A citation-based method for searching scientific literature


List of co-cited articles
499 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Inhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of Huntington's disease.
Carmela Giampà, Daunia Laurenti, Serenella Anzilotti, Giorgio Bernardi, Frank S Menniti, Francesca Romana Fusco. PLoS One 2010
139
60

Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington's Disease Models.
Vahri Beaumont, Sheng Zhong, Hai Lin, WenJin Xu, Amyaouch Bradaia, Esther Steidl, Melanie Gleyzes, Kristian Wadel, Bruno Buisson, Fernando E Padovan-Neto,[...]. Neuron 2016
68
47

PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a Huntington's disease mouse model.
Albert Giralt, Ana Saavedra, Olga Carretón, Helena Arumí, Shiraz Tyebji, Jordi Alberch, Esther Pérez-Navarro. Hippocampus 2013
60
43

Immunohistochemical localization of PDE10A in the rat brain.
Thomas F Seeger, Brenda Bartlett, Timothy M Coskran, Jeffrey S Culp, Larry C James, David L Krull, Jerry Lanfear, Anne M Ryan, Christopher J Schmidt, Christine A Strick,[...]. Brain Res 2003
277
39

Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinson's disease.
Flavia Niccolini, Thomas Foltynie, Tiago Reis Marques, Nils Muhlert, Andri C Tziortzi, Graham E Searle, Sridhar Natesan, Shitij Kapur, Eugenii A Rabiner, Roger N Gunn,[...]. Brain 2015
78
39

Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase.
Z Xie, W O Adamowicz, W D Eldred, A B Jakowski, R J Kleiman, D G Morton, D T Stephenson, C A Strick, R D Williams, F S Menniti. Neuroscience 2006
159
39

Mammalian cyclic nucleotide phosphodiesterases: molecular mechanisms and physiological functions.
Sharron H Francis, Mitsi A Blount, Jackie D Corbin. Physiol Rev 2011
427
34

TAK-063, a PDE10A Inhibitor with Balanced Activation of Direct and Indirect Pathways, Provides Potent Antipsychotic-Like Effects in Multiple Paradigms.
Kazunori Suzuki, Akina Harada, Hirobumi Suzuki, Maki Miyamoto, Haruhide Kimura. Neuropsychopharmacology 2016
38
30

Phosphodiesterase 10A inhibitor activity in preclinical models of the positive, cognitive, and negative symptoms of schizophrenia.
Steven M Grauer, Virginia L Pulito, Rachel L Navarra, Michele P Kelly, Cody Kelley, Radka Graf, Barbara Langen, Sheree Logue, Julie Brennan, Lixin Jiang,[...]. J Pharmacol Exp Ther 2009
217
30

Phosphodiesterase 10 inhibition reduces striatal excitotoxicity in the quinolinic acid model of Huntington's disease.
Carmela Giampà, Stefano Patassini, Antonella Borreca, Daunia Laurenti, Fabrizia Marullo, Giorgio Bernardi, Frank S Menniti, Francesca R Fusco. Neurobiol Dis 2009
57
30


Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia.
C J Schmidt, D S Chapin, J Cianfrogna, M L Corman, M Hajos, J F Harms, W E Hoffman, L A Lebel, S A McCarthy, F R Nelson,[...]. J Pharmacol Exp Ther 2008
235
30

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use.
Andrew T Bender, Joseph A Beavo. Pharmacol Rev 2006
26

PET imaging shows loss of striatal PDE10A in patients with Huntington disease.
Rawaha Ahmad, Sophie Bourgeois, Andrey Postnov, Mark E Schmidt, Guy Bormans, Koen Van Laere, Wim Vandenberghe. Neurology 2014
56
26

Phosphodiesterase 10A (PDE10A) localization in the R6/2 mouse model of Huntington's disease.
Alessandro Leuti, Daunia Laurenti, Carmela Giampà, Elena Montagna, Clemente Dato, Serenella Anzilotti, Mariarosa A B Melone, Giorgio Bernardi, Francesca R Fusco. Neurobiol Dis 2013
38
26

PDE10A inhibitors: novel therapeutic drugs for schizophrenia.
Jan Kehler, Jacob Nielsen. Curr Pharm Des 2011
93
26


Altered PDE10A expression detectable early before symptomatic onset in Huntington's disease.
Flavia Niccolini, Salman Haider, Tiago Reis Marques, Nils Muhlert, Andri C Tziortzi, Graham E Searle, Sridhar Natesan, Paola Piccini, Shitij Kapur, Eugenii A Rabiner,[...]. Brain 2015
68
26

Phosphodiesterase 10 inhibitors: new disease modifying drugs for Parkinson's disease?
A M García, M Redondo, A Martinez, C Gil. Curr Med Chem 2014
16
31

Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum.
Akinori Nishi, Mahomi Kuroiwa, Diane B Miller, James P O'Callaghan, Helen S Bateup, Takahide Shuto, Naoki Sotogaku, Takaichi Fukuda, Nathaniel Heintz, Paul Greengard,[...]. J Neurosci 2008
204
21

Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice.
Silvia Gines, Ihn Sik Seong, Elisa Fossale, Elena Ivanova, Flavia Trettel, James F Gusella, Vanessa C Wheeler, Francesca Persichetti, Marcy E MacDonald. Hum Mol Genet 2003
211
21

Mutant huntingtin affects the rate of transcription of striatum-specific isoforms of phosphodiesterase 10A.
Haibei Hu, Elizabeth A McCaw, Andrea L O Hebb, Geraldine T Gomez, Eileen M Denovan-Wright. Eur J Neurosci 2004
61
21

Loss of extra-striatal phosphodiesterase 10A expression in early premanifest Huntington's disease gene carriers.
Heather Wilson, Flavia Niccolini, Salman Haider, Tiago Reis Marques, Gennaro Pagano, Christopher Coello, Sridhar Natesan, Shitij Kapur, Eugenii A Rabiner, Roger N Gunn,[...]. J Neurol Sci 2016
26
21

Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A).
K Fujishige, J Kotera, H Michibata, K Yuasa, S Takebayashi, K Okumura, K Omori. J Biol Chem 1999
328
21

The Phosphodiesterase 10A Selective Inhibitor TAK-063 Improves Cognitive Functions Associated with Schizophrenia in Rodent Models.
Eri Shiraishi, Kazunori Suzuki, Akina Harada, Noriko Suzuki, Haruhide Kimura. J Pharmacol Exp Ther 2016
35
21

Immunohistochemical localization of phosphodiesterase 10A in multiple mammalian species.
Timothy M Coskran, Daniel Morton, Frank S Menniti, Wendy O Adamowicz, Robin J Kleiman, Anne M Ryan, Christine A Strick, Christopher J Schmidt, Diane T Stephenson. J Histochem Cytochem 2006
206
21


Role of brain-derived neurotrophic factor in Huntington's disease.
Chiara Zuccato, Elena Cattaneo. Prog Neurobiol 2007
393
21


Phosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in Striatum.
Corina Russwurm, Doris Koesling, Michael Russwurm. J Biol Chem 2015
30
17

Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A.
S H Soderling, S J Bayuga, J A Beavo. Proc Natl Acad Sci U S A 1999
321
17

Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease.
Albert Giralt, Ana Saavedra, Olga Carretón, Xavier Xifró, Jordi Alberch, Esther Pérez-Navarro. Hum Mol Genet 2011
86
17

A novel mutation of PDE8B Gene in a Japanese family with autosomal-dominant striatal degeneration.
Reo Azuma, Kinya Ishikawa, Kosei Hirata, Yuji Hashimoto, Makoto Takahashi, Kenji Ishii, Akira Inaba, Takanori Yokota, Satoshi Orimo. Mov Disord 2015
10
40

The phosphodiesterase 10 positron emission tomography tracer, [18F]MNI-659, as a novel biomarker for early Huntington disease.
David S Russell, Olivier Barret, Danna L Jennings, Joseph H Friedman, Gilles D Tamagnan, David Thomae, David Alagille, Thomas J Morley, Caroline Papin, Spyridon Papapetropoulos,[...]. JAMA Neurol 2014
59
17


Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling.
Ottavio V Vitolo, Antonino Sant'Angelo, Vincenzo Costanzo, Fortunato Battaglia, Ottavio Arancio, Michael Shelanski. Proc Natl Acad Sci U S A 2002
422
17

Cognitive Dysfunction in Huntington's Disease: Humans, Mouse Models and Molecular Mechanisms.
Albert Giralt, Ana Saavedra, Jordi Alberch, Esther Pérez-Navarro. J Huntingtons Dis 2012
45
17

Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's disease.
Motomasa Tanaka, Koko Ishizuka, Yoko Nekooki-Machida, Ryo Endo, Noriko Takashima, Hideyuki Sasaki, Yusuke Komi, Amy Gathercole, Elaine Huston, Kazuhiro Ishii,[...]. J Clin Invest 2017
23
17

Regulation of feedback between protein kinase A and the proteasome system worsens Huntington's disease.
Jiun-Tsai Lin, Wei-Cheng Chang, Hui-Mei Chen, Hsing-Lin Lai, Chih-Yeh Chen, Mi-Hua Tao, Yijuang Chern. Mol Cell Biol 2013
50
17

Reversal of long-term dendritic spine alterations in Alzheimer disease models.
Donna L Smith, Julio Pozueta, Bing Gong, Ottavio Arancio, Michael Shelanski. Proc Natl Acad Sci U S A 2009
179
17

Radiosynthesis and in vivo evaluation of [11C]MP-10 as a PET probe for imaging PDE10A in rodent and non-human primate brain.
Zhude Tu, Jinda Fan, Shihong Li, Lynne A Jones, Jinquan Cui, Prashanth K Padakanti, Jinbin Xu, Dexing Zeng, Kooresh I Shoghi, Joel S Perlmutter,[...]. Bioorg Med Chem 2011
49
17

A human [(11)C]T-773 PET study of PDE10A binding after oral administration of TAK-063, a PDE10A inhibitor.
Akihiro Takano, Per Stenkrona, Vladimir Stepanov, Nahid Amini, Stefan Martinsson, Max Tsai, Paul Goldsmith, Jinhui Xie, Jingtao Wu, Tolga Uz,[...]. Neuroimage 2016
21
19

Discovery and development of 11C-Lu AE92686 as a radioligand for PET imaging of phosphodiesterase10A in the brain.
Jan Kehler, John Paul Kilburn, Sergio Estrada, Søren Rahn Christensen, Anders Wall, Alf Thibblin, Mark Lubberink, Christoffer Bundgaard, Lise Tøttrup Brennum, Björn Steiniger-Brach,[...]. J Nucl Med 2014
32
17

Discovery of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the treatment of schizophrenia.
Patrick R Verhoest, Douglas S Chapin, Michael Corman, Kari Fonseca, John F Harms, Xinjun Hou, Eric S Marr, Frank S Menniti, Frederick Nelson, Rebecca O'Connor,[...]. J Med Chem 2009
178
17

Characterization of the binding properties of T-773 as a PET radioligand for phosphodiesterase 10A.
Akina Harada, Kazunori Suzuki, Shotaro Miura, Tomoaki Hasui, Naomi Kamiguchi, Tsuyoshi Ishii, Takahiko Taniguchi, Takanobu Kuroita, Akihiro Takano, Vladimir Stepanov,[...]. Nucl Med Biol 2015
26
17

Phosphodiesterases in the CNS: targets for drug development.
Frank S Menniti, W Stephen Faraci, Christopher J Schmidt. Nat Rev Drug Discov 2006
304
17

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
17


Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy.
Christine P Diggle, Stacey J Sukoff Rizzo, Michael Popiolek, Reetta Hinttala, Jan-Philip Schülke, Manju A Kurian, Ian M Carr, Alexander F Markham, David T Bonthron, Christopher Watson,[...]. Am J Hum Genet 2016
49
17

Discovery of 1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one (TAK-063), a highly potent, selective, and orally active phosphodiesterase 10A (PDE10A) inhibitor.
Jun Kunitomo, Masato Yoshikawa, Makoto Fushimi, Akira Kawada, John F Quinn, Hideyuki Oki, Hironori Kokubo, Mitsuyo Kondo, Kosuke Nakashima, Naomi Kamiguchi,[...]. J Med Chem 2014
46
17


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.