A citation-based method for searching scientific literature

Tobias Eisenberg, Mahmoud Abdellatif, Sabrina Schroeder, Uwe Primessnig, Slaven Stekovic, Tobias Pendl, Alexandra Harger, Julia Schipke, Andreas Zimmermann, Albrecht Schmidt, Mingming Tong, Christoph Ruckenstuhl, Christopher Dammbrueck, Angelina S Gross, Viktoria Herbst, Christoph Magnes, Gert Trausinger, Sophie Narath, Andreas Meinitzer, Zehan Hu, Alexander Kirsch, Kathrin Eller, Didac Carmona-Gutierrez, Sabrina Büttner, Federico Pietrocola, Oskar Knittelfelder, Emilie Schrepfer, Patrick Rockenfeller, Corinna Simonini, Alexandros Rahn, Marion Horsch, Kristin Moreth, Johannes Beckers, Helmut Fuchs, Valerie Gailus-Durner, Frauke Neff, Dirk Janik, Birgit Rathkolb, Jan Rozman, Martin Hrabe de Angelis, Tarek Moustafa, Guenter Haemmerle, Manuel Mayr, Peter Willeit, Marion von Frieling-Salewsky, Burkert Pieske, Luca Scorrano, Thomas Pieber, Raimund Pechlaner, Johann Willeit, Stephan J Sigrist, Wolfgang A Linke, Christian Mühlfeld, Junichi Sadoshima, Joern Dengjel, Stefan Kiechl, Guido Kroemer, Simon Sedej, Frank Madeo. Nat Med 2016
Times Cited: 498







List of co-cited articles
1213 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Induction of autophagy by spermidine promotes longevity.
Tobias Eisenberg, Heide Knauer, Alexandra Schauer, Sabrina Büttner, Christoph Ruckenstuhl, Didac Carmona-Gutierrez, Julia Ring, Sabrina Schroeder, Christoph Magnes, Lucia Antonacci,[...]. Nat Cell Biol 2009
904
38

Spermidine in health and disease.
Frank Madeo, Tobias Eisenberg, Federico Pietrocola, Guido Kroemer. Science 2018
312
29

Higher spermidine intake is linked to lower mortality: a prospective population-based study.
Stefan Kiechl, Raimund Pechlaner, Peter Willeit, Marlene Notdurfter, Bernhard Paulweber, Karin Willeit, Philipp Werner, Christoph Ruckenstuhl, Bernhard Iglseder, Siegfried Weger,[...]. Am J Clin Nutr 2018
94
14

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
14

Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence.
Hanlin Zhang, Ghada Alsaleh, Jack Feltham, Yizhe Sun, Gennaro Napolitano, Thomas Riffelmacher, Philip Charles, Lisa Frau, Philip Hublitz, Zhanru Yu,[...]. Mol Cell 2019
82
17

Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential.
Frank Madeo, Didac Carmona-Gutierrez, Sebastian J Hofer, Guido Kroemer. Cell Metab 2019
196
11

Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner.
Varun K Gupta, Lisa Scheunemann, Tobias Eisenberg, Sara Mertel, Anuradha Bhukel, Tom S Koemans, Jamie M Kramer, Karen S Y Liu, Sabrina Schroeder, Hendrik G Stunnenberg,[...]. Nat Neurosci 2013
181
11

Functions of Polyamines in Mammals.
Anthony E Pegg. J Biol Chem 2016
264
10

The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial.
Miranka Wirth, Gloria Benson, Claudia Schwarz, Theresa Köbe, Ulrike Grittner, Dietmar Schmitz, Stephan J Sigrist, Jens Bohlken, Slaven Stekovic, Frank Madeo,[...]. Cortex 2018
46
19

Spermidine induces autophagy by inhibiting the acetyltransferase EP300.
F Pietrocola, S Lachkar, D P Enot, M Niso-Santano, J M Bravo-San Pedro, V Sica, V Izzo, M C Maiuri, F Madeo, G Mariño,[...]. Cell Death Differ 2015
151
9

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload-Induced Mitochondrial Dysfunction and Heart Failure.
Akihiro Shirakabe, Peiyong Zhai, Yoshiyuki Ikeda, Toshiro Saito, Yasuhiro Maejima, Chiao-Po Hsu, Masatoshi Nomura, Kensuke Egashira, Beth Levine, Junichi Sadoshima. Circulation 2016
227
9

Inhibition of autophagy in the heart induces age-related cardiomyopathy.
Manabu Taneike, Osamu Yamaguchi, Atsuko Nakai, Shungo Hikoso, Toshihiro Takeda, Isamu Mizote, Takafumi Oka, Takahito Tamai, Jota Oyabu, Tomokazu Murakawa,[...]. Autophagy 2010
289
9

Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline.
Claudia Schwarz, Slaven Stekovic, Miranka Wirth, Gloria Benson, Philipp Royer, Stephan J Sigrist, Thomas Pieber, Christopher Dammbrueck, Christoph Magnes, Tobias Eisenberg,[...]. Aging (Albany NY) 2018
52
17

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
9

Spermidine Prolongs Lifespan and Prevents Liver Fibrosis and Hepatocellular Carcinoma by Activating MAP1S-Mediated Autophagy.
Fei Yue, Wenjiao Li, Jing Zou, Xianhan Jiang, Guibin Xu, Hai Huang, Leyuan Liu. Cancer Res 2017
84
9

Long-term oral polyamine intake increases blood polyamine concentrations.
Kuniyasu Soda, Yoshihiko Kano, Masako Sakuragi, Koichi Takao, Alan Lefor, Fumio Konishi. J Nutr Sci Vitaminol (Tokyo) 2009
76
10

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
8

Polyamine-rich food decreases age-associated pathology and mortality in aged mice.
Kuniyasu Soda, Yoh Dobashi, Yoshihiko Kano, Shingo Tsujinaka, Fumio Konishi. Exp Gerontol 2009
109
8

Aging and Autophagy in the Heart.
Akihiro Shirakabe, Yoshiyuki Ikeda, Sebastiano Sciarretta, Daniela K Zablocki, Junichi Sadoshima. Circ Res 2016
221
8

Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice.
Álvaro F Fernández, Salwa Sebti, Yongjie Wei, Zhongju Zou, Mingjun Shi, Kathryn L McMillan, Congcong He, Tabitha Ting, Yang Liu, Wei-Chung Chiang,[...]. Nature 2018
261
8

Measuring In Vivo Mitophagy.
Nuo Sun, Jeanho Yun, Jie Liu, Daniela Malide, Chengyu Liu, Ilsa I Rovira, Kira M Holmström, Maria M Fergusson, Young Hyun Yoo, Christian A Combs,[...]. Mol Cell 2015
353
8

An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia.
Toshiro Saito, Jihoon Nah, Shin-Ichi Oka, Risa Mukai, Yoshiya Monden, Yasuhiro Maejima, Yoshiyuki Ikeda, Sebastiano Sciarretta, Tong Liu, Hong Li,[...]. J Clin Invest 2019
109
8

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
David E Harrison, Randy Strong, Zelton Dave Sharp, James F Nelson, Clinton M Astle, Kevin Flurkey, Nancy L Nadon, J Erby Wilkinson, Krystyna Frenkel, Christy S Carter,[...]. Nature 2009
8

Overexpression of Atg5 in mice activates autophagy and extends lifespan.
Jong-Ok Pyo, Seung-Min Yoo, Hye-Hyun Ahn, Jihoon Nah, Se-Hoon Hong, Tae-In Kam, Sunmin Jung, Yong-Keun Jung. Nat Commun 2013
388
8

Upregulation of colonic luminal polyamines produced by intestinal microbiota delays senescence in mice.
Ryoko Kibe, Shin Kurihara, Yumi Sakai, Hideyuki Suzuki, Takushi Ooga, Emiko Sawaki, Koji Muramatsu, Atsuo Nakamura, Ayano Yamashita, Yusuke Kitada,[...]. Sci Rep 2014
128
8

Autophagy and Mitophagy in Cardiovascular Disease.
José Manuel Bravo-San Pedro, Guido Kroemer, Lorenzo Galluzzi. Circ Res 2017
281
7

Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart.
Atsushi Hoshino, Yuichiro Mita, Yoshifumi Okawa, Makoto Ariyoshi, Eri Iwai-Kanai, Tomomi Ueyama, Koji Ikeda, Takehiro Ogata, Satoaki Matoba. Nat Commun 2013
299
7

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress.
Atsuko Nakai, Osamu Yamaguchi, Toshihiro Takeda, Yoshiharu Higuchi, Shungo Hikoso, Masayuki Taniike, Shigemiki Omiya, Isamu Mizote, Yasushi Matsumura, Michio Asahi,[...]. Nat Med 2007
7

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.
Daniel F Egan, David B Shackelford, Maria M Mihaylova, Sara Gelino, Rebecca A Kohnz, William Mair, Debbie S Vasquez, Aashish Joshi, Dana M Gwinn, Rebecca Taylor,[...]. Science 2011
7

Autophagy and aging.
David C Rubinsztein, Guillermo Mariño, Guido Kroemer. Cell 2011
7

The Mitochondrial Basis of Aging.
Nuo Sun, Richard J Youle, Toren Finkel. Mol Cell 2016
577
7

Mammalian polyamine metabolism and function.
Anthony E Pegg. IUBMB Life 2009
431
7

Metformin as a Tool to Target Aging.
Nir Barzilai, Jill P Crandall, Stephen B Kritchevsky, Mark A Espeland. Cell Metab 2016
464
7

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents.
Dongryeol Ryu, Laurent Mouchiroud, Pénélope A Andreux, Elena Katsyuba, Norman Moullan, Amandine A Nicolet-Dit-Félix, Evan G Williams, Pooja Jha, Giuseppe Lo Sasso, Damien Huzard,[...]. Nat Med 2016
393
7

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance.
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
668
7

Resveratrol improves health and survival of mice on a high-calorie diet.
Joseph A Baur, Kevin J Pearson, Nathan L Price, Hamish A Jamieson, Carles Lerin, Avash Kalra, Vinayakumar V Prabhu, Joanne S Allard, Guillermo Lopez-Lluch, Kaitlyn Lewis,[...]. Nature 2006
7

Caloric restriction mimetics: towards a molecular definition.
Frank Madeo, Federico Pietrocola, Tobias Eisenberg, Guido Kroemer. Nat Rev Drug Discov 2014
141
6

Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart.
Dao-Fu Dai, Pabalu P Karunadharma, Ying A Chiao, Nathan Basisty, David Crispin, Edward J Hsieh, Tony Chen, Haiwei Gu, Danijel Djukovic, Daniel Raftery,[...]. Aging Cell 2014
178
6

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.
Ryan C Russell, Ye Tian, Haixin Yuan, Hyun Woo Park, Yu-Yun Chang, Joungmok Kim, Haerin Kim, Thomas P Neufeld, Andrew Dillin, Kun-Liang Guan. Nat Cell Biol 2013
924
6

AMPKα2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation.
Bei Wang, Jiali Nie, Lujin Wu, Yangyang Hu, Zheng Wen, Lingli Dong, Ming-Hui Zou, Chen Chen, Dao Wen Wang. Circ Res 2018
122
6

Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome.
Eugenia Morselli, Guillermo Mariño, Martin V Bennetzen, Tobias Eisenberg, Evgenia Megalou, Sabrina Schroeder, Sandra Cabrera, Paule Bénit, Pierre Rustin, Alfredo Criollo,[...]. J Cell Biol 2011
322
6

Spermidine: a novel autophagy inducer and longevity elixir.
Frank Madeo, Tobias Eisenberg, Sabrina Büttner, Christoph Ruckenstuhl, Guido Kroemer. Autophagy 2010
113
6

Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?
Frank Madeo, Maria A Bauer, Didac Carmona-Gutierrez, Guido Kroemer. Autophagy 2019
52
11

Polyamine metabolism and cancer: treatments, challenges and opportunities.
Robert A Casero, Tracy Murray Stewart, Anthony E Pegg. Nat Rev Cancer 2018
218
6

Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice.
Guohua Gong, Moshi Song, Gyorgy Csordas, Daniel P Kelly, Scot J Matkovich, Gerald W Dorn. Science 2015
248
6

Autophagy genes are essential for dauer development and life-span extension in C. elegans.
Alicia Meléndez, Zsolt Tallóczy, Matthew Seaman, Eeva-Liisa Eskelinen, David H Hall, Beth Levine. Science 2003
934
6

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.
Daniel J Puleston, Michael D Buck, Ramon I Klein Geltink, Ryan L Kyle, George Caputa, David O'Sullivan, Alanna M Cameron, Angela Castoldi, Yaarub Musa, Agnieszka M Kabat,[...]. Cell Metab 2019
105
6



PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.