Chia-Hsueh Lee, Roderick MacKinnon. Cell 2017
Times Cited: 186
Times Cited: 186
Times Cited
Times Co-cited
Similarity
Structure of the voltage-gated K⁺ channel Eag1 reveals an alternative voltage sensing mechanism.
Jonathan R Whicher, Roderick MacKinnon. Science 2016
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Helix breaking transition in the S4 of HCN channel is critical for hyperpolarization-dependent gating.
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Stephen B Long, Ernest B Campbell, Roderick Mackinnon. Science 2005
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Stephen B Long, Ernest B Campbell, Roderick Mackinnon. Science 2005
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A family of hyperpolarization-activated mammalian cation channels.
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The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels.
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Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
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Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.
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Structural insights into the mechanisms of CNBD channel function.
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CryoEM structure of a prokaryotic cyclic nucleotide-gated ion channel.
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Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains.
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Bipolar switching by HCN voltage sensor underlies hyperpolarization activation.
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The HCN channel voltage sensor undergoes a large downward motion during hyperpolarization.
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Molecular identification of a hyperpolarization-activated channel in sea urchin sperm.
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Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment.
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Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.
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Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels.
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Blocker state dependence and trapping in hyperpolarization-activated cation channels: evidence for an intracellular activation gate.
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UCSF Chimera--a visualization system for exploratory research and analysis.
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Cryo-EM structure of the open high-conductance Ca2+-activated K+ channel.
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Two pacemaker channels from human heart with profoundly different activation kinetics.
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HCN2 ion channels play a central role in inflammatory and neuropathic pain.
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Voltage-dependent gating of hyperpolarization-activated, cyclic nucleotide-gated pacemaker channels: molecular coupling between the S4-S5 and C-linkers.
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The crystal structure of a voltage-gated sodium channel.
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Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome.
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A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP.
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Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide-gated cation channel.
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Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1.
Michael David Clark, Gustavo F Contreras, Rong Shen, Eduardo Perozo. Nature 2020
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Contribution of the S4 segment to gating charge in the Shaker K+ channel.
S K Aggarwal, R MacKinnon. Neuron 1996
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S4 movement in a mammalian HCN channel.
Sriharsha Vemana, Shilpi Pandey, H Peter Larsson. J Gen Physiol 2004
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Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Jan Rheinberger, Xiaolong Gao, Philipp Am Schmidpeter, Crina M Nimigean. Elife 2018
Jan Rheinberger, Xiaolong Gao, Philipp Am Schmidpeter, Crina M Nimigean. Elife 2018
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.