A citation-based method for searching scientific literature

Jon C Aster, Warren S Pear, Stephen C Blacklow. Annu Rev Pathol 2017
Times Cited: 280







List of co-cited articles
882 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Notch signalling in context.
Sarah J Bray. Nat Rev Mol Cell Biol 2016
479
17

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
16

Notch Signaling in Development, Tissue Homeostasis, and Disease.
Chris Siebel, Urban Lendahl. Physiol Rev 2017
352
12

The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.
Rhett A Kovall, Brian Gebelein, David Sprinzak, Raphael Kopan. Dev Cell 2017
168
10

Notch as a tumour suppressor.
Craig S Nowell, Freddy Radtke. Nat Rev Cancer 2017
192
10

Notch Signaling in the Tumor Microenvironment.
Olivier Meurette, Patrick Mehlen. Cancer Cell 2018
196
9

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.
Nicholas J Wang, Zachary Sanborn, Kelly L Arnett, Laura J Bayston, Wilson Liao, Charlotte M Proby, Irene M Leigh, Eric A Collisson, Patricia B Gordon, Lakshmi Jakkula,[...]. Proc Natl Acad Sci U S A 2011
312
9

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
9

Therapeutic modulation of Notch signalling--are we there yet?
Emma R Andersson, Urban Lendahl. Nat Rev Drug Discov 2014
314
9

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE.
C Brou, F Logeat, N Gupta, C Bessia, O LeBail, J R Doedens, A Cumano, P Roux, R A Black, A Israël. Mol Cell 2000
840
9

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
9

Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update.
Naoko Takebe, Lucio Miele, Pamela Jo Harris, Woondong Jeong, Hideaki Bando, Michael Kahn, Sherry X Yang, S Percy Ivy. Nat Rev Clin Oncol 2015
735
8

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1.
Nishant Agrawal, Mitchell J Frederick, Curtis R Pickering, Chetan Bettegowda, Kyle Chang, Ryan J Li, Carole Fakhry, Tong-Xin Xie, Jiexin Zhang, Jing Wang,[...]. Science 2011
8

A new tumor suppressor role for the Notch pathway in bladder cancer.
Theodoros Rampias, Paraskevi Vgenopoulou, Margaritis Avgeris, Alexander Polyzos, Konstantinos Stravodimos, Christos Valavanis, Andreas Scorilas, Apostolos Klinakis. Nat Med 2014
121
8

Notch signaling: cell fate control and signal integration in development.
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
8

The mutational landscape of head and neck squamous cell carcinoma.
Nicolas Stransky, Ann Marie Egloff, Aaron D Tward, Aleksandar D Kostic, Kristian Cibulskis, Andrey Sivachenko, Gregory V Kryukov, Michael S Lawrence, Carrie Sougnez, Aaron McKenna,[...]. Science 2011
7

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.
L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
7

Cis-activation in the Notch signaling pathway.
Nagarajan Nandagopal, Leah A Santat, Michael B Elowitz. Elife 2019
31
22

Therapeutic antibody targeting of individual Notch receptors.
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
516
7

Structural basis for autoinhibition of Notch.
Wendy R Gordon, Didem Vardar-Ulu, Gavin Histen, Cheryll Sanchez-Irizarry, Jon C Aster, Stephen C Blacklow. Nat Struct Mol Biol 2007
236
7

Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch.
Wendy R Gordon, Brandon Zimmerman, Li He, Laura J Miles, Jiuhong Huang, Kittichoat Tiyanont, Debbie G McArthur, Jon C Aster, Norbert Perrimon, Joseph J Loparo,[...]. Dev Cell 2015
165
7

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.
L Wu, J C Aster, S C Blacklow, R Lake, S Artavanis-Tsakonas, J D Griffin. Nat Genet 2000
441
7

Notch signaling: simplicity in design, versatility in function.
Emma R Andersson, Rickard Sandberg, Urban Lendahl. Development 2011
617
7

A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition.
Jemima Cordle, Steven Johnson, Joyce Zi Yan Tay, Pietro Roversi, Marian B Wilkin, Beatriz Hernández de Madrid, Hideyuki Shimizu, Sacha Jensen, Pat Whiteman, Boquan Jin,[...]. Nat Struct Mol Biol 2008
173
7

Ligand endocytosis drives receptor dissociation and activation in the Notch pathway.
A L Parks, K M Klueg, J R Stout, M A Muskavitch. Development 2000
376
7

Notch signalling: a simple pathway becomes complex.
Sarah J Bray. Nat Rev Mol Cell Biol 2006
7

Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.
Patrick Viatour, Ursula Ehmer, Louis A Saddic, Craig Dorrell, Jesper B Andersen, Chenwei Lin, Anne-Flore Zmoos, Pawel K Mazur, Bethany E Schaffer, Austin Ostermeier,[...]. J Exp Med 2011
141
6

PEST domain mutations in Notch receptors comprise an oncogenic driver segment in triple-negative breast cancer sensitive to a γ-secretase inhibitor.
Kai Wang, Qin Zhang, Danan Li, Keith Ching, Cathy Zhang, Xianxian Zheng, Mark Ozeck, Stephanie Shi, Xiaorong Li, Hui Wang,[...]. Clin Cancer Res 2015
91
6


Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition.
Roger A Habets, Charles E de Bock, Lutgarde Serneels, Inge Lodewijckx, Delphine Verbeke, David Nittner, Rajeshwar Narlawar, Sofie Demeyer, James Dooley, Adrian Liston,[...]. Sci Transl Med 2019
47
12

Structural biology. Structural basis for Notch1 engagement of Delta-like 4.
Vincent C Luca, Kevin M Jude, Nathan W Pierce, Maxence V Nachury, Suzanne Fischer, K Christopher Garcia. Science 2015
151
6

Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency.
Wan-Ching Yen, Marcus M Fischer, Fumiko Axelrod, Christopher Bond, Jennifer Cain, Belinda Cancilla, William R Henner, Rene Meisner, Aaron Sato, Jalpa Shah,[...]. Clin Cancer Res 2015
162
6

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
660
6

A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors.
Elena Gabriela Chiorean, Patricia LoRusso, Robert Matthew Strother, Jennifer R Diamond, Anne Younger, Wells A Messersmith, Lieve Adriaens, Liming Liu, Richard J Kao, Albert Thomas DiCioccio,[...]. Clin Cancer Res 2015
79
7

First-in-human study of LY3039478, an oral Notch signaling inhibitor in advanced or metastatic cancer.
C Massard, A Azaro, J-C Soria, U Lassen, C Le Tourneau, D Sarker, C Smith, U Ohnmacht, G Oakley, B K R Patel,[...]. Ann Oncol 2018
61
9

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.
Dan R Robinson, Shanker Kalyana-Sundaram, Yi-Mi Wu, Sunita Shankar, Xuhong Cao, Bushra Ateeq, Irfan A Asangani, Matthew Iyer, Christopher A Maher, Catherine S Grasso,[...]. Nat Med 2011
241
6

Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
P Bernasconi-Elias, T Hu, D Jenkins, B Firestone, S Gans, E Kurth, P Capodieci, J Deplazes-Lauber, K Petropoulos, P Thiel,[...]. Oncogene 2016
53
11

Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy.
Hanqiu Zheng, Yangjin Bae, Sabine Kasimir-Bauer, Rebecca Tang, Jin Chen, Guangwen Ren, Min Yuan, Mark Esposito, Wenyang Li, Yong Wei,[...]. Cancer Cell 2017
82
7

Fringe is a glycosyltransferase that modifies Notch.
D J Moloney, V M Panin, S H Johnston, J Chen, L Shao, R Wilson, Y Wang, P Stanley, K D Irvine, R S Haltiwanger,[...]. Nature 2000
662
6

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1.
J S Mumm, E H Schroeter, M T Saxena, A Griesemer, X Tian, D J Pan, W J Ray, R Kopan. Mol Cell 2000
654
6

Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin.
Laurence Meloty-Kapella, Bhupinder Shergill, Jane Kuon, Elliot Botvinick, Gerry Weinmaster. Dev Cell 2012
148
6

DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur.
James T Nichols, Alison Miyamoto, Samantha L Olsen, Brendan D'Souza, Christine Yao, Gerry Weinmaster. J Cell Biol 2007
176
6

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
Yunsun Nam, Piotr Sliz, Luyan Song, Jon C Aster, Stephen C Blacklow. Cell 2006
317
6

The Notch1 receptor is cleaved constitutively by a furin-like convertase.
F Logeat, C Bessia, C Brou, O LeBail, S Jarriault, N G Seidah, A Israël. Proc Natl Acad Sci U S A 1998
544
6

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival.
Michael Reedijk, Silvia Odorcic, Lynn Chang, Hui Zhang, Naomi Miller, David R McCready, Gina Lockwood, Sean E Egan. Cancer Res 2005
560
6

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources.
Da Wei Huang, Brad T Sherman, Richard A Lempicki. Nat Protoc 2009
6

Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells.
Gabriela Dontu, Kyle W Jackson, Erin McNicholas, Mari J Kawamura, Wissam M Abdallah, Max S Wicha. Breast Cancer Res 2004
540
6

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data.
Ethan Cerami, Jianjiong Gao, Ugur Dogrusoz, Benjamin E Gross, Selcuk Onur Sumer, Bülent Arman Aksoy, Anders Jacobsen, Caitlin J Byrne, Michael L Heuer, Erik Larsson,[...]. Cancer Discov 2012
6



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.