C A Zarate, R Machado-Vieira. Mol Psychiatry 2017
Times Cited: 20
Times Cited: 20
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Antidepressant effects of ketamine in depressed patients.
R M Berman, A Cappiello, A Anand, D A Oren, G R Heninger, D S Charney, J H Krystal. Biol Psychiatry 2000
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A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression.
Carlos A Zarate, Jaskaran B Singh, Paul J Carlson, Nancy E Brutsche, Rezvan Ameli, David A Luckenbaugh, Dennis S Charney, Husseini K Manji. Arch Gen Psychiatry 2006
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mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists.
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Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.
Sungho Maeng, Carlos A Zarate, Jing Du, Robert J Schloesser, Joseph McCammon, Guang Chen, Husseini K Manji. Biol Psychiatry 2008
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Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial.
Carlos A Zarate, Nancy E Brutsche, Lobna Ibrahim, Jose Franco-Chaves, Nancy Diazgranados, Anibal Cravchik, Jessica Selter, Craig A Marquardt, Victoria Liberty, David A Luckenbaugh. Biol Psychiatry 2012
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Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics.
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Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
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KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS.
Chadi G Abdallah, Thomas G Adams, Benjamin Kelmendi, Irina Esterlis, Gerard Sanacora, John H Krystal. Depress Anxiety 2016
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R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects.
C Yang, Y Shirayama, J-c Zhang, Q Ren, W Yao, M Ma, C Dong, K Hashimoto. Transl Psychiatry 2015
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Antidepressant mechanism of ketamine: perspective from preclinical studies.
Lisa Scheuing, Chi-Tso Chiu, Hsiao-Mei Liao, De-Maw Chuang. Front Neurosci 2015
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Functional antagonists at the NMDA receptor complex exhibit antidepressant actions.
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An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder.
Sheldon H Preskorn, Bryan Baker, Sheela Kolluri, Frank S Menniti, Michael Krams, Jaren W Landen. J Clin Psychopharmacol 2008
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Randomized proof of concept trial of GLYX-13, an N-methyl-D-aspartate receptor glycine site partial agonist, in major depressive disorder nonresponsive to a previous antidepressant agent.
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Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder.
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A randomized trial of a low-trapping nonselective N-methyl-D-aspartate channel blocker in major depression.
Carlos A Zarate, Daniel Mathews, Lobna Ibrahim, Jose Franco Chaves, Craig Marquardt, Immaculata Ukoh, Libby Jolkovsky, Nancy E Brutsche, Mark A Smith, David A Luckenbaugh. Biol Psychiatry 2013
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Antidepressant Potential of (R)-Ketamine in Rodent Models: Comparison with (S)-Ketamine.
Kenichi Fukumoto, Hidetoh Toki, Michihiko Iijima, Takashi Hashihayata, Jun-Ichi Yamaguchi, Kenji Hashimoto, Shigeyuki Chaki. J Pharmacol Exp Ther 2017
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Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex.
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Single-dose infusion ketamine and non-ketamine N-methyl-d-aspartate receptor antagonists for unipolar and bipolar depression: a meta-analysis of efficacy, safety and time trajectories.
T Kishimoto, J M Chawla, K Hagi, C A Zarate, J M Kane, M Bauer, C U Correll. Psychol Med 2016
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Subanesthetic doses of ketamine stimulate psychosis in schizophrenia.
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The role of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in depression: central mediators of pathophysiology and antidepressant activity?
Florian Freudenberg, Tansu Celikel, Andreas Reif. Neurosci Biobehav Rev 2015
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(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function.
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Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action.
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Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressants.
Caroline A Browne, Irwin Lucki. Front Pharmacol 2013
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Comparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depression.
Bangkun Yang, Ji-Chun Zhang, Mei Han, Wei Yao, Chun Yang, Qian Ren, Min Ma, Qian-Xue Chen, Kenji Hashimoto. Psychopharmacology (Berl) 2016
Bangkun Yang, Ji-Chun Zhang, Mei Han, Wei Yao, Chun Yang, Qian Ren, Min Ma, Qian-Xue Chen, Kenji Hashimoto. Psychopharmacology (Berl) 2016
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PHARMACOLOGIC EFFECTS OF CI-581, A NEW DISSOCIATIVE ANESTHETIC, IN MAN.
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Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex.
Rong-Jian Liu, Francis S Lee, Xiao-Yuan Li, Francis Bambico, Ronald S Duman, George K Aghajanian. Biol Psychiatry 2012
Rong-Jian Liu, Francis S Lee, Xiao-Yuan Li, Francis Bambico, Ronald S Duman, George K Aghajanian. Biol Psychiatry 2012
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Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression.
Hiroyuki Koike, Michihiko Iijima, Shigeyuki Chaki. Behav Brain Res 2011
Hiroyuki Koike, Michihiko Iijima, Shigeyuki Chaki. Behav Brain Res 2011
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Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression.
Carlos A Zarate, Nancy Brutsche, Gonzalo Laje, David A Luckenbaugh, Swarajya L Vattem Venkata, Anuradha Ramamoorthy, Ruin Moaddel, Irving W Wainer. Biol Psychiatry 2012
Carlos A Zarate, Nancy Brutsche, Gonzalo Laje, David A Luckenbaugh, Swarajya L Vattem Venkata, Anuradha Ramamoorthy, Ruin Moaddel, Irving W Wainer. Biol Psychiatry 2012
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A Randomized, placebo-controlled, crossover pilot trial of the oral selective NR2B antagonist MK-0657 in patients with treatment-resistant major depressive disorder.
Lobna Ibrahim, Nancy Diaz Granados, Libby Jolkovsky, Nancy Brutsche, David A Luckenbaugh, W Joseph Herring, William Z Potter, Carlos A Zarate. J Clin Psychopharmacol 2012
Lobna Ibrahim, Nancy Diaz Granados, Libby Jolkovsky, Nancy Brutsche, David A Luckenbaugh, W Joseph Herring, William Z Potter, Carlos A Zarate. J Clin Psychopharmacol 2012
15
Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression.
Xiaochen Zhao, Swarajya Lakshmi Vattem Venkata, Ruin Moaddel, Dave A Luckenbaugh, Nancy E Brutsche, Lobna Ibrahim, Carlos A Zarate, Donald E Mager, Irving W Wainer. Br J Clin Pharmacol 2012
Xiaochen Zhao, Swarajya Lakshmi Vattem Venkata, Ruin Moaddel, Dave A Luckenbaugh, Nancy E Brutsche, Lobna Ibrahim, Carlos A Zarate, Donald E Mager, Irving W Wainer. Br J Clin Pharmacol 2012
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Ketamine as the prototype glutamatergic antidepressant: pharmacodynamic actions, and a systematic review and meta-analysis of efficacy.
Caroline Caddy, Giovanni Giaroli, Thomas P White, Sukhwinder S Shergill, Derek K Tracy. Ther Adv Psychopharmacol 2014
Caroline Caddy, Giovanni Giaroli, Thomas P White, Sukhwinder S Shergill, Derek K Tracy. Ther Adv Psychopharmacol 2014
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Investigational drugs in recent clinical trials for treatment-resistant depression.
Ricardo P Garay, Carlos A Zarate, Thomas Charpeaud, Leslie Citrome, Christoph U Correll, Ahcène Hameg, Pierre-Michel Llorca. Expert Rev Neurother 2017
Ricardo P Garay, Carlos A Zarate, Thomas Charpeaud, Leslie Citrome, Christoph U Correll, Ahcène Hameg, Pierre-Michel Llorca. Expert Rev Neurother 2017
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Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression.
D Jeffrey Newport, Linda L Carpenter, William M McDonald, James B Potash, Mauricio Tohen, Charles B Nemeroff. Am J Psychiatry 2015
D Jeffrey Newport, Linda L Carpenter, William M McDonald, James B Potash, Mauricio Tohen, Charles B Nemeroff. Am J Psychiatry 2015
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Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation.
M M Harraz, R Tyagi, P Cortés, S H Snyder. Mol Psychiatry 2016
M M Harraz, R Tyagi, P Cortés, S H Snyder. Mol Psychiatry 2016
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Antidepressant actions of ketamine: from molecular mechanisms to clinical practice.
Lisa M Monteggia, Carlos Zarate. Curr Opin Neurobiol 2015
Lisa M Monteggia, Carlos Zarate. Curr Opin Neurobiol 2015
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Adjunctive Lanicemine (AZD6765) in Patients with Major Depressive Disorder and History of Inadequate Response to Antidepressants: A Randomized, Placebo-Controlled Study.
Gerard Sanacora, Michael R Johnson, Arif Khan, Sarah D Atkinson, Robert R Riesenberg, Juan P Schronen, Michael A Burke, John M Zajecka, Luis Barra, Hong-Lin Su,[...]. Neuropsychopharmacology 2017
Gerard Sanacora, Michael R Johnson, Arif Khan, Sarah D Atkinson, Robert R Riesenberg, Juan P Schronen, Michael A Burke, John M Zajecka, Luis Barra, Hong-Lin Su,[...]. Neuropsychopharmacology 2017
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Convergent Mechanisms Underlying Rapid Antidepressant Action.
Panos Zanos, Scott M Thompson, Ronald S Duman, Carlos A Zarate, Todd D Gould. CNS Drugs 2018
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Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression: A Randomized Clinical Trial.
Ella J Daly, Madhukar H Trivedi, Adam Janik, Honglan Li, Yun Zhang, Xiang Li, Rosanne Lane, Pilar Lim, Anna R Duca, David Hough,[...]. JAMA Psychiatry 2019
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Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial.
James W Murrough, Dan V Iosifescu, Lee C Chang, Rayan K Al Jurdi, Charles E Green, Andrew M Perez, Syed Iqbal, Sarah Pillemer, Alexandra Foulkes, Asim Shah,[...]. Am J Psychiatry 2013
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Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation.
R N Moda-Sava, M H Murdock, P K Parekh, R N Fetcho, B S Huang, T N Huynh, J Witztum, D C Shaver, D L Rosenthal, E J Alway,[...]. Science 2019
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Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study.
Carla M Canuso, Jaskaran B Singh, Maggie Fedgchin, Larry Alphs, Rosanne Lane, Pilar Lim, Christine Pinter, David Hough, Gerard Sanacora, Husseini Manji,[...]. Am J Psychiatry 2018
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The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis.
Samuel T Wilkinson, Elizabeth D Ballard, Michael H Bloch, Sanjay J Mathew, James W Murrough, Adriana Feder, Peter Sos, Gang Wang, Carlos A Zarate, Gerard Sanacora. Am J Psychiatry 2018
Samuel T Wilkinson, Elizabeth D Ballard, Michael H Bloch, Sanjay J Mathew, James W Murrough, Adriana Feder, Peter Sos, Gang Wang, Carlos A Zarate, Gerard Sanacora. Am J Psychiatry 2018
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Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression.
James W Murrough, Andrew M Perez, Sarah Pillemer, Jessica Stern, Michael K Parides, Marije aan het Rot, Katherine A Collins, Sanjay J Mathew, Dennis S Charney, Dan V Iosifescu. Biol Psychiatry 2013
James W Murrough, Andrew M Perez, Sarah Pillemer, Jessica Stern, Michael K Parides, Marije aan het Rot, Katherine A Collins, Sanjay J Mathew, Dennis S Charney, Dan V Iosifescu. Biol Psychiatry 2013
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Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial.
Stephen Kanes, Helen Colquhoun, Handan Gunduz-Bruce, Shane Raines, Ryan Arnold, Amy Schacterle, James Doherty, C Neill Epperson, Kristina M Deligiannidis, Robert Riesenberg,[...]. Lancet 2017
Stephen Kanes, Helen Colquhoun, Handan Gunduz-Bruce, Shane Raines, Ryan Arnold, Amy Schacterle, James Doherty, C Neill Epperson, Kristina M Deligiannidis, Robert Riesenberg,[...]. Lancet 2017
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Efficacy and Safety of Intranasal Esketamine Adjunctive to Oral Antidepressant Therapy in Treatment-Resistant Depression: A Randomized Clinical Trial.
Ella J Daly, Jaskaran B Singh, Maggie Fedgchin, Kimberly Cooper, Pilar Lim, Richard C Shelton, Michael E Thase, Andrew Winokur, Luc Van Nueten, Husseini Manji,[...]. JAMA Psychiatry 2018
Ella J Daly, Jaskaran B Singh, Maggie Fedgchin, Kimberly Cooper, Pilar Lim, Richard C Shelton, Michael E Thase, Andrew Winokur, Luc Van Nueten, Husseini Manji,[...]. JAMA Psychiatry 2018
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A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression.
Nancy Diazgranados, Lobna Ibrahim, Nancy E Brutsche, Andrew Newberg, Phillip Kronstein, Sami Khalife, William A Kammerer, Zenaide Quezado, David A Luckenbaugh, Giacomo Salvadore,[...]. Arch Gen Psychiatry 2010
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Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Adriana Feder, Michael K Parides, James W Murrough, Andrew M Perez, Julia E Morgan, Shireen Saxena, Katherine Kirkwood, Marije Aan Het Rot, Kyle A B Lapidus, Le-Ben Wan,[...]. JAMA Psychiatry 2014
Adriana Feder, Michael K Parides, James W Murrough, Andrew M Perez, Julia E Morgan, Shireen Saxena, Katherine Kirkwood, Marije Aan Het Rot, Kyle A B Lapidus, Le-Ben Wan,[...]. JAMA Psychiatry 2014
15
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.