A citation-based method for searching scientific literature

Adewale Adegbuyiro, Faezeh Sedighi, Albert W Pilkington, Sharon Groover, Justin Legleiter. Biochemistry 2017
Times Cited: 59







List of co-cited articles
566 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism.
Ashwani K Thakur, Murali Jayaraman, Rakesh Mishra, Monika Thakur, Veronique M Chellgren, In-Ja L Byeon, Dalaver H Anjum, Ravindra Kodali, Trevor P Creamer, James F Conway,[...]. Nat Struct Mol Biol 2009
296
27


Oligoproline effects on polyglutamine conformation and aggregation.
Anusri Bhattacharyya, Ashwani K Thakur, Veronique M Chellgren, Geetha Thiagarajan, Angela D Williams, Brian W Chellgren, Trevor P Creamer, Ronald Wetzel. J Mol Biol 2006
183
20

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
18

Trinucleotide repeat disorders.
Harry T Orr, Huda Y Zoghbi. Annu Rev Neurosci 2007
951
15


Flanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure.
Gregory Darnell, Joseph P R O Orgel, Reinhard Pahl, Stephen C Meredith. J Mol Biol 2007
113
13


Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, R Hasenbank, G P Bates, S W Davies, H Lehrach, E E Wanker. Cell 1997
978
13

SUMO modification of Huntingtin and Huntington's disease pathology.
Joan S Steffan, Namita Agrawal, Judit Pallos, Erica Rockabrand, Lloyd C Trotman, Natalia Slepko, Katalin Illes, Tamas Lukacsovich, Ya-Zhen Zhu, Elena Cattaneo,[...]. Science 2004
472
13

The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
311
13

Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation.
Scott L Crick, Kiersten M Ruff, Kanchan Garai, Carl Frieden, Rohit V Pappu. Proc Natl Acad Sci U S A 2013
119
13

The interaction of polyglutamine peptides with lipid membranes is regulated by flanking sequences associated with huntingtin.
Kathleen A Burke, Karlina J Kauffman, C Samuel Umbaugh, Shelli L Frey, Justin Legleiter. J Biol Chem 2013
52
15

Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.
Xiaofeng Gu, Erin R Greiner, Rakesh Mishra, Ravindra Kodali, Alex Osmand, Steven Finkbeiner, Joan S Steffan, Leslie Michels Thompson, Ronald Wetzel, X William Yang. Neuron 2009
208
11

Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization.
Michelle A Poirier, Huilin Li, Jed Macosko, Shuowei Cai, Mario Amzel, Christopher A Ross. J Biol Chem 2002
273
11

Critical nucleus size for disease-related polyglutamine aggregation is repeat-length dependent.
Karunakar Kar, Murali Jayaraman, Bankanidhi Sahoo, Ravindra Kodali, Ronald Wetzel. Nat Struct Mol Biol 2011
141
11

Mutant huntingtin fragments form oligomers in a polyglutamine length-dependent manner in vitro and in vivo.
Justin Legleiter, Emily Mitchell, Gregor P Lotz, Ellen Sapp, Cheping Ng, Marian DiFiglia, Leslie M Thompson, Paul J Muchowski. J Biol Chem 2010
137
11

A toxic monomeric conformer of the polyglutamine protein.
Yoshitaka Nagai, Takashi Inui, H Akiko Popiel, Nobuhiro Fujikake, Kazuhiro Hasegawa, Yoshihiro Urade, Yuji Goto, Hironobu Naiki, Tatsushi Toda. Nat Struct Mol Biol 2007
230
11

Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation.
Songming Chen, Frank A Ferrone, Ronald Wetzel. Proc Natl Acad Sci U S A 2002
385
11

Inhibiting the nucleation of amyloid structure in a huntingtin fragment by targeting α-helix-rich oligomeric intermediates.
Rakesh Mishra, Murali Jayaraman, Bartholomew P Roland, Elizabeth Landrum, Timothy Fullam, Ravindra Kodali, Ashwani K Thakur, Irene Arduini, Ronald Wetzel. J Mol Biol 2012
60
11

Slow amyloid nucleation via α-helix-rich oligomeric intermediates in short polyglutamine-containing huntingtin fragments.
Murali Jayaraman, Ravindra Kodali, Bankanidhi Sahoo, Ashwani K Thakur, Anand Mayasundari, Rakesh Mishra, Cynthia B Peterson, Ronald Wetzel. J Mol Biol 2012
121
11

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
11

In Situ Architecture and Cellular Interactions of PolyQ Inclusions.
Felix J B Bäuerlein, Itika Saha, Archana Mishra, Maria Kalemanov, Antonio Martínez-Sánchez, Rüdiger Klein, Irina Dudanova, Mark S Hipp, F Ulrich Hartl, Wolfgang Baumeister,[...]. Cell 2017
115
11

The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation.
Stephen Tam, Christoph Spiess, William Auyeung, Lukasz Joachimiak, Bryan Chen, Michelle A Poirier, Judith Frydman. Nat Struct Mol Biol 2009
169
10

Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity.
Charity T Aiken, Joan S Steffan, Cortnie M Guerrero, Hasan Khashwji, Tamas Lukacsovich, Danielle Simmons, Judy M Purcell, Kimia Menhaji, Ya-Zhen Zhu, Kim Green,[...]. J Biol Chem 2009
105
10

Acetylation within the First 17 Residues of Huntingtin Exon 1 Alters Aggregation and Lipid Binding.
Maxmore Chaibva, Sudi Jawahery, Albert W Pilkington, James R Arndt, Olivia Sarver, Stephen Valentine, Silvina Matysiak, Justin Legleiter. Biophys J 2016
30
20

Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks.
Martin H Schaefer, Erich E Wanker, Miguel A Andrade-Navarro. Nucleic Acids Res 2012
111
10

Protein aggregation and neurodegenerative disease.
Christopher A Ross, Michelle A Poirier. Nat Med 2004
10

Sequence Context Influences the Structure and Aggregation Behavior of a PolyQ Tract.
Bahareh Eftekharzadeh, Alessandro Piai, Giulio Chiesa, Daniele Mungianu, Jesús García, Roberta Pierattelli, Isabella C Felli, Xavier Salvatella. Biophys J 2016
34
17

Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract.
Koning Shen, Barbara Calamini, Jonathan A Fauerbach, Boxue Ma, Sarah H Shahmoradian, Ivana L Serrano Lachapel, Wah Chiu, Donald C Lo, Judith Frydman. Elife 2016
29
20

Glutamine repeats and neurodegeneration.
H Y Zoghbi, H T Orr. Annu Rev Neurosci 2000
950
10

Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin.
Nicholas Stephane Caron, Carly Robyn Desmond, Jianrun Xia, Ray Truant. Proc Natl Acad Sci U S A 2013
82
10

Molecular interaction between the chaperone Hsc70 and the N-terminal flank of huntingtin exon 1 modulates aggregation.
Elodie Monsellier, Virginie Redeker, Gemma Ruiz-Arlandis, Luc Bousset, Ronald Melki. J Biol Chem 2015
49
12

Fibril polymorphism affects immobilized non-amyloid flanking domains of huntingtin exon1 rather than its polyglutamine core.
Hsiang-Kai Lin, Jennifer C Boatz, Inge E Krabbendam, Ravindra Kodali, Zhipeng Hou, Ronald Wetzel, Amalia M Dolga, Michelle A Poirier, Patrick C A van der Wel. Nat Commun 2017
40
15

Secondary structure of Huntingtin amino-terminal region.
Mee Whi Kim, Yogarany Chelliah, Sang Woo Kim, Zbyszek Otwinowski, Ilya Bezprozvanny. Structure 2009
177
10

The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis.
Erica Rockabrand, Natalia Slepko, Antonello Pantalone, Vidya N Nukala, Aleksey Kazantsev, J Lawrence Marsh, Patrick G Sullivan, Joan S Steffan, Stefano L Sensi, Leslie Michels Thompson. Hum Mol Genet 2007
184
10

The aggregation-enhancing huntingtin N-terminus is helical in amyloid fibrils.
V N Sivanandam, Murali Jayaraman, Cody L Hoop, Ravindra Kodali, Ronald Wetzel, Patrick C A van der Wel. J Am Chem Soc 2011
109
10

Curvature enhances binding and aggregation of huntingtin at lipid membranes.
Maxmore Chaibva, Kathleen A Burke, Justin Legleiter. Biochemistry 2014
29
20

The 17-residue-long N terminus in huntingtin controls stepwise aggregation in solution and on membranes via different mechanisms.
Nitin K Pandey, J Mario Isas, Anoop Rawat, Rachel V Lee, Jennifer Langen, Priyatama Pandey, Ralf Langen. J Biol Chem 2018
23
26

The emerging role of the first 17 amino acids of huntingtin in Huntington's disease.
James R Arndt, Maxmore Chaibva, Justin Legleiter. Biomol Concepts 2015
28
21

Kinetically competing huntingtin aggregation pathways control amyloid polymorphism and properties.
Murali Jayaraman, Rakesh Mishra, Ravindra Kodali, Ashwani K Thakur, Leonardus M I Koharudin, Angela M Gronenborn, Ronald Wetzel. Biochemistry 2012
46
13

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity.
Randy Singh Atwal, Jianrun Xia, Deborah Pinchev, Jillian Taylor, Richard M Epand, Ray Truant. Hum Mol Genet 2007
248
10


Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
489
10

Assessing mutant huntingtin fragment and polyglutamine aggregation by atomic force microscopy.
Kathleen A Burke, Jordan Godbey, Justin Legleiter. Methods 2011
39
15

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
238
8

Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core.
Cody L Hoop, Hsiang-Kai Lin, Karunakar Kar, Gábor Magyarfalvi, Jonathan M Lamley, Jennifer C Boatz, Abhishek Mandal, Józef R Lewandowski, Ronald Wetzel, Patrick C A van der Wel. Proc Natl Acad Sci U S A 2016
82
8

Polyglutamine tracts regulate beclin 1-dependent autophagy.
Avraham Ashkenazi, Carla F Bento, Thomas Ricketts, Mariella Vicinanza, Farah Siddiqi, Mariana Pavel, Ferdinando Squitieri, Maarten C Hardenberg, Sara Imarisio, Fiona M Menzies,[...]. Nature 2017
159
8


Structure and Dynamics of the Huntingtin Exon-1 N-Terminus: A Solution NMR Perspective.
Maria Baias, Pieter E S Smith, Koning Shen, Lukasz A Joachimiak, Szymon Żerko, Wiktor Koźmiński, Judith Frydman, Lucio Frydman. J Am Chem Soc 2017
35
14


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.