingjiang Xu,[...]. Dev Cell 2013
26
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.
Meelad M Dawlaty, Kibibi Ganz, Benjamin E Powell, Yueh-Chiang Hu, Styliani Markoulaki, Albert W Cheng, Qing Gao, Jongpil Kim, Sang-Woon Choi, David C Page,[...]. Cell Stem Cell 2011
Meelad M Dawlaty, Kibibi Ganz, Benjamin E Powell, Yueh-Chiang Hu, Styliani Markoulaki, Albert W Cheng, Qing Gao, Jongpil Kim, Sang-Woon Choi, David C Page,[...]. Cell Stem Cell 2011
25
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.
Kristine Williams, Jesper Christensen, Marianne Terndrup Pedersen, Jens V Johansen, Paul A C Cloos, Juri Rappsilber, Kristian Helin. Nature 2011
Kristine Williams, Jesper Christensen, Marianne Terndrup Pedersen, Jens V Johansen, Paul A C Cloos, Juri Rappsilber, Kristian Helin. Nature 2011
25
TET-mediated active DNA demethylation: mechanism, function and beyond.
Xiaoji Wu, Yi Zhang. Nat Rev Genet 2017
Xiaoji Wu, Yi Zhang. Nat Rev Genet 2017
25
DNA methylation: roles in mammalian development.
Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
24
Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling.
Xiang Li, Xiaojing Yue, William A Pastor, Lizhu Lin, Romain Georges, Lukas Chavez, Sylvia M Evans, Anjana Rao. Proc Natl Acad Sci U S A 2016
Xiang Li, Xiaojing Yue, William A Pastor, Lizhu Lin, Romain Georges, Lukas Chavez, Sylvia M Evans, Anjana Rao. Proc Natl Acad Sci U S A 2016
41
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.
Cornelia G Spruijt, Felix Gnerlich, Arne H Smits, Toni Pfaffeneder, Pascal W T C Jansen, Christina Bauer, Martin Münzel, Mirko Wagner, Markus Müller, Fariha Khan,[...]. Cell 2013
Cornelia G Spruijt, Felix Gnerlich, Arne H Smits, Toni Pfaffeneder, Pascal W T C Jansen, Christina Bauer, Martin Münzel, Mirko Wagner, Markus Müller, Fariha Khan,[...]. Cell 2013
22
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Kelly Moran-Crusio, Linsey Reavie, Alan Shih, Omar Abdel-Wahab, Delphine Ndiaye-Lobry, Camille Lobry, Maria E Figueroa, Aparna Vasanthakumar, Jay Patel, Xinyang Zhao,[...]. Cancer Cell 2011
Kelly Moran-Crusio, Linsey Reavie, Alan Shih, Omar Abdel-Wahab, Delphine Ndiaye-Lobry, Camille Lobry, Maria E Figueroa, Aparna Vasanthakumar, Jay Patel, Xinyang Zhao,[...]. Cancer Cell 2011
22
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.
Kian Peng Koh, Akiko Yabuuchi, Sridhar Rao, Yun Huang, Kerrianne Cunniff, Julie Nardone, Asta Laiho, Mamta Tahiliani, Cesar A Sommer, Gustavo Mostoslavsky,[...]. Cell Stem Cell 2011
Kian Peng Koh, Akiko Yabuuchi, Sridhar Rao, Yun Huang, Kerrianne Cunniff, Julie Nardone, Asta Laiho, Mamta Tahiliani, Cesar A Sommer, Gustavo Mostoslavsky,[...]. Cell Stem Cell 2011
22
5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation.
Gary C Hon, Chun-Xiao Song, Tingting Du, Fulai Jin, Siddarth Selvaraj, Ah Young Lee, Chia-An Yen, Zhen Ye, Shi-Qing Mao, Bang-An Wang,[...]. Mol Cell 2014
Gary C Hon, Chun-Xiao Song, Tingting Du, Fulai Jin, Siddarth Selvaraj, Ah Young Lee, Chia-An Yen, Zhen Ye, Shi-Qing Mao, Bang-An Wang,[...]. Mol Cell 2014
21
5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming.
Mark Wossidlo, Toshinobu Nakamura, Konstantin Lepikhov, C Joana Marques, Valeri Zakhartchenko, Michele Boiani, Julia Arand, Toru Nakano, Wolf Reik, Jörn Walter. Nat Commun 2011
Mark Wossidlo, Toshinobu Nakamura, Konstantin Lepikhov, C Joana Marques, Valeri Zakhartchenko, Michele Boiani, Julia Arand, Toru Nakano, Wolf Reik, Jörn Walter. Nat Commun 2011
21
TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells.
Nipun Verma, Heng Pan, Louis C Doré, Abhijit Shukla, Qing V Li, Bobbie Pelham-Webb, Virginia Teijeiro, Federico González, Andrei Krivtsov, Chan-Jung Chang,[...]. Nat Genet 2018
Nipun Verma, Heng Pan, Louis C Doré, Abhijit Shukla, Qing V Li, Bobbie Pelham-Webb, Virginia Teijeiro, Federico González, Andrei Krivtsov, Chan-Jung Chang,[...]. Nat Genet 2018
21
Role of Tet proteins in enhancer activity and telomere elongation.
Falong Lu, Yuting Liu, Lan Jiang, Shinpei Yamaguchi, Yi Zhang. Genes Dev 2014
Falong Lu, Yuting Liu, Lan Jiang, Shinpei Yamaguchi, Yi Zhang. Genes Dev 2014
20
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain.
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
20
Active DNA demethylation at enhancers during the vertebrate phylotypic period.
Ozren Bogdanović, Arne H Smits, Elisa de la Calle Mustienes, Juan J Tena, Ethan Ford, Ruth Williams, Upeka Senanayake, Matthew D Schultz, Saartje Hontelez, Ila van Kruijsbergen,[...]. Nat Genet 2016
Ozren Bogdanović, Arne H Smits, Elisa de la Calle Mustienes, Juan J Tena, Ethan Ford, Ruth Williams, Upeka Senanayake, Matthew D Schultz, Saartje Hontelez, Ila van Kruijsbergen,[...]. Nat Genet 2016
19
Lineage-specific functions of TET1 in the postimplantation mouse embryo.
Rita Khoueiry, Abhishek Sohni, Bernard Thienpont, Xinlong Luo, Joris Vande Velde, Michela Bartoccetti, Bram Boeckx, An Zwijsen, Anjana Rao, Diether Lambrechts,[...]. Nat Genet 2017
Rita Khoueiry, Abhishek Sohni, Bernard Thienpont, Xinlong Luo, Joris Vande Velde, Michela Bartoccetti, Bram Boeckx, An Zwijsen, Anjana Rao, Diether Lambrechts,[...]. Nat Genet 2017
33
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality.
E Li, T H Bestor, R Jaenisch. Cell 1992
E Li, T H Bestor, R Jaenisch. Cell 1992
18
Reversing DNA methylation: mechanisms, genomics, and biological functions.
Hao Wu, Yi Zhang. Cell 2014
Hao Wu, Yi Zhang. Cell 2014
18
Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies.
Zhe Li, Xiaoqiang Cai, Chen-Leng Cai, Jiapeng Wang, Wenyong Zhang, Bruce E Petersen, Feng-Chun Yang, Mingjiang Xu. Blood 2011
Zhe Li, Xiaoqiang Cai, Chen-Leng Cai, Jiapeng Wang, Wenyong Zhang, Bruce E Petersen, Feng-Chun Yang, Mingjiang Xu. Blood 2011
17
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.
Hao Wu, Ana C D'Alessio, Shinsuke Ito, Kai Xia, Zhibin Wang, Kairong Cui, Keji Zhao, Yi Eve Sun, Yi Zhang. Nature 2011
Hao Wu, Ana C D'Alessio, Shinsuke Ito, Kai Xia, Zhibin Wang, Kairong Cui, Keji Zhao, Yi Eve Sun, Yi Zhang. Nature 2011
17
Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence.
Cheng Li, Yahui Lan, Lianna Schwartz-Orbach, Evgenia Korol, Mamta Tahiliani, Todd Evans, Mary G Goll. Cell Rep 2015
Cheng Li, Yahui Lan, Lianna Schwartz-Orbach, Evgenia Korol, Mamta Tahiliani, Todd Evans, Mary G Goll. Cell Rep 2015
28
Active and passive demethylation of male and female pronuclear DNA in the mammalian zygote.
Fan Guo, Xianlong Li, Dan Liang, Tong Li, Ping Zhu, Hongshan Guo, Xinglong Wu, Lu Wen, Tian-Peng Gu, Boqiang Hu,[...]. Cell Stem Cell 2014
Fan Guo, Xianlong Li, Dan Liang, Tong Li, Ping Zhu, Hongshan Guo, Xinglong Wu, Lu Wen, Tian-Peng Gu, Boqiang Hu,[...]. Cell Stem Cell 2014
16
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription.
William A Pastor, L Aravind, Anjana Rao. Nat Rev Mol Cell Biol 2013
William A Pastor, L Aravind, Anjana Rao. Nat Rev Mol Cell Biol 2013
16
Role of TET enzymes in DNA methylation, development, and cancer.
Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
16
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells.
Stefanie Seisenberger, Simon Andrews, Felix Krueger, Julia Arand, Jörn Walter, Fátima Santos, Christian Popp, Bernard Thienpont, Wendy Dean, Wolf Reik. Mol Cell 2012
Stefanie Seisenberger, Simon Andrews, Felix Krueger, Julia Arand, Jörn Walter, Fátima Santos, Christian Popp, Bernard Thienpont, Wendy Dean, Wolf Reik. Mol Cell 2012
16
Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis.
Jinsuk Kang, Matthias Lienhard, William A Pastor, Ashu Chawla, Mark Novotny, Ageliki Tsagaratou, Roger S Lasken, Elizabeth C Thompson, M Azim Surani, Sergei B Koralov,[...]. Proc Natl Acad Sci U S A 2015
Jinsuk Kang, Matthias Lienhard, William A Pastor, Ashu Chawla, Mark Novotny, Ageliki Tsagaratou, Roger S Lasken, Elizabeth C Thompson, M Azim Surani, Sergei B Koralov,[...]. Proc Natl Acad Sci U S A 2015
25
Model-based analysis of ChIP-Seq (MACS).
Yong Zhang, Tao Liu, Clifford A Meyer, Jérôme Eeckhoute, David S Johnson, Bradley E Bernstein, Chad Nusbaum, Richard M Myers, Myles Brown, Wei Li,[...]. Genome Biol 2008
Yong Zhang, Tao Liu, Clifford A Meyer, Jérôme Eeckhoute, David S Johnson, Bradley E Bernstein, Chad Nusbaum, Richard M Myers, Myles Brown, Wei Li,[...]. Genome Biol 2008
16
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine.
Khursheed Iqbal, Seung-Gi Jin, Gerd P Pfeifer, Piroska E Szabó. Proc Natl Acad Sci U S A 2011
Khursheed Iqbal, Seung-Gi Jin, Gerd P Pfeifer, Piroska E Szabó. Proc Natl Acad Sci U S A 2011
15
De novo DNA methylation drives 5hmC accumulation in mouse zygotes.
Rachel Amouroux, Buhe Nashun, Kenjiro Shirane, Shoma Nakagawa, Peter Ws Hill, Zelpha D'Souza, Manabu Nakayama, Masashi Matsuda, Aleksandra Turp, Elodie Ndjetehe,[...]. Nat Cell Biol 2016
Rachel Amouroux, Buhe Nashun, Kenjiro Shirane, Shoma Nakagawa, Peter Ws Hill, Zelpha D'Souza, Manabu Nakayama, Masashi Matsuda, Aleksandra Turp, Elodie Ndjetehe,[...]. Nat Cell Biol 2016
15
Tet3 and DNA replication mediate demethylation of both the maternal and paternal genomes in mouse zygotes.
Li Shen, Azusa Inoue, Jin He, Yuting Liu, Falong Lu, Yi Zhang. Cell Stem Cell 2014
Li Shen, Azusa Inoue, Jin He, Yuting Liu, Falong Lu, Yi Zhang. Cell Stem Cell 2014
14
DNA-binding factors shape the mouse methylome at distal regulatory regions.
Michael B Stadler, Rabih Murr, Lukas Burger, Robert Ivanek, Florian Lienert, Anne Schöler, Erik van Nimwegen, Christiane Wirbelauer, Edward J Oakeley, Dimos Gaidatzis,[...]. Nature 2011
Michael B Stadler, Rabih Murr, Lukas Burger, Robert Ivanek, Florian Lienert, Anne Schöler, Erik van Nimwegen, Christiane Wirbelauer, Edward J Oakeley, Dimos Gaidatzis,[...]. Nature 2011
14
Reprogramming the methylome: erasing memory and creating diversity.
Heather J Lee, Timothy A Hore, Wolf Reik. Cell Stem Cell 2014
Heather J Lee, Timothy A Hore, Wolf Reik. Cell Stem Cell 2014
14
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.
Myunggon Ko, Jungeun An, Hozefa S Bandukwala, Lukas Chavez, Tarmo Aijö, William A Pastor, Matthew F Segal, Huiming Li, Kian Peng Koh, Harri Lähdesmäki,[...]. Nature 2013
Myunggon Ko, Jungeun An, Hozefa S Bandukwala, Lukas Chavez, Tarmo Aijö, William A Pastor, Matthew F Segal, Huiming Li, Kian Peng Koh, Harri Lähdesmäki,[...]. Nature 2013
13
Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development.
Yufei Xu, Chao Xu, Akiko Kato, Wolfram Tempel, Jose Garcia Abreu, Chuanbing Bian, Yeguang Hu, Di Hu, Bin Zhao, Tanja Cerovina,[...]. Cell 2012
Yufei Xu, Chao Xu, Akiko Kato, Wolfram Tempel, Jose Garcia Abreu, Chuanbing Bian, Yeguang Hu, Di Hu, Bin Zhao, Tanja Cerovina,[...]. Cell 2012
13
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites.
Atanu Maiti, Alexander C Drohat. J Biol Chem 2011
Atanu Maiti, Alexander C Drohat. J Biol Chem 2011
13
Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.
Jamie A Hackett, Roopsha Sengupta, Jan J Zylicz, Kazuhiro Murakami, Caroline Lee, Thomas A Down, M Azim Surani. Science 2013
Jamie A Hackett, Roopsha Sengupta, Jan J Zylicz, Kazuhiro Murakami, Caroline Lee, Thomas A Down, M Azim Surani. Science 2013
13
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.
Gabriella Ficz, Miguel R Branco, Stefanie Seisenberger, Fátima Santos, Felix Krueger, Timothy A Hore, C Joana Marques, Simon Andrews, Wolf Reik. Nature 2011
Gabriella Ficz, Miguel R Branco, Stefanie Seisenberger, Fátima Santos, Felix Krueger, Timothy A Hore, C Joana Marques, Simon Andrews, Wolf Reik. Nature 2011
13
A unique regulatory phase of DNA methylation in the early mammalian embryo.
Zachary D Smith, Michelle M Chan, Tarjei S Mikkelsen, Hongcang Gu, Andreas Gnirke, Aviv Regev, Alexander Meissner. Nature 2012
Zachary D Smith, Michelle M Chan, Tarjei S Mikkelsen, Hongcang Gu, Andreas Gnirke, Aviv Regev, Alexander Meissner. Nature 2012
13
Tet1 regulates adult hippocampal neurogenesis and cognition.
Run-Rui Zhang, Qing-Yan Cui, Kiyohito Murai, Yen Ching Lim, Zachary D Smith, Shengnan Jin, Peng Ye, Luis Rosa, Yew Kok Lee, Hai-Ping Wu,[...]. Cell Stem Cell 2013
Run-Rui Zhang, Qing-Yan Cui, Kiyohito Murai, Yen Ching Lim, Zachary D Smith, Shengnan Jin, Peng Ye, Luis Rosa, Yew Kok Lee, Hai-Ping Wu,[...]. Cell Stem Cell 2013
13
Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation.
Hideharu Hashimoto, Yiwei Liu, Anup K Upadhyay, Yanqi Chang, Shelley B Howerton, Paula M Vertino, Xing Zhang, Xiaodong Cheng. Nucleic Acids Res 2012
Hideharu Hashimoto, Yiwei Liu, Anup K Upadhyay, Yanqi Chang, Shelley B Howerton, Paula M Vertino, Xing Zhang, Xiaodong Cheng. Nucleic Acids Res 2012
12
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair.
Salvatore Cortellino, Jinfei Xu, Mara Sannai, Robert Moore, Elena Caretti, Antonio Cigliano, Madeleine Le Coz, Karthik Devarajan, Andy Wessels, Dianne Soprano,[...]. Cell 2011
Salvatore Cortellino, Jinfei Xu, Mara Sannai, Robert Moore, Elena Caretti, Antonio Cigliano, Madeleine Le Coz, Karthik Devarajan, Andy Wessels, Dianne Soprano,[...]. Cell 2011
12
NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.
Yael Costa, Junjun Ding, Thorold W Theunissen, Francesco Faiola, Timothy A Hore, Pavel V Shliaha, Miguel Fidalgo, Arven Saunders, Moyra Lawrence, Sabine Dietmann,[...]. Nature 2013
Yael Costa, Junjun Ding, Thorold W Theunissen, Francesco Faiola, Timothy A Hore, Pavel V Shliaha, Miguel Fidalgo, Arven Saunders, Moyra Lawrence, Sabine Dietmann,[...]. Nature 2013
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.