Pradeep Natarajan, Robin Young, Nathan O Stitziel, Sandosh Padmanabhan, Usman Baber, Roxana Mehran, Samantha Sartori, Valentin Fuster, Dermot F Reilly, Adam Butterworth, Daniel J Rader, Ian Ford, Naveed Sattar, Sekar Kathiresan. Circulation 2017
Times Cited: 212
Times Cited: 212
Times Cited
Times Co-cited
Similarity
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations.
Amit V Khera, Mark Chaffin, Krishna G Aragam, Mary E Haas, Carolina Roselli, Seung Hoan Choi, Pradeep Natarajan, Eric S Lander, Steven A Lubitz, Patrick T Ellinor,[...]. Nat Genet 2018
Amit V Khera, Mark Chaffin, Krishna G Aragam, Mary E Haas, Carolina Roselli, Seung Hoan Choi, Pradeep Natarajan, Eric S Lander, Steven A Lubitz, Patrick T Ellinor,[...]. Nat Genet 2018
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Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.
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Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease.
Amit V Khera, Connor A Emdin, Isabel Drake, Pradeep Natarajan, Alexander G Bick, Nancy R Cook, Daniel I Chasman, Usman Baber, Roxana Mehran, Daniel J Rader,[...]. N Engl J Med 2016
Amit V Khera, Connor A Emdin, Isabel Drake, Pradeep Natarajan, Alexander G Bick, Nancy R Cook, Daniel I Chasman, Usman Baber, Roxana Mehran, Daniel J Rader,[...]. N Engl J Med 2016
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Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention.
Michael Inouye, Gad Abraham, Christopher P Nelson, Angela M Wood, Michael J Sweeting, Frank Dudbridge, Florence Y Lai, Stephen Kaptoge, Marta Brozynska, Tingting Wang,[...]. J Am Coll Cardiol 2018
Michael Inouye, Gad Abraham, Christopher P Nelson, Angela M Wood, Michael J Sweeting, Frank Dudbridge, Florence Y Lai, Stephen Kaptoge, Marta Brozynska, Tingting Wang,[...]. J Am Coll Cardiol 2018
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Predictive Accuracy of a Polygenic Risk Score-Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease.
Joshua Elliott, Barbara Bodinier, Tom A Bond, Marc Chadeau-Hyam, Evangelos Evangelou, Karel G M Moons, Abbas Dehghan, David C Muller, Paul Elliott, Ioanna Tzoulaki. JAMA 2020
Joshua Elliott, Barbara Bodinier, Tom A Bond, Marc Chadeau-Hyam, Evangelos Evangelou, Karel G M Moons, Abbas Dehghan, David C Muller, Paul Elliott, Ioanna Tzoulaki. JAMA 2020
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Patients With High Genome-Wide Polygenic Risk Scores for Coronary Artery Disease May Receive Greater Clinical Benefit From Alirocumab Treatment in the ODYSSEY OUTCOMES Trial.
Amy Damask, P Gabriel Steg, Gregory G Schwartz, Michael Szarek, Emil Hagström, Lina Badimon, M John Chapman, Catherine Boileau, Sotirios Tsimikas, Henry N Ginsberg,[...]. Circulation 2020
Amy Damask, P Gabriel Steg, Gregory G Schwartz, Michael Szarek, Emil Hagström, Lina Badimon, M John Chapman, Catherine Boileau, Sotirios Tsimikas, Henry N Ginsberg,[...]. Circulation 2020
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Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease.
Jonathan D Mosley, Deepak K Gupta, Jingyi Tan, Jie Yao, Quinn S Wells, Christian M Shaffer, Suman Kundu, Cassianne Robinson-Cohen, Bruce M Psaty, Stephen S Rich,[...]. JAMA 2020
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Predicting Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease Using a Genetic Risk Score: Results From the FOURIER Trial.
Nicholas A Marston, Frederick K Kamanu, Francesco Nordio, Yared Gurmu, Carolina Roselli, Peter S Sever, Terje R Pedersen, Anthony C Keech, Huei Wang, Armando Lira Pineda,[...]. Circulation 2020
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Clinical use of current polygenic risk scores may exacerbate health disparities.
Alicia R Martin, Masahiro Kanai, Yoichiro Kamatani, Yukinori Okada, Benjamin M Neale, Mark J Daly. Nat Genet 2019
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A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
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20
Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history.
Hayato Tada, Olle Melander, Judy Z Louie, Joseph J Catanese, Charles M Rowland, James J Devlin, Sekar Kathiresan, Dov Shiffman. Eur Heart J 2016
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The personal and clinical utility of polygenic risk scores.
Ali Torkamani, Nathan E Wineinger, Eric J Topol. Nat Rev Genet 2018
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Genomic prediction of coronary heart disease.
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Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
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Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk Estimates: Effect on Low-Density Lipoprotein Cholesterol Levels (the MI-GENES Clinical Trial).
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A common variant on chromosome 9p21 affects the risk of myocardial infarction.
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Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial Infarction.
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A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses.
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The UK Biobank resource with deep phenotyping and genomic data.
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Large-scale association analysis identifies new risk loci for coronary artery disease.
Panos Deloukas, Stavroula Kanoni, Christina Willenborg, Martin Farrall, Themistocles L Assimes, John R Thompson, Erik Ingelsson, Danish Saleheen, Jeanette Erdmann, Benjamin A Goldstein,[...]. Nat Genet 2013
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Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions.
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Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery Disease.
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A global reference for human genetic variation.
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A decade of genome-wide association studies for coronary artery disease: the challenges ahead.
Jeanette Erdmann, Thorsten Kessler, Loreto Munoz Venegas, Heribert Schunkert. Cardiovasc Res 2018
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Polygenic Scores to Assess Atherosclerotic Cardiovascular Disease Risk: Clinical Perspectives and Basic Implications.
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Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers.
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A common allele on chromosome 9 associated with coronary heart disease.
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Towards clinical utility of polygenic risk scores.
Samuel A Lambert, Gad Abraham, Michael Inouye. Hum Mol Genet 2019
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Improving reporting standards for polygenic scores in risk prediction studies.
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Polymorphisms associated with cholesterol and risk of cardiovascular events.
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Genomewide association analysis of coronary artery disease.
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Tutorial: a guide to performing polygenic risk score analyses.
Shing Wan Choi, Timothy Shin-Heng Mak, Paul F O'Reilly. Nat Protoc 2020
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Discovery and refinement of loci associated with lipid levels.
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Developing and evaluating polygenic risk prediction models for stratified disease prevention.
Nilanjan Chatterjee, Jianxin Shi, Montserrat García-Closas. Nat Rev Genet 2016
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2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
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Association analyses based on false discovery rate implicate new loci for coronary artery disease.
Christopher P Nelson, Anuj Goel, Adam S Butterworth, Stavroula Kanoni, Tom R Webb, Eirini Marouli, Lingyao Zeng, Ioanna Ntalla, Florence Y Lai, Jemma C Hopewell,[...]. Nat Genet 2017
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Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study.
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Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood.
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Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.
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UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age.
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Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations.
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Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.
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Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia.
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Using a genetic risk score to calculate the optimal age for an individual to undergo coronary artery calcium screening.
Lauren M Severance, Francisco J Contijoch, Hannah Carter, Chun C Fan, Tyler M Seibert, Anders M Dale, Elliot R McVeigh. J Cardiovasc Comput Tomogr 2019
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Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians.
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Second-generation PLINK: rising to the challenge of larger and richer datasets.
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8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.