Wanil Kim, Andrew T Ludlow, Jaewon Min, Jerome D Robin, Guido Stadler, Ilgen Mender, Tsung-Po Lai, Ning Zhang, Woodring E Wright, Jerry W Shay. PLoS Biol 2016
Times Cited: 93
Times Cited: 93
Times Cited
Times Co-cited
Similarity
Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances.
Jérôme D Robin, Andrew T Ludlow, Kimberly Batten, Frédérique Magdinier, Guido Stadler, Kathyrin R Wagner, Jerry W Shay, Woodring E Wright. Genes Dev 2014
Jérôme D Robin, Andrew T Ludlow, Kimberly Batten, Frédérique Magdinier, Guido Stadler, Kathyrin R Wagner, Jerry W Shay, Woodring E Wright. Genes Dev 2014
45
Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
Titia de Lange. Genes Dev 2005
34
Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
29
24
TERT promoter mutations in familial and sporadic melanoma.
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
24
Highly recurrent TERT promoter mutations in human melanoma.
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
23
Alternative splicing regulation of telomerase: a new paradigm?
Mandy S Wong, Woodring E Wright, Jerry W Shay. Trends Genet 2014
Mandy S Wong, Woodring E Wright, Jerry W Shay. Trends Genet 2014
33
Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
22
Systematic analysis of telomere length and somatic alterations in 31 cancer types.
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
21
SORBS2 transcription is activated by telomere position effect-over long distance upon telomere shortening in muscle cells from patients with facioscapulohumeral dystrophy.
Jérôme D Robin, Andrew T Ludlow, Kimberly Batten, Marie-Cécile Gaillard, Guido Stadler, Frédérique Magdinier, Woodring E Wright, Jerry W Shay. Genome Res 2015
Jérôme D Robin, Andrew T Ludlow, Kimberly Batten, Marie-Cécile Gaillard, Guido Stadler, Frédérique Magdinier, Woodring E Wright, Jerry W Shay. Genome Res 2015
38
19
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.
Claus M Azzalin, Patrick Reichenbach, Lela Khoriauli, Elena Giulotto, Joachim Lingner. Science 2007
Claus M Azzalin, Patrick Reichenbach, Lela Khoriauli, Elena Giulotto, Joachim Lingner. Science 2007
18
18
Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.
Robert J A Bell, H Tomas Rube, Alex Kreig, Andrew Mancini, Shaun D Fouse, Raman P Nagarajan, Serah Choi, Chibo Hong, Daniel He, Melike Pekmezci,[...]. Science 2015
Robert J A Bell, H Tomas Rube, Alex Kreig, Andrew Mancini, Shaun D Fouse, Raman P Nagarajan, Serah Choi, Chibo Hong, Daniel He, Melike Pekmezci,[...]. Science 2015
18
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
C W Greider, E H Blackburn. Cell 1985
C W Greider, E H Blackburn. Cell 1985
17
Frequency of TERT promoter mutations in human cancers.
João Vinagre, Ana Almeida, Helena Pópulo, Rui Batista, Joana Lyra, Vasco Pinto, Ricardo Coelho, Ricardo Celestino, Hugo Prazeres, Luis Lima,[...]. Nat Commun 2013
João Vinagre, Ana Almeida, Helena Pópulo, Rui Batista, Joana Lyra, Vasco Pinto, Ricardo Coelho, Ricardo Celestino, Hugo Prazeres, Luis Lima,[...]. Nat Commun 2013
17
Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers.
Josh Lewis Stern, Dan Theodorescu, Bert Vogelstein, Nickolas Papadopoulos, Thomas R Cech. Genes Dev 2015
Josh Lewis Stern, Dan Theodorescu, Bert Vogelstein, Nickolas Papadopoulos, Thomas R Cech. Genes Dev 2015
17
Long-range telomere regulation of gene expression: Telomere looping and telomere position effect over long distances (TPE-OLD).
Wanil Kim, Jerry W Shay. Differentiation 2018
Wanil Kim, Jerry W Shay. Differentiation 2018
51
Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
16
Telomere length regulates ISG15 expression in human cells.
Zhenjun Lou, Jun Wei, Harold Riethman, Joseph A Baur, Regina Voglauer, Jerry W Shay, Woodring E Wright. Aging (Albany NY) 2009
Zhenjun Lou, Jun Wei, Harold Riethman, Joseph A Baur, Regina Voglauer, Jerry W Shay, Woodring E Wright. Aging (Albany NY) 2009
22
Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
C B Harley, A B Futcher, C W Greider. Nature 1990
16
16
Telomeres and telomerase: three decades of progress.
Jerry W Shay, Woodring E Wright. Nat Rev Genet 2019
Jerry W Shay, Woodring E Wright. Nat Rev Genet 2019
16
TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres.
Zhong Deng, Julie Norseen, Andreas Wiedmer, Harold Riethman, Paul M Lieberman. Mol Cell 2009
Zhong Deng, Julie Norseen, Andreas Wiedmer, Harold Riethman, Paul M Lieberman. Mol Cell 2009
15
TRF2 protects human telomeres from end-to-end fusions.
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
15
The human TTAGGG repeat factors 1 and 2 bind to a subset of interstitial telomeric sequences and satellite repeats.
Thomas Simonet, Laure-Emmanuelle Zaragosi, Claude Philippe, Kevin Lebrigand, Clémentine Schouteden, Adeline Augereau, Serge Bauwens, Jing Ye, Marco Santagostino, Elena Giulotto,[...]. Cell Res 2011
Thomas Simonet, Laure-Emmanuelle Zaragosi, Claude Philippe, Kevin Lebrigand, Clémentine Schouteden, Adeline Augereau, Serge Bauwens, Jing Ye, Marco Santagostino, Elena Giulotto,[...]. Cell Res 2011
15
TRF2 and lamin A/C interact to facilitate the functional organization of chromosome ends.
Ashley M Wood, Jannie M Rendtlew Danielsen, Catherine A Lucas, Ellen L Rice, David Scalzo, Takeshi Shimi, Robert D Goldman, Erica D Smith, Michelle M Le Beau, Steven T Kosak. Nat Commun 2014
Ashley M Wood, Jannie M Rendtlew Danielsen, Catherine A Lucas, Ellen L Rice, David Scalzo, Takeshi Shimi, Robert D Goldman, Erica D Smith, Michelle M Le Beau, Steven T Kosak. Nat Commun 2014
17
Telomere position effect regulates DUX4 in human facioscapulohumeral muscular dystrophy.
Guido Stadler, Fedik Rahimov, Oliver D King, Jennifer C J Chen, Jerome D Robin, Kathryn R Wagner, Jerry W Shay, Charles P Emerson, Woodring E Wright. Nat Struct Mol Biol 2013
Guido Stadler, Fedik Rahimov, Oliver D King, Jennifer C J Chen, Jerome D Robin, Kathryn R Wagner, Jerry W Shay, Charles P Emerson, Woodring E Wright. Nat Struct Mol Biol 2013
21
The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
15
Alternatively spliced telomerase reverse transcriptase variants lacking telomerase activity stimulate cell proliferation.
Radmila Hrdlicková, Jirí Nehyba, Henry R Bose. Mol Cell Biol 2012
Radmila Hrdlicková, Jirí Nehyba, Henry R Bose. Mol Cell Biol 2012
16
Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription.
D E Gottschling, O M Aparicio, B L Billington, V A Zakian. Cell 1990
D E Gottschling, O M Aparicio, B L Billington, V A Zakian. Cell 1990
13
Telomerase activity in human germline and embryonic tissues and cells.
W E Wright, M A Piatyszek, W E Rainey, W Byrd, J W Shay. Dev Genet 1996
W E Wright, M A Piatyszek, W E Rainey, W Byrd, J W Shay. Dev Genet 1996
13
A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.
R K Moyzis, J M Buckingham, L S Cram, M Dani, L L Deaven, M D Jones, J Meyne, R L Ratliff, J R Wu. Proc Natl Acad Sci U S A 1988
R K Moyzis, J M Buckingham, L S Cram, M Dani, L L Deaven, M D Jones, J Meyne, R L Ratliff, J R Wu. Proc Natl Acad Sci U S A 1988
13
Telomere length-dependent transcription and epigenetic modifications in promoters remote from telomere ends.
Ananda Kishore Mukherjee, Shalu Sharma, Suman Sengupta, Dhurjhoti Saha, Pankaj Kumar, Tabish Hussain, Vivek Srivastava, Sumitabho Deb Roy, Jerry W Shay, Shantanu Chowdhury. PLoS Genet 2018
Ananda Kishore Mukherjee, Shalu Sharma, Suman Sengupta, Dhurjhoti Saha, Pankaj Kumar, Tabish Hussain, Vivek Srivastava, Sumitabho Deb Roy, Jerry W Shay, Shantanu Chowdhury. PLoS Genet 2018
46
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
13
Long-Range Chromatin Interactions Drive Mutant TERT Promoter Activation.
Semih Can Akıncılar, Ekta Khattar, Priscilla Li Shan Boon, Bilal Unal, Melissa Jane Fullwood, Vinay Tergaonkar. Cancer Discov 2016
Semih Can Akıncılar, Ekta Khattar, Priscilla Li Shan Boon, Bilal Unal, Melissa Jane Fullwood, Vinay Tergaonkar. Cancer Discov 2016
12
An alternate splicing variant of the human telomerase catalytic subunit inhibits telomerase activity.
X Yi, D M White, D L Aisner, J A Baur, W E Wright, J W Shay. Neoplasia 2000
X Yi, D M White, D L Aisner, J A Baur, W E Wright, J W Shay. Neoplasia 2000
12
Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II.
Stefan Schoeftner, Maria A Blasco. Nat Cell Biol 2008
Stefan Schoeftner, Maria A Blasco. Nat Cell Biol 2008
12
Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells.
X Yi, J W Shay, W E Wright. Nucleic Acids Res 2001
X Yi, J W Shay, W E Wright. Nucleic Acids Res 2001
11
The major reverse transcriptase-incompetent splice variant of the human telomerase protein inhibits telomerase activity but protects from apoptosis.
Imke Listerman, Jie Sun, Francesca S Gazzaniga, Jason L Lukas, Elizabeth H Blackburn. Cancer Res 2013
Imke Listerman, Jie Sun, Francesca S Gazzaniga, Jason L Lukas, Elizabeth H Blackburn. Cancer Res 2013
11
Human telomeric proteins occupy selective interstitial sites.
Dong Yang, Yuanyan Xiong, Hyeung Kim, Quanyuan He, Yumei Li, Rui Chen, Zhou Songyang. Cell Res 2011
Dong Yang, Yuanyan Xiong, Hyeung Kim, Quanyuan He, Yumei Li, Rui Chen, Zhou Songyang. Cell Res 2011
11
Cancer-associated TERT promoter mutations abrogate telomerase silencing.
Kunitoshi Chiba, Joshua Z Johnson, Jacob M Vogan, Tina Wagner, John M Boyle, Dirk Hockemeyer. Elife 2015
Kunitoshi Chiba, Joshua Z Johnson, Jacob M Vogan, Tina Wagner, John M Boyle, Dirk Hockemeyer. Elife 2015
11
RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells.
Rajika Arora, Yongwoo Lee, Harry Wischnewski, Catherine M Brun, Tobias Schwarz, Claus M Azzalin. Nat Commun 2014
Rajika Arora, Yongwoo Lee, Harry Wischnewski, Catherine M Brun, Tobias Schwarz, Claus M Azzalin. Nat Commun 2014
11
Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination.
Nuno M V Gomes, Oliver A Ryder, Marlys L Houck, Suellen J Charter, William Walker, Nicholas R Forsyth, Steven N Austad, Chris Venditti, Mark Pagel, Jerry W Shay,[...]. Aging Cell 2011
Nuno M V Gomes, Oliver A Ryder, Marlys L Houck, Suellen J Charter, William Walker, Nicholas R Forsyth, Steven N Austad, Chris Venditti, Mark Pagel, Jerry W Shay,[...]. Aging Cell 2011
11
Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts.
G A Ulaner, J F Hu, T H Vu, L C Giudice, A R Hoffman. Cancer Res 1998
G A Ulaner, J F Hu, T H Vu, L C Giudice, A R Hoffman. Cancer Res 1998
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.