A citation-based method for searching scientific literature

Robert A Saxton, David M Sabatini. Cell 2017
Times Cited: 2525







List of co-cited articles
378 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
8

mTOR at the nexus of nutrition, growth, ageing and disease.
Grace Y Liu, David M Sabatini. Nat Rev Mol Cell Biol 2020
504
8

mTOR signaling in growth control and disease.
Mathieu Laplante, David M Sabatini. Cell 2012
7

AMPK phosphorylation of raptor mediates a metabolic checkpoint.
Dana M Gwinn, David B Shackelford, Daniel F Egan, Maria M Mihaylova, Annabelle Mery, Debbie S Vasquez, Benjamin E Turk, Reuben J Shaw. Mol Cell 2008
6

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
D D Sarbassov, Siraj M Ali, Do-Hyung Kim, David A Guertin, Robert R Latek, Hediye Erdjument-Bromage, Paul Tempst, David M Sabatini. Curr Biol 2004
6


Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
6

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
Yasemin Sancak, Timothy R Peterson, Yoav D Shaul, Robert A Lindquist, Carson C Thoreen, Liron Bar-Peled, David M Sabatini. Science 2008
6

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.
Yasemin Sancak, Liron Bar-Peled, Roberto Zoncu, Andrew L Markhard, Shigeyuki Nada, David M Sabatini. Cell 2010
6

mTOR: a pharmacologic target for autophagy regulation.
Young Chul Kim, Kun-Liang Guan. J Clin Invest 2015
836
6

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.
D D Sarbassov, David A Guertin, Siraj M Ali, David M Sabatini. Science 2005
6

mTORC1 as the main gateway to autophagy.
Yoana Rabanal-Ruiz, Elsje G Otten, Viktor I Korolchuk. Essays Biochem 2017
213
5

AMPK: guardian of metabolism and mitochondrial homeostasis.
Sébastien Herzig, Reuben J Shaw. Nat Rev Mol Cell Biol 2018
5

TFEB links autophagy to lysosomal biogenesis.
Carmine Settembre, Chiara Di Malta, Vinicia Assunta Polito, Moises Garcia Arencibia, Francesco Vetrini, Serkan Erdin, Serpil Uckac Erdin, Tuong Huynh, Diego Medina, Pasqualina Colella,[...]. Science 2011
5

On the origin of cancer cells.
O WARBURG. Science 1956
5

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
5

The Dawn of the Age of Amino Acid Sensors for the mTORC1 Pathway.
Rachel L Wolfson, David M Sabatini. Cell Metab 2017
271
5

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander,[...]. Proc Natl Acad Sci U S A 2005
5

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
5

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
Estela Jacinto, Robbie Loewith, Anja Schmidt, Shuo Lin, Markus A Rüegg, Alan Hall, Michael N Hall. Nat Cell Biol 2004
5

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism.
Seung-Hoi Koo, Lawrence Flechner, Ling Qi, Xinmin Zhang, Robert A Screaton, Shawn Jeffries, Susan Hedrick, Wu Xu, Fayçal Boussouar, Paul Brindle,[...]. Nature 2005
709
4

mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy.
Tian Tian, Xiaoyi Li, Jinhua Zhang. Int J Mol Sci 2019
206
4

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.
Do-Hyung Kim, D D Sarbassov, Siraj M Ali, Jessie E King, Robert R Latek, Hediye Erdjument-Bromage, Paul Tempst, David M Sabatini. Cell 2002
4

Amino acid-dependent control of mTORC1 signaling: a variety of regulatory modes.
Terunao Takahara, Yuna Amemiya, Risa Sugiyama, Masatoshi Maki, Hideki Shibata. J Biomed Sci 2020
32
12

mTOR Signaling in Growth, Metabolism, and Disease.
Robert A Saxton, David M Sabatini. Cell 2017
944
4

A guide to immunometabolism for immunologists.
Luke A J O'Neill, Rigel J Kishton, Jeff Rathmell. Nat Rev Immunol 2016
4

Regulation of mTORC1 by PI3K signaling.
Christian C Dibble, Lewis C Cantley. Trends Cell Biol 2015
413
4

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
4

Nutrient regulation of mTORC1 at a glance.
Kendall J Condon, David M Sabatini. J Cell Sci 2019
98
4

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism.
A C Gingras, S P Gygi, B Raught, R D Polakiewicz, R T Abraham, M F Hoekstra, R Aebersold, N Sonenberg. Genes Dev 1999
934
4


mTOR kinase structure, mechanism and regulation.
Haijuan Yang, Derek G Rudge, Joseph D Koos, Bhamini Vaidialingam, Hyo J Yang, Nikola P Pavletich. Nature 2013
555
4

The translational landscape of mTOR signalling steers cancer initiation and metastasis.
Andrew C Hsieh, Yi Liu, Merritt P Edlind, Nicholas T Ingolia, Matthew R Janes, Annie Sher, Evan Y Shi, Craig R Stumpf, Carly Christensen, Michael J Bonham,[...]. Nature 2012
829
4

Activation of a metabolic gene regulatory network downstream of mTOR complex 1.
Katrin Düvel, Jessica L Yecies, Suchithra Menon, Pichai Raman, Alex I Lipovsky, Amanda L Souza, Ellen Triantafellow, Qicheng Ma, Regina Gorski, Stephen Cleaver,[...]. Mol Cell 2010
4

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
John T Cunningham, Joseph T Rodgers, Daniel H Arlow, Francisca Vazquez, Vamsi K Mootha, Pere Puigserver. Nature 2007
966
4

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.
Tatsuya Saitoh, Naonobu Fujita, Myoung Ho Jang, Satoshi Uematsu, Bo-Gie Yang, Takashi Satoh, Hiroko Omori, Takeshi Noda, Naoki Yamamoto, Masaaki Komatsu,[...]. Nature 2008
3


Autophagy: cellular and molecular mechanisms.
Danielle Glick, Sandra Barth, Kay F Macleod. J Pathol 2010
3

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.
Timothy R Peterson, Shomit S Sengupta, Thurl E Harris, Anne E Carmack, Seong A Kang, Eric Balderas, David A Guertin, Katherine L Madden, Anne E Carpenter, Brian N Finck,[...]. Cell 2011
709
3

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.
Adem Kalender, Anand Selvaraj, So Young Kim, Pawan Gulati, Sophie Brûlé, Benoit Viollet, Bruce E Kemp, Nabeel Bardeesy, Patrick Dennis, John J Schlager,[...]. Cell Metab 2010
587
3


AMPK: Sensing Glucose as well as Cellular Energy Status.
Sheng-Cai Lin, D Grahame Hardie. Cell Metab 2018
380
3


Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.
Daniel F Egan, David B Shackelford, Maria M Mihaylova, Sara Gelino, Rebecca A Kohnz, William Mair, Debbie S Vasquez, Aashish Joshi, Dana M Gwinn, Rebecca Taylor,[...]. Science 2011
3

The mammalian ULK1 complex and autophagy initiation.
Maria Zachari, Ian G Ganley. Essays Biochem 2017
261
3

Regulation of mammalian autophagy in physiology and pathophysiology.
Brinda Ravikumar, Sovan Sarkar, Janet E Davies, Marie Futter, Moises Garcia-Arencibia, Zeyn W Green-Thompson, Maria Jimenez-Sanchez, Viktor I Korolchuk, Maike Lichtenberg, Shouqing Luo,[...]. Physiol Rev 2010
3

The complex relationship between TFEB transcription factor phosphorylation and subcellular localization.
Rosa Puertollano, Shawn M Ferguson, James Brugarolas, Andrea Ballabio. EMBO J 2018
184
3

The role of Atg proteins in autophagosome formation.
Noboru Mizushima, Tamotsu Yoshimori, Yoshinori Ohsumi. Annu Rev Cell Dev Biol 2011
3

Metabolic Control of Longevity.
Carlos López-Otín, Lorenzo Galluzzi, José M P Freije, Frank Madeo, Guido Kroemer. Cell 2016
354
3

Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition.
David J Roberts, Valerie P Tan-Sah, Eric Y Ding, Jeffery M Smith, Shigeki Miyamoto. Mol Cell 2014
162
3


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.