Patrycja Puchalska, Peter A Crawford. Cell Metab 2017
Times Cited: 509
Times Cited: 509
Times Cited
Times Co-cited
Similarity
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor.
Tadahiro Shimazu, Matthew D Hirschey, John Newman, Wenjuan He, Kotaro Shirakawa, Natacha Le Moan, Carrie A Grueter, Hyungwook Lim, Laura R Saunders, Robert D Stevens,[...]. Science 2013
Tadahiro Shimazu, Matthew D Hirschey, John Newman, Wenjuan He, Kotaro Shirakawa, Natacha Le Moan, Carrie A Grueter, Hyungwook Lim, Laura R Saunders, Robert D Stevens,[...]. Science 2013
24
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Yun-Hee Youm, Kim Y Nguyen, Ryan W Grant, Emily L Goldberg, Monica Bodogai, Dongin Kim, Dominic D'Agostino, Noah Planavsky, Christopher Lupfer, Thirumala D Kanneganti,[...]. Nat Med 2015
Yun-Hee Youm, Kim Y Nguyen, Ryan W Grant, Emily L Goldberg, Monica Bodogai, Dongin Kim, Dominic D'Agostino, Noah Planavsky, Christopher Lupfer, Thirumala D Kanneganti,[...]. Nat Med 2015
17
16
The Failing Heart Relies on Ketone Bodies as a Fuel.
Gregory Aubert, Ola J Martin, Julie L Horton, Ling Lai, Rick B Vega, Teresa C Leone, Timothy Koves, Stephen J Gardell, Marcus Krüger, Charles L Hoppel,[...]. Circulation 2016
Gregory Aubert, Ola J Martin, Julie L Horton, Ling Lai, Rick B Vega, Teresa C Leone, Timothy Koves, Stephen J Gardell, Marcus Krüger, Charles L Hoppel,[...]. Circulation 2016
16
Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure.
Kenneth C Bedi, Nathaniel W Snyder, Jeffrey Brandimarto, Moez Aziz, Clementina Mesaros, Andrew J Worth, Linda L Wang, Ali Javaheri, Ian A Blair, Kenneth B Margulies,[...]. Circulation 2016
Kenneth C Bedi, Nathaniel W Snyder, Jeffrey Brandimarto, Moez Aziz, Clementina Mesaros, Andrew J Worth, Linda L Wang, Ali Javaheri, Ian A Blair, Kenneth B Margulies,[...]. Circulation 2016
16
Cardiovascular Effects of Treatment With the Ketone Body 3-Hydroxybutyrate in Chronic Heart Failure Patients.
Roni Nielsen, Niels Møller, Lars C Gormsen, Lars Poulsen Tolbod, Nils Henrik Hansson, Jens Sorensen, Hendrik Johannes Harms, Jørgen Frøkiær, Hans Eiskjaer, Nichlas Riise Jespersen,[...]. Circulation 2019
Roni Nielsen, Niels Møller, Lars C Gormsen, Lars Poulsen Tolbod, Nils Henrik Hansson, Jens Sorensen, Hendrik Johannes Harms, Jørgen Frøkiær, Hans Eiskjaer, Nichlas Riise Jespersen,[...]. Circulation 2019
12
Ketone body metabolism and cardiovascular disease.
David G Cotter, Rebecca C Schugar, Peter A Crawford. Am J Physiol Heart Circ Physiol 2013
David G Cotter, Rebecca C Schugar, Peter A Crawford. Am J Physiol Heart Circ Physiol 2013
11
The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense.
Julie L Horton, Michael T Davidson, Clara Kurishima, Rick B Vega, Jeffery C Powers, Timothy R Matsuura, Christopher Petucci, E Douglas Lewandowski, Peter A Crawford, Deborah M Muoio,[...]. JCI Insight 2019
Julie L Horton, Michael T Davidson, Clara Kurishima, Rick B Vega, Jeffery C Powers, Timothy R Matsuura, Christopher Petucci, E Douglas Lewandowski, Peter A Crawford, Deborah M Muoio,[...]. JCI Insight 2019
10
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.
Bernard Zinman, Christoph Wanner, John M Lachin, David Fitchett, Erich Bluhmki, Stefan Hantel, Michaela Mattheus, Theresa Devins, Odd Erik Johansen, Hans J Woerle,[...]. N Engl J Med 2015
Bernard Zinman, Christoph Wanner, John M Lachin, David Fitchett, Erich Bluhmki, Stefan Hantel, Michaela Mattheus, Theresa Devins, Odd Erik Johansen, Hans J Woerle,[...]. N Engl J Med 2015
10
Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency.
Kim L Ho, Liyan Zhang, Cory Wagg, Rami Al Batran, Keshav Gopal, Jody Levasseur, Teresa Leone, Jason R B Dyck, John R Ussher, Deborah M Muoio,[...]. Cardiovasc Res 2019
Kim L Ho, Liyan Zhang, Cory Wagg, Rami Al Batran, Keshav Gopal, Jody Levasseur, Teresa Leone, Jason R B Dyck, John R Ussher, Deborah M Muoio,[...]. Cardiovasc Res 2019
13
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes.
Ele Ferrannini, Simona Baldi, Silvia Frascerra, Brenno Astiarraga, Tim Heise, Roberto Bizzotto, Andrea Mari, Thomas R Pieber, Elza Muscelli. Diabetes 2016
Ele Ferrannini, Simona Baldi, Silvia Frascerra, Brenno Astiarraga, Tim Heise, Roberto Bizzotto, Andrea Mari, Thomas R Pieber, Elza Muscelli. Diabetes 2016
9
Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes.
Pete J Cox, Tom Kirk, Tom Ashmore, Kristof Willerton, Rhys Evans, Alan Smith, Andrew J Murray, Brianna Stubbs, James West, Stewart W McLure,[...]. Cell Metab 2016
Pete J Cox, Tom Kirk, Tom Ashmore, Kristof Willerton, Rhys Evans, Alan Smith, Andrew J Murray, Brianna Stubbs, James West, Stewart W McLure,[...]. Cell Metab 2016
8
Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet.
Chia-Wei Cheng, Moshe Biton, Adam L Haber, Nuray Gunduz, George Eng, Liam T Gaynor, Surya Tripathi, Gizem Calibasi-Kocal, Steffen Rickelt, Vincent L Butty,[...]. Cell 2019
Chia-Wei Cheng, Moshe Biton, Adam L Haber, Nuray Gunduz, George Eng, Liam T Gaynor, Surya Tripathi, Gizem Calibasi-Kocal, Steffen Rickelt, Vincent L Butty,[...]. Cell 2019
8
Cardiac-Specific Bdh1 Overexpression Ameliorates Oxidative Stress and Cardiac Remodeling in Pressure Overload-Induced Heart Failure.
Motoki Uchihashi, Atsushi Hoshino, Yoshifumi Okawa, Makoto Ariyoshi, Satoshi Kaimoto, Shuhei Tateishi, Kazunori Ono, Ryoetsu Yamanaka, Daichi Hato, Yohei Fushimura,[...]. Circ Heart Fail 2017
Motoki Uchihashi, Atsushi Hoshino, Yoshifumi Okawa, Makoto Ariyoshi, Satoshi Kaimoto, Shuhei Tateishi, Kazunori Ono, Ryoetsu Yamanaka, Daichi Hato, Yohei Fushimura,[...]. Circ Heart Fail 2017
12
CV Protection in the EMPA-REG OUTCOME Trial: A "Thrifty Substrate" Hypothesis.
Ele Ferrannini, Michael Mark, Eric Mayoux. Diabetes Care 2016
Ele Ferrannini, Michael Mark, Eric Mayoux. Diabetes Care 2016
7
Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment.
Anna E Wentz, D André d'Avignon, Mary L Weber, David G Cotter, Jason M Doherty, Robnet Kerns, Rakesh Nagarajan, Naveen Reddy, Nandakumar Sambandam, Peter A Crawford. J Biol Chem 2010
Anna E Wentz, D André d'Avignon, Mary L Weber, David G Cotter, Jason M Doherty, Robnet Kerns, Rakesh Nagarajan, Naveen Reddy, Nandakumar Sambandam, Peter A Crawford. J Biol Chem 2010
8
Insulin, ketone bodies, and mitochondrial energy transduction.
K Sato, Y Kashiwaya, C A Keon, N Tsuchiya, M T King, G K Radda, B Chance, K Clarke, R L Veech. FASEB J 1995
K Sato, Y Kashiwaya, C A Keon, N Tsuchiya, M T King, G K Radda, B Chance, K Clarke, R L Veech. FASEB J 1995
7
Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling.
Rebecca C Schugar, Ashley R Moll, D André d'Avignon, Carla J Weinheimer, Attila Kovacs, Peter A Crawford. Mol Metab 2014
Rebecca C Schugar, Ashley R Moll, D André d'Avignon, Carla J Weinheimer, Attila Kovacs, Peter A Crawford. Mol Metab 2014
7
Implications of Altered Ketone Metabolism and Therapeutic Ketosis in Heart Failure.
Senthil Selvaraj, Daniel P Kelly, Kenneth B Margulies. Circulation 2020
Senthil Selvaraj, Daniel P Kelly, Kenneth B Margulies. Circulation 2020
15
SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition.
Issei Tomita, Shinji Kume, Sho Sugahara, Norihisa Osawa, Kosuke Yamahara, Mako Yasuda-Yamahara, Naoko Takeda, Masami Chin-Kanasaki, Tatsuroh Kaneko, Eric Mayoux,[...]. Cell Metab 2020
Issei Tomita, Shinji Kume, Sho Sugahara, Norihisa Osawa, Kosuke Yamahara, Mako Yasuda-Yamahara, Naoko Takeda, Masami Chin-Kanasaki, Tatsuroh Kaneko, Eric Mayoux,[...]. Cell Metab 2020
9
Ketone body production and disposal: effects of fasting, diabetes, and exercise.
E O Balasse, F Féry. Diabetes Metab Rev 1989
E O Balasse, F Féry. Diabetes Metab Rev 1989
7
Physiological roles of ketone bodies as substrates and signals in mammalian tissues.
A M Robinson, D H Williamson. Physiol Rev 1980
A M Robinson, D H Williamson. Physiol Rev 1980
7
Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia.
David G Cotter, Baris Ercal, Xiaojing Huang, Jamison M Leid, D André d'Avignon, Mark J Graham, Dennis J Dietzen, Elizabeth M Brunt, Gary J Patti, Peter A Crawford. J Clin Invest 2014
David G Cotter, Baris Ercal, Xiaojing Huang, Jamison M Leid, D André d'Avignon, Mark J Graham, Dennis J Dietzen, Elizabeth M Brunt, Gary J Patti, Peter A Crawford. J Clin Invest 2014
7
Myocardial fatty acid metabolism in health and disease.
Gary D Lopaschuk, John R Ussher, Clifford D L Folmes, Jagdip S Jaswal, William C Stanley. Physiol Rev 2010
Gary D Lopaschuk, John R Ussher, Clifford D L Folmes, Jagdip S Jaswal, William C Stanley. Physiol Rev 2010
6
The retinal pigment epithelium utilizes fatty acids for ketogenesis.
Jeffrey Adijanto, Jianhai Du, Cynthia Moffat, Erin L Seifert, James B Hurle, Nancy J Philp. J Biol Chem 2014
Jeffrey Adijanto, Jianhai Du, Cynthia Moffat, Erin L Seifert, James B Hurle, Nancy J Philp. J Biol Chem 2014
7
Can a Shift in Fuel Energetics Explain the Beneficial Cardiorenal Outcomes in the EMPA-REG OUTCOME Study? A Unifying Hypothesis.
Sunder Mudaliar, Sindura Alloju, Robert R Henry. Diabetes Care 2016
Sunder Mudaliar, Sindura Alloju, Robert R Henry. Diabetes Care 2016
6
Ketone bodies: a review of physiology, pathophysiology and application of monitoring to diabetes.
L Laffel. Diabetes Metab Res Rev 1999
L Laffel. Diabetes Metab Res Rev 1999
6
The diabetic heart utilizes ketone bodies as an energy source.
Yuji Mizuno, Eisaku Harada, Hitoshi Nakagawa, Yoshinobu Morikawa, Makoto Shono, Fumihito Kugimiya, Michihiro Yoshimura, Hirofumi Yasue. Metabolism 2017
Yuji Mizuno, Eisaku Harada, Hitoshi Nakagawa, Yoshinobu Morikawa, Makoto Shono, Fumihito Kugimiya, Michihiro Yoshimura, Hirofumi Yasue. Metabolism 2017
8
Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells.
Qi Yan Ang, Margaret Alexander, John C Newman, Yuan Tian, Jingwei Cai, Vaibhav Upadhyay, Jessie A Turnbaugh, Eric Verdin, Kevin D Hall, Rudolph L Leibel,[...]. Cell 2020
Qi Yan Ang, Margaret Alexander, John C Newman, Yuan Tian, Jingwei Cai, Vaibhav Upadhyay, Jessie A Turnbaugh, Eric Verdin, Kevin D Hall, Rudolph L Leibel,[...]. Cell 2020
6
Blood ketone bodies in congestive heart failure.
J Lommi, M Kupari, P Koskinen, H Näveri, H Leinonen, K Pulkki, M Härkönen. J Am Coll Cardiol 1996
J Lommi, M Kupari, P Koskinen, H Näveri, H Leinonen, K Pulkki, M Härkönen. J Am Coll Cardiol 1996
6
Comprehensive quantification of fuel use by the failing and nonfailing human heart.
Danielle Murashige, Cholsoon Jang, Michael Neinast, Jonathan J Edwards, Alexis Cowan, Matthew C Hyman, Joshua D Rabinowitz, David S Frankel, Zolt Arany. Science 2020
Danielle Murashige, Cholsoon Jang, Michael Neinast, Jonathan J Edwards, Alexis Cowan, Matthew C Hyman, Joshua D Rabinowitz, David S Frankel, Zolt Arany. Science 2020
7
SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease.
So Ra Kim, Sang-Guk Lee, Soo Hyun Kim, Jin Hee Kim, Eunhye Choi, Wonhee Cho, John Hoon Rim, Inhwa Hwang, Chan Joo Lee, Minyoung Lee,[...]. Nat Commun 2020
So Ra Kim, Sang-Guk Lee, Soo Hyun Kim, Jin Hee Kim, Eunhye Choi, Wonhee Cho, John Hoon Rim, Inhwa Hwang, Chan Joo Lee, Minyoung Lee,[...]. Nat Commun 2020
6
Targeting Mitochondria-Inflammation Circuit by β-Hydroxybutyrate Mitigates HFpEF.
Yan Deng, Maodi Xie, Qian Li, Xuewen Xu, Wei Ou, Yabing Zhang, Haitao Xiao, Hai Yu, Yanyi Zheng, Yu Liang,[...]. Circ Res 2021
Yan Deng, Maodi Xie, Qian Li, Xuewen Xu, Wei Ou, Yabing Zhang, Haitao Xiao, Hai Yu, Yanyi Zheng, Yu Liang,[...]. Circ Res 2021
10
SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production.
Tadahiro Shimazu, Matthew D Hirschey, Lan Hua, Kristin E Dittenhafer-Reed, Bjoern Schwer, David B Lombard, Yu Li, Jakob Bunkenborg, Frederick W Alt, John M Denu,[...]. Cell Metab 2010
Tadahiro Shimazu, Matthew D Hirschey, Lan Hua, Kristin E Dittenhafer-Reed, Bjoern Schwer, David B Lombard, Yu Li, Jakob Bunkenborg, Frederick W Alt, John M Denu,[...]. Cell Metab 2010
6
Beneficial effects of the ketogenic diet on nonalcoholic fatty liver disease: A comprehensive review of the literature.
Mikiko Watanabe, Rossella Tozzi, Renata Risi, Dario Tuccinardi, Stefania Mariani, Sabrina Basciani, Giovanni Spera, Carla Lubrano, Lucio Gnessi. Obes Rev 2020
Mikiko Watanabe, Rossella Tozzi, Renata Risi, Dario Tuccinardi, Stefania Mariani, Sabrina Basciani, Giovanni Spera, Carla Lubrano, Lucio Gnessi. Obes Rev 2020
9
Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation.
Zhongyu Xie, Di Zhang, Dongjun Chung, Zhanyun Tang, He Huang, Lunzhi Dai, Shankang Qi, Jingya Li, Gozde Colak, Yue Chen,[...]. Mol Cell 2016
Zhongyu Xie, Di Zhang, Dongjun Chung, Zhanyun Tang, He Huang, Lunzhi Dai, Shankang Qi, Jingya Li, Gozde Colak, Yue Chen,[...]. Mol Cell 2016
6
Ketone Body, 3-Hydroxybutyrate: Minor Metabolite - Major Medical Manifestations.
Niels Møller. J Clin Endocrinol Metab 2020
Niels Møller. J Clin Endocrinol Metab 2020
20
Nutritional Ketosis and Mitohormesis: Potential Implications for Mitochondrial Function and Human Health.
Vincent J Miller, Frederick A Villamena, Jeff S Volek. J Nutr Metab 2018
Vincent J Miller, Frederick A Villamena, Jeff S Volek. J Nutr Metab 2018
6
Empagliflozin Increases Cardiac Energy Production in Diabetes: Novel Translational Insights Into the Heart Failure Benefits of SGLT2 Inhibitors.
Subodh Verma, Sonia Rawat, Kim L Ho, Cory S Wagg, Liyan Zhang, Hwee Teoh, John E Dyck, Golam M Uddin, Gavin Y Oudit, Eric Mayoux,[...]. JACC Basic Transl Sci 2018
Subodh Verma, Sonia Rawat, Kim L Ho, Cory S Wagg, Liyan Zhang, Hwee Teoh, John E Dyck, Golam M Uddin, Gavin Y Oudit, Eric Mayoux,[...]. JACC Basic Transl Sci 2018
5
Metabolism of the human heart. II. Studies on fat, ketone and amino acid metabolism.
R J BING, A SIEGEL, I UNGAR, M GILBERT. Am J Med 1954
R J BING, A SIEGEL, I UNGAR, M GILBERT. Am J Med 1954
5
Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes.
Stephen D Wiviott, Itamar Raz, Marc P Bonaca, Ofri Mosenzon, Eri T Kato, Avivit Cahn, Michael G Silverman, Thomas A Zelniker, Julia F Kuder, Sabina A Murphy,[...]. N Engl J Med 2019
Stephen D Wiviott, Itamar Raz, Marc P Bonaca, Ofri Mosenzon, Eri T Kato, Avivit Cahn, Michael G Silverman, Thomas A Zelniker, Julia F Kuder, Sabina A Murphy,[...]. N Engl J Med 2019
5
Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction.
John J V McMurray, Scott D Solomon, Silvio E Inzucchi, Lars Køber, Mikhail N Kosiborod, Felipe A Martinez, Piotr Ponikowski, Marc S Sabatine, Inder S Anand, Jan Bělohlávek,[...]. N Engl J Med 2019
John J V McMurray, Scott D Solomon, Silvio E Inzucchi, Lars Køber, Mikhail N Kosiborod, Felipe A Martinez, Piotr Ponikowski, Marc S Sabatine, Inder S Anand, Jan Bělohlávek,[...]. N Engl J Med 2019
5
A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.
Megan N Roberts, Marita A Wallace, Alexey A Tomilov, Zeyu Zhou, George R Marcotte, Dianna Tran, Gabriella Perez, Elena Gutierrez-Casado, Shinichiro Koike, Trina A Knotts,[...]. Cell Metab 2017
Megan N Roberts, Marita A Wallace, Alexey A Tomilov, Zeyu Zhou, George R Marcotte, Dianna Tran, Gabriella Perez, Elena Gutierrez-Casado, Shinichiro Koike, Trina A Knotts,[...]. Cell Metab 2017
5
Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice.
John C Newman, Anthony J Covarrubias, Minghao Zhao, Xinxing Yu, Philipp Gut, Che-Ping Ng, Yu Huang, Saptarsi Haldar, Eric Verdin. Cell Metab 2017
John C Newman, Anthony J Covarrubias, Minghao Zhao, Xinxing Yu, Philipp Gut, Che-Ping Ng, Yu Huang, Saptarsi Haldar, Eric Verdin. Cell Metab 2017
5
Fasting: molecular mechanisms and clinical applications.
Valter D Longo, Mark P Mattson. Cell Metab 2014
Valter D Longo, Mark P Mattson. Cell Metab 2014
5
Ketone Body Infusion With 3-Hydroxybutyrate Reduces Myocardial Glucose Uptake and Increases Blood Flow in Humans: A Positron Emission Tomography Study.
Lars C Gormsen, Mads Svart, Henrik Holm Thomsen, Esben Søndergaard, Mikkel H Vendelbo, Nana Christensen, Lars Poulsen Tolbod, Hendrik Johannes Harms, Roni Nielsen, Henrik Wiggers,[...]. J Am Heart Assoc 2017
Lars C Gormsen, Mads Svart, Henrik Holm Thomsen, Esben Søndergaard, Mikkel H Vendelbo, Nana Christensen, Lars Poulsen Tolbod, Hendrik Johannes Harms, Roni Nielsen, Henrik Wiggers,[...]. J Am Heart Assoc 2017
5
(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.
Andrew K P Taggart, Jukka Kero, Xiaodong Gan, Tian-Quan Cai, Kang Cheng, Marc Ippolito, Ning Ren, Rebecca Kaplan, Kenneth Wu, Tsuei-Ju Wu,[...]. J Biol Chem 2005
Andrew K P Taggart, Jukka Kero, Xiaodong Gan, Tian-Quan Cai, Kang Cheng, Marc Ippolito, Ning Ren, Rebecca Kaplan, Kenneth Wu, Tsuei-Ju Wu,[...]. J Biol Chem 2005
5
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.