A citation-based method for searching scientific literature

Andrea Piunti, Rintaro Hashizume, Marc A Morgan, Elizabeth T Bartom, Craig M Horbinski, Stacy A Marshall, Emily J Rendleman, Quanhong Ma, Yoh-Hei Takahashi, Ashley R Woodfin, Alexander V Misharin, Nebiyu A Abshiru, Rishi R Lulla, Amanda M Saratsis, Neil L Kelleher, C David James, Ali Shilatifard. Nat Med 2017
Times Cited: 186







List of co-cited articles
1116 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma.
Peter W Lewis, Manuel M Müller, Matthew S Koletsky, Francisco Cordero, Shu Lin, Laura A Banaszynski, Benjamin A Garcia, Tom W Muir, Oren J Becher, C David Allis. Science 2013
708
64

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.
Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu, David T W Jones, Elke Pfaff, Karine Jacob, Dominik Sturm, Adam M Fontebasso, Dong-Anh Khuong Quang, Martje Tönjes,[...]. Nature 2012
63

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas.
Gang Wu, Alberto Broniscer, Troy A McEachron, Charles Lu, Barbara S Paugh, Jared Becksfort, Chunxu Qu, Li Ding, Robert Huether, Matthew Parker,[...]. Nat Genet 2012
927
57

EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas.
Faizaan Mohammad, Simon Weissmann, Benjamin Leblanc, Deo P Pandey, Jonas W Højfeldt, Itys Comet, Chunqin Zheng, Jens Vilstrup Johansen, Nicolas Rapin, Bo T Porse,[...]. Nat Med 2017
227
54

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas.
Sebastian Bender, Yujie Tang, Anders M Lindroth, Volker Hovestadt, David T W Jones, Marcel Kool, Marc Zapatka, Paul A Northcott, Dominik Sturm, Wei Wang,[...]. Cancer Cell 2013
395
47

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression.
Kui-Ming Chan, Dong Fang, Haiyun Gan, Rintaro Hashizume, Chuanhe Yu, Mark Schroeder, Nalin Gupta, Sabine Mueller, C David James, Robert Jenkins,[...]. Genes Dev 2013
402
39

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.
Alan Mackay, Anna Burford, Diana Carvalho, Elisa Izquierdo, Janat Fazal-Salom, Kathryn R Taylor, Lynn Bjerke, Matthew Clarke, Mara Vinci, Meera Nandhabalan,[...]. Cancer Cell 2017
325
39

Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.
Rintaro Hashizume, Noemi Andor, Yuichiro Ihara, Robin Lerner, Haiyun Gan, Xiaoyue Chen, Dong Fang, Xi Huang, Maxwell W Tom, Vy Ngo,[...]. Nat Med 2014
276
32

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.
David N Louis, Arie Perry, Guido Reifenberger, Andreas von Deimling, Dominique Figarella-Branger, Webster K Cavenee, Hiroko Ohgaki, Otmar D Wiestler, Paul Kleihues, David W Ellison. Acta Neuropathol 2016
31

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.
Dominik Sturm, Hendrik Witt, Volker Hovestadt, Dong-Anh Khuong-Quang, David T W Jones, Carolin Konermann, Elke Pfaff, Martje Tönjes, Martin Sill, Sebastian Bender,[...]. Cancer Cell 2012
31

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.
Catherine S Grasso, Yujie Tang, Nathalene Truffaux, Noah E Berlow, Lining Liu, Marie-Anne Debily, Michael J Quist, Lara E Davis, Elaine C Huang, Pamelyn J Woo,[...]. Nat Med 2015
261
31

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas.
Dong-Anh Khuong-Quang, Pawel Buczkowicz, Patricia Rakopoulos, Xiao-Yang Liu, Adam M Fontebasso, Eric Bouffet, Ute Bartels, Steffen Albrecht, Jeremy Schwartzentruber, Louis Letourneau,[...]. Acta Neuropathol 2012
526
30

Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression.
Jon D Larson, Lawryn H Kasper, Barbara S Paugh, Hongjian Jin, Gang Wu, Chang-Hyuk Kwon, Yiping Fan, Timothy I Shaw, André B Silveira, Chunxu Qu,[...]. Cancer Cell 2019
86
33

Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma.
Surya Nagaraja, Nicholas A Vitanza, Pamelyn J Woo, Kathryn R Taylor, Fang Liu, Lei Zhang, Meng Li, Wei Meng, Anitha Ponnuswami, Wenchao Sun,[...]. Cancer Cell 2017
151
29

Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation.
Kosuke Funato, Tamara Major, Peter W Lewis, C David Allis, Viviane Tabar. Science 2014
212
27

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq.
Mariella G Filbin, Itay Tirosh, Volker Hovestadt, McKenzie L Shaw, Leah E Escalante, Nathan D Mathewson, Cyril Neftel, Nelli Frank, Kristine Pelton, Christine M Hebert,[...]. Science 2018
190
27

Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Neil Justin, Ying Zhang, Cataldo Tarricone, Stephen R Martin, Shuyang Chen, Elizabeth Underwood, Valeria De Marco, Lesley F Haire, Philip A Walker, Danny Reinberg,[...]. Nat Commun 2016
200
26

Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas.
Brian Krug, Nicolas De Jay, Ashot S Harutyunyan, Shriya Deshmukh, Dylan M Marchione, Paul Guilhamon, Kelsey C Bertrand, Leonie G Mikael, Melissa K McConechy, Carol C L Chen,[...]. Cancer Cell 2019
39
64

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes.
David Castel, Cathy Philippe, Raphaël Calmon, Ludivine Le Dret, Nathalène Truffaux, Nathalie Boddaert, Mélanie Pagès, Kathryn R Taylor, Patrick Saulnier, Ludovic Lacroix,[...]. Acta Neuropathol 2015
260
25

Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma.
James M Stafford, Chul-Hwan Lee, Philipp Voigt, Nicolas Descostes, Ricardo Saldaña-Meyer, Jia-Ray Yu, Gary Leroy, Ozgur Oksuz, Jessica R Chapman, Fernando Suarez,[...]. Sci Adv 2018
64
39

H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis.
Ashot S Harutyunyan, Brian Krug, Haifen Chen, Simon Papillon-Cavanagh, Michele Zeinieh, Nicolas De Jay, Shriya Deshmukh, Carol C L Chen, Jad Belle, Leonie G Mikael,[...]. Nat Commun 2019
74
32

Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State.
Surya Nagaraja, Michael A Quezada, Shawn M Gillespie, Marlene Arzt, James J Lennon, Pamelyn J Woo, Volker Hovestadt, Madhuri Kambhampati, Mariella G Filbin, Mario L Suva,[...]. Mol Cell 2019
39
58

H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas.
Manav Pathania, Nicolas De Jay, Nicola Maestro, Ashot S Harutyunyan, Justyna Nitarska, Pirasteh Pahlavan, Stephen Henderson, Leonie G Mikael, Angela Richard-Londt, Ying Zhang,[...]. Cancer Cell 2017
93
23

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.
Gang Wu, Alexander K Diaz, Barbara S Paugh, Sherri L Rankin, Bensheng Ju, Yongjin Li, Xiaoyan Zhu, Chunxu Qu, Xiang Chen, Junyuan Zhang,[...]. Nat Genet 2014
557
22

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations.
Pawel Buczkowicz, Christine Hoeman, Patricia Rakopoulos, Sanja Pajovic, Louis Letourneau, Misko Dzamba, Andrew Morrison, Peter Lewis, Eric Bouffet, Ute Bartels,[...]. Nat Genet 2014
340
22

Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
Adam M Fontebasso, Simon Papillon-Cavanagh, Jeremy Schwartzentruber, Hamid Nikbakht, Noha Gerges, Pierre-Olivier Fiset, Denise Bechet, Damien Faury, Nicolas De Jay, Lori A Ramkissoon,[...]. Nat Genet 2014
247
21

Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling.
Hans-Martin Herz, Marc Morgan, Xin Gao, Jessica Jackson, Ryan Rickels, Selene K Swanson, Laurence Florens, Michael P Washburn, Joel C Eissenberg, Ali Shilatifard. Science 2014
115
21

Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG.
Francisco J Cordero, Zhiqing Huang, Carole Grenier, Xingyao He, Guo Hu, Roger E McLendon, Susan K Murphy, Rintaro Hashizume, Oren J Becher. Mol Cancer Res 2017
63
31

Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.
Chao Lu, Siddhant U Jain, Dominik Hoelper, Denise Bechet, Rosalynn C Molden, Leili Ran, Devan Murphy, Sriram Venneti, Meera Hameed, Bruce R Pawel,[...]. Science 2016
191
19

H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo.
André B Silveira, Lawryn H Kasper, Yiping Fan, Hongjian Jin, Gang Wu, Timothy I Shaw, Xiaoyan Zhu, Jon D Larson, John Easton, Ying Shao,[...]. Acta Neuropathol 2019
35
54

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma.
Kathryn R Taylor, Alan Mackay, Nathalène Truffaux, Yaron Butterfield, Olena Morozova, Cathy Philippe, David Castel, Catherine S Grasso, Maria Vinci, Diana Carvalho,[...]. Nat Genet 2014
289
17

H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers.
Dong Fang, Haiyun Gan, Liang Cheng, Jeong-Heon Lee, Hui Zhou, Jann N Sarkaria, David J Daniels, Zhiguo Zhang. Elife 2018
35
48

PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism.
Siddhant U Jain, Truman J Do, Peder J Lund, Andrew Q Rashoff, Katharine L Diehl, Marcin Cieslik, Andrea Bajic, Nikoleta Juretic, Shriya Deshmukh, Sriram Venneti,[...]. Nat Commun 2019
60
28

Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma.
Hamid Nikbakht, Eshini Panditharatna, Leonie G Mikael, Rui Li, Tenzin Gayden, Matthew Osmond, Cheng-Ying Ho, Madhuri Kambhampati, Eugene I Hwang, Damien Faury,[...]. Nat Commun 2016
126
16

The expanding landscape of 'oncohistone' mutations in human cancers.
Benjamin A Nacev, Lijuan Feng, John D Bagert, Agata E Lemiesz, JianJiong Gao, Alexey A Soshnev, Ritika Kundra, Nikolaus Schultz, Tom W Muir, C David Allis. Nature 2019
112
15

Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.
Sam Behjati, Patrick S Tarpey, Nadège Presneau, Susanne Scheipl, Nischalan Pillay, Peter Van Loo, David C Wedge, Susanna L Cooke, Gunes Gundem, Helen Davies,[...]. Nat Genet 2013
385
14

EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma.
Jens-Martin Hübner, Torsten Müller, Dimitris N Papageorgiou, Monika Mauermann, Jeroen Krijgsveld, Robert B Russell, David W Ellison, Stefan M Pfister, Kristian W Pajtler, Marcel Kool. Neuro Oncol 2019
51
27

Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas.
Christopher W Mount, Robbie G Majzner, Shree Sundaresh, Evan P Arnold, Meena Kadapakkam, Samuel Haile, Louai Labanieh, Esther Hulleman, Pamelyn J Woo, Skyler P Rietberg,[...]. Nat Med 2018
135
14

Cancer-driving H3G34V/R/D mutations block H3K36 methylation and H3K36me3-MutSα interaction.
Jun Fang, Yaping Huang, Guogen Mao, Shuang Yang, Gadi Rennert, Liya Gu, Haitao Li, Guo-Min Li. Proc Natl Acad Sci U S A 2018
43
32

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG.
Jamie N Anastas, Barry M Zee, Jay H Kalin, Mirhee Kim, Robyn Guo, Sanda Alexandrescu, Mario Andres Blanco, Stefanie Giera, Shawn M Gillespie, Jayanta Das,[...]. Cancer Cell 2019
51
27

Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas.
Sriram Venneti, Mihir T Garimella, Lisa M Sullivan, Daniel Martinez, Jason T Huse, Adriana Heguy, Mariarita Santi, Craig B Thompson, Alexander R Judkins. Brain Pathol 2013
136
13


The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas.
Dong Fang, Haiyun Gan, Jeong-Heon Lee, Jing Han, Zhiquan Wang, Scott M Riester, Long Jin, Jianji Chen, Hui Zhou, Jinglong Wang,[...]. Science 2016
130
13

Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma.
Michelle Monje, Siddhartha S Mitra, Morgan E Freret, Tal B Raveh, James Kim, Marilyn Masek, Joanne L Attema, Gordon Li, Terri Haddix, Michael S B Edwards,[...]. Proc Natl Acad Sci U S A 2011
170
13

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.
Catherine S Grasso, Yujie Tang, Nathalene Truffaux, Noah E Berlow, Lining Liu, Marie-Anne Debily, Michael J Quist, Lara E Davis, Elaine C Huang, Pamelyn J Woo,[...]. Nat Med 2015
72
18

Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models.
Tammy Hennika, Guo Hu, Nagore G Olaciregui, Kelly L Barton, Anahid Ehteda, Arjanna Chitranjan, Cecilia Chang, Andrew J Gifford, Maria Tsoli, David S Ziegler,[...]. PLoS One 2017
78
16

Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.
Kristian W Pajtler, Ji Wen, Martin Sill, Tong Lin, Wilda Orisme, Bo Tang, Jens-Martin Hübner, Vijay Ramaswamy, Sujuan Jia, James D Dalton,[...]. Acta Neuropathol 2018
86
13

Role of the polycomb protein EED in the propagation of repressive histone marks.
Raphael Margueron, Neil Justin, Katsuhito Ohno, Miriam L Sharpe, Jinsook Son, William J Drury, Philipp Voigt, Stephen R Martin, William R Taylor, Valeria De Marco,[...]. Nature 2009
724
12

Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma.
Hsiao P J Voon, Maheshi Udugama, Wendi Lin, Linda Hii, Ruby H P Law, David L Steer, Partha P Das, Jeffrey R Mann, Lee H Wong. Nat Commun 2018
25
48

The Polycomb complex PRC2 and its mark in life.
Raphaël Margueron, Danny Reinberg. Nature 2011
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.