Angelika Doetzlhofer, Karen B Avraham. Semin Cell Dev Biol 2017
Times Cited: 22
Times Cited: 22
Times Cited
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Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea.
Juan C Maass, Rende Gu, Martin L Basch, Joerg Waldhaus, Eduardo Martin Lopez, Anping Xia, John S Oghalai, Stefan Heller, Andrew K Groves. Front Cell Neurosci 2015
Juan C Maass, Rende Gu, Martin L Basch, Joerg Waldhaus, Eduardo Martin Lopez, Anping Xia, John S Oghalai, Stefan Heller, Andrew K Groves. Front Cell Neurosci 2015
36
Epigenetic regulation in the inner ear and its potential roles in development, protection, and regeneration.
Wanda S Layman, Jian Zuo. Front Cell Neurosci 2015
Wanda S Layman, Jian Zuo. Front Cell Neurosci 2015
36
Math1: an essential gene for the generation of inner ear hair cells.
N A Bermingham, B A Hassan, S D Price, M A Vollrath, N Ben-Arie, R A Eatock, H J Bellen, A Lysakowski, H Y Zoghbi. Science 1999
N A Bermingham, B A Hassan, S D Price, M A Vollrath, N Ben-Arie, R A Eatock, H J Bellen, A Lysakowski, H Y Zoghbi. Science 1999
36
Epigenetic regulation of Atoh1 guides hair cell development in the mammalian cochlea.
Zlatka P Stojanova, Tao Kwan, Neil Segil. Development 2015
Zlatka P Stojanova, Tao Kwan, Neil Segil. Development 2015
36
Math1 regulates development of the sensory epithelium in the mammalian cochlea.
Chad Woods, Mireille Montcouquiol, Matthew W Kelley. Nat Neurosci 2004
Chad Woods, Mireille Montcouquiol, Matthew W Kelley. Nat Neurosci 2004
31
Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma.
Kunio Mizutari, Masato Fujioka, Makoto Hosoya, Naomi Bramhall, Hirotaka James Okano, Hideyuki Okano, Albert S B Edge. Neuron 2013
Kunio Mizutari, Masato Fujioka, Makoto Hosoya, Naomi Bramhall, Hirotaka James Okano, Hideyuki Okano, Albert S B Edge. Neuron 2013
31
Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo.
Brandon C Cox, Renjie Chai, Anne Lenoir, Zhiyong Liu, LingLi Zhang, Duc-Huy Nguyen, Kavita Chalasani, Katherine A Steigelman, Jie Fang, Edwin W Rubel,[...]. Development 2014
Brandon C Cox, Renjie Chai, Anne Lenoir, Zhiyong Liu, LingLi Zhang, Duc-Huy Nguyen, Kavita Chalasani, Katherine A Steigelman, Jie Fang, Edwin W Rubel,[...]. Development 2014
27
Lgr5-positive supporting cells generate new hair cells in the postnatal cochlea.
Naomi F Bramhall, Fuxin Shi, Katrin Arnold, Konrad Hochedlinger, Albert S B Edge. Stem Cell Reports 2014
Naomi F Bramhall, Fuxin Shi, Katrin Arnold, Konrad Hochedlinger, Albert S B Edge. Stem Cell Reports 2014
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The epigenetic modifier DNMT3A is necessary for proper otic placode formation.
Daniela Roellig, Marianne E Bronner. Dev Biol 2016
Daniela Roellig, Marianne E Bronner. Dev Biol 2016
35
Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway.
Wenyan Li, Jingfang Wu, Jianming Yang, Shan Sun, Renjie Chai, Zheng-Yi Chen, Huawei Li. Proc Natl Acad Sci U S A 2015
Wenyan Li, Jingfang Wu, Jianming Yang, Shan Sun, Renjie Chai, Zheng-Yi Chen, Huawei Li. Proc Natl Acad Sci U S A 2015
22
Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory Hair Cells.
Will J McLean, Xiaolei Yin, Lin Lu, Danielle R Lenz, Dalton McLean, Robert Langer, Jeffrey M Karp, Albert S B Edge. Cell Rep 2017
Will J McLean, Xiaolei Yin, Lin Lu, Danielle R Lenz, Dalton McLean, Robert Langer, Jeffrey M Karp, Albert S B Edge. Cell Rep 2017
22
The ATP-dependent chromatin remodeling enzyme CHD7 regulates pro-neural gene expression and neurogenesis in the inner ear.
Elizabeth A Hurd, Heather K Poucher, Katherine Cheng, Yehoash Raphael, Donna M Martin. Development 2010
Elizabeth A Hurd, Heather K Poucher, Katherine Cheng, Yehoash Raphael, Donna M Martin. Development 2010
22
Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears.
J L Zheng, W Q Gao. Nat Neurosci 2000
J L Zheng, W Q Gao. Nat Neurosci 2000
22
Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors.
Fuxin Shi, Lingxiang Hu, Albert S B Edge. Proc Natl Acad Sci U S A 2013
Fuxin Shi, Lingxiang Hu, Albert S B Edge. Proc Natl Acad Sci U S A 2013
18
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti.
Angelika Doetzlhofer, Martin L Basch, Takahiro Ohyama, Manfred Gessler, Andrew K Groves, Neil Segil. Dev Cell 2009
Angelika Doetzlhofer, Martin L Basch, Takahiro Ohyama, Manfred Gessler, Andrew K Groves, Neil Segil. Dev Cell 2009
18
Selection of cell fate in the organ of Corti involves the integration of Hes/Hey signaling at the Atoh1 promoter.
Yassan Abdolazimi, Zlatka Stojanova, Neil Segil. Development 2016
Yassan Abdolazimi, Zlatka Stojanova, Neil Segil. Development 2016
18
Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing.
Juan C Maass, Rende Gu, Tiantian Cai, Ying-Wooi Wan, Silvia C Cantellano, Joanna S T Asprer, Hongyuan Zhang, Hsin-I Jen, Renée K Edlund, Zhandong Liu,[...]. PLoS One 2016
Juan C Maass, Rende Gu, Tiantian Cai, Ying-Wooi Wan, Silvia C Cantellano, Joanna S T Asprer, Hongyuan Zhang, Hsin-I Jen, Renée K Edlund, Zhandong Liu,[...]. PLoS One 2016
18
Sox2 in the differentiation of cochlear progenitor cells.
Judith S Kempfle, Jack L Turban, Albert S B Edge. Sci Rep 2016
Judith S Kempfle, Jack L Turban, Albert S B Edge. Sci Rep 2016
18
Extensive Supporting Cell Proliferation and Mitotic Hair Cell Generation by In Vivo Genetic Reprogramming in the Neonatal Mouse Cochlea.
Wenli Ni, Chen Lin, Luo Guo, Jingfang Wu, Yan Chen, Renjie Chai, Wenyan Li, Huawei Li. J Neurosci 2016
Wenli Ni, Chen Lin, Luo Guo, Jingfang Wu, Yan Chen, Renjie Chai, Wenyan Li, Huawei Li. J Neurosci 2016
18
Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea.
Renjie Chai, Bryan Kuo, Tian Wang, Eric J Liaw, Anping Xia, Taha A Jan, Zhiyong Liu, Makoto M Taketo, John S Oghalai, Roeland Nusse,[...]. Proc Natl Acad Sci U S A 2012
Renjie Chai, Bryan Kuo, Tian Wang, Eric J Liaw, Anping Xia, Taha A Jan, Zhiyong Liu, Makoto M Taketo, John S Oghalai, Roeland Nusse,[...]. Proc Natl Acad Sci U S A 2012
18
Inhibitors of Histone Deacetylases Attenuate Noise-Induced Hearing Loss.
Jun Chen, Kayla Hill, Su-Hua Sha. J Assoc Res Otolaryngol 2016
Jun Chen, Kayla Hill, Su-Hua Sha. J Assoc Res Otolaryngol 2016
19
Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer.
Samuel P Gubbels, David W Woessner, John C Mitchell, Anthony J Ricci, John V Brigande. Nature 2008
Samuel P Gubbels, David W Woessner, John C Mitchell, Anthony J Ricci, John V Brigande. Nature 2008
18
Molecular mechanisms of inner ear development.
Doris K Wu, Matthew W Kelley. Cold Spring Harb Perspect Biol 2012
Doris K Wu, Matthew W Kelley. Cold Spring Harb Perspect Biol 2012
18
Histone deacetylase inhibition protects hearing against acute ototoxicity by activating the Nf-κB pathway.
W S Layman, D M Williams, J A Dearman, M A Sauceda, J Zuo. Cell Death Discov 2015
W S Layman, D M Williams, J A Dearman, M A Sauceda, J Zuo. Cell Death Discov 2015
18
The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea.
Elizabeth Carroll Driver, Laura Sillers, Thomas M Coate, Matthew F Rose, Matthew W Kelley. Dev Biol 2013
Elizabeth Carroll Driver, Laura Sillers, Thomas M Coate, Matthew F Rose, Matthew W Kelley. Dev Biol 2013
18
Regulation of cell fate in the sensory epithelia of the inner ear.
Matthew W Kelley. Nat Rev Neurosci 2006
Matthew W Kelley. Nat Rev Neurosci 2006
18
Epigenetic DNA Demethylation Causes Inner Ear Stem Cell Differentiation into Hair Cell-Like Cells.
Yang Zhou, Zhengqing Hu. Front Cell Neurosci 2016
Yang Zhou, Zhengqing Hu. Front Cell Neurosci 2016
28
Epigenetic regulation of Atoh1 guides hair cell development in the mammalian cochlea.
Zlatka P Stojanova, Tao Kwan, Neil Segil. Development 2016
Zlatka P Stojanova, Tao Kwan, Neil Segil. Development 2016
25
DNA methylation dynamics during embryonic development and postnatal maturation of the mouse auditory sensory epithelium.
Ofer Yizhar-Barnea, Cristina Valensisi, Naresh Doni Jayavelu, Kamal Kishore, Colin Andrus, Tal Koffler-Brill, Kathy Ushakov, Kobi Perl, Yael Noy, Yoni Bhonker,[...]. Sci Rep 2018
Ofer Yizhar-Barnea, Cristina Valensisi, Naresh Doni Jayavelu, Kamal Kishore, Colin Andrus, Tal Koffler-Brill, Kathy Ushakov, Kobi Perl, Yael Noy, Yoni Bhonker,[...]. Sci Rep 2018
22
Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression.
Zhiyong Liu, Jennifer A Dearman, Brandon C Cox, Brandon J Walters, Lingli Zhang, Olivier Ayrault, Frederique Zindy, Lin Gan, Martine F Roussel, Jian Zuo. J Neurosci 2012
Zhiyong Liu, Jennifer A Dearman, Brandon C Cox, Brandon J Walters, Lingli Zhang, Olivier Ayrault, Frederique Zindy, Lin Gan, Martine F Roussel, Jian Zuo. J Neurosci 2012
18
Regeneration of Cochlear Hair Cells and Hearing Recovery through Hes1 Modulation with siRNA Nanoparticles in Adult Guinea Pigs.
Xiaoping Du, Qunfeng Cai, Matthew B West, Ibrahima Youm, Xiangping Huang, Wei Li, Weihua Cheng, Don Nakmali, Donald L Ewert, Richard D Kopke. Mol Ther 2018
Xiaoping Du, Qunfeng Cai, Matthew B West, Ibrahima Youm, Xiangping Huang, Wei Li, Weihua Cheng, Don Nakmali, Donald L Ewert, Richard D Kopke. Mol Ther 2018
18
Wnt-responsive Lgr5-expressing stem cells are hair cell progenitors in the cochlea.
Fuxin Shi, Judith S Kempfle, Albert S B Edge. J Neurosci 2012
Fuxin Shi, Judith S Kempfle, Albert S B Edge. J Neurosci 2012
18
Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice.
Stephanie A Bucks, Brandon C Cox, Brittany A Vlosich, James P Manning, Tot B Nguyen, Jennifer S Stone. Elife 2017
Stephanie A Bucks, Brandon C Cox, Brittany A Vlosich, James P Manning, Tot B Nguyen, Jennifer S Stone. Elife 2017
18
Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells.
Patricia M White, Angelika Doetzlhofer, Yun Shain Lee, Andrew K Groves, Neil Segil. Nature 2006
Patricia M White, Angelika Doetzlhofer, Yun Shain Lee, Andrew K Groves, Neil Segil. Nature 2006
18
Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1.
Hsin-I Jen, Matthew C Hill, Litao Tao, Kuanwei Sheng, Wenjian Cao, Hongyuan Zhang, Haoze V Yu, Juan Llamas, Chenghang Zong, James F Martin,[...]. Elife 2019
Hsin-I Jen, Matthew C Hill, Litao Tao, Kuanwei Sheng, Wenjian Cao, Hongyuan Zhang, Haoze V Yu, Juan Llamas, Chenghang Zong, James F Martin,[...]. Elife 2019
18
Ectopic expression of activated notch or SOX2 reveals similar and unique roles in the development of the sensory cell progenitors in the mammalian inner ear.
Wei Pan, Ying Jin, Jing Chen, Robbert J Rottier, Karen P Steel, Amy E Kiernan. J Neurosci 2013
Wei Pan, Ying Jin, Jing Chen, Robbert J Rottier, Karen P Steel, Amy E Kiernan. J Neurosci 2013
13
Dual role for Sox2 in specification of sensory competence and regulation of Atoh1 function.
Chandrakala Puligilla, Matthew W Kelley. Dev Neurobiol 2017
Chandrakala Puligilla, Matthew W Kelley. Dev Neurobiol 2017
14
Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas.
Norio Yamamoto, Kenji Tanigaki, Masayuki Tsuji, Daisuke Yabe, Juichi Ito, Tasuku Honjo. J Mol Med (Berl) 2006
Norio Yamamoto, Kenji Tanigaki, Masayuki Tsuji, Daisuke Yabe, Juichi Ito, Tasuku Honjo. J Mol Med (Berl) 2006
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The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination.
Ping Chen, Jane E Johnson, Huda Y Zoghbi, Neil Segil. Development 2002
Ping Chen, Jane E Johnson, Huda Y Zoghbi, Neil Segil. Development 2002
13
Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification.
Joana Neves, Carolina Parada, Mireia Chamizo, Fernando Giráldez. Development 2011
Joana Neves, Carolina Parada, Mireia Chamizo, Fernando Giráldez. Development 2011
13
Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea.
Alain Dabdoub, Chandrakala Puligilla, Jennifer M Jones, Bernd Fritzsch, Kathryn S E Cheah, Larysa H Pevny, Matthew W Kelley. Proc Natl Acad Sci U S A 2008
Alain Dabdoub, Chandrakala Puligilla, Jennifer M Jones, Bernd Fritzsch, Kathryn S E Cheah, Larysa H Pevny, Matthew W Kelley. Proc Natl Acad Sci U S A 2008
13
Atoh1 expression defines activated progenitors and differentiating hair cells during avian hair cell regeneration.
Jon Cafaro, Gi Soo Lee, Jennifer S Stone. Dev Dyn 2007
Jon Cafaro, Gi Soo Lee, Jennifer S Stone. Dev Dyn 2007
13
Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea.
Soumya Korrapati, Isabelle Roux, Elisabeth Glowatzki, Angelika Doetzlhofer. PLoS One 2013
Soumya Korrapati, Isabelle Roux, Elisabeth Glowatzki, Angelika Doetzlhofer. PLoS One 2013
13
Sox2 is required for sensory organ development in the mammalian inner ear.
Amy E Kiernan, Anna L Pelling, Keith K H Leung, Anna S P Tang, Donald M Bell, Charles Tease, Robin Lovell-Badge, Karen P Steel, Kathryn S E Cheah. Nature 2005
Amy E Kiernan, Anna L Pelling, Keith K H Leung, Anna S P Tang, Donald M Bell, Charles Tease, Robin Lovell-Badge, Karen P Steel, Kathryn S E Cheah. Nature 2005
13
Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea.
Fu-Quan Chen, Jochen Schacht, Su-Hua Sha. J Neurochem 2009
Fu-Quan Chen, Jochen Schacht, Su-Hua Sha. J Neurochem 2009
13
siRNA targeting Hes5 augments hair cell regeneration in aminoglycoside-damaged mouse utricle.
Jae Yun Jung, Matt R Avenarius, Swetlana Adamsky, Evgenia Alpert, Elena Feinstein, Yehoash Raphael. Mol Ther 2013
Jae Yun Jung, Matt R Avenarius, Swetlana Adamsky, Evgenia Alpert, Elena Feinstein, Yehoash Raphael. Mol Ther 2013
13
Inhibition of H3K4me2 Demethylation Protects Auditory Hair Cells from Neomycin-Induced Apoptosis.
Yingzi He, Huiqian Yu, Chengfu Cai, Shan Sun, Renjie Chai, Huawei Li. Mol Neurobiol 2015
Yingzi He, Huiqian Yu, Chengfu Cai, Shan Sun, Renjie Chai, Huawei Li. Mol Neurobiol 2015
15
A bivalent chromatin structure marks key developmental genes in embryonic stem cells.
Bradley E Bernstein, Tarjei S Mikkelsen, Xiaohui Xie, Michael Kamal, Dana J Huebert, James Cuff, Ben Fry, Alex Meissner, Marius Wernig, Kathrin Plath,[...]. Cell 2006
Bradley E Bernstein, Tarjei S Mikkelsen, Xiaohui Xie, Michael Kamal, Dana J Huebert, James Cuff, Ben Fry, Alex Meissner, Marius Wernig, Kathrin Plath,[...]. Cell 2006
13
Histone methylation and acetylation indicates epigenetic change in the aged cochlea of mice.
Ken-Ichi Watanabe, Wilhelm Bloch. Eur Arch Otorhinolaryngol 2013
Ken-Ichi Watanabe, Wilhelm Bloch. Eur Arch Otorhinolaryngol 2013
27
Spontaneous Hair Cell Regeneration Is Prevented by Increased Notch Signaling in Supporting Cells.
Melissa M McGovern, Luyi Zhou, Michelle R Randle, Brandon C Cox. Front Cell Neurosci 2018
Melissa M McGovern, Luyi Zhou, Michelle R Randle, Brandon C Cox. Front Cell Neurosci 2018
21
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