A citation-based method for searching scientific literature

Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
Times Cited: 783







List of co-cited articles
732 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
30

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
30

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
18

On the origin of cancer cells.
O WARBURG. Science 1956
16

Lactate Metabolism in Human Lung Tumors.
Brandon Faubert, Kevin Y Li, Ling Cai, Christopher T Hensley, Jiyeon Kim, Lauren G Zacharias, Chendong Yang, Quyen N Do, Sarah Doucette, Daniel Burguete,[...]. Cell 2017
455
15

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
15

Targeting Metabolism for Cancer Therapy.
Alba Luengo, Dan Y Gui, Matthew G Vander Heiden. Cell Chem Biol 2017
303
14

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
10

Metabolic Heterogeneity in Human Lung Tumors.
Christopher T Hensley, Brandon Faubert, Qing Yuan, Naama Lev-Cohain, Eunsook Jin, Jiyeon Kim, Lei Jiang, Bookyung Ko, Rachael Skelton, Laurin Loudat,[...]. Cell 2016
509
10

Otto Warburg's contributions to current concepts of cancer metabolism.
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
9

Regulation of cancer cell metabolism.
Rob A Cairns, Isaac S Harris, Tak W Mak. Nat Rev Cancer 2011
9

Glucose feeds the TCA cycle via circulating lactate.
Sheng Hui, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, Tannishtha Reya, Le Zhan, Jessie Yanxiang Guo,[...]. Nature 2017
483
9

Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.
Shawn M Davidson, Thales Papagiannakopoulos, Benjamin A Olenchock, Julia E Heyman, Mark A Keibler, Alba Luengo, Matthew R Bauer, Abhishek K Jha, James P O'Brien, Kerry A Pierce,[...]. Cell Metab 2016
398
8

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion.
Robert D Leone, Liang Zhao, Judson M Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L Arwood, Ian A Bettencourt, Chirag H Patel, Jiayu Wen,[...]. Science 2019
188
8

Serine and one-carbon metabolism in cancer.
Ming Yang, Karen H Vousden. Nat Rev Cancer 2016
347
8

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
8

NRF2 regulates serine biosynthesis in non-small cell lung cancer.
Gina M DeNicola, Pei-Hsuan Chen, Edouard Mullarky, Jessica A Sudderth, Zeping Hu, David Wu, Hao Tang, Yang Xie, John M Asara, Kenneth E Huffman,[...]. Nat Genet 2015
365
7

Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability.
Mark R Sullivan, Laura V Danai, Caroline A Lewis, Sze Ham Chan, Dan Y Gui, Tenzin Kunchok, Emily A Dennstedt, Matthew G Vander Heiden, Alexander Muir. Elife 2019
128
7

Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.
Jason R Cantor, Monther Abu-Remaileh, Naama Kanarek, Elizaveta Freinkman, Xin Gao, Abner Louissaint, Caroline A Lewis, David M Sabatini. Cell 2017
160
7

mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.
Issam Ben-Sahra, Gerta Hoxhaj, Stéphane J H Ricoult, John M Asara, Brendan D Manning. Science 2016
347
7


Metabolic reprogramming and cancer progression.
Brandon Faubert, Ashley Solmonson, Ralph J DeBerardinis. Science 2020
186
7

Dietary methionine influences therapy in mouse cancer models and alters human metabolism.
Xia Gao, Sydney M Sanderson, Ziwei Dai, Michael A Reid, Daniel E Cooper, Min Lu, John P Richie, Amy Ciccarella, Ana Calcagnotto, Peter G Mikhael,[...]. Nature 2019
161
7

Cancer metabolism: a therapeutic perspective.
Ubaldo E Martinez-Outschoorn, Maria Peiris-Pagés, Richard G Pestell, Federica Sotgia, Michael P Lisanti. Nat Rev Clin Oncol 2017
540
7

Glutamine addiction: a new therapeutic target in cancer.
David R Wise, Craig B Thompson. Trends Biochem Sci 2010
981
7

The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
7

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.
Ralph J DeBerardinis, Julian J Lum, Georgia Hatzivassiliou, Craig B Thompson. Cell Metab 2008
6

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Richard Possemato, Kevin M Marks, Yoav D Shaul, Michael E Pacold, Dohoon Kim, Kıvanç Birsoy, Shalini Sethumadhavan, Hin-Koon Woo, Hyun G Jang, Abhishek K Jha,[...]. Nature 2011
929
6

Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting.
Mark R Sullivan, Katherine R Mattaini, Emily A Dennstedt, Anna A Nguyen, Sharanya Sivanand, Montana F Reilly, Katrina Meeth, Alexander Muir, Alicia M Darnell, Marcus W Bosenberg,[...]. Cell Metab 2019
74
8

Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition.
Alexander Muir, Laura V Danai, Dan Y Gui, Chiara Y Waingarten, Caroline A Lewis, Matthew G Vander Heiden. Elife 2017
129
6

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
Cosimo Commisso, Shawn M Davidson, Rengin G Soydaner-Azeloglu, Seth J Parker, Jurre J Kamphorst, Sean Hackett, Elda Grabocka, Michel Nofal, Jeffrey A Drebin, Craig B Thompson,[...]. Nature 2013
831
6

Targeting metastasis-initiating cells through the fatty acid receptor CD36.
Gloria Pascual, Alexandra Avgustinova, Stefania Mejetta, Mercè Martín, Andrés Castellanos, Camille Stephan-Otto Attolini, Antoni Berenguer, Neus Prats, Agustí Toll, Juan Antonio Hueto,[...]. Nature 2017
499
6

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.
Lenny Dang, David W White, Stefan Gross, Bryson D Bennett, Mark A Bittinger, Edward M Driggers, Valeria R Fantin, Hyun Gyung Jang, Shengfang Jin, Marie C Keenan,[...]. Nature 2009
6

Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Oliver D K Maddocks, Dimitris Athineos, Eric C Cheung, Pearl Lee, Tong Zhang, Niels J F van den Broek, Gillian M Mackay, Christiaan F Labuschagne, David Gay, Flore Kruiswijk,[...]. Nature 2017
207
6

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
David R Wise, Ralph J DeBerardinis, Anthony Mancuso, Nabil Sayed, Xiao-Yong Zhang, Harla K Pfeiffer, Ilana Nissim, Evgueni Daikhin, Marc Yudkoff, Steven B McMahon,[...]. Proc Natl Acad Sci U S A 2008
6

THE METABOLISM OF TUMORS IN THE BODY.
O Warburg, F Wind, E Negelein. J Gen Physiol 1927
5


Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.
Katherine Sellers, Matthew P Fox, Michael Bousamra, Stephen P Slone, Richard M Higashi, Donald M Miller, Yali Wang, Jun Yan, Mariia O Yuneva, Rahul Deshpande,[...]. J Clin Invest 2015
278
5

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.
Jessie Yanxiang Guo, Hsin-Yi Chen, Robin Mathew, Jing Fan, Anne M Strohecker, Gizem Karsli-Uzunbas, Jurre J Kamphorst, Guanghua Chen, Johanna M S Lemons, Vassiliki Karantza,[...]. Genes Dev 2011
822
5

Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer.
Wei Li, Takashi Tanikawa, Ilona Kryczek, Houjun Xia, Gaopeng Li, Ke Wu, Shuang Wei, Lili Zhao, Linda Vatan, Bo Wen,[...]. Cell Metab 2018
103
5

From Krebs to clinic: glutamine metabolism to cancer therapy.
Brian J Altman, Zachary E Stine, Chi V Dang. Nat Rev Cancer 2016
642
5

Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells.
Christiaan F Labuschagne, Niels J F van den Broek, Gillian M Mackay, Karen H Vousden, Oliver D K Maddocks. Cell Rep 2014
293
5

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.
Heather R Christofk, Matthew G Vander Heiden, Marian H Harris, Arvind Ramanathan, Robert E Gerszten, Ru Wei, Mark D Fleming, Stuart L Schreiber, Lewis C Cantley. Nature 2008
5

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander,[...]. Proc Natl Acad Sci U S A 2005
5

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth.
Kristin M Nieman, Hilary A Kenny, Carla V Penicka, Andras Ladanyi, Rebecca Buell-Gutbrod, Marion R Zillhardt, Iris L Romero, Mark S Carey, Gordon B Mills, Gökhan S Hotamisligil,[...]. Nat Med 2011
5

An inhibitor of oxidative phosphorylation exploits cancer vulnerability.
Jennifer R Molina, Yuting Sun, Marina Protopopova, Sonal Gera, Madhavi Bandi, Christopher Bristow, Timothy McAfoos, Pietro Morlacchi, Jeffrey Ackroyd, Ahmed-Noor A Agip,[...]. Nat Med 2018
254
5

Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis.
Andras Ladanyi, Abir Mukherjee, Hilary A Kenny, Alyssa Johnson, Anirban K Mitra, Sinju Sundaresan, Kristin M Nieman, Gloria Pascual, Salvador Aznar Benitah, Anthony Montag,[...]. Oncogene 2018
147
5


Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
5

Histidine catabolism is a major determinant of methotrexate sensitivity.
Naama Kanarek, Heather R Keys, Jason R Cantor, Caroline A Lewis, Sze Ham Chan, Tenzin Kunchok, Monther Abu-Remaileh, Elizaveta Freinkman, Lawrence D Schweitzer, David M Sabatini. Nature 2018
101
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.