A citation-based method for searching scientific literature

Carlos A Matos, Luis Pereira de Almeida, Clevio Nobrega. Curr Pharm Des 2017
Times Cited: 14







List of co-cited articles
207 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease.
Ana T Simões, Nélio Gonçalves, Arnulf Koeppen, Nicole Déglon, Sebastian Kügler, Carlos Bandeira Duarte, Luís Pereira de Almeida. Brain 2012
75
64

Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3.
Annette Haacke, Sarah A Broadley, Raina Boteva, Nikolay Tzvetkov, F Ulrich Hartl, Peter Breuer. Hum Mol Genet 2006
89
50

Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3).
Jeannette Hübener, Jonasz Jeremiasz Weber, Claudia Richter, Lisa Honold, Andreas Weiss, Fabronia Murad, Peter Breuer, Ullrich Wüllner, Peter Bellstedt, Francois Paquet-Durand,[...]. Hum Mol Genet 2013
51
42

Calpain inhibition is sufficient to suppress aggregation of polyglutamine-expanded ataxin-3.
Annette Haacke, F Ulrich Hartl, Peter Breuer. J Biol Chem 2007
67
42

Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease.
Clévio Nóbrega, Sara Carmo-Silva, David Albuquerque, Ana Vasconcelos-Ferreira, Udaya-Geetha Vijayakumar, Liliana Mendonça, Hirokazu Hirai, Luís Pereira de Almeida. Brain 2015
22
35

A combinatorial approach to identify calpain cleavage sites in the Machado-Joseph disease protein ataxin-3.
Jonasz J Weber, Matthias Golla, Giambattista Guaitoli, Pimthanya Wanichawan, Stefanie N Hayer, Stefan Hauser, Ann-Christin Krahl, Maike Nagel, Sebastian Samer, Eleonora Aronica,[...]. Brain 2017
19
35

Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models.
Carlos A Matos, Clévio Nóbrega, Susana R Louros, Bruno Almeida, Elisabete Ferreiro, Jorge Valero, Luís Pereira de Almeida, Sandra Macedo-Ribeiro, Ana Luísa Carvalho. J Cell Biol 2016
22
28

Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia.
Takashi Torashima, Chiho Koyama, Akira Iizuka, Kazuhiro Mitsumura, Kiyohiko Takayama, Shigeru Yanagi, Miho Oue, Haruyasu Yamaguchi, Hirokazu Hirai. EMBO Rep 2008
82
28

Autophagy in polyglutamine disease: Imposing order on disorder or contributing to the chaos?
Constanza J Cortes, Albert R La Spada. Mol Cell Neurosci 2015
29
28

Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.
H L Paulson, M K Perez, Y Trottier, J Q Trojanowski, S H Subramony, S S Das, P Vig, J L Mandel, K H Fischbeck, R N Pittman. Neuron 1997
655
28

Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes.
Nihar Ranjan Jana, Priyanka Dikshit, Anand Goswami, Svetlana Kotliarova, Shigeo Murata, Keiji Tanaka, Nobuyuki Nukina. J Biol Chem 2005
230
28


Silencing ataxin-3 mitigates degeneration in a rat model of Machado-Joseph disease: no role for wild-type ataxin-3?
Sandro Alves, Isabel Nascimento-Ferreira, Noëlle Dufour, Raymonde Hassig, Gwennaëlle Auregan, Clévio Nóbrega, Emmanuel Brouillet, Philippe Hantraye, Maria C Pedroso de Lima, Nicole Déglon,[...]. Hum Mol Genet 2010
74
28

Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease.
Isabel Nascimento-Ferreira, Tiago Santos-Ferreira, Lígia Sousa-Ferreira, Gwennaëlle Auregan, Isabel Onofre, Sandro Alves, Noëlle Dufour, Veronica F Colomer Gould, Arnulf Koeppen, Nicole Déglon,[...]. Brain 2011
117
28

Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease.
Isabel Nascimento-Ferreira, Clévio Nóbrega, Ana Vasconcelos-Ferreira, Isabel Onofre, David Albuquerque, Célia Aveleira, Hirokazu Hirai, Nicole Déglon, Luís Pereira de Almeida. Brain 2013
66
28

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease.
Philipp Koch, Peter Breuer, Michael Peitz, Johannes Jungverdorben, Jaideep Kesavan, Daniel Poppe, Jonas Doerr, Julia Ladewig, Jerome Mertens, Thomas Tüting,[...]. Nature 2011
221
28

Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado-Joseph disease.
Ana Teresa Simões, Nélio Gonçalves, Rui Jorge Nobre, Carlos Bandeira Duarte, Luís Pereira de Almeida. Hum Mol Genet 2014
34
28

Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease.
Sandro Alves, Isabel Nascimento-Ferreira, Gwennaëlle Auregan, Raymonde Hassig, Noëlle Dufour, Emmanuel Brouillet, Maria C Pedroso de Lima, Philippe Hantraye, Luís Pereira de Almeida, Nicole Déglon. PLoS One 2008
106
28

Toward RNAi therapy for the polyglutamine disease Machado-Joseph disease.
Maria do Carmo Costa, Katiuska Luna-Cancalon, Svetlana Fischer, Naila S Ashraf, Michelle Ouyang, Rahil M Dharia, Lucas Martin-Fishman, Yemen Yang, Vikram G Shakkottai, Beverly L Davidson,[...]. Mol Ther 2013
65
28

Polyglutamine diseases: where does toxicity come from? what is toxicity? where are we going?
Toshiaki Takahashi, Shinichi Katada, Osamu Onodera. J Mol Cell Biol 2010
104
21

Polyglutamine-expanded ataxin-3 causes cerebellar dysfunction of SCA3 transgenic mice by inducing transcriptional dysregulation.
An-Hsun Chou, Tu-Hsueh Yeh, Pin Ouyang, Ying-Ling Chen, Si-Ying Chen, Hung-Li Wang. Neurobiol Dis 2008
120
21


Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3.
Xi Chen, Tie-Shan Tang, Huiping Tu, Omar Nelson, Mark Pook, Robert Hammer, Nobuyuki Nukina, Ilya Bezprozvanny. J Neurosci 2008
151
21

Non-expanded polyglutamine proteins in intranuclear inclusions of hereditary ataxias--triple-labeling immunofluorescence study.
T Uchihara, H Fujigasaki, S Koyano, A Nakamura, S Yagishita, K Iwabuchi. Acta Neuropathol 2001
63
21

Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.
Gwenn A Garden, Randell T Libby, Ying-Hui Fu, Yoshito Kinoshita, Jing Huang, Daniel E Possin, Annette C Smith, Refugio A Martinez, Gabriel C Fine, Sara K Grote,[...]. J Neurosci 2002
117
21

Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7.
Udo Rüb, Ludger Schöls, Henry Paulson, Georg Auburger, Pawel Kermer, Joanna C Jen, Kay Seidel, Horst-Werner Korf, Thomas Deller. Prog Neurobiol 2013
168
21


Phosphorylation of ataxin-3 by glycogen synthase kinase 3beta at serine 256 regulates the aggregation of ataxin-3.
Erkang Fei, Nali Jia, Tao Zhang, Xiaochuan Ma, Hongfeng Wang, Chao Liu, Wei Zhang, Lili Ding, Nobuyuki Nukina, Guanghui Wang. Biochem Biophys Res Commun 2007
40
21

Protein surveillance machinery in brains with spinocerebellar ataxia type 3: redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions.
Thorsten Schmidt, Katrin S Lindenberg, Antje Krebs, Ludger Schöls, Franco Laccone, Jochen Herms, Martin Rechsteiner, Olaf Riess, G Bernhard Landwehrmeyer. Ann Neurol 2002
104
21


Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.
C J Cummings, M A Mancini, B Antalffy, D B DeFranco, H T Orr, H Y Zoghbi. Nat Genet 1998
673
21

CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3.
Thorsten Mueller, Peter Breuer, Ina Schmitt, Jochen Walter, Bernd O Evert, Ullrich Wüllner. Hum Mol Genet 2009
65
21

A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration.
Daniel Goti, Scott M Katzen, Jesse Mez, Noam Kurtis, Jennifer Kiluk, Lea Ben-Haïem, Nancy A Jenkins, Neal G Copeland, Akira Kakizuka, Alan H Sharp,[...]. J Neurosci 2004
138
21

A mutant ataxin-3 fragment results from processing at a site N-terminal to amino acid 190 in brain of Machado-Joseph disease-like transgenic mice.
Veronica F Colomer Gould, Daniel Goti, Donna Pearce, Guillermo A Gonzalez, Hong Gao, Mario Bermudez de Leon, Nancy A Jenkins, Neal G Copeland, Christopher A Ross, Dale R Brown. Neurobiol Dis 2007
38
21

SUMO modification of Huntingtin and Huntington's disease pathology.
Joan S Steffan, Namita Agrawal, Judit Pallos, Erica Rockabrand, Lloyd C Trotman, Natalia Slepko, Katalin Illes, Tamas Lukacsovich, Ya-Zhen Zhu, Elena Cattaneo,[...]. Science 2004
476
21

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1.
Y Kawaguchi, T Okamoto, M Taniwaki, M Aizawa, M Inoue, S Katayama, H Kawakami, S Nakamura, M Nishimura, I Akiguchi. Nat Genet 1994
21

Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates.
Kathryn M Donaldson, Wei Li, Keith A Ching, Serge Batalov, Chih-Cheng Tsai, Claudio A P Joazeiro. Proc Natl Acad Sci U S A 2003
164
21

An isoform of ataxin-3 accumulates in the nucleus of neuronal cells in affected brain regions of SCA3 patients.
T Schmidt, G B Landwehrmeyer, I Schmitt, Y Trottier, G Auburger, F Laccone, T Klockgether, M Völpel, J T Epplen, L Schöls,[...]. Brain Pathol 1998
153
21

Fibroblasts of Machado Joseph Disease patients reveal autophagy impairment.
Isabel Onofre, Nuno Mendonça, Sara Lopes, Rui Nobre, Joana Barbosa de Melo, Isabel Marques Carreira, Cristina Januário, António Freire Gonçalves, Luis Pereira de Almeida. Sci Rep 2016
32
21

YAC transgenic mice carrying pathological alleles of the MJD1 locus exhibit a mild and slowly progressive cerebellar deficit.
Cemal K Cemal, Christopher J Carroll, Lorraine Lawrence, Margaret B Lowrie, Piers Ruddle, Sahar Al-Mahdawi, Rosalind H M King, Mark A Pook, Clare Huxley, Susan Chamberlain. Hum Mol Genet 2002
133
21

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Andrea Williams, Sovan Sarkar, Paul Cuddon, Evangelia K Ttofi, Shinji Saiki, Farah H Siddiqi, Luca Jahreiss, Angeleen Fleming, Dean Pask, Paul Goldsmith,[...]. Nat Chem Biol 2008
554
21

Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117.
Sokol V Todi, K Matthew Scaglione, Jessica R Blount, Venkatesha Basrur, Kevin P Conlon, Annalisa Pastore, Kojo Elenitoba-Johnson, Henry L Paulson. J Biol Chem 2010
67
21

Glutamine repeats and neurodegeneration.
H Y Zoghbi, H T Orr. Annu Rev Neurosci 2000
956
21

Ataxin-3 protein and RNA toxicity in spinocerebellar ataxia type 3: current insights and emerging therapeutic strategies.
Melvin M Evers, Lodewijk J A Toonen, Willeke M C van Roon-Mom. Mol Neurobiol 2014
46
21



SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7.
Alexandre Janer, Andreas Werner, Junko Takahashi-Fujigasaki, Aurélie Daret, Hiroto Fujigasaki, Koji Takada, Charles Duyckaerts, Alexis Brice, Anne Dejean, Annie Sittler. Hum Mol Genet 2010
66
21

Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.
Joana Duarte-Neves, Nélio Gonçalves, Janete Cunha-Santos, Ana Teresa Simões, Wilfred F A den Dunnen, Hirokazu Hirai, Sebastian Kügler, Cláudia Cavadas, Luís Pereira de Almeida. Hum Mol Genet 2015
33
21

miR-25 alleviates polyQ-mediated cytotoxicity by silencing ATXN3.
Fengzhen Huang, Li Zhang, Zhe Long, Zhao Chen, Xuan Hou, Chunrong Wang, Huirong Peng, Junling Wang, Jiada Li, Ranhui Duan,[...]. FEBS Lett 2014
27
21

Silencing mutant ATXN3 expression resolves molecular phenotypes in SCA3 transgenic mice.
Edgardo Rodríguez-Lebrón, Maria do Carmo Costa, Katiuska Luna-Cancalon, Therese M Peron, Svetlana Fischer, Ryan L Boudreau, Beverly L Davidson, Henry L Paulson. Mol Ther 2013
70
21


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.