A citation-based method for searching scientific literature

Melanie J Ludlow, Hannah J Gaunt, Hussein N Rubaiy, Katie E Musialowski, Nicola M Blythe, Naveen S Vasudev, Katsuhiko Muraki, David J Beech. J Biol Chem 2017
Times Cited: 25







List of co-cited articles
217 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


(-)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels.
Yasemin Akbulut, Hannah J Gaunt, Katsuhiko Muraki, Melanie J Ludlow, Mohamed S Amer, Alexander Bruns, Naveen S Vasudev, Lea Radtke, Matthieu Willot, Sven Hahn,[...]. Angew Chem Int Ed Engl 2015
115
76

Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation.
Cheryl Carson, Pichai Raman, Jennifer Tullai, Lei Xu, Martin Henault, Emily Thomas, Sarita Yeola, Jianmin Lao, Mark McPate, J Martin Verkuyl,[...]. PLoS One 2015
59
72

Englerin A, a selective inhibitor of renal cancer cell growth, from Phyllanthus engleri.
Ranjala Ratnayake, David Covell, Tanya T Ransom, Kirk R Gustafson, John A Beutler. Org Lett 2009
118
52

Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.
Hussein N Rubaiy, Melanie J Ludlow, Matthias Henrot, Hannah J Gaunt, Katarina Miteva, Sin Ying Cheung, Yasuyuki Tanahashi, Nurasyikin Hamzah, Katie E Musialowski, Nicola M Blythe,[...]. J Biol Chem 2017
46
52

Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
Melissa Miller, Jie Shi, Yingmin Zhu, Maksym Kustov, Jin-bin Tian, Amy Stevens, Meng Wu, Jia Xu, Shunyou Long, Pu Yang,[...]. J Biol Chem 2011
133
44

Essential role for TRPC5 in amygdala function and fear-related behavior.
Antonio Riccio, Yan Li, Jisook Moon, Kwang-Soo Kim, Kiersten S Smith, Uwe Rudolph, Svetlana Gapon, Gui Lan Yao, Evgeny Tsvetkov, Scott J Rodig,[...]. Cell 2009
178
44

Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality.
Carole Sourbier, Bradley T Scroggins, Ranjala Ratnayake, Thomas L Prince, Sunmin Lee, Min-Jung Lee, Peter Literati Nagy, Young H Lee, Jane B Trepel, John A Beutler,[...]. Cancer Cell 2013
55
40

Transient receptor potential canonical 4 and 5 proteins as targets in cancer therapeutics.
Hannah J Gaunt, Naveen S Vasudev, David J Beech. Eur Biophys J 2016
26
40

Englerins: A Comprehensive Review.
Zhenhua Wu, Senzhi Zhao, David M Fash, Zhenwu Li, William J Chain, John A Beutler. J Nat Prod 2017
21
47

Na+ entry through heteromeric TRPC4/C1 channels mediates (-)Englerin A-induced cytotoxicity in synovial sarcoma cells.
Katsuhiko Muraki, Kaori Ohnishi, Akiho Takezawa, Hiroka Suzuki, Noriyuki Hatano, Yukiko Muraki, Nurasyikin Hamzah, Richard Foster, Herbert Waldmann, Peter Nussbaumer,[...]. Sci Rep 2017
20
50

Transient receptor potential channel 1 (TRPC1) reduces calcium permeability in heteromeric channel complexes.
Ursula Storch, Anna-Lena Forst, Maximilian Philipp, Thomas Gudermann, Michael Mederos y Schnitzler. J Biol Chem 2012
101
36

Natural and synthetic flavonoid modulation of TRPC5 channels.
Jacqueline Naylor, Aisling Minard, Hannah J Gaunt, Mohamed S Amer, Lesley A Wilson, Marco Migliore, Sin Y Cheung, Hussein N Rubaiy, Nicola M Blythe, Katie E Musialowski,[...]. Br J Pharmacol 2016
24
33

Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels.
Antonio Riccio, Yan Li, Evgeny Tsvetkov, Svetlana Gapon, Gui Lan Yao, Kiersten S Smith, Elif Engin, Uwe Rudolph, Vadim Y Bolshakov, David E Clapham. J Neurosci 2014
57
32

Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms.
Kevin D Phelan, U Thaung Shwe, Joel Abramowitz, Hong Wu, Sung W Rhee, Matthew D Howell, Paul E Gottschall, Marc Freichel, Veit Flockerzi, Lutz Birnbaumer,[...]. Mol Pharmacol 2013
83
32

Identification of an (-)-englerin A analogue, which antagonizes (-)-englerin A at TRPC1/4/5 channels.
Hussein N Rubaiy, Tobias Seitz, Sven Hahn, Axel Choidas, Peter Habenberger, Bert Klebl, Klaus Dinkel, Peter Nussbaumer, Herbert Waldmann, Mathias Christmann,[...]. Br J Pharmacol 2018
11
72

Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice.
Stefan Just, Bertrand L Chenard, Angelo Ceci, Timothy Strassmaier, Jayhong A Chong, Nathaniel T Blair, Randall J Gallaschun, Donato Del Camino, Susan Cantin, Marc D'Amours,[...]. PLoS One 2018
45
32

Electron cryo-microscopy structure of the canonical TRPC4 ion channel.
Deivanayagabarathy Vinayagam, Thomas Mager, Amir Apelbaum, Arne Bothe, Felipe Merino, Oliver Hofnagel, Christos Gatsogiannis, Stefan Raunser. Elife 2018
60
32



TRPC1 and TRPC5 form a novel cation channel in mammalian brain.
C Strübing, G Krapivinsky, L Krapivinsky, D E Clapham. Neuron 2001
586
28

A rat knockout model implicates TRPC4 in visceral pain sensation.
K N Westlund, L P Zhang, F Ma, R Nesemeier, J C Ruiz, E M Ostertag, J S Crawford, K Babinski, M M Marcinkiewicz. Neuroscience 2014
24
29


Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.
Jenny Bröker-Lai, Astrid Kollewe, Barbara Schindeldecker, Jörg Pohle, Vivan Nguyen Chi, Ilka Mathar, Raul Guzman, Yvonne Schwarz, Alan Lai, Petra Weißgerber,[...]. EMBO J 2017
64
28

Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profile.
Lea Radtke, Matthieu Willot, Hongyan Sun, Slava Ziegler, Stephanie Sauerland, Carsten Strohmann, Roland Fröhlich, Peter Habenberger, Herbert Waldmann, Mathias Christmann. Angew Chem Int Ed Engl 2011
48
24

Englerin A Inhibits EWS-FLI1 DNA Binding in Ewing Sarcoma Cells.
Vittorio Caropreso, Emad Darvishi, Thomas J Turbyville, Ranjala Ratnayake, Patrick J Grohar, James B McMahon, Girma M Woldemichael. J Biol Chem 2016
21
28

Unveiling (-)-Englerin A as a Modulator of L-Type Calcium Channels.
Tiago Rodrigues, Florian Sieglitz, Víctor J Somovilla, Pedro M S D Cal, Antony Galione, Francisco Corzana, Gonçalo J L Bernardes. Angew Chem Int Ed Engl 2016
24
25

TRPC channel activation by extracellular thioredoxin.
Shang-Zhong Xu, Piruthivi Sukumar, Fanning Zeng, Jing Li, Amit Jairaman, Anne English, Jacqueline Naylor, Coziana Ciurtin, Yasser Majeed, Carol J Milligan,[...]. Nature 2008
203
24

Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels.
Yingmin Zhu, Yungang Lu, Chunrong Qu, Melissa Miller, Jinbin Tian, Dhananjay P Thakur, Jinmei Zhu, Zixin Deng, Xianming Hu, Meng Wu,[...]. Br J Pharmacol 2015
26
24


Riluzole activates TRPC5 channels independently of PLC activity.
Julia M Richter, Michael Schaefer, Kerstin Hill. Br J Pharmacol 2014
29
24

Subunit composition of mammalian transient receptor potential channels in living cells.
Thomas Hofmann, Michael Schaefer, Günter Schultz, Thomas Gudermann. Proc Natl Acad Sci U S A 2002
571
24

Pico145 - powerful new tool for TRPC1/4/5 channels.
Hussein N Rubaiy, Melanie J Ludlow, Robin S Bon, David J Beech. Channels (Austin) 2017
19
31

Structure of the mouse TRPC4 ion channel.
Jingjing Duan, Jian Li, Bo Zeng, Gui-Lan Chen, Xiaogang Peng, Yixing Zhang, Jianbin Wang, David E Clapham, Zongli Li, Jin Zhang. Nat Commun 2018
60
24

Inhibition of the TRPC5 ion channel protects the kidney filter.
Thomas Schaldecker, Sookyung Kim, Constantine Tarabanis, Dequan Tian, Samy Hakroush, Philip Castonguay, Wooin Ahn, Hanna Wallentin, Hans Heid, Corey R Hopkins,[...]. J Clin Invest 2013
109
20

A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling.
Juan E Camacho Londoño, Qinghai Tian, Karin Hammer, Laura Schröder, Julia Camacho Londoño, Jan C Reil, Tao He, Martin Oberhofer, Stefanie Mannebach, Ilka Mathar,[...]. Eur Heart J 2015
67
20


TRPC1, a human homolog of a Drosophila store-operated channel.
P D Wes, J Chevesich, A Jeromin, C Rosenberg, G Stetten, C Montell. Proc Natl Acad Sci U S A 1995
467
20

Lanthanides potentiate TRPC5 currents by an action at extracellular sites close to the pore mouth.
Silke Jung, Anja Mühle, Michael Schaefer, Rainer Strotmann, Gunter Schultz, Tim D Plant. J Biol Chem 2003
205
20

TRPC5 channels participate in pressure-sensing in aortic baroreceptors.
On-Chai Lau, Bing Shen, Ching-On Wong, Yung-Wui Tjong, Chun-Yin Lo, Hui-Chuan Wang, Yu Huang, Wing-Ho Yung, Yang-Chao Chen, Man-Lung Fung,[...]. Nat Commun 2016
36
20

Receptor-mediated regulation of the nonselective cation channels TRPC4 and TRPC5.
M Schaefer, T D Plant, A G Obukhov, T Hofmann, T Gudermann, G Schultz. J Biol Chem 2000
330
20

Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice.
Li-Ping Yang, Fang-Jie Jiang, Gui-Sheng Wu, Ke Deng, Meng Wen, Xiaoju Zhou, Xuechuan Hong, Michael X Zhu, Huai-Rong Luo. PLoS One 2015
28
20

Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo.
Volodymyr V Tsvilovskyy, Alexander V Zholos, Thomas Aberle, Stephan E Philipp, Alexander Dietrich, Michael X Zhu, Lutz Birnbaumer, Marc Freichel, Veit Flockerzi. Gastroenterology 2009
119
20

Transient receptor potential channel TRPC5 is essential for P-glycoprotein induction in drug-resistant cancer cells.
Xin Ma, Yanfei Cai, Dongxu He, Chang Zou, Peng Zhang, Chun Yin Lo, Zhenyu Xu, Franky L Chan, Shan Yu, Yun Chen,[...]. Proc Natl Acad Sci U S A 2012
99
20

TRP channels as cellular sensors.
David E Clapham. Nature 2003
20

A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models.
Yiming Zhou, Philip Castonguay, Eriene-Heidi Sidhom, Abbe R Clark, Moran Dvela-Levitt, Sookyung Kim, Jonas Sieber, Nicolas Wieder, Ji Yong Jung, Svetlana Andreeva,[...]. Science 2017
74
20

Enantioselective synthesis of (-)-englerins A and B.
Kian Molawi, Nicolas Delpont, Antonio M Echavarren. Angew Chem Int Ed Engl 2010
105
16

Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent.
Carole Sourbier, Bradley T Scroggins, Philip Z Mannes, Pei-Jyun Liao, Karsten Siems, Dietmar Wolf, John A Beutler, W Marston Linehan, Leonard Neckers. Oncotarget 2015
12
33

Total synthesis of englerin A.
K C Nicolaou, Qiang Kang, Sin Yee Ng, David Y-K Chen. J Am Chem Soc 2010
76
16

Englerin a selectively induces necrosis in human renal cancer cells.
Florian J Sulzmaier, Zhenwu Li, Mika L Nakashige, David M Fash, William J Chain, Joe W Ramos. PLoS One 2012
23
17

Regulation of neuropathic pain behavior by amygdaloid TRPC4/C5 channels.
Hong Wei, Boriss Sagalajev, M Anil Yüzer, Ari Koivisto, Antti Pertovaara. Neurosci Lett 2015
18
22


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.